JP2011520965A5 - - Google Patents
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- Publication number
- JP2011520965A5 JP2011520965A5 JP2011510594A JP2011510594A JP2011520965A5 JP 2011520965 A5 JP2011520965 A5 JP 2011520965A5 JP 2011510594 A JP2011510594 A JP 2011510594A JP 2011510594 A JP2011510594 A JP 2011510594A JP 2011520965 A5 JP2011520965 A5 JP 2011520965A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- sglt2
- sglt2 inhibitor
- uric acid
- hyperuricemia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCOc1ccc(Cc(c*(*[C@@]([C@]([C@](*)[C@@]2O)O)O[C@@]2NO)cc2)c2Cl)cc1 Chemical compound CCOc1ccc(Cc(c*(*[C@@]([C@]([C@](*)[C@@]2O)O)O[C@@]2NO)cc2)c2Cl)cc1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5535208P | 2008-05-22 | 2008-05-22 | |
| US61/055,352 | 2008-05-22 | ||
| PCT/US2009/044156 WO2009143020A1 (en) | 2008-05-22 | 2009-05-15 | Method for treating hyperuricemia employing an sglt2 inhibitor and composition containing same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014128550A Division JP2014205700A (ja) | 2008-05-22 | 2014-06-23 | Ｓｇｌｔ２阻害剤を使用する高尿酸血症の治療方法およびｓｇｌｔ２阻害剤を含有する組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011520965A JP2011520965A (ja) | 2011-07-21 |
| JP2011520965A5 true JP2011520965A5 (https=) | 2012-06-14 |
| JP5820269B2 JP5820269B2 (ja) | 2015-11-24 |
Family
ID=40810833
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011510594A Expired - Fee Related JP5820269B2 (ja) | 2008-05-22 | 2009-05-15 | Ｓｇｌｔ２阻害剤を使用する高尿酸血症の治療方法およびｓｇｌｔ２阻害剤を含有する組成物 |
| JP2014128550A Pending JP2014205700A (ja) | 2008-05-22 | 2014-06-23 | Ｓｇｌｔ２阻害剤を使用する高尿酸血症の治療方法およびｓｇｌｔ２阻害剤を含有する組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014128550A Pending JP2014205700A (ja) | 2008-05-22 | 2014-06-23 | Ｓｇｌｔ２阻害剤を使用する高尿酸血症の治療方法およびｓｇｌｔ２阻害剤を含有する組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8791077B2 (https=) |
| EP (2) | EP2668953A1 (https=) |
| JP (2) | JP5820269B2 (https=) |
| CN (1) | CN102105153B (https=) |
| BR (1) | BRPI0913129A2 (https=) |
| CA (1) | CA2725047A1 (https=) |
| ES (1) | ES2526930T3 (https=) |
| MX (1) | MX2010012656A (https=) |
| WO (1) | WO2009143020A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110009347A1 (en) | 2009-07-08 | 2011-01-13 | Yin Liang | Combination therapy for the treatment of diabetes |
| US8163704B2 (en) | 2009-10-20 | 2012-04-24 | Novartis Ag | Glycoside derivatives and uses thereof |
| SG186301A1 (en) | 2010-06-16 | 2013-02-28 | Takeda Pharmaceuticals Usa Inc | Novel modified release dosage forms of xanthine oxidoreductase inhibitor or xanthine oxidase inhibitors |
| US20140093563A1 (en) * | 2011-06-13 | 2014-04-03 | Ranbaxy Laboratories Limited | Febuxostat compositions |
| BR112014017902A2 (pt) * | 2012-01-27 | 2017-08-22 | Teijin Pharma Limited E National Univ Corporation Tottori Univ | Agente terapêutico ou profilático para doenças causadas por distúrbios do metabolismo de glicose |
| WO2014149789A1 (en) * | 2013-03-15 | 2014-09-25 | Janssen Pharmaceutica Nv | Combination of canagliflozin and probenecid for the treament of hyperuricemia |
| DK2981269T3 (da) | 2013-04-04 | 2023-10-23 | Boehringer Ingelheim Vetmedica Gmbh | Behandling af stofskifteforstyrrelser hos hestedyr |
| MX376097B (es) | 2013-12-17 | 2025-03-07 | Boehringer Ingelheim Vetmedica Gmbh | Inhibidores de sglt2 para usarse en el tratamiento o prevención de trastornos metabólicos en animales felinos. |
