KR20100087344A - 돼지 DC-SIGN, ICAM-3 및 LSECtin 및 이의 용도 - Google Patents

돼지 DC-SIGN, ICAM-3 및 LSECtin 및 이의 용도 Download PDF

Info

Publication number
KR20100087344A
KR20100087344A KR1020107011603A KR20107011603A KR20100087344A KR 20100087344 A KR20100087344 A KR 20100087344A KR 1020107011603 A KR1020107011603 A KR 1020107011603A KR 20107011603 A KR20107011603 A KR 20107011603A KR 20100087344 A KR20100087344 A KR 20100087344A
Authority
KR
South Korea
Prior art keywords
virus
sign
swine
cells
porcine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020107011603A
Other languages
English (en)
Korean (ko)
Inventor
야오웨이 황
샹-진 멍
Original Assignee
버지니아 테크 인터렉추얼 프라퍼티스, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 버지니아 테크 인터렉추얼 프라퍼티스, 인크. filed Critical 버지니아 테크 인터렉추얼 프라퍼티스, 인크.
Publication of KR20100087344A publication Critical patent/KR20100087344A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70525ICAM molecules, e.g. CD50, CD54, CD102
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056Lectin superfamily, e.g. CD23, CD72

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020107011603A 2007-10-29 2008-10-29 돼지 DC-SIGN, ICAM-3 및 LSECtin 및 이의 용도 Withdrawn KR20100087344A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80007P 2007-10-29 2007-10-29
US61/000,800 2007-10-29

Publications (1)

Publication Number Publication Date
KR20100087344A true KR20100087344A (ko) 2010-08-04

Family

ID=40591693

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107011603A Withdrawn KR20100087344A (ko) 2007-10-29 2008-10-29 돼지 DC-SIGN, ICAM-3 및 LSECtin 및 이의 용도

Country Status (14)

Country Link
US (1) US8415118B2 (https=)
EP (2) EP2662384A1 (https=)
JP (1) JP2011501958A (https=)
KR (1) KR20100087344A (https=)
CN (1) CN102066415A (https=)
AU (1) AU2008319384A1 (https=)
BR (1) BRPI0818477A2 (https=)
CA (1) CA2704207A1 (https=)
CO (1) CO6270367A2 (https=)
MX (1) MX2010004548A (https=)
NZ (1) NZ584893A (https=)
RU (1) RU2010121862A (https=)
WO (1) WO2009058285A2 (https=)
ZA (1) ZA201002773B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022050476A1 (ko) * 2020-09-04 2022-03-10 이형우 인간 면역결핍 바이러스 감염 또는 감염 질환의 치료용 조성물

