CN102105153B - Sglt2抑制剂的医药用途和含该抑制剂的组合物 - Google Patents

Sglt2抑制剂的医药用途和含该抑制剂的组合物 Download PDF

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Publication number
CN102105153B
CN102105153B CN200980128978.3A CN200980128978A CN102105153B CN 102105153 B CN102105153 B CN 102105153B CN 200980128978 A CN200980128978 A CN 200980128978A CN 102105153 B CN102105153 B CN 102105153B
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China
Prior art keywords
inhibitor
sglt2
uric acid
hyperuricemia
dapagliflozin
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Expired - Fee Related
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CN200980128978.3A
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English (en)
Chinese (zh)
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CN102105153A (zh
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B·R·莱斯利
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AstraZeneca AB
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Bristol Myers Squibb Co
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
CN200980128978.3A 2008-05-22 2009-05-15 Sglt2抑制剂的医药用途和含该抑制剂的组合物 Expired - Fee Related CN102105153B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5535208P 2008-05-22 2008-05-22
US61/055352 2008-05-22
PCT/US2009/044156 WO2009143020A1 (en) 2008-05-22 2009-05-15 Method for treating hyperuricemia employing an sglt2 inhibitor and composition containing same

Publications (2)

Publication Number Publication Date
CN102105153A CN102105153A (zh) 2011-06-22
CN102105153B true CN102105153B (zh) 2014-03-05

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CN200980128978.3A Expired - Fee Related CN102105153B (zh) 2008-05-22 2009-05-15 Sglt2抑制剂的医药用途和含该抑制剂的组合物

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Country Link
US (1) US8791077B2 (https=)
EP (2) EP2291189B1 (https=)
JP (2) JP5820269B2 (https=)
CN (1) CN102105153B (https=)
BR (1) BRPI0913129A2 (https=)
CA (1) CA2725047A1 (https=)
ES (1) ES2526930T3 (https=)
MX (1) MX2010012656A (https=)
WO (1) WO2009143020A1 (https=)

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PT2981269T (pt) 2013-04-04 2023-10-10 Boehringer Ingelheim Vetmedica Gmbh Tratamento de distúrbios metabólicos em animais equinos
ES2969764T3 (es) 2013-12-17 2024-05-22 Boehringer Ingelheim Vetmedica Gmbh Un inhibidor de SGLT-2 para usar en el tratamiento de un trastorno metabólico en animales felinos
CN115671290A (zh) 2014-01-23 2023-02-03 勃林格殷格翰动物保健有限公司 犬科动物中代谢紊乱的治疗
WO2015150299A2 (en) 2014-04-01 2015-10-08 Boehringer Ingelheim Vetmedica Gmbh Treatment of metabolic disorders in equine animals
WO2016046150A1 (en) 2014-09-25 2016-03-31 Boehringer Ingelheim Vetmedica Gmbh Combination treatment of sglt2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals
KR102659761B1 (ko) * 2015-08-27 2024-04-24 베링거잉겔하임베트메디카게엠베하 Sglt-2 억제제를 포함하는 액상 약제학적 조성물
KR101863604B1 (ko) * 2016-04-08 2018-06-04 한국 한의학 연구원 익지 추출물을 유효성분으로 함유하는 고요산혈증 또는 고요산혈증 관련 대사 장애의 예방, 개선 또는 치료용 조성물
WO2018167589A1 (en) 2017-03-16 2018-09-20 Inventia Healthcare Private Limited Pharmaceutical composition comprising dapagliflozin
WO2019087239A1 (ja) * 2017-10-30 2019-05-09 合同会社カルナヘルスサポート 腎症治療剤
WO2019092770A1 (ja) * 2017-11-07 2019-05-16 合同会社カルナヘルスサポート 網膜疾患治療剤
US20210338648A1 (en) * 2018-10-01 2021-11-04 Astrazeneca Ab Methods and compositions for reducing serum uric acid
CA3121624A1 (en) * 2018-12-06 2020-06-11 Arthrosi Therapeutics, Inc. Methods for treating or preventing gout or hyperuricemia
US12145917B2 (en) 2018-12-06 2024-11-19 Arthrosi Therapeutics, Inc. Crystalline forms of a compound for treating or preventing gout or hyperuricemia
EP3934628A4 (en) * 2019-03-03 2022-12-14 Algatechnologies Ltd. COMPOSITIONS CONTAINING ALGAE POWDER AND THEIR USES
JP6831961B2 (ja) * 2019-10-23 2021-02-24 株式会社カルナヘルスサポート 網膜疾患治療剤
EP4064854A1 (en) 2019-11-28 2022-10-05 Boehringer Ingelheim Vetmedica GmbH Use of sglt-2 inhibitors in the drying-off of non-human mammals
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Also Published As

Publication number Publication date
JP2014205700A (ja) 2014-10-30
CN102105153A (zh) 2011-06-22
JP5820269B2 (ja) 2015-11-24
BRPI0913129A2 (pt) 2016-01-05
CA2725047A1 (en) 2009-11-26
JP2011520965A (ja) 2011-07-21
WO2009143020A1 (en) 2009-11-26
EP2668953A1 (en) 2013-12-04
MX2010012656A (es) 2010-12-20
US8791077B2 (en) 2014-07-29
ES2526930T3 (es) 2015-01-16
EP2291189B1 (en) 2014-10-01
US20110065658A1 (en) 2011-03-17
EP2291189A1 (en) 2011-03-09

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