JP2011529329A5 - - Google Patents
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- Publication number
- JP2011529329A5 JP2011529329A5 JP2010506476A JP2010506476A JP2011529329A5 JP 2011529329 A5 JP2011529329 A5 JP 2011529329A5 JP 2010506476 A JP2010506476 A JP 2010506476A JP 2010506476 A JP2010506476 A JP 2010506476A JP 2011529329 A5 JP2011529329 A5 JP 2011529329A5
- Authority
- JP
- Japan
- Prior art keywords
- oct3
- nucleic acids
- acids encoding
- klf4
- nuclear reprogramming
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8484208P | 2008-07-30 | 2008-07-30 | |
| US61/084,842 | 2008-07-30 | ||
| US14117708P | 2008-12-29 | 2008-12-29 | |
| US61/141,177 | 2008-12-29 | ||
| US20393108P | 2008-12-30 | 2008-12-30 | |
| US61/203,931 | 2008-12-30 | ||
| PCT/JP2009/063906 WO2010013845A1 (en) | 2008-07-30 | 2009-07-30 | Method of efficiently establishing induced pluripotent stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011529329A JP2011529329A (ja) | 2011-12-08 |
| JP2011529329A5 true JP2011529329A5 (https=) | 2012-08-23 |
| JP5562231B2 JP5562231B2 (ja) | 2014-07-30 |
Family
ID=41610532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010506476A Active JP5562231B2 (ja) | 2008-07-30 | 2009-07-30 | 効率的な人工多能性幹細胞の樹立方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9528092B2 (https=) |
| EP (1) | EP2307539B1 (https=) |
| JP (1) | JP5562231B2 (https=) |
| KR (1) | KR101685209B1 (https=) |
| CN (2) | CN101848994A (https=) |
| CA (1) | CA2697621C (https=) |
| WO (1) | WO2010013845A1 (https=) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010042490A1 (en) * | 2008-10-06 | 2010-04-15 | Boston Medical Center Corporation | A single lentiviral vector system for induced pluripotent (ips) stem cells derivation |
| US8470308B2 (en) * | 2009-01-03 | 2013-06-25 | Ray C. Wasielewski | Enhanced medical implant comprising disrupted tooth pulp and tooth particles |
| US10328103B2 (en) | 2009-01-03 | 2019-06-25 | Ray C. Wasielewski | Medical treatment composition comprising mammalian dental pulp stem cells |
| JP5637354B2 (ja) * | 2009-03-30 | 2014-12-10 | 独立行政法人産業技術総合研究所 | 精製転写因子の調製法と細胞導入技術 |
| KR101774206B1 (ko) | 2009-08-07 | 2017-09-04 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 유도된 다능성 줄기 세포의 효율적인 확립 방법 |
| KR20120061053A (ko) | 2009-08-27 | 2012-06-12 | 시냅틱 리서치, 엘엘씨 | 유도 만능 줄기(ｉＰＳ) 세포 또는 조직 특이적 세포를 생성하기 위한 신규한 단백질 전달 시스템 |
| CN102803476A (zh) * | 2009-09-14 | 2012-11-28 | 程临钊 | 血细胞重编程产生多潜能干细胞和多功能干细胞 |
| US20120276070A1 (en) * | 2009-11-17 | 2012-11-01 | Vitro Diagnositics, Inc. | Induced Pluripotent Stem Cells and Related Methods |
| JP5984217B2 (ja) * | 2010-06-15 | 2016-09-06 | セルラー ダイナミクス インターナショナル， インコーポレイテッド | 少量の末梢血からの人工多能性幹細胞の作製 |
| CA2802525C (en) * | 2010-06-18 | 2021-06-22 | Cellular Dynamics International, Inc. | Cardiomyocyte medium with dialyzed serum |
