CO6270367A2 - Genes de dc-sign icam-3 y lsectin porcinas y usos de los mismos - Google Patents

Genes de dc-sign icam-3 y lsectin porcinas y usos de los mismos

Info

Publication number
CO6270367A2
CO6270367A2 CO10050942A CO10050942A CO6270367A2 CO 6270367 A2 CO6270367 A2 CO 6270367A2 CO 10050942 A CO10050942 A CO 10050942A CO 10050942 A CO10050942 A CO 10050942A CO 6270367 A2 CO6270367 A2 CO 6270367A2
Authority
CO
Colombia
Prior art keywords
porcine
new
lsectin
icam
sign
Prior art date
Application number
CO10050942A
Other languages
English (en)
Inventor
Yaowei Huang
Xiang-Jin Meng
Original Assignee
Virginia Tech Intell Prop
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virginia Tech Intell Prop filed Critical Virginia Tech Intell Prop
Publication of CO6270367A2 publication Critical patent/CO6270367A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La presente invencion se refiere a la clonacion, identificacion y caracterizacion de las secuencias genomicas ·nicas y completas que codifican para las nuevas proteinas de DC-SING y LSECtin porcinas, incluyendo las nuevas secuencias de nucleotidos del cDNA de longitud completa los genes tanto para el gen de pDC-SIGN como para pLSECtin. También se proporcionan molécula de acido nucleico que codifican para las recién descubiertas isoformas de ICAM-3 porcinas de células dendriticas derivadas en monocitos porcinos y el uso de las mismas. Especificamente, la invencion se refiere a una molécula aislada de acido nucleico que comprende una secuencia de nucleotidos que codifica para una o mas de DC-SIGN porcina, ICAM-3 porcina, LSECtin porcina, un complemento de la secuencia de nucleotidos o una porcion funcional, definida de la secuencia de nucleotidos o un producto de fusion de proteina enlazado a una proteina que puede ser de origen porcino o humano. Adicionalmente se describen en la presente métodos para aislar y donar los nuevos genes porcinos y para usar las nuevas secuencias de nucleotidos en métodos mejorados para propagar virus, particularmente virus envuelto. La invencion incluye ademas nuevas células transfectadas o lineas celulares que puedan expresar de manera estable las proteinas porcinas, nuevos anticuerpos y similares.
CO10050942A 2007-10-29 2010-04-29 Genes de dc-sign icam-3 y lsectin porcinas y usos de los mismos CO6270367A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80007P 2007-10-29 2007-10-29

Publications (1)

Publication Number Publication Date
CO6270367A2 true CO6270367A2 (es) 2011-04-20

Family

ID=40591693

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10050942A CO6270367A2 (es) 2007-10-29 2010-04-29 Genes de dc-sign icam-3 y lsectin porcinas y usos de los mismos

Country Status (14)

Country Link
US (1) US8415118B2 (es)
EP (2) EP2662384A1 (es)
JP (1) JP2011501958A (es)
KR (1) KR20100087344A (es)
CN (1) CN102066415A (es)
AU (1) AU2008319384A1 (es)
BR (1) BRPI0818477A2 (es)
CA (1) CA2704207A1 (es)
CO (1) CO6270367A2 (es)
MX (1) MX2010004548A (es)
NZ (1) NZ584893A (es)
RU (1) RU2010121862A (es)
WO (1) WO2009058285A2 (es)
ZA (1) ZA201002773B (es)

