JP2011501958A - ブタDC−SIGN、ICAM−3およびLSECtinならびにそれらの使用 - Google Patents

ブタDC−SIGN、ICAM−3およびLSECtinならびにそれらの使用 Download PDF

Info

Publication number
JP2011501958A
JP2011501958A JP2010532042A JP2010532042A JP2011501958A JP 2011501958 A JP2011501958 A JP 2011501958A JP 2010532042 A JP2010532042 A JP 2010532042A JP 2010532042 A JP2010532042 A JP 2010532042A JP 2011501958 A JP2011501958 A JP 2011501958A
Authority
JP
Japan
Prior art keywords
virus
sign
cells
porcine
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010532042A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011501958A5 (https=
Inventor
フアン・ヤオウェイ
シャン−ジン・メン
Original Assignee
バージニア テック インテレクチュアル プロパティーズ インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バージニア テック インテレクチュアル プロパティーズ インコーポレーテッド filed Critical バージニア テック インテレクチュアル プロパティーズ インコーポレーテッド
Publication of JP2011501958A publication Critical patent/JP2011501958A/ja
Publication of JP2011501958A5 publication Critical patent/JP2011501958A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70525ICAM molecules, e.g. CD50, CD54, CD102
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056Lectin superfamily, e.g. CD23, CD72

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2010532042A 2007-10-29 2008-10-29 ブタDC−SIGN、ICAM−3およびLSECtinならびにそれらの使用 Pending JP2011501958A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80007P 2007-10-29 2007-10-29
PCT/US2008/012251 WO2009058285A2 (en) 2007-10-29 2008-10-29 PORCINE DC-SIGN, ICAM-3 AND LSECtin AND USES THEREOF

Publications (2)

Publication Number Publication Date
JP2011501958A true JP2011501958A (ja) 2011-01-20
JP2011501958A5 JP2011501958A5 (https=) 2011-12-15

Family

ID=40591693

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010532042A Pending JP2011501958A (ja) 2007-10-29 2008-10-29 ブタDC−SIGN、ICAM−3およびLSECtinならびにそれらの使用

Country Status (14)

Country Link
US (1) US8415118B2 (https=)
EP (2) EP2662384A1 (https=)
JP (1) JP2011501958A (https=)
KR (1) KR20100087344A (https=)
CN (1) CN102066415A (https=)
AU (1) AU2008319384A1 (https=)
BR (1) BRPI0818477A2 (https=)
CA (1) CA2704207A1 (https=)
CO (1) CO6270367A2 (https=)
MX (1) MX2010004548A (https=)
NZ (1) NZ584893A (https=)
RU (1) RU2010121862A (https=)
WO (1) WO2009058285A2 (https=)
ZA (1) ZA201002773B (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201503351RA (en) 2010-01-19 2015-06-29 Harvard College Engineered Opsonin for Pathogen Detection and Treatment
AU2012284097B2 (en) 2011-07-18 2017-08-03 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
EP2798069B1 (en) 2011-12-15 2017-03-29 Washington University Porcine knob xenotype chimeric adenoviral vector for dendritic cell infection
WO2013130875A1 (en) 2012-02-29 2013-09-06 President And Fellows Of Harvard College Rapid antibiotic susceptibility testing
CA2862516C (en) 2012-03-27 2023-02-14 Ngm Biopharmaceuticals, Inc. Compositions and methods of use for treating metabolic disorders
WO2014144325A1 (en) 2013-03-15 2014-09-18 President And Fellows Of Harvard College Methods and compositions for improving detection and/or capture of a target entity
JP6649250B2 (ja) 2013-05-21 2020-02-19 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 操作されたヘム結合性構成物およびその使用
US10513546B2 (en) 2013-12-18 2019-12-24 President And Fellows Of Harvard College CRP capture/detection of gram positive bacteria
AU2015296640B2 (en) * 2014-07-30 2020-05-21 Ngm Biopharmaceuticals, Inc. Compositions and methods of use for treating metabolic disorders
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
EP3701969A1 (en) 2014-10-31 2020-09-02 NGM Biopharmaceuticals, Inc. Compositions and methods of use for treating metabolic disorders
CN104749361B (zh) * 2015-01-21 2017-04-19 中国农业科学院哈尔滨兽医研究所 猪圆环病毒2型抗原捕获elisa试剂盒
CN105445457B (zh) * 2015-03-24 2017-08-11 中国农业科学院哈尔滨兽医研究所 检测猪圆环病毒2型Cap蛋白的单克隆抗体及试剂盒
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
EP3331549B1 (en) 2015-08-06 2020-12-23 President and Fellows of Harvard College Improved microbe-binding molecules and uses thereof
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN106957847A (zh) * 2017-05-16 2017-07-18 吉林大学 有效抑制仔猪流行性腹泻病毒的siRNA及用途
CN107488635A (zh) * 2017-09-22 2017-12-19 中国人民解放军第三军医大学第三附属医院 单克隆细胞及其制备方法和用途
CN108893474B (zh) * 2018-02-07 2021-11-16 电子科技大学 草鱼细胞间粘附分子基因的分离和鉴定
CN108977444A (zh) * 2018-06-28 2018-12-11 西南大学 沉默荣昌猪CD14表达的siRNA及筛选方法与应用
CN109679952B (zh) * 2018-12-24 2022-04-15 西北农林科技大学 一种抗PRRSV感染的猪源miR-c89及其应用
CN109652384B (zh) * 2019-02-21 2021-10-26 昆明理工大学 一种体外培养戊型肝炎病毒的方法
CN109836478B (zh) * 2019-03-19 2022-06-14 扬州大学 非洲猪瘟病毒p11.5蛋白特异性多克隆抗体的制备方法及应用
CN109943536B (zh) * 2019-03-26 2021-09-14 昆明理工大学 一种戊型肝炎病毒的培养方法及其灭活疫苗的制备方法
CN111575409B (zh) * 2020-05-23 2023-04-18 黑龙江八一农垦大学 基于整合素配体识别肽抑制猪流行性腹泻病毒感染的研究方法
WO2022050476A1 (ko) * 2020-09-04 2022-03-10 이형우 인간 면역결핍 바이러스 감염 또는 감염 질환의 치료용 조성물
CN115725656B (zh) * 2021-09-01 2026-01-16 联邦生物科技(珠海横琴)有限公司 一种以细胞质rna病毒为载体递送干扰rna的方法
CN121454060A (zh) * 2026-01-05 2026-02-03 江苏立维斯德生物技术有限公司 一种基于免疫荧光法检测轮状病毒的方法、试剂盒及其用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07509599A (ja) * 1992-06-11 1995-10-26 ニューヨーク ユニバーシティー キメラ受容体ポリペプチド,ヒトh13タンパク質,ならびにその使用
JP2002543762A (ja) * 1999-03-25 2002-12-24 ブリストル−マイヤーズ スクイブ カンパニー ヒトclaxタンパク質およびその可溶性融合タンパク質をコードするdna分子

