JP2011508726A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011508726A5 JP2011508726A5 JP2010538198A JP2010538198A JP2011508726A5 JP 2011508726 A5 JP2011508726 A5 JP 2011508726A5 JP 2010538198 A JP2010538198 A JP 2010538198A JP 2010538198 A JP2010538198 A JP 2010538198A JP 2011508726 A5 JP2011508726 A5 JP 2011508726A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- ligand
- alkyl
- aryl
- occurrence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003446 ligand Substances 0.000 claims 22
- 125000000217 alkyl group Chemical group 0.000 claims 14
- 125000003118 aryl group Chemical group 0.000 claims 11
- 125000000753 cycloalkyl group Chemical group 0.000 claims 10
- 125000003710 aryl alkyl group Chemical group 0.000 claims 9
- 125000001072 heteroaryl group Chemical group 0.000 claims 9
- 125000004475 heteroaralkyl group Chemical group 0.000 claims 8
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 6
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 2
- 150000004703 alkoxides Chemical class 0.000 claims 2
- 125000004103 aminoalkyl group Chemical group 0.000 claims 2
- 125000004429 atom Chemical group 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 125000005842 heteroatom Chemical group 0.000 claims 2
- 125000004415 heterocyclylalkyl group Chemical group 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 229910052763 palladium Inorganic materials 0.000 claims 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 2
- 239000010452 phosphate Substances 0.000 claims 2
- 229910052697 platinum Inorganic materials 0.000 claims 2
- 125000003107 substituted aryl group Chemical group 0.000 claims 2
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 2
- 229910052723 transition metal Inorganic materials 0.000 claims 2
- 150000003624 transition metals Chemical class 0.000 claims 2
- -1 1- adamantyl Chemical group 0.000 claims 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 125000000392 cycloalkenyl group Chemical group 0.000 claims 1
- 125000004404 heteroalkyl group Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 150000004678 hydrides Chemical class 0.000 claims 1
- 229910052740 iodine Inorganic materials 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229910052759 nickel Inorganic materials 0.000 claims 1
- 125000005010 perfluoroalkyl group Chemical group 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 125000004665 trialkylsilyl group Chemical group 0.000 claims 1
- 125000005106 triarylsilyl group Chemical group 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1317407P | 2007-12-12 | 2007-12-12 | |
| US61/013,174 | 2007-12-12 | ||
| US8736808P | 2008-08-08 | 2008-08-08 | |
| US61/087,368 | 2008-08-08 | ||
| PCT/US2008/086651 WO2009076622A2 (en) | 2007-12-12 | 2008-12-12 | Ligands for transition-metal-catalyzed cross-couplings, and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011508726A JP2011508726A (ja) | 2011-03-17 |
| JP2011508726A5 true JP2011508726A5 (enExample) | 2012-02-02 |
| JP5591714B2 JP5591714B2 (ja) | 2014-09-17 |
Family