| JP6029137B2 (ja) | 2010-12-03 | 2016-11-24 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| WO2012087965A2 (en) | 2010-12-22 | 2012-06-28 | Fate Therapauetics, Inc. | Cell culture platform for single cell sorting and enhanced reprogramming of ipscs |
| CA2843234C (en) | 2011-07-25 | 2019-08-13 | Kyoto University | Method for screening induced pluripotent stem cells |
| KR102031386B1 (ko) * | 2011-10-03 | 2019-10-11 | 닛산 가가쿠 가부시키가이샤 | 다능성 간세포로부터의 거핵구 및/또는 혈소판의 제조 방법 |
| WO2013058403A1 (ja) | 2011-10-21 | 2013-04-25 | 国立大学法人京都大学 | 層流による多能性維持単一分散細胞培養法 |
| US20140329317A1 (en) | 2011-11-25 | 2014-11-06 | Kyoto University | Method for culturing pluripotent stem cell |
| KR101930718B1 (ko) | 2012-03-28 | 2018-12-19 | 가부시키가이샤 쿠오리맨 앤 코. | 불사화 줄기세포 및 그 생산물을 유효 성분으로 하는 의약 조성물 및 의약 제제 |
| ES2725827T3 (es) | 2012-05-23 | 2019-09-27 | Univ Kyoto | Método altamente eficiente para establecer una célula madre pluripotencial artificial |
| US20150133467A1 (en) * | 2012-06-06 | 2015-05-14 | Kyoto University | Screening method, protein instability and/or stability inducers, and protein activity assessment |
| GB2516196B (en) | 2013-01-25 | 2015-09-09 | Xcell Biosciences Inc | Methods, compositions, kits, and systems for selective enrichment of target cells |
| US20160002599A1 (en) | 2013-02-08 | 2016-01-07 | Kyoto University | Production methods for megakaryocytes and platelets |
| US9738861B2 (en) | 2013-03-06 | 2017-08-22 | Kyoto University | Culture system for pluripotent stem cells and method for subculturing pluripotent stem cells |
| US9790468B2 (en) | 2013-03-15 | 2017-10-17 | Avita Iinternational Ltd. | Multifunctional immature dental pulp stem cells and therapeutic applications |
| US10519421B2 (en) | 2013-03-21 | 2019-12-31 | Kyoto University | Induction of motor neurons from pluripotent stem cells |
| WO2014157257A1 (ja) | 2013-03-25 | 2014-10-02 | 公益財団法人先端医療振興財団 | 細胞の選別方法 |
| JP6461787B2 (ja) | 2013-04-12 | 2019-01-30 | 国立大学法人京都大学 | 肺胞上皮前駆細胞の誘導方法 |
| US9822342B2 (en) | 2013-05-14 | 2017-11-21 | Kyoto University | Method of efficiently inducing cardiomyocytes |
| WO2015020113A1 (ja) | 2013-08-07 | 2015-02-12 | 国立大学法人京都大学 | 膵ホルモン産生細胞の製造法 |
| AU2014316100B2 (en) | 2013-09-05 | 2020-11-05 | Eisai R&D Management Co., Ltd. | New method for inducing dopamine-producing neural precursor cells |
| EP3064577B1 (en) | 2013-11-01 | 2020-09-09 | Kyoto University | Novel chondrocyte induction method |
| FR3016372B1 (fr) * | 2014-01-13 | 2018-01-19 | Centre Leon Berard | Procede de preparation de cellules pluripotentes induites |
| CN106102754B (zh) * | 2014-01-24 | 2020-04-17 | 石匠株式会社 | 癌治疗用医药组合物以及将该组合物作为有效成分的癌治疗用医药制剂 |
| CN104894060B (zh) * | 2014-03-03 | 2018-11-06 | 中国科学院上海生命科学研究院 | 诱导体细胞转分化为神经干细胞的方法及其应用 |
| SG11201606934SA (en) | 2014-03-04 | 2016-09-29 | Fate Therapeutics Inc | Improved reprogramming methods and cell culture platforms |