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9409768D0 (en) 1994-05-16 1994-07-06 Medical Res Council Trimerising polypeptides
US6146873A (en) 1994-11-10 2000-11-14 Baxter Aktiengesellschaft Production of orthomyxoviruses in monkey kidney cells using protein-free media
US6280953B1 (en) 1998-01-30 2001-08-28 Evolutionary Genomics, L.L.C. Methods to identify polynucleotide and polypeptide sequences which may be associated with physiological and medical conditions
CN1355690A (zh) 1999-04-16 2002-06-26 奥赛尔股份有限公司 一种延长可溶性病毒特异性配体在粘膜上半寿期的方法
EP1046651A1 (en) 1999-04-19 2000-10-25 Koninklijke Universiteit Nijmegen Composition and method for modulating dendritic cell-T interaction
US6391567B1 (en) 2000-03-02 2002-05-21 New York University Identifying compounds inhibiting DC-sign facilitation of HIV into cells
GB0318247D0 (en) * 2003-08-05 2003-09-10 Royal Veterinary College Antigen delivery system
CA2563432A1 (en) 2004-04-16 2005-12-01 Genentech, Inc. Method for augmenting b cell depletion

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07509599A (ja) * 1992-06-11 1995-10-26 ニューヨーク ユニバーシティー キメラ受容体ポリペプチド,ヒトh13タンパク質,ならびにその使用
JP2002543762A (ja) * 1999-03-25 2002-12-24 ブリストル−マイヤーズ スクイブ カンパニー ヒトclaxタンパク質およびその可溶性融合タンパク質をコードするdna分子

Non-Patent Citations (15)