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CA2842321C (en) 2011-07-18 2022-05-03 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
US9267153B2 (en) 2011-12-15 2016-02-23 Washington University Porcine knob xenotype chimeric adenoviral vector for dendritic cell infection
AU2013225823A1 (en) 2012-02-29 2014-09-18 President And Fellows Of Harvard College Rapid antibiotic susceptibility testing
EP2830646B1 (en) 2012-03-27 2018-03-07 NGM Biopharmaceuticals, Inc. Compositions and methods of use for treating metabolic disorders
EP2976642A4 (en) 2013-03-15 2016-09-21 Harvard College METHODS AND COMPOSITIONS FOR IMPROVING THE DETECTION AND / OR CAPTURE OF A TARGET ENTITY
AU2014268603B2 (en) 2013-05-21 2018-03-22 President And Fellows Of Harvard College Engineered heme-binding compositions and uses thereof
EP3083658B1 (en) 2013-12-18 2019-05-08 President and Fellows of Harvard College Crp capture/detection of gram positive bacteria
KR20170065026A (ko) * 2014-07-30 2017-06-12 엔지엠 바이오파마슈티컬스, 아이엔씨. 대사 장애 치료용으로 이용되는 조성물 및 방법
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
MY186702A (en) 2014-10-31 2021-08-11 Ngm Biopharmaceuticals Inc Compositions and methods of use for treating metabolic disorders
CN104749361B (zh) * 2015-01-21 2017-04-19 中国农业科学院哈尔滨兽医研究所 猪圆环病毒2型抗原捕获elisa试剂盒
CN105445457B (zh) * 2015-03-24 2017-08-11 中国农业科学院哈尔滨兽医研究所 检测猪圆环病毒2型Cap蛋白的单克隆抗体及试剂盒
EP3331549B1 (en) 2015-08-06 2020-12-23 President and Fellows of Harvard College Improved microbe-binding molecules and uses thereof
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN106957847A (zh) * 2017-05-16 2017-07-18 吉林大学 有效抑制仔猪流行性腹泻病毒的siRNA及用途
CN107488635A (zh) * 2017-09-22 2017-12-19 中国人民解放军第三军医大学第三附属医院 单克隆细胞及其制备方法和用途
CN108893474B (zh) * 2018-02-07 2021-11-16 电子科技大学 草鱼细胞间粘附分子基因的分离和鉴定
CN108977444A (zh) * 2018-06-28 2018-12-11 西南大学 沉默荣昌猪CD14表达的siRNA及筛选方法与应用
CN109679952B (zh) * 2018-12-24 2022-04-15 西北农林科技大学 一种抗PRRSV感染的猪源miR-c89及其应用
CN109652384B (zh) * 2019-02-21 2021-10-26 昆明理工大学 一种体外培养戊型肝炎病毒的方法
CN109836478B (zh) * 2019-03-19 2022-06-14 扬州大学 非洲猪瘟病毒p11.5蛋白特异性多克隆抗体的制备方法及应用
CN109943536B (zh) * 2019-03-26 2021-09-14 昆明理工大学 一种戊型肝炎病毒的培养方法及其灭活疫苗的制备方法
CN111575409B (zh) * 2020-05-23 2023-04-18 黑龙江八一农垦大学 基于整合素配体识别肽抑制猪流行性腹泻病毒感染的研究方法
WO2022050476A1 (ko) * 2020-09-04 2022-03-10 이형우 인간 면역결핍 바이러스 감염 또는 감염 질환의 치료용 조성물

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Also Published As

Publication number Publication date
WO2009058285A2 (en) 2009-05-07
MX2010004548A (es) 2010-05-05
BRPI0818477A2 (pt) 2015-04-14
US8415118B2 (en) 2013-04-09
JP2011501958A (ja) 2011-01-20
NZ584893A (en) 2012-08-31
ZA201002773B (en) 2011-10-26
WO2009058285A3 (en) 2009-12-10
WO2009058285A9 (en) 2009-07-09
US20100317054A1 (en) 2010-12-16
KR20100087344A (ko) 2010-08-04
CA2704207A1 (en) 2009-05-07
CN102066415A (zh) 2011-05-18
RU2010121862A (ru) 2011-12-10
EP2207798A2 (en) 2010-07-21
AU2008319384A1 (en) 2009-05-07
EP2662384A1 (en) 2013-11-13

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