JP2011511075A5 - - Google Patents
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- Publication number
- JP2011511075A5 JP2011511075A5 JP2010545891A JP2010545891A JP2011511075A5 JP 2011511075 A5 JP2011511075 A5 JP 2011511075A5 JP 2010545891 A JP2010545891 A JP 2010545891A JP 2010545891 A JP2010545891 A JP 2010545891A JP 2011511075 A5 JP2011511075 A5 JP 2011511075A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- unsubstituted
- alkoxy
- phenyl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 Cc1c(CCN2CCOCC2)c2cc(**)ccc2[n]1C(c(cccc1Cl)c1Cl)=O Chemical compound Cc1c(CCN2CCOCC2)c2cc(**)ccc2[n]1C(c(cccc1Cl)c1Cl)=O 0.000 description 5
- JZCPYUJPEARBJL-UHFFFAOYSA-N Cc1c(-c(cc2)ccc2Cl)[n](-c(c(Cl)c2)ccc2Cl)nc1C(NN1CCCCC1)=O Chemical compound Cc1c(-c(cc2)ccc2Cl)[n](-c(c(Cl)c2)ccc2Cl)nc1C(NN1CCCCC1)=O JZCPYUJPEARBJL-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6508908P | 2008-02-08 | 2008-02-08 | |
| US61/065,089 | 2008-02-08 | ||
| PCT/US2009/000810 WO2009099670A2 (en) | 2008-02-08 | 2009-02-06 | Oligomer-cannabinoid conjugates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011511075A JP2011511075A (ja) | 2011-04-07 |
| JP2011511075A5 true JP2011511075A5 (enExample) | 2013-01-31 |
| JP5704925B2 JP5704925B2 (ja) | 2015-04-22 |
Family
ID=40602328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010545891A Expired - Fee Related JP5704925B2 (ja) | 2008-02-08 | 2009-02-06 | オリゴマー−カンナビノイドコンジュゲート |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US8829043B2 (enExample) |
| EP (1) | EP2254601B1 (enExample) |
| JP (1) | JP5704925B2 (enExample) |
| WO (1) | WO2009099670A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2254601B1 (en) | 2008-02-08 | 2019-05-29 | Nektar Therapeutics | Oligomer-cannabinoid conjugates |
| WO2011006099A1 (en) * | 2009-07-10 | 2011-01-13 | Northeastern University | Angiogenic resorcinol derivatives |
| US9827326B2 (en) | 2010-12-23 | 2017-11-28 | Nektar Therapeutics | Polymer-sunitinib conjugates |
| EP2654797B1 (en) | 2010-12-23 | 2017-11-08 | Nektar Therapeutics | Polymer-des-ethyl sunitinib conjugates |
| EP2903440B1 (de) | 2012-10-02 | 2017-09-06 | Bayer CropScience AG | Heterocyclische verbindungen als schädlingsbekämpfungsmittel |
| EP3538078A4 (en) * | 2016-11-11 | 2020-07-08 | Bennes, Inc. | FORMULATIONS FOR EFFICIENT CANNABINOID DELIVERY |
| WO2018176055A2 (en) | 2017-03-24 | 2018-09-27 | Trait Biosciences, Inc. | High level in vivo biosynthesis and isolation of water-soluble cannabinoids in plant systems |
| US11905543B2 (en) | 2017-07-11 | 2024-02-20 | Trait Biosceinces, Inc. | In vivo generation of water-soluble acetylated cannabinoid glycoside compounds in plant cell suspension cultures |
| US11946059B2 (en) | 2017-07-11 | 2024-04-02 | Trait Biosciences, Inc. | In vivo generation of water-soluble cannabinoids in plant cell suspension cultures |
| AU2018301674B2 (en) | 2017-07-11 | 2024-03-28 | Trait Biosciences, Inc. | Generation of water-soluble cannabinoid compounds in yeast and plant cell suspension cultures and compositions of matter |
| CA3179248C (en) * | 2019-05-23 | 2024-02-06 | Kare Chemical Technologies Inc. | Catalytic cannabinoid processes and precursors |
| JP2022539523A (ja) * | 2019-06-24 | 2022-09-12 | ダイヴァース バイオテック， インコーポレイテッド | カンナビノイド抱合分子 |
| WO2020263975A1 (en) | 2019-06-24 | 2020-12-30 | Diverse Biotech, Inc. | Beta-lactam-cannabinoid conjugate molecules |
| US12485181B2 (en) * | 2019-06-28 | 2025-12-02 | Serina Therapeutics (Al), Inc. | Polyoxazoline-drug conjugates with novel pharmacokinetic properties |
| CN110372627B (zh) * | 2019-07-04 | 2022-12-06 | 南昌大学 | 一种1,3,4-噁二唑衍生物及其制备方法和应用 |
| AU2020366257B2 (en) * | 2019-10-15 | 2025-01-23 | Diverse Biotech, Inc. | Conjugate molecules |
| CA3166630A1 (en) | 2020-01-03 | 2021-07-08 | Berg Llc | Polycyclic amides as ube2k modulators for treating cancer |
