JP2012500197A5 - - Google Patents

Download PDF

Info

Publication number
JP2012500197A5
JP2012500197A5 JP2011523005A JP2011523005A JP2012500197A5 JP 2012500197 A5 JP2012500197 A5 JP 2012500197A5 JP 2011523005 A JP2011523005 A JP 2011523005A JP 2011523005 A JP2011523005 A JP 2011523005A JP 2012500197 A5 JP2012500197 A5 JP 2012500197A5
Authority
JP
Japan
Prior art keywords
compound
cancer
cells
cell
rassf1a
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011523005A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012500197A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/004681 external-priority patent/WO2010019271A1/en
Publication of JP2012500197A publication Critical patent/JP2012500197A/ja
Publication of JP2012500197A5 publication Critical patent/JP2012500197A5/ja
Pending legal-status Critical Current

Links

JP2011523005A 2008-08-15 2009-08-14 Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤 Pending JP2012500197A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18905908P 2008-08-15 2008-08-15
US61/189,059 2008-08-15
PCT/US2009/004681 WO2010019271A1 (en) 2008-08-15 2009-08-14 Fluorescent regulators of rassf1a expression and human cancer cell proliferation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014105150A Division JP2014148545A (ja) 2008-08-15 2014-05-21 Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤

Publications (2)

Publication Number Publication Date
JP2012500197A JP2012500197A (ja) 2012-01-05
JP2012500197A5 true JP2012500197A5 (enExample) 2013-05-09

Family

ID=41279343

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011523005A Pending JP2012500197A (ja) 2008-08-15 2009-08-14 Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤
JP2014105150A Pending JP2014148545A (ja) 2008-08-15 2014-05-21 Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014105150A Pending JP2014148545A (ja) 2008-08-15 2014-05-21 Ｒａｓｓｆ１ａ発現およびヒト癌細胞増殖の蛍光調節剤

Country Status (9)