| CA2932674C (en) | 2014-01-23 | 2023-01-24 | Boehringer Ingelheim Vetmedica Gmbh | Treatment of metabolic disorders in canine animals |
| FI3721882T3 (fi) | 2014-04-01 | 2024-09-24 | Boehringer Ingelheim Vetmedica Gmbh | Aineenvaihduntahäiriöiden hoito hevoseläimissä |
| EP4403230A3 (en) | 2014-09-25 | 2025-01-08 | Boehringer Ingelheim Vetmedica GmbH | Combination treatment of sglt2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals |
| AU2016310535B2 (en) * | 2015-08-27 | 2021-08-19 | Boehringer Ingelheim Vetmedica Gmbh | Liquid pharmaceutical compositions comprising SGLT-2 inhibitors |
| KR101863604B1 (ko) * | 2016-04-08 | 2018-06-04 | 한국 한의학 연구원 | 익지 추출물을 유효성분으로 함유하는 고요산혈증 또는 고요산혈증 관련 대사 장애의 예방, 개선 또는 치료용 조성물 |
| WO2018167589A1 (en) | 2017-03-16 | 2018-09-20 | Inventia Healthcare Private Limited | Pharmaceutical composition comprising dapagliflozin |
| WO2019087239A1 (ja) * | 2017-10-30 | 2019-05-09 | 合同会社カルナヘルスサポート | 腎症治療剤 |
| WO2019092770A1 (ja) * | 2017-11-07 | 2019-05-16 | 合同会社カルナヘルスサポート | 網膜疾患治療剤 |
| MX2021003845A (es) * | 2018-10-01 | 2021-05-27 | Astrazeneca Ab | Composiciones para reducir el acido urico serico. |
| SG11202105743RA (en) * | 2018-12-06 | 2021-06-29 | Arthrosi Therapeutics Inc | Methods for treating or preventing gout or hyperuricemia |
| KR102946486B1 (ko) | 2018-12-06 | 2026-03-31 | 아쓰로시 테라퓨틱스, 인크. | 통풍 또는 고뇨산혈증의 치료 또는 예방을 위한 화합물의 결정형 |
| EP3934628A4 (en) * | 2019-03-03 | 2022-12-14 | Algatechnologies Ltd. | COMPOSITIONS CONTAINING ALGAE POWDER AND THEIR USES |
| JP6831961B2 (ja) * | 2019-10-23 | 2021-02-24 | 株式会社カルナヘルスサポート | 網膜疾患治療剤 |
| EP4064854A1 (en) | 2019-11-28 | 2022-10-05 | Boehringer Ingelheim Vetmedica GmbH | Use of sglt-2 inhibitors in the drying-off of non-human mammals |
| KR20230024354A (ko) * | 2020-06-10 | 2023-02-20 | 아쓰로시 테라퓨틱스, 인크. | 만성 신장 질환을 치료 또는 예방하는 방법 |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4346094A (en) * | 1980-09-22 | 1982-08-24 | Eli Lilly And Company | 3-Aryl-5-isothiazolecarboxylic acids and related compounds used to lower uric acid levels |
| CA2102591C (en) | 1992-11-12 | 2000-12-26 | Kenji Tsujihara | Hypoglycemic agent |
| US5830873A (en) | 1994-05-11 | 1998-11-03 | Tanabe Seiyaku Co., Ltd. | Propiophenone derivative and a process for preparing the same |
| JP2814950B2 (ja) | 1994-05-11 | 1998-10-27 | 田辺製薬株式会社 | 血糖降下剤 |
| JP3034192B2 (ja) | 1995-11-07 | 2000-04-17 | 田辺製薬株式会社 | プロピオフェノン誘導体およびその製法 |
| JP3006513B2 (ja) | 1995-11-07 | 2000-02-07 | 田辺製薬株式会社 | 医薬組成物 |
| JP3059088B2 (ja) | 1995-11-07 | 2000-07-04 | 田辺製薬株式会社 | プロピオフェノン誘導体およびその製法 |
| JP3065235B2 (ja) | 1995-11-07 | 2000-07-17 | 田辺製薬株式会社 | プロピオフェノン誘導体およびその製法 |
| AU719726B2 (en) | 1996-12-26 | 2000-05-18 | Tanabe Seiyaku Co., Ltd. | Propiophenone derivatives and process for preparing the same |
| JPH10245391A (ja) | 1997-03-03 | 1998-09-14 | Dainippon Ink & Chem Inc | ７−グリコシロキシベンゾピラン誘導体を有効成分とする糖尿病治療剤 |
| PH12000002657B1 (en) | 1999-10-12 | 2006-02-21 | Bristol Myers Squibb Co | C-aryl glucoside SGLT2 inhibitors |
| US6515117B2 (en) * | 1999-10-12 | 2003-02-04 | Bristol-Myers Squibb Company | C-aryl glucoside SGLT2 inhibitors and method |
| US6555519B2 (en) | 2000-03-30 | 2003-04-29 | Bristol-Myers Squibb Company | O-glucosylated benzamide SGLT2 inhibitors and method |