ID=40756138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538198A Active JP5591714B2 (ja) | 2007-12-12 | 2008-12-12 | 遷移金属触媒によるクロスカップリングのためのリガンド、およびその使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7858784B2 (enExample) |
| EP (1) | EP2231680B1 (enExample) |
| JP (1) | JP5591714B2 (enExample) |
| CN (1) | CN101952298B (enExample) |
| CA (1) | CA2708369C (enExample) |
| WO (1) | WO2009076622A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5803042B2 (ja) * | 2010-04-05 | 2015-11-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | クロスカップリング反応におけるモノリン配位子及びそれらの使用 |
| EA030228B1 (ru) | 2010-07-16 | 2018-07-31 | ЭббВи Айэленд Анлимитед Компани | Фосфиновые лиганды для каталитических реакций |
| US9255074B2 (en) | 2010-07-16 | 2016-02-09 | Abbvie Inc. | Process for preparing antiviral compounds |
| US8975443B2 (en) | 2010-07-16 | 2015-03-10 | Abbvie Inc. | Phosphine ligands for catalytic reactions |
| PH12013500105A1 (en) | 2010-07-16 | 2013-02-25 | Abbvie Bahamas Ltd | Process for preparing antiviral compounds |
| CN102241614B (zh) * | 2011-05-10 | 2015-09-02 | 浙江建业化工股份有限公司 | 一种n-烃基取代酰胺化合物的合成方法 |
| CN102516300A (zh) * | 2011-11-09 | 2012-06-27 | 中山大学 | 一类膦配体及其对映体或消旋体及其制备方法 |
| CN102557966A (zh) * | 2011-12-23 | 2012-07-11 | 中国石油化工股份有限公司 | 一种制备防老剂dtpd的方法 |
| WO2013159229A1 (en) * | 2012-04-24 | 2013-10-31 | Dalhousie University | Silanyloxyaryl phosphine ligand and uses thereof in c-n cross-coupling |
| US8889857B2 (en) * | 2012-06-08 | 2014-11-18 | Massachusetts Institute Of Technology | Phosphine-ligated palladium sulfonate palladacycles |
| WO2014007405A1 (ja) * | 2012-07-06 | 2014-01-09 | 住友化学株式会社 | 芳香族化合物の製造方法 |
| CN104540871B (zh) * | 2012-07-06 | 2016-08-24 | 住友化学株式会社 | 芳香族化合物的制备方法 |
| JP6666147B2 (ja) | 2012-09-26 | 2020-03-13 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 環状エーテルピラゾール−４−イル−ヘテロシクリル−カルボキサミド化合物と使用方法 |
| EP2906566B1 (en) | 2012-10-10 | 2016-08-24 | F. Hoffmann-La Roche AG | Process for making thienopyrimidine compounds |
| WO2014078669A1 (en) * | 2012-11-15 | 2014-05-22 | Duquesne University Of The Holy Ghost | Carboxylic acid ester prodrug inhibitors of mek |
| US10093692B2 (en) | 2013-09-18 | 2018-10-09 | The Hong Kong Polytechnic University | Phosphines, synthesis thereof and their use in catalysis |
| CA2929918C (en) | 2013-12-05 | 2018-01-23 | F. Hoffmann-La Roche Ag | Heteroaryl pyridone and aza-pyridone compounds with electrophilic functionality |
| CN103819369B (zh) * | 2014-03-11 | 2016-06-01 | 杨雪飞 | 一种苯磺酰胺类化合物的合成方法 |
| MX2016012007A (es) | 2014-03-18 | 2016-12-05 | Hoffmann La Roche | Compuestos de oxepan-2-il-pirazol-4-il-heterociclil-carboxamida y metodos de uso. |
| US9394387B2 (en) | 2014-05-15 | 2016-07-19 | Chevron Phillips Chemical Company Lp | Synthesis of aryl coupled bis phenoxides and their use in olefin polymerization catalyst systems with activator-supports |
| WO2016094489A1 (en) | 2014-12-10 | 2016-06-16 | The Regents Of The University Of California | Phosphorus ligands and methods of use |
| CN106588983B (zh) * | 2015-10-14 | 2021-10-01 | 香港理工大学深圳研究院 | 咔唑基磷配体、及其制备方法和应用 |
