JP2012197278A5 - - Google Patents
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- JP2012197278A5 JP2012197278A5 JP2012091882A JP2012091882A JP2012197278A5 JP 2012197278 A5 JP2012197278 A5 JP 2012197278A5 JP 2012091882 A JP2012091882 A JP 2012091882A JP 2012091882 A JP2012091882 A JP 2012091882A JP 2012197278 A5 JP2012197278 A5 JP 2012197278A5
- Authority
- JP
- Japan
- Prior art keywords
- cdr
- antigen
- binding portion
- tumor cells
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000427 antigen Substances 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 210000004881 tumor cell Anatomy 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 2
- 102100041003 Glutamate carboxypeptidase 2 Human genes 0.000 claims 1
- 101000892862 Homo sapiens Glutamate carboxypeptidase 2 Proteins 0.000 claims 1
- 230000010782 T cell mediated cytotoxicity Effects 0.000 claims 1
- 108091008874 T cell receptors Proteins 0.000 claims 1
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 1
- 230000009089 cytolysis Effects 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 210000002307 prostate Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05011536.9 | 2005-05-27 | ||
| EP05011536A EP1726650A1 (en) | 2005-05-27 | 2005-05-27 | Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008512701A Division JP5038297B2 (ja) | 2005-05-27 | 2006-03-02 | 細胞表面の前立腺特異的膜抗原に対するモノクローナル抗体および単鎖抗体フラグメント |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014017392A Division JP6110321B2 (ja) | 2005-05-27 | 2014-01-31 | 細胞表面の前立腺特異的膜抗原に対するモノクローナル抗体および単鎖抗体フラグメント |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012197278A JP2012197278A (ja) | 2012-10-18 |
| JP2012197278A5 true JP2012197278A5 (cg-RX-API-DMAC7.html) | 2013-12-05 |
| JP5524270B2 JP5524270B2 (ja) | 2014-06-18 |
Family
ID=34937022
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008512701A Active JP5038297B2 (ja) | 2005-05-27 | 2006-03-02 | 細胞表面の前立腺特異的膜抗原に対するモノクローナル抗体および単鎖抗体フラグメント |
| JP2012091882A Active JP5524270B2 (ja) | 2005-05-27 | 2012-04-13 | 細胞表面の前立腺特異的膜抗原に対するモノクローナル抗体および単鎖抗体フラグメント |
| JP2014017392A Active JP6110321B2 (ja) | 2005-05-27 | 2014-01-31 | 細胞表面の前立腺特異的膜抗原に対するモノクローナル抗体および単鎖抗体フラグメント |
| JP2016063219A Pending JP2016190839A (ja) | 2005-05-27 | 2016-03-28 | 細胞表面の前立腺特異的膜抗原に対するモノクローナル抗体および単鎖抗体フラグメント |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008512701A Active JP5038297B2 (ja) | 2005-05-27 | 2006-03-02 | 細胞表面の前立腺特異的膜抗原に対するモノクローナル抗体および単鎖抗体フラグメント |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014017392A Active JP6110321B2 (ja) | 2005-05-27 | 2014-01-31 | 細胞表面の前立腺特異的膜抗原に対するモノクローナル抗体および単鎖抗体フラグメント |
| JP2016063219A Pending JP2016190839A (ja) | 2005-05-27 | 2016-03-28 | 細胞表面の前立腺特異的膜抗原に対するモノクローナル抗体および単鎖抗体フラグメント |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US8198416B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP1726650A1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP5038297B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101233236B (cg-RX-API-DMAC7.html) |
| AT (1) | ATE505544T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2006251445B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2609682C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1111409T1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE602006021296D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1883698T4 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2362795T5 (cg-RX-API-DMAC7.html) |
| PL (1) | PL1883698T5 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1883698E (cg-RX-API-DMAC7.html) |
| RU (1) | RU2458073C2 (cg-RX-API-DMAC7.html) |
| SI (1) | SI1883698T2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006125481A1 (cg-RX-API-DMAC7.html) |
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| HRP20120709T1 (hr) * | 2005-02-18 | 2012-10-31 | Medarex, Inc. | Humano monoklonsko protutijelo za prostata-specifiäśni membranski antigen (psma) |
| WO2006089231A2 (en) * | 2005-02-18 | 2006-08-24 | Medarex, Inc. | Monoclonal antibodies against prostate specific membrane antigen (psma) lacking in fucosyl residues |
| JP2008535865A (ja) * | 2005-04-08 | 2008-09-04 | サイトジェン コーポレーション | 抗ｐｓｍａコンジュゲート抗体 |
| EP1726650A1 (en) | 2005-05-27 | 2006-11-29 | Universitätsklinikum Freiburg | Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen |
| JP2008546792A (ja) * | 2005-06-20 | 2008-12-25 | ピーエスエムエー ディベロップメント カンパニー，エルエルシー | Ｐｓｍａ抗体薬物複合体 |
-
2005
- 2005-05-27 EP EP05011536A patent/EP1726650A1/en not_active Withdrawn
-
2006
- 2006-03-02 DK DK06707388.2T patent/DK1883698T4/en active
- 2006-03-02 CN CN2006800275807A patent/CN101233236B/zh active Active
- 2006-03-02 EP EP11151622A patent/EP2363486A1/en not_active Ceased
- 2006-03-02 AT AT06707388T patent/ATE505544T1/de active
- 2006-03-02 SI SI200630996T patent/SI1883698T2/sl unknown
- 2006-03-02 PT PT06707388T patent/PT1883698E/pt unknown
- 2006-03-02 RU RU2007147596/10A patent/RU2458073C2/ru active
- 2006-03-02 PL PL06707388T patent/PL1883698T5/pl unknown
- 2006-03-02 JP JP2008512701A patent/JP5038297B2/ja active Active
- 2006-03-02 EP EP06707388.2A patent/EP1883698B2/en active Active
- 2006-03-02 DE DE602006021296T patent/DE602006021296D1/de active Active
- 2006-03-02 WO PCT/EP2006/001917 patent/WO2006125481A1/en not_active Ceased
- 2006-03-02 AU AU2006251445A patent/AU2006251445B2/en active Active
- 2006-03-02 ES ES06707388.2T patent/ES2362795T5/es active Active
- 2006-03-02 US US11/915,454 patent/US8198416B2/en active Active
- 2006-03-02 CA CA2609682A patent/CA2609682C/en active Active
-
2011
- 2011-05-04 CY CY20111100431T patent/CY1111409T1/el unknown
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2012
- 2012-04-13 JP JP2012091882A patent/JP5524270B2/ja active Active
- 2012-05-08 US US13/466,286 patent/US8632777B2/en active Active
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2013
- 2013-12-13 US US14/105,808 patent/US9238694B2/en active Active
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2014
- 2014-01-31 JP JP2014017392A patent/JP6110321B2/ja active Active
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2016
- 2016-03-28 JP JP2016063219A patent/JP2016190839A/ja active Pending
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