JP2011527579A5 - - Google Patents

Info

Publication number

JP2011527579A5

JP2011527579A5 JP2011517571A JP2011517571A JP2011527579A5 JP 2011527579 A5 JP2011527579 A5 JP 2011527579A5 JP 2011517571 A JP2011517571 A JP 2011517571A JP 2011517571 A JP2011517571 A JP 2011517571A JP 2011527579 A5 JP2011527579 A5 JP 2011527579A5

Authority

JP

Japan

Prior art keywords

disease

seq

binding protein

antibody

syndrome

Prior art date

2009-07-08

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 108091008324 binding proteins Proteins 0.000 claims 55
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• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 33
• 239000012634 fragment Substances 0.000 claims 29
• 210000004027 cell Anatomy 0.000 claims 24
• 201000010099 disease Diseases 0.000 claims 21
• 239000003814 drug Substances 0.000 claims 21
• 208000011580 syndromic disease Diseases 0.000 claims 16
• -1 antibiotic Substances 0.000 claims 15
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• 208000029523 Interstitial Lung disease Diseases 0.000 claims 10
• 208000019693 Lung disease Diseases 0.000 claims 10
• 230000001154 acute effect Effects 0.000 claims 10
• 125000003275 alpha amino acid group Chemical group 0.000 claims 10
• 210000000056 organ Anatomy 0.000 claims 10
• 230000000694 effects Effects 0.000 claims 9
• 230000001684 chronic effect Effects 0.000 claims 8
• 239000000203 mixture Substances 0.000 claims 8
• CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 claims 7
• UHDGCWIWMRVCDJ-CCXZUQQUSA-N Cytarabine Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 UHDGCWIWMRVCDJ-CCXZUQQUSA-N 0.000 claims 7
• MWWSFMDVAYGXBV-RUELKSSGSA-N Doxorubicin hydrochloride Chemical compound Cl.O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 MWWSFMDVAYGXBV-RUELKSSGSA-N 0.000 claims 7
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• VSRXQHXAPYXROS-UHFFFAOYSA-N azanide;cyclobutane-1,1-dicarboxylic acid;platinum(2+) Chemical compound [NH2-].[NH2-].[Pt+2].OC(=O)C1(C(O)=O)CCC1 VSRXQHXAPYXROS-UHFFFAOYSA-N 0.000 claims 5
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• RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims 4
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• MWWSFMDVAYGXBV-FGBSZODSSA-N (7s,9s)-7-[(2r,4s,5r,6s)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7h-tetracene-5,12-dione;hydron;chloride Chemical compound Cl.O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@@H](O)[C@H](C)O1 MWWSFMDVAYGXBV-FGBSZODSSA-N 0.000 claims 3
• XAUDJQYHKZQPEU-KVQBGUIXSA-N 5-aza-2'-deoxycytidine Chemical compound O=C1N=C(N)N=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 XAUDJQYHKZQPEU-KVQBGUIXSA-N 0.000 claims 3
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• CMWTZPSULFXXJA-UHFFFAOYSA-N Naproxen Natural products C1=C(C(C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-UHFFFAOYSA-N 0.000 claims 3
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• RZEKVGVHFLEQIL-UHFFFAOYSA-N celecoxib Chemical compound C1=CC(C)=CC=C1C1=CC(C(F)(F)F)=NN1C1=CC=C(S(N)(=O)=O)C=C1 RZEKVGVHFLEQIL-UHFFFAOYSA-N 0.000 claims 3
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• DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 claims 3
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