JP2011529492A5 - - Google Patents
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- Publication number
- JP2011529492A5 JP2011529492A5 JP2011521085A JP2011521085A JP2011529492A5 JP 2011529492 A5 JP2011529492 A5 JP 2011529492A5 JP 2011521085 A JP2011521085 A JP 2011521085A JP 2011521085 A JP2011521085 A JP 2011521085A JP 2011529492 A5 JP2011529492 A5 JP 2011529492A5
- Authority
- JP
- Japan
- Prior art keywords
- fibrosis
- cancer
- therapeutic agent
- pancreatic
- liver
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010016654 Fibrosis Diseases 0.000 claims 5
- 230000004761 fibrosis Effects 0.000 claims 4
- 208000019425 cirrhosis of liver Diseases 0.000 claims 2
- 210000001260 vocal cord Anatomy 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 201000009794 Idiopathic Pulmonary Fibrosis Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010033645 Pancreatitis Diseases 0.000 claims 1
- 206010034665 Peritoneal fibrosis Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 230000007882 cirrhosis Effects 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 208000036971 interstitial lung disease 2 Diseases 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 206010028537 myelofibrosis Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 208000003476 primary myelofibrosis Diseases 0.000 claims 1
- 208000005069 pulmonary fibrosis Diseases 0.000 claims 1
- 230000037390 scarring Effects 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 description 11
- 229940124597 therapeutic agent Drugs 0.000 description 11
- 108020004459 Small interfering RNA Proteins 0.000 description 5
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 4
- 108020004707 nucleic acids Proteins 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 150000007523 nucleic acids Chemical class 0.000 description 3
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- 102000001214 HSP47 Heat-Shock Proteins Human genes 0.000 description 2
- 108010055039 HSP47 Heat-Shock Proteins Proteins 0.000 description 2
- 108010006519 Molecular Chaperones Proteins 0.000 description 2
- 102000005431 Molecular Chaperones Human genes 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 230000008685 targeting Effects 0.000 description 2
- 108020004414 DNA Proteins 0.000 description 1
- 101000998548 Yersinia ruckeri Alkaline proteinase inhibitor Proteins 0.000 description 1
- 230000000692 anti-sense effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003475 metalloproteinase inhibitor Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8495508P | 2008-07-30 | 2008-07-30 | |
| US8497708P | 2008-07-30 | 2008-07-30 | |
| US8496808P | 2008-07-30 | 2008-07-30 | |
| US8493908P | 2008-07-30 | 2008-07-30 | |
| US8494708P | 2008-07-30 | 2008-07-30 | |
| US8496408P | 2008-07-30 | 2008-07-30 | |
| US61/084,968 | 2008-07-30 | ||
| US61/084,955 | 2008-07-30 | ||
| US61/084,977 | 2008-07-30 | ||
| US61/084,964 | 2008-07-30 | ||
| US61/084,947 | 2008-07-30 | ||
| US61/084,939 | 2008-07-30 | ||
| PCT/US2008/076295 WO2010014117A1 (en) | 2008-07-30 | 2008-09-12 | Drug carriers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014019952A Division JP2014129364A (ja) | 2008-07-30 | 2014-02-05 | 薬物担体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011529492A JP2011529492A (ja) | 2011-12-08 |
| JP2011529492A5 true JP2011529492A5 (https=) | 2012-03-22 |
Family
ID=40627040
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011521085A Pending JP2011529492A (ja) | 2008-07-30 | 2008-09-12 | 薬物担体 |
| JP2014019952A Pending JP2014129364A (ja) | 2008-07-30 | 2014-02-05 | 薬物担体 |
| JP2015228674A Pending JP2016104732A (ja) | 2008-07-30 | 2015-11-24 | 薬物担体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014019952A Pending JP2014129364A (ja) | 2008-07-30 | 2014-02-05 | 薬物担体 |
| JP2015228674A Pending JP2016104732A (ja) | 2008-07-30 | 2015-11-24 | 薬物担体 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20100028416A1 (https=) |
| EP (1) | EP2323693B1 (https=) |
| JP (3) | JP2011529492A (https=) |
| KR (2) | KR20140065017A (https=) |
| CN (1) | CN102159247A (https=) |
| AU (1) | AU2008359989A1 (https=) |
| CA (1) | CA2732412C (https=) |
| ES (1) | ES2657214T3 (https=) |
| RU (2) | RU2505315C2 (https=) |
| TW (1) | TW201004646A (https=) |
| WO (1) | WO2010014117A1 (https=) |
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| US7358223B2 (en) | 2004-10-04 | 2008-04-15 | Nitto Denko Corporation | Biodegradable cationic polymers |
| US9393315B2 (en) | 2011-06-08 | 2016-07-19 | Nitto Denko Corporation | Compounds for targeting drug delivery and enhancing siRNA activity |
| JP2009221164A (ja) * | 2008-03-17 | 2009-10-01 | Nitto Denko Corp | 肺線維症処置剤 |
| US20120269886A1 (en) | 2004-12-22 | 2012-10-25 | Nitto Denko Corporation | Therapeutic agent for pulmonary fibrosis |
