JP2011500818A5 - - Google Patents

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Publication number
JP2011500818A5
JP2011500818A5 JP2010531133A JP2010531133A JP2011500818A5 JP 2011500818 A5 JP2011500818 A5 JP 2011500818A5 JP 2010531133 A JP2010531133 A JP 2010531133A JP 2010531133 A JP2010531133 A JP 2010531133A JP 2011500818 A5 JP2011500818 A5 JP 2011500818A5
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JP
Japan
Prior art keywords
compound according
compound
formula
alkyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010531133A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011500818A (ja
JP5410438B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/080063 external-priority patent/WO2009055289A2/en
Publication of JP2011500818A publication Critical patent/JP2011500818A/ja
Publication of JP2011500818A5 publication Critical patent/JP2011500818A5/ja
Application granted granted Critical
Publication of JP5410438B2 publication Critical patent/JP5410438B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010531133A 2007-10-23 2008-10-16 治療用置換ラクタム類 Expired - Fee Related JP5410438B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US98191807P 2007-10-23 2007-10-23
US60/981,918 2007-10-23
US98483807P 2007-11-02 2007-11-02
US60/984,838 2007-11-02
PCT/US2008/080063 WO2009055289A2 (en) 2007-10-23 2008-10-16 Therapeutic substituted lactams

Publications (3)

Publication Number Publication Date
JP2011500818A JP2011500818A (ja) 2011-01-06
JP2011500818A5 true JP2011500818A5 (enExample) 2011-12-08
JP5410438B2 JP5410438B2 (ja) 2014-02-05

Family

ID=40521508

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010531133A Expired - Fee Related JP5410438B2 (ja) 2007-10-23 2008-10-16 治療用置換ラクタム類

Country Status (12)

Country Link
US (1) US7998998B2 (enExample)
EP (1) EP2215084B1 (enExample)
JP (1) JP5410438B2 (enExample)
KR (1) KR20100086485A (enExample)
CN (1) CN101868455B (enExample)
AU (1) AU2008317107B2 (enExample)
BR (1) BRPI0820410A2 (enExample)
CA (1) CA2703479C (enExample)
IL (1) IL205278A0 (enExample)
MX (1) MX2010004487A (enExample)
NZ (1) NZ585103A (enExample)
WO (1) WO2009055289A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008144623A1 (en) * 2007-05-23 2008-11-27 Allergan, Inc. Cyclic lactams for the treatment of glaucoma or elevated intraocular pressure
NZ704171A (en) 2012-07-19 2017-10-27 Cayman Chemical Co Inc Difluorolactam compositions for ep4-mediated osteo related diseases and conditions
WO2014031581A1 (en) * 2012-08-21 2014-02-27 Allergan, Inc. Process for the synthesis of substituted gamma lactams
CN107312039B (zh) 2012-08-30 2019-06-25 江苏豪森药业集团有限公司 一种替诺福韦前药的制备方法
EA201591793A1 (ru) 2013-03-15 2016-01-29 Кайман Кемикал Компани, Инк. Лактамные соединения в качестве селективных агонистов ep4-рецепторов для применения при лечении опосредованных ep4 заболеваний и состояний
US9676712B2 (en) 2013-03-15 2017-06-13 Cayman Chemical Company, Inc. Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions
US9914725B2 (en) 2013-03-15 2018-03-13 Cayman Chemical Company, Inc. Methods of synthesizing a difluorolactam analog
CA2910398A1 (en) 2013-07-19 2015-01-22 Cayman Chemical Company, Inc. Methods, systems, and compositions for promoting bone growth
US9540357B1 (en) 2014-07-31 2017-01-10 Allergan, Inc. 15-aryl prostaglandins as EP4 agonists, and methods of use thereof
KR102877633B1 (ko) 2021-09-01 2025-10-28 에스케이하이닉스 주식회사 반도체 웨이퍼의 불량 분석 방법 및 그 시스템

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4035961A1 (de) * 1990-11-02 1992-05-07 Thomae Gmbh Dr K Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
KR20040015364A (ko) * 2001-07-16 2004-02-18 에프. 호프만-라 로슈 아게 Ep4 수용체 작용물질로서의 프로스타글란딘 유사체
AU2004215428B2 (en) * 2003-02-26 2009-08-27 Sugen LLC Aminoheteroaryl compounds as protein kinase inhibitors
MXPA06012932A (es) * 2004-05-07 2007-01-26 Janssen Pharmaceutica Nv Derivados de pirrolidin-2-ona y piperidin-2-ona como inhibidores de 11-beta hidroxiesteroide deshidrogenasa.
WO2007108360A1 (ja) * 2006-03-17 2007-09-27 Intellectual Property Bank Corp. 細径盲管を用いた表面増強ラマン散乱による物質検知方法および物質検知装置、複数物質検知デバイス、盲管
CN101657445B (zh) * 2007-02-15 2013-06-05 阿勒根公司 治疗青光眼或眼内压升高的γ内酰胺

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