| US6683056B2 (en) | 2000-03-30 | 2004-01-27 | Bristol-Myers Squibb Company | O-aryl glucoside SGLT2 inhibitors and method |
| ATE455785T1 (de) | 2000-11-02 | 2010-02-15 | Ajinomoto Kk | Neue pyrazolderivate und diese enthaltende mittel gegen diabetes |
| CA2438593C (en) * | 2001-02-26 | 2010-09-21 | Kissei Pharmaceutical Co., Ltd. | Glucopyranosyloxypyrazole derivatives and medicinal use thereof |
| CA2438595C (en) | 2001-02-27 | 2011-08-09 | Kissei Pharmaceutical Co., Ltd. | Glucopyranosyloxypyrazole derivatives and medicinal use thereof |
| JP4590158B2 (ja) | 2001-04-04 | 2010-12-01 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | グルコース再吸収阻害剤およびレチノイド−ｘ受容体モジュレーターを含んで成る併用療法 |
| WO2002083066A2 (en) | 2001-04-11 | 2002-10-24 | Bristol-Myers Squibb Company | Amino acid complexes of c-aryl glucosides for treatment of diabetes and method |
| JP4292570B2 (ja) | 2001-04-27 | 2009-07-08 | 味の素株式会社 | Ｎ−置換ピラゾール−ｏ−グリコシド誘導体及びそれらを含有する糖尿病治療薬 |
| EP1404215B1 (en) | 2001-06-20 | 2007-08-15 | Purdue Research Foundation | Body-member-illuminating pressure cuff for use in optical noninvasive measurement of blood parameters |
| JP4490109B2 (ja) | 2002-03-22 | 2010-06-23 | キッセイ薬品工業株式会社 | グルコピラノシルオキシベンジルベンゼン誘導体の結晶 |
| ES2567571T3 (es) | 2003-03-14 | 2016-04-25 | Astellas Pharma Inc. | Derivados de C-glucósido y sales de los mismos |
| CN1761676A (zh) | 2003-04-01 | 2006-04-19 | 大正制药株式会社 | 杂芳基5－硫代－β－D－吡喃葡糖苷衍生物及含有该衍生物的糖尿病治疗药 |
| WO2004089966A1 (ja) * | 2003-04-01 | 2004-10-21 | Taisho Pharmaceutical Co., Ltd. | 選択的なヘテロアリール ５－チオ－β－Ｄ－アルドヘキソピラノシドの製造法 |
| JP2004359630A (ja) | 2003-06-06 | 2004-12-24 | Yamanouchi Pharmaceut Co Ltd | ジフルオロジフェニルメタン誘導体及びその塩 |
| US20050027128A1 (en) * | 2003-07-30 | 2005-02-03 | Robbins Timothy A. | Substituted thiazoles |
| UA86042C2 (en) | 2003-08-01 | 2009-03-25 | Янссен Фармацевтика Н.В. | Substituted indazole-o-glucosides |
| LT2896397T (lt) | 2003-08-01 | 2017-11-27 | Mitsubishi Tanabe Pharma Corporation | Nauji junginiai, turintys inhibitorinį aktyvumą prieš nuo natrio priklausomą gliukozės transporterį |
| US7375090B2 (en) | 2003-08-26 | 2008-05-20 | Boehringer Ingelheim International Gmbh | Glucopyranosyloxy-pyrazoles, pharmaceutical compositions containing these compounds, the use thereof and processed for the preparation thereof |
| ES2377937T3 (es) * | 2003-12-26 | 2012-04-03 | Kissei Pharmaceutical Co., Ltd. | Derivados de benzimidazol y usos médicos de los mismos |
| ATE557013T1 (de) | 2004-03-16 | 2012-05-15 | Boehringer Ingelheim Int | Glucopyranosyl-substituierte benzol-derivate, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung |
| WO2005095429A1 (ja) | 2004-03-31 | 2005-10-13 | Kissei Pharmaceutical Co., Ltd. | フェノール誘導体、それを含有する医薬組成物及びその医薬用途 |
| JP2005350375A (ja) | 2004-06-09 | 2005-12-22 | Kikkoman Corp | 血中尿酸値低下剤 |
| US7393836B2 (en) | 2004-07-06 | 2008-07-01 | Boehringer Ingelheim International Gmbh | D-xylopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture |
| DE102004034690A1 (de) | 2004-07-17 | 2006-02-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Methyliden-D-xylopyranosyl-und Oxo-D-xylopyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| TW200606129A (en) | 2004-07-26 | 2006-02-16 | Chugai Pharmaceutical Co Ltd | Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same |
| EP1773800A1 (de) | 2004-07-27 | 2007-04-18 | Boehringer Ingelheim International GmbH | D-glucopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung |
