JP2011513309A5 - - Google Patents

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Publication number
JP2011513309A5
JP2011513309A5 JP2010548747A JP2010548747A JP2011513309A5 JP 2011513309 A5 JP2011513309 A5 JP 2011513309A5 JP 2010548747 A JP2010548747 A JP 2010548747A JP 2010548747 A JP2010548747 A JP 2010548747A JP 2011513309 A5 JP2011513309 A5 JP 2011513309A5
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Japan
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disease
patient
deuterium
compound
pharmaceutically acceptable
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JP2010548747A
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English (en)
Japanese (ja)
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JP2011513309A (ja
JP5567503B2 (ja
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Priority claimed from PCT/US2009/001305 external-priority patent/WO2009108383A2/en
Publication of JP2011513309A publication Critical patent/JP2011513309A/ja
Publication of JP2011513309A5 publication Critical patent/JP2011513309A5/ja
Application granted granted Critical
Publication of JP5567503B2 publication Critical patent/JP5567503B2/ja
Expired - Fee Related legal-status Critical Current
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JP2010548747A 2008-02-29 2009-02-27 置換キサンチン誘導体 Expired - Fee Related JP5567503B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US6773608P 2008-02-29 2008-02-29
US61/067,736 2008-02-29
US13456808P 2008-07-11 2008-07-11
US61/134,568 2008-07-11
US19871508P 2008-11-07 2008-11-07
US61/198,715 2008-11-07
PCT/US2009/001305 WO2009108383A2 (en) 2008-02-29 2009-02-27 Substituted xanthine derivatives

Publications (3)

Publication Number Publication Date
JP2011513309A JP2011513309A (ja) 2011-04-28
JP2011513309A5 true JP2011513309A5 (cg-RX-API-DMAC7.html) 2012-04-12
JP5567503B2 JP5567503B2 (ja) 2014-08-06

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ID=40600003

Family Applications (2)

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JP2010548747A Expired - Fee Related JP5567503B2 (ja) 2008-02-29 2009-02-27 置換キサンチン誘導体
JP2010548745A Active JP5292413B2 (ja) 2008-02-29 2009-02-27 置換キサンチン誘導体

Family Applications After (1)

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JP2010548745A Active JP5292413B2 (ja) 2008-02-29 2009-02-27 置換キサンチン誘導体

Country Status (12)

Country Link
US (3) US20090239886A1 (cg-RX-API-DMAC7.html)
EP (3) EP2265612B1 (cg-RX-API-DMAC7.html)
JP (2) JP5567503B2 (cg-RX-API-DMAC7.html)
KR (1) KR20100121527A (cg-RX-API-DMAC7.html)
CN (1) CN101998957B (cg-RX-API-DMAC7.html)
AU (1) AU2009217680B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0908107A2 (cg-RX-API-DMAC7.html)
CA (1) CA2716788C (cg-RX-API-DMAC7.html)
EA (1) EA019088B1 (cg-RX-API-DMAC7.html)
MX (1) MX2010009300A (cg-RX-API-DMAC7.html)
WO (2) WO2009108383A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA201006104B (cg-RX-API-DMAC7.html)

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WO2009108383A2 (en) 2008-02-29 2009-09-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US8637466B2 (en) 2008-08-11 2014-01-28 Nektar Therapeutics Multi-arm polymeric alkanoate conjugates
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WO2010075086A2 (en) * 2008-12-15 2010-07-01 Auspex Pharmaceuticals, Inc. Pyrrolidinone inhibitors of pde-4
US20110053961A1 (en) * 2009-02-27 2011-03-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US8952016B2 (en) 2009-02-27 2015-02-10 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US8263601B2 (en) 2009-02-27 2012-09-11 Concert Pharmaceuticals, Inc. Deuterium substituted xanthine derivatives
US9260432B2 (en) 2009-09-02 2016-02-16 Concert Pharmaceuticals, Inc. Substituted derivatives of bicyclic [4.3.0] heteroaryl compounds
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US9074233B2 (en) 2010-09-01 2015-07-07 Concert Pharmaceuticals, Inc. Process for preparing an enantiomerically enriched, deuterated secondary alcohol from a corresponding ketone without reducing deuterium incorporation
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WO2012088445A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
JP6110846B2 (ja) * 2011-05-27 2017-04-05 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Ｃ型肝炎ウイルス阻害剤としての重水素が導入されたトリペプチド
US20140296263A1 (en) * 2011-07-19 2014-10-02 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
CA2869874A1 (en) * 2012-04-13 2013-10-17 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US20150087660A1 (en) * 2012-05-10 2015-03-26 Mahesh Kandula Compositions and methods for the treatment of chronic diseases and inflammatory disorders
KR20160117596A (ko) 2014-02-07 2016-10-10 오스펙스 파마슈티칼스, 인코포레이티드 신규 제약 제제
WO2015160913A1 (en) 2014-04-18 2015-10-22 Concert Pharmaceuticals, Inc. Methods of treating hyperglycemia
WO2015175008A1 (en) * 2014-05-14 2015-11-19 Concert Pharmaceuticals, Inc. Methods of treating chronic kidney disease characterized by macroalbuminuria
WO2017058881A1 (en) 2015-09-28 2017-04-06 The Trustees Of Columbia University In The City Of New York Use of pentoxifylline with immune checkpoint-blockade therapies for the treatment of melanoma
WO2017071606A1 (zh) * 2015-10-29 2017-05-04 南京明德新药研发股份有限公司 羟基嘌呤类化合物的医药用途

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