| HUE056941T2 (hu) | 2004-12-22 | 2022-04-28 | Nitto Denko Corp | Gyógyszerhordozó és gyógyszerhordozó kit fibrózis gátlására |
| JP5342834B2 (ja) * | 2008-09-05 | 2013-11-13 | 日東電工株式会社 | 骨髄線維症処置剤 |
| US9572886B2 (en) * | 2005-12-22 | 2017-02-21 | Nitto Denko Corporation | Agent for treating myelofibrosis |
| TWI407971B (zh) | 2007-03-30 | 2013-09-11 | 日東電工股份有限公司 | Cancer cells and tumor-related fibroblasts |
| US20080312174A1 (en) * | 2007-06-05 | 2008-12-18 | Nitto Denko Corporation | Water soluble crosslinked polymers |
| CN101970012A (zh) | 2007-09-14 | 2011-02-09 | 日东电工株式会社 | 药物载体 |
| KR20160095209A (ko) * | 2008-09-12 | 2016-08-10 | 닛토덴코 가부시키가이샤 | 섬유증 질환의 조영제 |
| WO2011072082A2 (en) * | 2009-12-09 | 2011-06-16 | Nitto Denko Corporation | Modulation of hsp47 expression |
| RU2635460C2 (ru) * | 2010-06-17 | 2017-11-13 | Нитто Денко Корпорейшн | Средство для лечения фиброза почек |
| JP5950428B2 (ja) | 2010-08-05 | 2016-07-13 | 日東電工株式会社 | 線維化組織から正常組織を再生するための組成物 |
| CN102652835A (zh) * | 2010-12-10 | 2012-09-05 | 邹长坪 | 缓释高分子维甲酸 |
| US9011903B2 (en) | 2011-06-08 | 2015-04-21 | Nitto Denko Corporation | Cationic lipids for therapeutic agent delivery formulations |
| TWI658830B (zh) | 2011-06-08 | 2019-05-11 | 日東電工股份有限公司 | Ｈｓｐ47表現調控強化用類視色素脂質體 |
| US10196637B2 (en) | 2011-06-08 | 2019-02-05 | Nitto Denko Corporation | Retinoid-lipid drug carrier |
| EP2718261B1 (en) * | 2011-06-08 | 2016-02-24 | Nitto Denko Corporation | Compounds for targeting drug delivery and enhancing sirna activity |
| ES2708932T3 (es) | 2011-06-21 | 2019-04-12 | Nitto Denko Corp | Agente inductor de apoptosis |
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| RU2575925C1 (ru) * | 2014-11-06 | 2016-02-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет тонких химических технологий имени М.В. Ломоносова" (МИТХТ им. М.В. Ломоносова) | Тетравалентные неогликоконъюгаты с углеводным разветвляющим ядром и способ их получения |
| US10264976B2 (en) * | 2014-12-26 | 2019-04-23 | The University Of Akron | Biocompatible flavonoid compounds for organelle and cell imaging |
| TW201707725A (zh) | 2015-08-18 | 2017-03-01 | 美國馬友醫藥教育研究基金會 | 載體－抗體組合物及其製造及使用方法 |
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| US10618969B2 (en) | 2016-04-06 | 2020-04-14 | Mayo Foundation For Medical Education And Research | Carrier-binding agent compositions and methods of making and using the same |
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| RU2703624C2 (ru) * | 2017-11-10 | 2019-10-21 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Коаксиальные регулярные нано-мезоструктуры, способ их получения и способ получения микрокапсул из этих структур |
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| WO2021053163A1 (en) | 2019-09-19 | 2021-03-25 | Danmarks Tekniske Universitet | Immune stimulating micelle composition |
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| US7304045B2 (en) * | 2004-10-05 | 2007-12-04 | Hsing-Wen Sung | Nanoparticles for targeting hepatoma cells |
| HUE056941T2 (hu) * | 2004-12-22 | 2022-04-28 | Nitto Denko Corp | Gyógyszerhordozó és gyógyszerhordozó kit fibrózis gátlására |
| CA2631704A1 (en) * | 2005-12-05 | 2007-06-14 | Nitto Denko Corporation | Polyglutamate-amino acid conjugates and methods |
| JP5342834B2 (ja) * | 2008-09-05 | 2013-11-13 | 日東電工株式会社 | 骨髄線維症処置剤 |
| US7700541B2 (en) * | 2006-04-06 | 2010-04-20 | Nitto Denko Corporation | Biodegradable cationic polymers |
| CN101970012A (zh) * | 2007-09-14 | 2011-02-09 | 日东电工株式会社 | 药物载体 |
-
2008
- 2008-09-12 ES ES08822306.0T patent/ES2657214T3/es active Active
- 2008-09-12 RU RU2011107076/15A patent/RU2505315C2/ru not_active IP Right Cessation
- 2008-09-12 CN CN2008801311871A patent/CN102159247A/zh active Pending
- 2008-09-12 WO PCT/US2008/076295 patent/WO2010014117A1/en not_active Ceased
- 2008-09-12 US US12/210,125 patent/US20100028416A1/en not_active Abandoned
- 2008-09-12 JP JP2011521085A patent/JP2011529492A/ja active Pending
- 2008-09-12 AU AU2008359989A patent/AU2008359989A1/en not_active Abandoned
- 2008-09-12 TW TW097135220A patent/TW201004646A/zh unknown
- 2008-09-12 KR KR1020147011804A patent/KR20140065017A/ko not_active Ceased
- 2008-09-12 CA CA2732412A patent/CA2732412C/en not_active Expired - Fee Related
- 2008-09-12 KR KR1020117004847A patent/KR20110051214A/ko not_active Ceased
- 2008-09-12 EP EP08822306.0A patent/EP2323693B1/en not_active Not-in-force
-
2013
- 2013-10-17 RU RU2013146387/15A patent/RU2013146387A/ru not_active Application Discontinuation
-
2014
- 2014-01-29 US US14/167,223 patent/US20140212474A1/en not_active Abandoned
- 2014-02-05 JP JP2014019952A patent/JP2014129364A/ja active Pending
-
2015
- 2015-11-24 JP JP2015228674A patent/JP2016104732A/ja active Pending
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