| WO2006018150A1 (de) | 2004-08-11 | 2006-02-23 | Boehringer Ingelheim International Gmbh | D-xylopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung |
| AR051446A1 (es) | 2004-09-23 | 2007-01-17 | Bristol Myers Squibb Co | Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2) |
| JP2006117651A (ja) | 2004-09-27 | 2006-05-11 | Taisho Pharmaceut Co Ltd | Ｓｇｌｔ２の活性阻害剤 |
| US20080139484A1 (en) | 2004-09-29 | 2008-06-12 | Kissei Pharmaceutical Co., Ltd. | 1(Beta-D-Glycopyranosyl)-3-Substituted Nitrogenous Heterocyclic Compound, Medicinal Composition Containing the Same, and Medicinal Use Thereof |
| DE102004048388A1 (de) | 2004-10-01 | 2006-04-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | D-Pyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| CN100457143C (zh) * | 2004-11-29 | 2009-02-04 | 成都华西天然药物有限公司 | 一种治疗痛风的药物 |
| DE102004058449A1 (de) | 2004-12-03 | 2006-06-14 | Merck Patent Gmbh | Tetrahydropyranderivate |
| TW200637839A (en) * | 2005-01-07 | 2006-11-01 | Taisho Pharmaceutical Co Ltd | 1-thio-d-glucitol derivatives |
| TW200637869A (en) | 2005-01-28 | 2006-11-01 | Chugai Pharmaceutical Co Ltd | The spiroketal derivatives and the use as therapeutical agent for diabetes of the same |
| CA2620566A1 (en) | 2005-08-30 | 2007-03-08 | Boehringer Ingelheim International Gmbh | Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture |
| WO2007093610A1 (en) | 2006-02-15 | 2007-08-23 | Boehringer Ingelheim International Gmbh | Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture |
| TW200812995A (en) | 2006-05-19 | 2008-03-16 | Taisho Pharmaceutical Co Ltd | C-phenyl glycitol compound |
| JP5230613B2 (ja) | 2006-05-23 | 2013-07-10 | テラコス・インコーポレイテッド | グルコース輸送体阻害剤およびその使用方法 |
| US7919598B2 (en) | 2006-06-28 | 2011-04-05 | Bristol-Myers Squibb Company | Crystal structures of SGLT2 inhibitors and processes for preparing same |
| AU2007316613B2 (en) * | 2006-11-09 | 2013-11-28 | Boehringer Ingelheim International Gmbh | Combination therapy with SGLT-2 inhibitors and their pharmaceutical compositions |
| AR065809A1 (es) * | 2007-03-22 | 2009-07-01 | Bristol Myers Squibb Co | Formulaciones farmaceuticas que contienen un inhibidor sglt2 |
| WO2009143021A1 (en) * | 2008-05-22 | 2009-11-26 | Bristol-Myers Squibb Company | Method for treating and preventing kidney stones employing an sglt2 inhibitor and composition containing same |
-
2009
- 2009-05-15 US US12/993,750 patent/US8791077B2/en not_active Expired - Fee Related
- 2009-05-15 CA CA2725047A patent/CA2725047A1/en not_active Abandoned
- 2009-05-15 ES ES09751249.5T patent/ES2526930T3/es active Active
- 2009-05-15 EP EP13181659.7A patent/EP2668953A1/en not_active Withdrawn
- 2009-05-15 JP JP2011510594A patent/JP5820269B2/ja not_active Expired - Fee Related
- 2009-05-15 MX MX2010012656A patent/MX2010012656A/es active IP Right Grant
- 2009-05-15 WO PCT/US2009/044156 patent/WO2009143020A1/en not_active Ceased
- 2009-05-15 CN CN200980128978.3A patent/CN102105153B/zh not_active Expired - Fee Related
- 2009-05-15 BR BRPI0913129A patent/BRPI0913129A2/pt not_active IP Right Cessation
- 2009-05-15 EP EP09751249.5A patent/EP2291189B1/en not_active Not-in-force
-
2014
- 2014-06-23 JP JP2014128550A patent/JP2014205700A/ja active Pending
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