| KR102654784B1 (ko) | 2014-07-18 | 2024-04-04 | 사이아스 가부시키가이샤 | 다능성 줄기세포로부터 세포-기반 면역요법용 t 세포를 유도하는 방법 |
| WO2017017686A1 (en) | 2015-07-29 | 2017-02-02 | Hadasit Medical Research Services And Development Ltd. | Large scale production of retinal pigment epithelial cells |
| SG10202111851YA (en) | 2015-10-16 | 2021-12-30 | Fate Therapeutics Inc | Platform for the Induction & Maintenance of Ground State Pluripotency |
| CA3021628A1 (en) | 2016-04-22 | 2017-10-26 | Kyoto University | Method for producing dopamine-producing neural precursor cells |
| US20170369904A1 (en) * | 2016-06-22 | 2017-12-28 | Xcell Biosciences, Inc. | Methods for increasing cell culture transfection efficiency and cellular reprogramming |
| DK3537986T3 (da) | 2016-11-10 | 2025-07-21 | Viacyte Inc | Pdx1 pankreatiske endodermceller i celleleveringsanordning |
| US20210254013A1 (en) * | 2018-06-14 | 2021-08-19 | Figene, Llc | Use of fibroblasts and/or modified fibroblasts for three dimensional tissue printing |
| EP3824912A4 (en) | 2018-07-19 | 2022-04-20 | Kyoto University | PLATEFORM CARTILAGE DERIVED FROM PLURIPOTENTS STEM CELLS AND METHODS FOR PRODUCTION OF PLATEFORM CARTILAGE |
| WO2020022261A1 (ja) | 2018-07-23 | 2020-01-30 | 国立大学法人京都大学 | 新規腎前駆細胞マーカーおよびそれを利用した腎前駆細胞の濃縮方法 |
| JP7224001B2 (ja) | 2018-12-21 | 2023-02-17 | 国立大学法人京都大学 | ルブリシン局在軟骨様組織、その製造方法及びそれを含む関節軟骨損傷治療用組成物 |
| US20220313734A1 (en) * | 2019-05-09 | 2022-10-06 | Figene, Llc | Fibroblast generated patient-specific vaccines |
| CN114207118A (zh) | 2019-05-14 | 2022-03-18 | 阿利夫农场公司 | 多能细胞聚集体及其用途 |
| JP7058431B2 (ja) | 2019-12-12 | 2022-04-22 | 国立大学法人千葉大学 | 巨核球および血小板を含む凍結乾燥製剤 |
| US20230256024A1 (en) | 2020-07-13 | 2023-08-17 | Kyoto University | Skeletal muscle precursor cells and method for purifying same, composition for treating myogenic diseases, and method for producing cell group containing skeletal muscle precursor cells |
| CN116134130A (zh) | 2020-07-20 | 2023-05-16 | 学校法人爱知医科大学 | 多能细胞的未分化维持培养用组合物、多能细胞的未分化维持培养用培养基、多能细胞的未分化状态下的维持培养方法、和多能细胞的制造方法 |
| EP4477746A4 (en) | 2022-02-09 | 2026-02-18 | Racthera Co Ltd | METHOD FOR EVALUATING THE DIFFERENTIATION POTENTIAL OF CELLS IN A CULTURE BROTH IN THE DIFFERENCE OF MULTIPOTENTED STEM CELLS INTO NEURAL CELLS OF THE MENSCEPHAL FLOOR PLAQUE REGION |
| WO2024248017A1 (ja) | 2023-05-29 | 2024-12-05 | 国立研究開発法人理化学研究所 | 心筋細胞を成熟させる方法及び成熟した心筋細胞の製造方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU729377B2 (en) | 1997-10-23 | 2001-02-01 | Asterias Biotherapeutics, Inc. | Methods and materials for the growth of primate-derived primordial stem cells in feeder-free culture |
| US20020090722A1 (en) * | 2000-06-15 | 2002-07-11 | Tanja Dominko | Pluripotent mammalian cells |
| ES2705683T3 (es) | 2002-12-16 | 2019-03-26 | Technion Res & Dev Foundation | Medio de cultivo de células madre pluripotentes |