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102947341B (zh) 2010-01-19 2018-07-06 哈佛大学校长及研究员协会 用于病原体检测和治疗的工程化调理素
WO2013012924A2 (en) 2011-07-18 2013-01-24 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
WO2013090806A2 (en) 2011-12-15 2013-06-20 Washington University Porcine knob xenotype chimeric adenoviral vector for dendritic cell infection
CN104284984B (zh) 2012-02-29 2017-10-13 哈佛大学校长及研究员协会 抗生素药敏性的快速测试
JP6254146B2 (ja) 2012-03-27 2017-12-27 エヌジーエム バイオファーマシューティカルス,インコーポレーテッド 代謝障害を治療するための組成物および方法
EP2976642A4 (en) 2013-03-15 2016-09-21 Harvard College METHOD AND COMPOSITIONS FOR IMPROVING THE DETECTION AND / OR RECORDING OF A TARGET UNIT
WO2014190040A1 (en) 2013-05-21 2014-11-27 President And Fellows Of Harvard College Engineered heme-binding compositions and uses thereof
EP3083658B1 (en) 2013-12-18 2019-05-08 President and Fellows of Harvard College Crp capture/detection of gram positive bacteria
MX370115B (es) 2014-07-30 2019-12-02 Ngm Biopharmaceuticals Inc Dímeros que comprenden dos polipéptidos, útiles en el tratamiento de trastornos metabólicos.
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
PL3212226T3 (pl) 2014-10-31 2020-11-02 Ngm Biopharmaceuticals, Inc. Kompozycje i sposoby stosowania w leczeniu zaburzeń metabolicznych
CN104749361B (zh) * 2015-01-21 2017-04-19 中国农业科学院哈尔滨兽医研究所 猪圆环病毒2型抗原捕获elisa试剂盒
CN105445457B (zh) * 2015-03-24 2017-08-11 中国农业科学院哈尔滨兽医研究所 检测猪圆环病毒2型Cap蛋白的单克隆抗体及试剂盒
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US10435457B2 (en) 2015-08-06 2019-10-08 President And Fellows Of Harvard College Microbe-binding molecules and uses thereof
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN106957847A (zh) * 2017-05-16 2017-07-18 吉林大学 有效抑制仔猪流行性腹泻病毒的siRNA及用途
CN107488635A (zh) * 2017-09-22 2017-12-19 中国人民解放军第三军医大学第三附属医院 单克隆细胞及其制备方法和用途
CN108893474B (zh) * 2018-02-07 2021-11-16 电子科技大学 草鱼细胞间粘附分子基因的分离和鉴定
CN108977444A (zh) * 2018-06-28 2018-12-11 西南大学 沉默荣昌猪CD14表达的siRNA及筛选方法与应用
CN109679952B (zh) * 2018-12-24 2022-04-15 西北农林科技大学 一种抗PRRSV感染的猪源miR-c89及其应用
CN109652384B (zh) * 2019-02-21 2021-10-26 昆明理工大学 一种体外培养戊型肝炎病毒的方法
CN109836478B (zh) * 2019-03-19 2022-06-14 扬州大学 非洲猪瘟病毒p11.5蛋白特异性多克隆抗体的制备方法及应用
CN109943536B (zh) * 2019-03-26 2021-09-14 昆明理工大学 一种戊型肝炎病毒的培养方法及其灭活疫苗的制备方法
CN111575409B (zh) * 2020-05-23 2023-04-18 黑龙江八一农垦大学 基于整合素配体识别肽抑制猪流行性腹泻病毒感染的研究方法
CN115725656B (zh) * 2021-09-01 2026-01-16 联邦生物科技(珠海横琴)有限公司 一种以细胞质rna病毒为载体递送干扰rna的方法
CN121454060A (zh) * 2026-01-05 2026-02-03 江苏立维斯德生物技术有限公司 一种基于免疫荧光法检测轮状病毒的方法、试剂盒及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2137547A1 (en) * 1992-06-11 1993-12-23 Daniel Meruelo Chimeric receptor polypeptides, human h13 proteins and uses thereof
GB9409768D0 (en) 1994-05-16 1994-07-06 Medical Res Council Trimerising polypeptides
US6146873A (en) 1994-11-10 2000-11-14 Baxter Aktiengesellschaft Production of orthomyxoviruses in monkey kidney cells using protein-free media
US6280953B1 (en) 1998-01-30 2001-08-28 Evolutionary Genomics, L.L.C. Methods to identify polynucleotide and polypeptide sequences which may be associated with physiological and medical conditions
JP2002543762A (ja) * 1999-03-25 2002-12-24 ブリストル−マイヤーズ スクイブ カンパニー ヒトclaxタンパク質およびその可溶性融合タンパク質をコードするdna分子
US6365156B1 (en) 1999-04-16 2002-04-02 Osel, Inc. Method for improving the half-life of soluble viral-specific ligands on mucosal membranes
EP1046651A1 (en) 1999-04-19 2000-10-25 Koninklijke Universiteit Nijmegen Composition and method for modulating dendritic cell-T interaction
US6391567B1 (en) 2000-03-02 2002-05-21 New York University Identifying compounds inhibiting DC-sign facilitation of HIV into cells
GB0318247D0 (en) * 2003-08-05 2003-09-10 Royal Veterinary College Antigen delivery system
BRPI0508762A (pt) 2004-04-16 2007-08-14 Genentech Inc método de aumento do esgotamento de células b em mamìferos, método de aumento da eficácia do esgotamento de células b, método de tratamento de malignidade ou neoplasma de células b, método de alìvio de disfunção autoimunológica regulada por células b, método de esgotamento das células b e composição