Country Link
US (1) US10457639B2 (enExample)
EP (2) EP2484666A1 (enExample)
JP (2) JP2012500197A (enExample)
CN (1) CN102186820B (enExample)
AT (1) ATE547403T1 (enExample)
AU (1) AU2009282451B2 (enExample)
BR (1) BRPI0917411A2 (enExample)
CA (1) CA2734225A1 (enExample)
WO (1) WO2010019271A1 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
PE20130649A1 (es) 2010-03-08 2013-07-13 Monsanto Technology Llc Moleculas polinucleotidicas para regulacion genetica en plantas
US8637679B2 (en) 2011-03-11 2014-01-28 Council Of Scientific And Industrial Research Process for the isolation of organic compounds useful for the treatment of cancer
EP3434779A1 (en) 2011-09-13 2019-01-30 Monsanto Technology LLC Methods and compositions for weed control
WO2013040116A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control
EP2755466A4 (en) 2011-09-13 2015-04-15 Monsanto Technology Llc METHOD AND COMPOSITIONS FOR WEED CONTROL
CN103957697B (zh) 2011-09-13 2017-10-24 孟山都技术公司 用于杂草控制的方法和组合物
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
MX343072B (es) 2011-09-13 2016-10-21 Monsanto Technology Llc Metodos y composiciones para controlar malezas.
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
US10240162B2 (en) 2012-05-24 2019-03-26 A.B. Seeds Ltd. Compositions and methods for silencing gene expression
UA118841C2 (uk) 2013-01-01 2019-03-25 Ей.Бі. СІДС ЛТД. Спосіб формування рослини, яка має підвищену стійкість до комахи-шкідника
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
EP2967082A4 (en) 2013-03-13 2016-11-02 Monsanto Technology Llc METHOD AND COMPOSITIONS FOR WEED CONTROL
WO2014164761A1 (en) 2013-03-13 2014-10-09 Monsanto Technology Llc Methods and compositions for weed control
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
WO2014151317A1 (en) * 2013-03-15 2014-09-25 Rush University Medical Center Methods for treating cancer
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
JP6668236B2 (ja) 2013-07-19 2020-03-18 モンサント テクノロジー エルエルシー Ｌｅｐｔｉｎｏｔａｒｓａ防除用組成物及びその方法
MX390055B (es) 2013-11-04 2025-03-20 Monsanto Technology Llc Composiciones y metodos para controlar infestaciones de plagas y parasitos de los artropodos.
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
CN105979770B (zh) 2014-01-15 2019-07-05 孟山都技术公司 用于使用epsps多核苷酸的杂草控制的方法和组合物
BR112016022711A2 (pt) 2014-04-01 2017-10-31 Monsanto Technology Llc composições e métodos para controle de pragas de inseto
WO2015200223A1 (en) 2014-06-23 2015-12-30 Monsanto Technology Llc Compositions and methods for regulating gene expression via rna interference
US11807857B2 (en) 2014-06-25 2023-11-07 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
AU2015296700B2 (en) 2014-07-29 2021-10-21 Monsanto Technology Llc Compositions and methods for controlling insect pests
US10968449B2 (en) 2015-01-22 2021-04-06 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
US10883103B2 (en) 2015-06-02 2021-01-05 Monsanto Technology Llc Compositions and methods for delivery of a polynucleotide into a plant
EP3302030A4 (en) 2015-06-03 2019-04-24 Monsanto Technology LLC METHOD AND COMPOSITIONS FOR INTRODUCING NUCLEIC ACIDS IN PLANTS
US10173978B2 (en) * 2015-08-05 2019-01-08 Georgetown University Small molecule androgen receptor inhibitors and methods of use thereof
US11464750B2 (en) 2017-06-12 2022-10-11 Shohei Miyata Anticancer agent and use thereof
CN107266356B (zh) * 2017-07-25 2020-06-26 山西省生物研究院有限公司 一种作为自分泌运动因子抑制剂的咔唑类化合物及其制备方法和应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2235815A1 (de) * 1972-07-21 1974-01-31 Bayer Ag Polyazofarbstoffe
WO1988001213A1 (en) 1986-08-18 1988-02-25 Clinical Technologies Associates, Inc. Delivery systems for pharmacological agents
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
NZ241954A (en) 1991-03-15 1994-01-26 Amgen Inc Compositions of g-csf for pulmonary administration.
GB9215361D0 (en) 1992-07-20 1992-09-02 Wellcome Found Heterocyclic compounds
WO1995003279A1 (en) 1993-07-26 1995-02-02 Eisai Co., Ltd. Sulfonamide and sulfonic ester derivatives each having tricyclic hetero ring
JP3690825B2 (ja) * 1993-07-26 2005-08-31 エーザイ株式会社 三環式ヘテロ環含有スルホンアミドおよびスルホン酸エステル誘導体
CA2186412A1 (en) 1995-10-31 1997-05-01 Katherine S. Takaki Ethylamino carbazole melatonergic agents
WO1999032463A1 (en) 1997-12-22 1999-07-01 Bayer Corporation INHIBITION OF p38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS
WO2000063171A1 (en) * 1999-04-20 2000-10-26 Meiji Seika Kaisha, Ltd. Tricyclic compounds
CA2394778A1 (en) 1999-12-16 2002-06-14 Shiro Miyoshi Novel substituted tricyclic compounds
WO2001083452A1 (en) 2000-04-28 2001-11-08 Asahi Kasei Kabushiki Kaisha Novel tricyclic compounds
US6506901B2 (en) * 2000-07-17 2003-01-14 Wyeth Substituted 2-(S)-hydroxy-3-(piperidin-4-yl-methylamino)-propyl ethers and substituted 2-aryl-2-(R)-hydroxy-1-(piperidin-4-yl-methyl)-ethylamine β-3 adrenergic receptor agonists
EP1847263A3 (en) 2000-12-18 2009-08-26 Institute of Medicinal Molecular Design, Inc. Inhibitors against the production and release of inflammatory cytokines
AU2002228316A1 (en) * 2001-01-29 2002-08-12 Insight Strategy And Marketing Ltd Carbazole derivatives and their uses as heparanase inhibitors
JPWO2002074306A1 (ja) 2001-03-19 2004-07-08 旭化成ファーマ株式会社 脂肪肝治療薬
GB0319151D0 (en) 2003-08-14 2003-09-17 Glaxo Group Ltd Novel compounds
US20100063126A1 (en) 2004-06-29 2010-03-11 Jadolabs Gmbh Carbazole-Derived Pharmaceutical Compositions
ATE381540T1 (de) 2004-08-18 2008-01-15 Ciba Sc Holding Ag Oximesther-fotoinitiatoren
ITMI20051523A1 (it) 2005-08-03 2007-02-04 Acraf Composto del 3-ammino-carbazolo composizione farmaceutica che lo contiene e metodo per prepararlo
GB2443588B (en) 2005-09-01 2010-04-21 Council Scient Ind Res A pharmaceutical composition useful for the treatment of prostate cancer
CN1807413B (zh) * 2005-09-28 2010-05-05 中国医学科学院医药生物技术研究所 咔唑磺酰胺衍生物及其制备方法
CA2625219A1 (en) * 2005-10-13 2007-04-19 Orchid Research Laboratories Limited Heterocyclic compounds as pstat3/il-6 inhibitors
WO2008051523A2 (en) 2006-10-23 2008-05-02 Georgetown University Carbazole derivatives useful as medicaments in cancer therapy
IL186935A0 (en) * 2006-10-31 2008-02-09 Veridex Llc Prostate cancer field effect analysis methods and kits
CA2710520A1 (en) * 2007-12-28 2009-07-09 John Wayne Cancer Institute Use of methylation status of mint loci and tumor-related genes as a marker for melanoma and breast cancer
AU2009228765B2 (en) 2008-03-24 2012-05-31 Novartis Ag Arylsulfonamide-based matrix metalloprotease inhibitors