| US20040224401A1 (en) | 2003-03-28 | 2004-11-11 | Ludwig Tenneille E. | Physiochemical culture conditions for embryonic stem cells |
| AU2005282414C1 (en) | 2004-09-08 | 2011-04-07 | Wisconsin Alumni Research Foundation | Culturing human embryonic stem cells |
| US20060275899A1 (en) | 2004-12-30 | 2006-12-07 | Stemlifeline, Inc. | Methods and compositions relating to embryonic stem cell lines |
| BRPI0619794B8 (pt) | 2005-12-13 | 2022-06-14 | Univ Kyoto | Uso de um fator de reprogramação, agente para a preparação de uma célula-tronco pluripotente induzida a partir de uma célula somática e métodos para preparar uma célula- tronco pluripotente induzida método e para preparar uma célula somática e uso de células-tronco pluripotentes induzidas |
| US20090227032A1 (en) | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| CN101605885B (zh) | 2007-01-04 | 2013-03-27 | 卡尔·特吕格瓦松 | 能够使多能干细胞增殖的组合物及方法 |
| DK3399025T3 (da) | 2007-03-23 | 2025-06-16 | Wisconsin Alumni Res Found | Omprogrammering af somatiske celler |
| WO2009032456A2 (en) | 2007-08-01 | 2009-03-12 | Primegen Biotech Llc | Non-viral delivery of transcription factors that reprogram human somatic cells into a stem cell-like state |
| WO2009073523A2 (en) | 2007-11-29 | 2009-06-11 | Children's Hospital Of Orange County | De-differentiation of human cells |
| US9290740B2 (en) | 2008-03-07 | 2016-03-22 | Worcester Polytechnic Institute | Use of basic fibroblast growth factor in the de-differentiation of animal connective tissue cells |
| SG10201400329YA (en) | 2008-05-02 | 2014-05-29 | Univ Kyoto | Method of nuclear reprogramming |
| WO2009142717A2 (en) * | 2008-05-19 | 2009-11-26 | President And Fellows Of Harvard College | Methods and products for dedifferentiation of cells |
| CA2695590C (en) | 2008-06-27 | 2018-01-09 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| US20110231944A1 (en) | 2008-09-04 | 2011-09-22 | Riken | B cell-derived ips cells and application thereof |
| JP5652783B2 (ja) | 2008-09-08 | 2015-01-14 | 独立行政法人理化学研究所 | ＮＫＴ細胞由来ｉＰＳ細胞およびそれ由来のＮＫＴ細胞 |
| CN101492676B (zh) * | 2008-09-16 | 2011-02-16 | 中国科学院广州生物医药与健康研究院 | 用脑膜细胞生成诱导的多能性干细胞的方法及其用途 |
| KR101774206B1 (ko) | 2009-08-07 | 2017-09-04 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 유도된 다능성 줄기 세포의 효율적인 확립 방법 |
-
2009
- 2009-07-30 WO PCT/JP2009/063906 patent/WO2010013845A1/en not_active Ceased
- 2009-07-30 US US12/672,222 patent/US9528092B2/en active Active
- 2009-07-30 JP JP2010506476A patent/JP5562231B2/ja active Active
- 2009-07-30 CN CN200980100065A patent/CN101848994A/zh active Pending
- 2009-07-30 EP EP09803075.2A patent/EP2307539B1/en active Active
- 2009-07-30 CA CA2697621A patent/CA2697621C/en active Active
- 2009-07-30 KR KR1020107002641A patent/KR101685209B1/ko active Active
- 2009-07-30 CN CN201611216942.9A patent/CN107012123A/zh active Pending
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