| CN105273006B (zh) * | 2015-11-02 | 2017-09-19 | 盘锦格林凯默科技有限公司 | 2‑二环己基膦‑2,4,6‑三异丙基联苯的制备方法 |
| US20170173569A1 (en) | 2015-12-16 | 2017-06-22 | Bruce H. Lipshutz | Fe-ppm Pd, Cu and/or Ni Nanoparticle-Catalyzed Reactions in Water |
| US20180117574A1 (en) | 2016-10-31 | 2018-05-03 | The Regents Of The University Of California | Biaryl ligands for transition metal-catalyzed reactions |
| CN109956970A (zh) * | 2017-12-26 | 2019-07-02 | 南开大学 | 联苯型三齿配体钌络合物及其制备方法和应用 |
| CN110240616B (zh) | 2018-03-07 | 2021-03-23 | 东莞市均成高新材料有限公司 | 三联芳单膦配体、它们的制备方法和在催化偶联反应中的用途 |
| JP7041092B2 (ja) * | 2019-04-05 | 2022-03-23 | 日本化学工業株式会社 | ビアリールホスフィンの製造方法 |
| CN113019463B (zh) * | 2021-05-25 | 2021-09-07 | 江苏欣诺科催化剂有限公司 | 钯复合催化剂及其制备方法和应用 |
| WO2024171068A1 (en) * | 2023-02-15 | 2024-08-22 | Indian Institute Of Technology Bombay | Development of ligands for metals and metal-catalyzed reactions |
| CN120916761A (zh) * | 2023-03-10 | 2025-11-07 | 弗莱克斯塞思知识产权控股有限责任公司 | 喹啉亚胺抗降解剂化合物及其用途 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51132190A (en) | 1975-03-04 | 1976-11-17 | Agency Of Ind Science & Technol | Complex catalist for asymmetric reaction |
| SE449456B (sv) * | 1983-11-15 | 1987-05-04 | Uponor Ab | Forfarande och anordning for framstellning av ror varvid formbacksdelarna er delade i formstreckans lengsriktning |
| US4885376A (en) | 1987-10-13 | 1989-12-05 | Iowa State University Research Foundation, Inc. | New types of organometallic reagents and catalysts for asymmetric synthesis |
| JP2733880B2 (ja) | 1991-03-12 | 1998-03-30 | 高砂香料工業株式会社 | 光学活性三級ホスフィン化合物およびこれを配位子とする遷移金属錯体 |
| JP2939510B2 (ja) | 1991-10-04 | 1999-08-25 | 一雄 阿知波 | 新規な非対称軸不斉アミノホスフィン誘導体 |
| US5739396A (en) | 1991-12-09 | 1998-04-14 | Stanford University | Asymmetric ligands useful for transition metal catalyzed bond forming reactions |
| US5508438A (en) * | 1992-01-31 | 1996-04-16 | Hoffmann-La Roche Inc. | Phosphorus compounds |
| US5530150A (en) | 1993-03-12 | 1996-06-25 | Takasago International Corporation | Phosphine compound, complex containing the phosphine compound as ligand, process for producing optically active aldehyde using the phosphine compound or the complex, and 4-[(R)-1'-formylethyl]azetidin-2-one derivatives |
| DE4338826A1 (de) | 1993-11-13 | 1995-05-18 | Hoechst Ag | Verfahren zur Herstellung von 1,1`-Binaphthylen |
| JPH07330786A (ja) | 1994-06-09 | 1995-12-19 | Sumitomo Chem Co Ltd | 光学活性３級ホスフィン化合物、これを配位子とする遷移金属錯体およびこれを用いる製造法 |
| DE4435189A1 (de) | 1994-09-30 | 1996-04-04 | Hoechst Ag | Neue sulfonierte Phosphine, Verfahren zu ihrer Herstellung und ihre Verwendung als Bestandteil von Katalysatorsystemen |
| US5621129A (en) | 1995-03-09 | 1997-04-15 | Sumitomo Chemical Co., Ltd. | Optically active tertiary phosphine compound, transition metal complex comprising the same as ligand and process for preparing optically active organic silicon compound using said transition metal complex |
| US5508458A (en) | 1995-05-26 | 1996-04-16 | Hoechst Celanese Corporation | Chiral catalysts and processes for preparing the same |