* Cited by examiner, † Cited by third party
Title
JPN6013031838; HUANG, Y.W. et al.: Dev. Comp. Immunol. , 20081023, pp.464-480 *
JPN6013031839; TEUNIS, B. et al.: J. Biol. Chem. Vol.277, 2002, pp.11314-11320 *
JPN6013031840; LEEB, T. and MULLER, M.: Gene Vol.343, 2004, pp.239-244 *
JPN6013031841; PARK, C.G. et al.: Int. Immunol. Vol.13, No.10, 2001, pp.1283-1290 *
JPN6013031843; POWLESLAND, A.S. et al.: J. Biol. Chem. Vol.283, 20071105, pp.593-602 *
JPN6013031845; LOVING, C.L. et al.: Immunology Vol.120, 2006, pp.217-229 *
JPN6013031847; BOWDEN, T.A. et al.: J. Virol. Vol.82,No.23, 20080924, pp.11628-11636 *
JPN6013031849; UENISHI, H.: '"CJ007777 full-length enriched swine cDNA library, adult mesenteric lymph node Sus scrofa cDNA clone' GenBank Accession no. CJ007777 *
JPN6013031851; LEEB, T.: '"Sus scrofa partial ICAM3 gene, TYK2, CDC37, PDE4A, KEAP1, EDG8 and APG4D genes and partial FLJ12949' GenBank Accession no. AJ632303 , 20061115 *
JPN6013031853; BASHIROVA, A.A. et al.: J. Virol. Vol.77, No.1, 2003, pp.217-227 *
JPN6013031855; BARIBAUD, F. et al.: J. Virol. Vol.75, No.21, 2001, pp.10281-10289 *
JPN6013031857; LIU, W. et al.: J. Biol. Chem. Vol.279, No.18, 2004, pp.18748-18758 *
JPN6013031859; PAILLOT, R. et al.: Immunology Vol.102, 2001, pp.396-404 *
JPN6013031860; REEVES, J.D. et al.: J. Gen. Virol. Vol.79, 1998, pp.1793-1799 *
JPN6013031862; KARLSSON, I. et al.: AIDS Vol.17, 2003, pp.2561-2569 *

Also Published As

Publication number Publication date
KR20100087344A (ko) 2010-08-04
BRPI0818477A2 (pt) 2015-04-14
US20100317054A1 (en) 2010-12-16
US8415118B2 (en) 2013-04-09
EP2207798A2 (en) 2010-07-21
WO2009058285A9 (en) 2009-07-09
CN102066415A (zh) 2011-05-18
NZ584893A (en) 2012-08-31
AU2008319384A1 (en) 2009-05-07
WO2009058285A2 (en) 2009-05-07
EP2662384A1 (en) 2013-11-13
WO2009058285A3 (en) 2009-12-10
CO6270367A2 (es) 2011-04-20
ZA201002773B (en) 2011-10-26
RU2010121862A (ru) 2011-12-10
CA2704207A1 (en) 2009-05-07
MX2010004548A (es) 2010-05-05

Similar Documents

Publication Publication Date Title
US8415118B2 (en) Porcine DC-SIGN, ICAM-3 and LSECtin and uses thereof
Huang et al. Porcine DC-SIGN: molecular cloning, gene structure, tissue distribution and binding characteristics
EP3735983A1 (en) Chimeric antigen receptor specific for tumor cells comprising an antigen binding domain specific for tspan8
CN115916833B (zh) 靶向b7h3的抗原结合多肽及其应用
JP2011206060A (ja) 可変性リンパ球受容体、その関連ポリペプチドおよび核酸、ならびにその使用
BR112019017008A2 (pt) anticorpo, ácido nucleico, vetor de expressão, célula hospedeira, imunoconjugado multifuncional, receptor de antígeno quimérico, vírus, célula imune modificada pelo receptor do antígeno quimérico, composição farmacêutica, kit, e, uso do anticorpo.
TW202342550A (zh) 靶向bcma和gprc5d的嵌合抗原受體及其應用
US20230210902A1 (en) Sars-cov-2-specific t cells
WO2023274385A1 (zh) 靶向her2的通用型car-t细胞及其制备方法
IL294960A (en) Delivery of sialidase to cancer cells, immune cells and the tumor microenvironment
NO341211B1 (no) In vitro fremgangsmåte for å fremme infeksjon i en virveldyrcelle med PRRSV og en fremgangsmåte for å måle tilbøyeligheten en testcellelinje har for å tillate PRRSV-infeksjon
CN118056008A (zh) 病毒载体生产系统
AU2013204023A1 (en) PORCINE DC-SIGN, ICAM AND LSECtin AND USES THEREOF
WO2021232050A1 (en) Natural killer cell immunotherapy for the treatment or prevention of sars-cov-2 infection
AU2020391178A1 (en) Immune cell delivery of sialidase to cancer cells, immune cells and the tumor microenvironment
CN120112650A (zh) 慢病毒配制品
JP2024527537A (ja) Gd2を標的とするユニバーサルcar-t細胞及びその製造方法並びに使用
JP2024527539A (ja) IL13Rα2を標的としたユニバーサルCAR-T細胞及びその製造方法と使用
JP2025525439A (ja) 操作されたナチュラルキラー(nk)細胞と抗体療法との組み合わせおよび関連する方法
WO2023274386A1 (zh) 靶向egfr的通用型car-t细胞及其制备方法
HK1157797A (en) Porcine dc-sign, icam-3 and lsectin and uses thereof
KR20250054790A (ko) 키메라 항원 수용체 도메인
HK40087387B (zh) 靶向b7h3的抗原结合多肽及其应用
HK40087387A (zh) 靶向b7h3的抗原结合多肽及其应用

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20111027

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20111027

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130702

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20131126

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20140120