JP2011511075A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011511075A5 JP2011511075A5 JP2010545891A JP2010545891A JP2011511075A5 JP 2011511075 A5 JP2011511075 A5 JP 2011511075A5 JP 2010545891 A JP2010545891 A JP 2010545891A JP 2010545891 A JP2010545891 A JP 2010545891A JP 2011511075 A5 JP2011511075 A5 JP 2011511075A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- unsubstituted
- alkoxy
- phenyl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 Cc1c(CCN2CCOCC2)c2cc(**)ccc2[n]1C(c(cccc1Cl)c1Cl)=O Chemical compound Cc1c(CCN2CCOCC2)c2cc(**)ccc2[n]1C(c(cccc1Cl)c1Cl)=O 0.000 description 5
- JZCPYUJPEARBJL-UHFFFAOYSA-N Cc1c(-c(cc2)ccc2Cl)[n](-c(c(Cl)c2)ccc2Cl)nc1C(NN1CCCCC1)=O Chemical compound Cc1c(-c(cc2)ccc2Cl)[n](-c(c(Cl)c2)ccc2Cl)nc1C(NN1CCCCC1)=O JZCPYUJPEARBJL-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6508908P | 2008-02-08 | 2008-02-08 | |
| US61/065,089 | 2008-02-08 | ||
| PCT/US2009/000810 WO2009099670A2 (en) | 2008-02-08 | 2009-02-06 | Oligomer-cannabinoid conjugates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011511075A JP2011511075A (ja) | 2011-04-07 |
| JP2011511075A5 true JP2011511075A5 (enExample) | 2013-01-31 |
| JP5704925B2 JP5704925B2 (ja) | 2015-04-22 |
Family
ID=40602328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010545891A Expired - Fee Related JP5704925B2 (ja) | 2008-02-08 | 2009-02-06 | オリゴマー−カンナビノイドコンジュゲート |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US8829043B2 (enExample) |
| EP (1) | EP2254601B1 (enExample) |
| JP (1) | JP5704925B2 (enExample) |
| WO (1) | WO2009099670A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8829043B2 (en) | 2008-02-08 | 2014-09-09 | Nektar Therapeutics | Oligome-cannabinoid conjugates |
| US20120172339A1 (en) * | 2009-07-10 | 2012-07-05 | Northeastern University | Angiogenic resorcinol derivatives |
| US10220020B2 (en) | 2010-12-23 | 2019-03-05 | Nektar Therapeutics | Polymer-des-ethyl sunitinib conjugates |
| WO2012088529A1 (en) | 2010-12-23 | 2012-06-28 | Nektar Therapeutics | Polymer-sunitinib conjugates |
| ES2651074T3 (es) | 2012-10-02 | 2018-01-24 | Bayer Cropscience Ag | Compuestos heterocíclicos como plaguicidas |
| CA3046638A1 (en) * | 2016-11-11 | 2018-05-17 | Bennes, Inc. | Formulations for efficient delivery of cannabinoids |
| AU2018239671B2 (en) | 2017-03-24 | 2024-08-15 | Trait Biosciences, Inc. | High level In vivo biosynthesis and isolation of water-soluble cannabinoids in plant systems |
| EP3730145A1 (en) | 2017-07-11 | 2020-10-28 | Trait Biosciences, Inc. | Generation of water-soluble cannabinoid compounds in yeast and plant cell suspension cultures and compositions of matter |
| US11905543B2 (en) | 2017-07-11 | 2024-02-20 | Trait Biosceinces, Inc. | In vivo generation of water-soluble acetylated cannabinoid glycoside compounds in plant cell suspension cultures |
| US11946059B2 (en) | 2017-07-11 | 2024-04-02 | Trait Biosciences, Inc. | In vivo generation of water-soluble cannabinoids in plant cell suspension cultures |
| KR20220012298A (ko) * | 2019-05-23 | 2022-02-03 | 카레 케미컬 테크놀로지스 인코포레이티드 | 촉매 칸나비노이드 공정 및 전구체 |
| EP3986388A4 (en) * | 2019-06-24 | 2024-02-21 | Diverse Biotech, Inc. | CANNABINOID CONJUGATE MOLECULES |
| US12257307B2 (en) | 2019-06-24 | 2025-03-25 | Diverse Biotech, Inc. | β-lactam-cannabinoid conjugate molecules |
| US12485181B2 (en) * | 2019-06-28 | 2025-12-02 | Serina Therapeutics (Al), Inc. | Polyoxazoline-drug conjugates with novel pharmacokinetic properties |
| CN110372627B (zh) * | 2019-07-04 | 2022-12-06 | 南昌大学 | 一种1,3,4-噁二唑衍生物及其制备方法和应用 |
| EP4045023A4 (en) | 2019-10-15 | 2023-09-13 | Diverse Biotech, Inc. | CONJUGATED MOLECULES |
| AU2020417293A1 (en) | 2020-01-03 | 2022-09-01 | Berg Llc | Polycyclic amides as UBE2K modulators for treating cancer |
| US12491199B2 (en) | 2020-04-17 | 2025-12-09 | University Of Connecticut | Polycannabinoids, compounds, compositions and methods of use |
| CN112592260A (zh) * | 2020-11-30 | 2021-04-02 | 云南苏理生物医药科技有限公司 | 一种大麻二酚的合成方法 |
| WO2023102655A1 (en) * | 2021-12-09 | 2023-06-15 | Kare Chemical Technologies Inc. | Catalytic tetrahydrocannabinol synthesis and precursors |
| CN115784836A (zh) * | 2022-12-08 | 2023-03-14 | 南京康立瑞生物科技有限公司 | 一种高选择性的制备反式-薄荷基-2,8-二烯-1-醇的方法 |
| WO2025034533A1 (en) | 2023-08-04 | 2025-02-13 | University Of Connecticut | Natural and synthetic cannabinoids as fluorescent tags; compositions, methods, and applications |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3968125A (en) * | 1973-11-05 | 1976-07-06 | Eli Lilly And Company | Dihydroxyhexahydrodibenzo[b,d]pyrans |
| AU8763275A (en) * | 1975-01-13 | 1977-06-23 | Abbott Lab | Tri-cyclic compounds derived from phloroglucinol |
| GB1522057A (en) * | 1975-11-03 | 1978-08-23 | Pfizer | 9-hydroxydibenzo(b,d)pyrans and intermediates therefor |
| HU194858B (en) | 1982-12-03 | 1988-03-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing dibenzo/b,d/pirane derivatives and pharmaceutical compositions containing them |
| FR2692575B1 (fr) | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| US5532237A (en) | 1995-02-15 | 1996-07-02 | Merck Frosst Canada, Inc. | Indole derivatives with affinity for the cannabinoid receptor |
| US5672662A (en) | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
| FR2741621B1 (fr) * | 1995-11-23 | 1998-02-13 | Sanofi Sa | Nouveaux derives de pyrazole, procede pour leur preparation et compositions pharmaceutiques en contenant |
| CA2341035A1 (en) | 1999-07-08 | 2001-01-18 | Orlando Hung | Pulmonary delivery of liposomal-encapsulated cannabinoids |
| US6835802B2 (en) | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
| KR100974843B1 (ko) * | 2002-09-09 | 2010-08-11 | 넥타르 테라퓨틱스 | 수용성 중합체 알카날 |
| JP4419078B2 (ja) | 2002-12-02 | 2010-02-24 | アステラス製薬株式会社 | ピラゾール誘導体 |
| FR2854896B1 (fr) * | 2003-05-16 | 2007-08-17 | Mayoly Spindler Lab | Nouveaux tensioactifs, compositions les comprenant |
| HRP20140361T1 (hr) | 2003-12-16 | 2014-05-23 | Nektar Therapeutics | Monodisperzne smjese pegiliranog naloksola |
| JP2006316054A (ja) * | 2005-04-15 | 2006-11-24 | Tanabe Seiyaku Co Ltd | 高コンダクタンス型カルシウム感受性ｋチャネル開口薬 |
| JP5069894B2 (ja) * | 2005-10-21 | 2012-11-07 | 田辺三菱製薬株式会社 | ピラゾール化合物 |
| WO2007046550A1 (en) * | 2005-10-21 | 2007-04-26 | Mitsubishi Tanabe Pharma Corporation | Pyrazole compounds having cannabinoid receptor (cb1) antagonizing activity |
| ES2534900T3 (es) * | 2007-07-30 | 2015-04-30 | Zynerba Pharmaceuticals, Inc. | Profármacos de cannabidiol, composiciones que comprenden los profármacos de cannabidiol y métodos de uso de los mismos |
| JP5551604B2 (ja) * | 2007-11-30 | 2014-07-16 | オールトランツ インコーポレイティド | テトラヒドロカンナビノールのプロドラッグ、テトラヒドロカンナビノールのプロドラッグを含む組成物、及び同一のものを使用する方法 |
| US8829043B2 (en) | 2008-02-08 | 2014-09-09 | Nektar Therapeutics | Oligome-cannabinoid conjugates |
-
2009
- 2009-02-06 US US12/865,372 patent/US8829043B2/en active Active
- 2009-02-06 JP JP2010545891A patent/JP5704925B2/ja not_active Expired - Fee Related
- 2009-02-06 WO PCT/US2009/000810 patent/WO2009099670A2/en not_active Ceased
- 2009-02-06 EP EP09708118.6A patent/EP2254601B1/en active Active
-
2014
- 2014-07-22 US US14/338,111 patent/US9155797B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011500545A5 (enExample) | ||
| CZ228295A3 (en) | The use of carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation | |
| RU2490250C2 (ru) | Спиросоединения и их фармацевтическое применение | |
| JP2016518437A5 (enExample) | ||
| WO2007082808A3 (en) | Thiazoles as 11 beta-hsd1 inhibitors | |
| JP2009536933A5 (enExample) | ||
| JP2008195730A5 (enExample) | ||
| WO2007060140A3 (en) | Inhibitors of diacyglycerol acyltransferase (dgat) | |
| WO2012018534A3 (en) | Substituted biphenylene compounds and methods of use thereof for the treatment of viral diseases | |
| WO2009010416A3 (en) | Inhibitors of 11b-hydroxysteroid dehydrogenase | |
| JP2009536620A5 (enExample) | ||
| JP2009502743A5 (enExample) | ||
| JP2006501201A5 (enExample) | ||
| JP2010529147A5 (enExample) | ||
| JP2009523777A5 (enExample) | ||
| JP2002513793A5 (enExample) | ||
| MX2008002061A (es) | Derivados de tiazolil piperidina utiles como moduladores del receptor h3. | |
| JP2011526247A5 (enExample) | ||
| JP2005536503A5 (enExample) | ||
| ATE279192T1 (de) | Die verwendung eines benzimidazoles zur herstellung eines medikamentes zur krebsvorbeugung | |
| JP2009520695A5 (enExample) | ||
| JP2013506674A5 (enExample) | ||
| WO2008039406A3 (en) | Rapidly disintegrating lyophilized oral formulations of a thrombin receptor antagonist | |
| WO2010012745A3 (en) | Benzimidazoles | |
| JP2004521150A5 (enExample) |