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022050476A1 (ko) * 2020-09-04 2022-03-10 이형우 인간 면역결핍 바이러스 감염 또는 감염 질환의 치료용 조성물

Also Published As

Publication number Publication date
JP2011501958A (ja) 2011-01-20
WO2009058285A9 (en) 2009-07-09
NZ584893A (en) 2012-08-31
US8415118B2 (en) 2013-04-09
US20100317054A1 (en) 2010-12-16
CO6270367A2 (es) 2011-04-20
ZA201002773B (en) 2011-10-26
EP2207798A2 (en) 2010-07-21
WO2009058285A2 (en) 2009-05-07
CA2704207A1 (en) 2009-05-07
EP2662384A1 (en) 2013-11-13
WO2009058285A3 (en) 2009-12-10
RU2010121862A (ru) 2011-12-10
AU2008319384A1 (en) 2009-05-07
CN102066415A (zh) 2011-05-18
MX2010004548A (es) 2010-05-05
BRPI0818477A2 (pt) 2015-04-14

Similar Documents

Publication Publication Date Title
KR20100087344A (ko) 돼지 DC-SIGN, ICAM-3 및 LSECtin 및 이의 용도
Huang et al. Porcine DC-SIGN: molecular cloning, gene structure, tissue distribution and binding characteristics
Calvert et al. CD163 expression confers susceptibility to porcine reproductive and respiratory syndrome viruses
JP6095616B2 (ja) 樹状細胞マーカーおよびその使用法
JP5600340B2 (ja) ウイルスに対する細胞性の許容性因子、および該因子の使用
CN115916833B (zh) 靶向b7h3的抗原结合多肽及其应用
CN108103099A (zh) 一种抗蓝耳病Marc-145细胞系及其制备方法和应用
CN111909966A (zh) 一种制备经修饰的免疫细胞的方法
Salgado et al. Genetically modified pigs lacking CD163 PSTII-domain-coding exon 13 are completely resistant to PRRSV infection
US20230210902A1 (en) Sars-cov-2-specific t cells
Young et al. Isolation of porcine reproductive and respiratory syndrome virus GP5-specific, neutralizing monoclonal antibodies from hyperimmune sows
CN117642510A (zh) 靶向her2的通用型car-t细胞及其制备方法
WO2024094165A1 (zh) 靶向b7h3的通用型car-t细胞及其制备方法和应用
AU2013204023A1 (en) PORCINE DC-SIGN, ICAM AND LSECtin AND USES THEREOF
WO2021232050A1 (en) Natural killer cell immunotherapy for the treatment or prevention of sars-cov-2 infection
JP2026502588A (ja) 膜固定サイトカイン、操作された免疫細胞、およびそれらの使用
KR20250060188A (ko) 조작된 자연 살해(nk) 세포 및 항체 요법의 조합 및 관련 방법
JP2025532635A (ja) 制御性t細胞を標的化して化膿性汗腺炎を治療するためのシトルリン化抗原特異的キメラ抗原受容体
WO2023274386A1 (zh) 靶向egfr的通用型car-t细胞及其制备方法
HK1157797A (en) Porcine dc-sign, icam-3 and lsectin and uses thereof
WO2023274387A1 (zh) 靶向gd2的通用型car-t细胞及其制备方法和应用
Mondal et al. Development and characterization of a synthetic infectious cDNA clone of the virulent Bucyrus strain of equine arteritis virus expressing mCherry (red fluorescent protein)
JP2024527539A (ja) IL13Rα2を標的としたユニバーサルCAR-T細胞及びその製造方法と使用
Zhu et al. Influence of polymorphism in dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related (DC-SIGNR) gene on HIV-1 trans-infection
HK40087387B (zh) 靶向b7h3的抗原结合多肽及其应用

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20100527

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid