JP2018536637A5 - - Google Patents

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Publication number
JP2018536637A5
JP2018536637A5 JP2018519321A JP2018519321A JP2018536637A5 JP 2018536637 A5 JP2018536637 A5 JP 2018536637A5 JP 2018519321 A JP2018519321 A JP 2018519321A JP 2018519321 A JP2018519321 A JP 2018519321A JP 2018536637 A5 JP2018536637 A5 JP 2018536637A5
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JP
Japan
Prior art keywords
alkyl
compound according
substituted
ester
substituents
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JP2018519321A
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English (en)
Japanese (ja)
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JP6938485B2 (ja
JP2018536637A (ja
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Priority claimed from PCT/US2016/056714 external-priority patent/WO2017066366A1/en
Publication of JP2018536637A publication Critical patent/JP2018536637A/ja
Publication of JP2018536637A5 publication Critical patent/JP2018536637A5/ja
Application granted granted Critical
Publication of JP6938485B2 publication Critical patent/JP6938485B2/ja
Active legal-status Critical Current
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JP2018519321A 2015-10-14 2016-10-13 選択的nr2bアンタゴニスト Active JP6938485B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN3308/DEL/2015 2015-10-14
IN3308DE2015 2015-10-14
PCT/US2016/056714 WO2017066366A1 (en) 2015-10-14 2016-10-13 Selective nr2b antagonists

Publications (3)

Publication Number Publication Date
JP2018536637A JP2018536637A (ja) 2018-12-13
JP2018536637A5 true JP2018536637A5 (enExample) 2019-11-21
JP6938485B2 JP6938485B2 (ja) 2021-09-22

Family

ID=57223768

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018519321A Active JP6938485B2 (ja) 2015-10-14 2016-10-13 選択的nr2bアンタゴニスト

Country Status (13)

Country Link
US (2) US10344020B2 (enExample)
EP (1) EP3362441B1 (enExample)
JP (1) JP6938485B2 (enExample)
KR (1) KR20180063306A (enExample)
CN (1) CN108137543B (enExample)
AU (1) AU2016340237A1 (enExample)
BR (1) BR112018006537A2 (enExample)
CA (1) CA3001890A1 (enExample)
EA (1) EA201890946A1 (enExample)
ES (1) ES2818254T3 (enExample)
IL (1) IL258603A (enExample)
MX (1) MX2018004256A (enExample)
WO (1) WO2017066366A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202237103A (zh) * 2020-12-04 2022-10-01 瑞士商諾華公司 用於治療抑鬱症的nr2b-nmda受體nam之劑量方案
US11646085B2 (en) 2021-06-17 2023-05-09 Sandisk Technologies Llc Toggle mode frequency optimization by dynamic ODT matching for non-volatile memory
CN116354923B (zh) * 2021-12-27 2025-05-09 江苏恩华药业股份有限公司 一种含氮杂环化合物及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6960589B2 (en) 2001-03-09 2005-11-01 Abbott Laboratories Benzimidazoles that are useful in treating sexual dysfunction
US7022728B2 (en) * 2001-03-09 2006-04-04 Abbott Laboratories Benzimidazoles that are useful in treating male sexual dysfunction
MXPA05013151A (es) 2003-06-04 2006-03-17 Merck & Co Inc 3-fluoro-piperidinas como antagonistas de n-metil-d-aspartato/nr2b.
US7935706B2 (en) 2006-02-23 2011-05-03 Shionogi & Co., Ltd. Nitrogen-containing heterocycle derivatives substituted with cyclic group
CN101815518B (zh) 2007-06-29 2013-01-09 埃莫里大学 用于神经保护的nmda受体拮抗剂
JP2009067784A (ja) * 2007-08-21 2009-04-02 Shionogi & Co Ltd 環式基で置換された含窒素複素環誘導体を含有する鎮痛剤
EP2163541A1 (en) 2008-09-12 2010-03-17 Bayer Schering Pharma Aktiengesellschaft Piperazine derivatives for binding and imaging amyloid plaques and their use
US9101612B2 (en) 2010-02-11 2015-08-11 Northwestern University Secondary structure stabilized NMDA receptor modulators and uses thereof
US9624170B2 (en) * 2013-12-26 2017-04-18 Takeda Pharmaceutical Company Limited 4-(piperrazin-1-yl)-pyrrolidin-2-one compounds as monoacylglycerol lipase (MAGL) inhibitors
US9221796B2 (en) * 2014-01-09 2015-12-29 Bristol-Myers Squibb Company Selective NR2B antagonists
US9187506B2 (en) * 2014-01-09 2015-11-17 Bristol-Myers Squibb Company (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one and its prodrugs for the treatment of psychiatric disorders
AU2016340239A1 (en) * 2015-10-14 2018-05-31 Bristol-Myers Squibb Company Selective NR2B antagonists

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