AU9084991A - Antifungal activity of and prevention of drug induced nephrotoxicity by methylxanthine analogues - Google Patents

Antifungal activity of and prevention of drug induced nephrotoxicity by methylxanthine analogues

Info

Publication number
AU9084991A
AU9084991A AU90849/91A AU9084991A AU9084991A AU 9084991 A AU9084991 A AU 9084991A AU 90849/91 A AU90849/91 A AU 90849/91A AU 9084991 A AU9084991 A AU 9084991A AU 9084991 A AU9084991 A AU 9084991A
Authority
AU
Australia
Prior art keywords
methylxanthine
analogues
prevention
antifungal activity
drug induced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU90849/91A
Inventor
Kurt L Berens
Lane J Brunner
Gabriel Lopez-Berestein
David R Luke
Kiumars Vadiei
Kishor Wasan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
University of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System filed Critical University of Texas System
Publication of AU9084991A publication Critical patent/AU9084991A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU90849/91A 1990-11-01 1991-11-01 Antifungal activity of and prevention of drug induced nephrotoxicity by methylxanthine analogues Abandoned AU9084991A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60815890A 1990-11-01 1990-11-01
US608158 1990-11-01

Publications (1)

Publication Number Publication Date
AU9084991A true AU9084991A (en) 1992-05-26

Family

ID=24435308

Family Applications (1)

Application Number Title Priority Date Filing Date
AU90849/91A Abandoned AU9084991A (en) 1990-11-01 1991-11-01 Antifungal activity of and prevention of drug induced nephrotoxicity by methylxanthine analogues

Country Status (2)

Country Link
AU (1) AU9084991A (en)
WO (1) WO1992007566A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4430127A1 (en) * 1994-08-25 1996-03-14 Hoechst Ag Combination preparation containing cyclosporin A or FK506 and a xanthine derivative
US5981536A (en) * 1996-07-31 1999-11-09 Hoechst Aktiengesellschaft Use of xanthine derivatives for the modulation of apoptosis
US5856330A (en) * 1996-07-31 1999-01-05 Hoechst Aktiengesellschaft Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin
US6294350B1 (en) * 1997-06-05 2001-09-25 Dalhousie University Methods for treating fibroproliferative diseases
ATE295172T1 (en) * 1998-02-27 2005-05-15 Daiichi Suntory Pharma Co Ltd PROPYLAXIS AND TREATMENT OF DRUG-INDUCED KIDNEY DISORDERS
SE0000234D0 (en) * 2000-01-26 2000-01-26 Kjell Grankvist Antifungal drug composition and drug delivery system
EP2265334A2 (en) 2008-02-29 2010-12-29 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US20110053961A1 (en) 2009-02-27 2011-03-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
US8952016B2 (en) 2009-02-27 2015-02-10 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
EP2611807A2 (en) 2010-09-01 2013-07-10 Concert Pharmaceuticals Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purine-2,6(3h,7h)dione
WO2013013052A1 (en) 2011-07-19 2013-01-24 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
IN2014DN08443A (en) 2012-04-13 2015-05-08 Concert Pharmaceuticals Inc
WO2013159006A1 (en) 2012-04-20 2013-10-24 Concert Pharmaceuticals, Inc. Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3817955A1 (en) * 1988-05-27 1989-11-30 Hoechst Ag MEDICINAL PRODUCT CONTAINING TNF INHIBITOR
EP0414175A3 (en) * 1989-08-22 1992-04-01 Hoechst Aktiengesellschaft Use of xanthine derivatives to reduce nephrotoxicity

Also Published As

Publication number Publication date
WO1992007566A3 (en) 1992-10-15
WO1992007566A2 (en) 1992-05-14

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