| US5567856A (en) | 1995-05-30 | 1996-10-22 | Hoechst Celanese Corporation | Synthesis of and hydroformylation with fluoro-substituted bidentate phosphine ligands |
| JPH11514356A (ja) | 1995-10-13 | 1999-12-07 | ザ ペン ステイト リサーチ ファウンデイション | 新しいキラルリガンドを有する遷移金属錯体により触媒される不斉合成 |
| JP3430775B2 (ja) | 1996-03-01 | 2003-07-28 | 住友化学工業株式会社 | ３級ホスフィン化合物、これを配位子とする遷移金属錯体およびその用途 |
| JP3431749B2 (ja) | 1996-03-07 | 2003-07-28 | 高砂香料工業株式会社 | 新規な１−置換−２−ジフェニルホスフィノナフタレンおよびこれを配位子とする遷移金属錯体 |
| US5929281A (en) | 1996-04-19 | 1999-07-27 | Tosoh Corporation | Process for producing heterocyclic aromatic amine or arylamine |
| US5817877A (en) | 1996-09-23 | 1998-10-06 | Yale University | Metal-catalyzed amination of organic sulfonates to organic amines |
| US5847166A (en) | 1996-10-10 | 1998-12-08 | Massachusetts Institute Of Technology | Synthesis of aryl ethers |
| EP0849274A1 (en) | 1996-12-20 | 1998-06-24 | Schering Aktiengesellschaft | Bissteroidal compounds and their use for the preparation of chiral complexes |
| US6395916B1 (en) * | 1998-07-10 | 2002-05-28 | Massachusetts Institute Of Technology | Ligands for metals and improved metal-catalyzed processes based thereon |
| US6307087B1 (en) | 1998-07-10 | 2001-10-23 | Massachusetts Institute Of Technology | Ligands for metals and improved metal-catalyzed processes based thereon |
| US7223879B2 (en) | 1998-07-10 | 2007-05-29 | Massachusetts Institute Of Technology | Ligands for metals and improved metal-catalyzed processes based thereon |
| US6100398A (en) | 1998-10-14 | 2000-08-08 | Yale University | Transition metal-catalyzed process for preparing N-aryl amine compounds |
| US6380392B1 (en) * | 1999-06-30 | 2002-04-30 | The Penn State Research Foundation | Ligands based on chiral 2-amino-2′-hydroxy-1,1′-binaphthyl and related frameworks for asymmetric catalysis |
| HK1046267A1 (zh) * | 1999-08-23 | 2003-01-03 | The Penn State Research Foundation | 手性磷化氢配体、其过渡金属复合物，及二者在不对称反应中的应用 |
| WO2003006420A1 (en) | 2001-07-12 | 2003-01-23 | Yale University | Catalytic method to convert aryl compounds to aryl amines |
| EP2583958B1 (en) * | 2002-12-09 | 2016-08-10 | Massachusetts Institute of Technology (MIT) | Ligands for metals and improved metal-catalyzed processes based thereon |
| WO2006074315A2 (en) | 2005-01-10 | 2006-07-13 | Massachusetts Institute Of Technology | Transition-metal-catalyzed carbon-nitrogen and carbon-carbon bond-forming reactions |
| US7833927B2 (en) * | 2005-08-31 | 2010-11-16 | Rohm And Haas Company | Single site palladium catalyst complexes |
| DE102005046344A1 (de) * | 2005-09-28 | 2007-03-29 | Saltigo Gmbh | Verfahren zur Kupplung von Benzylaminen mit Halogenaromaten |
-
2008
- 2008-12-12 US US12/334,083 patent/US7858784B2/en active Active
- 2008-12-12 CN CN200880126921.5A patent/CN101952298B/zh active Active
- 2008-12-12 WO PCT/US2008/086651 patent/WO2009076622A2/en not_active Ceased
- 2008-12-12 CA CA2708369A patent/CA2708369C/en active Active
- 2008-12-12 JP JP2010538198A patent/JP5591714B2/ja active Active
- 2008-12-12 EP EP08860439.2A patent/EP2231680B1/en active Active