| WO2021211915A1 (en) * | 2020-04-17 | 2021-10-21 | University Of Connecticut | Polycannabinoids, compounds, compositions and methods of use |
| CN112592260A (zh) * | 2020-11-30 | 2021-04-02 | 云南苏理生物医药科技有限公司 | 一种大麻二酚的合成方法 |
| CA3240402A1 (en) * | 2021-12-09 | 2023-06-15 | Kamaluddin Abdur-Rashid | Catalytic tetrahydrocannabinol synthesis and precursors |
| CN115784836A (zh) * | 2022-12-08 | 2023-03-14 | 南京康立瑞生物科技有限公司 | 一种高选择性的制备反式-薄荷基-2,8-二烯-1-醇的方法 |
| US12480074B2 (en) | 2023-08-04 | 2025-11-25 | University Of Connecticut | Natural and synthetic cannabinoids as fluorescent tags; compositions, methods, and applications |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3968125A (en) | 1973-11-05 | 1976-07-06 | Eli Lilly And Company | Dihydroxyhexahydrodibenzo[b,d]pyrans |
| AU8763275A (en) * | 1975-01-13 | 1977-06-23 | Abbott Lab | Tri-cyclic compounds derived from phloroglucinol |
| GB1522057A (en) * | 1975-11-03 | 1978-08-23 | Pfizer | 9-hydroxydibenzo(b,d)pyrans and intermediates therefor |
| HU194858B (en) * | 1982-12-03 | 1988-03-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing dibenzo/b,d/pirane derivatives and pharmaceutical compositions containing them |
| FR2692575B1 (fr) | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| US5532237A (en) * | 1995-02-15 | 1996-07-02 | Merck Frosst Canada, Inc. | Indole derivatives with affinity for the cannabinoid receptor |
| US5672662A (en) | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
| FR2741621B1 (fr) * | 1995-11-23 | 1998-02-13 | Sanofi Sa | Nouveaux derives de pyrazole, procede pour leur preparation et compositions pharmaceutiques en contenant |
| WO2001003668A1 (en) | 1999-07-08 | 2001-01-18 | Her Majesty The Queen As Represented By The Minister Of National Defence Of Her Majesty's Canadian Government | Pulmonary delivery of liposome-encapsulated cannabinoids |
| US6835802B2 (en) | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
| BR0314172A (pt) | 2002-09-09 | 2005-07-26 | Nektar Therapeutics Al Corp | Polìmero solúvel em água, composição, forma de hidrato ou acetal, composto,composição, usos do composto e do conjugado, e, processo para preparar o conjugado |
| NZ540515A (en) | 2002-12-02 | 2008-01-31 | Astellas Pharma Inc | Pyrazole derivatives useful as COX-I inhibitors |
| FR2854896B1 (fr) * | 2003-05-16 | 2007-08-17 | Mayoly Spindler Lab | Nouveaux tensioactifs, compositions les comprenant |
| DK1694363T3 (en) | 2003-12-16 | 2014-03-24 | Nektar Therapeutics | Monodisperse PEGylated Naloxole Compositions |
| JP2006316054A (ja) * | 2005-04-15 | 2006-11-24 | Tanabe Seiyaku Co Ltd | 高コンダクタンス型カルシウム感受性ｋチャネル開口薬 |
| JP5069894B2 (ja) * | 2005-10-21 | 2012-11-07 | 田辺三菱製薬株式会社 | ピラゾール化合物 |
| WO2007046550A1 (en) * | 2005-10-21 | 2007-04-26 | Mitsubishi Tanabe Pharma Corporation | Pyrazole compounds having cannabinoid receptor (cb1) antagonizing activity |
| JP2010535238A (ja) | 2007-07-30 | 2010-11-18 | オールトランツ インコーポレイティド | カンナビジオールのプロドラッグ、カンナビジオールのプロドラッグを含む組成物及びその使用方法 |
| PL2963031T3 (pl) * | 2007-11-30 | 2019-08-30 | Zynerba Pharmaceuticals, Inc. | Proleki tetrahydrokannabinolu, kompozycje zawierające proleki tetrahydrokannabinolu i sposoby ich stosowania |
| EP2254601B1 (en) | 2008-02-08 | 2019-05-29 | Nektar Therapeutics | Oligomer-cannabinoid conjugates |
-
2009
- 2009-02-06 EP EP09708118.6A patent/EP2254601B1/en active Active
- 2009-02-06 US US12/865,372 patent/US8829043B2/en active Active
- 2009-02-06 JP JP2010545891A patent/JP5704925B2/ja not_active Expired - Fee Related
- 2009-02-06 WO PCT/US2009/000810 patent/WO2009099670A2/en not_active Ceased
-
2014
- 2014-07-22 US US14/338,111 patent/US9155797B2/en not_active Expired - Fee Related
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