Similar Documents

Publication Publication Date Title
US9138418B2 (en) Therapeutic compositions and methods for delivery of active agents cleavably linked to nanoparticles
US20220153738A1 (en) Compositions and methods for modulating hair growth
ES2665539T3 (es) Derivados de benzamida para inhibir la actividad de ABL1, ABL2 y BCR-ABL1
US10426753B2 (en) Supramolecular combinatorial therapeutics
NZ588583A (en) Novel lipid formulations for nucleic acid delivery
Sun et al. Anti-miRNA oligonucleotide therapy for chondrosarcoma
EP3791897A1 (en) Hsp90 inhibitor drug conjugates
US20220048908A1 (en) Compositions and methods for modulating hair growth
JP2019511491A5 (enExample)
US11976092B2 (en) RNA nanostructures, methods of making, and uses thereof
US20110034545A1 (en) Double-stranded lipid-modified rna having high rna interference effect
JP2021502346A5 (enExample)
US20200108089A1 (en) Gemcitabine Derivatives for Cancer Therapy
MY157187A (en) Drug delivery system for administration of a water soluble, cationic and amphiphilic pharmaceutically active substance
US20220372493A1 (en) Rna nanoparticle for liver cancer treatment
JP2025507982A (ja) 活性分子送達に利用可能な分解性リポソーム及びそのナノ複合体
WO2022061299A1 (en) Non-invasive functional companion assays for oncogene targeted therapy for brain cancer
Srinivas The rationality for using prodrug approach in drug discovery programs for new xenobiotics: opportunities and challenges
JP2024063189A (ja) 血液脳関門透過能を有するペプチド核酸複合体及びこれを含む組成物
US11786545B2 (en) Compositions and methods for treating SARS-CoV-2 infection
US11649457B2 (en) Methods for treating SARS-CoV-2 infection
TW201620504A (zh) 局部投與用脂質複合體之新穎製造方法及使用該脂質複合體之抗腫瘤劑
JP2012516830A (ja) 医薬物質としてのアミノ酸誘導体
US20220040338A1 (en) Alpha Emitter Compositions And Methods
US20250082765A1 (en) Molecules as anticancer agents for targeted treatment of breast and prostate cancer