JP2011500818A5 - - Google Patents

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Publication number
JP2011500818A5
JP2011500818A5 JP2010531133A JP2010531133A JP2011500818A5 JP 2011500818 A5 JP2011500818 A5 JP 2011500818A5 JP 2010531133 A JP2010531133 A JP 2010531133A JP 2010531133 A JP2010531133 A JP 2010531133A JP 2011500818 A5 JP2011500818 A5 JP 2011500818A5
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JP
Japan
Prior art keywords
compound according
compound
formula
alkyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010531133A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011500818A (ja
JP5410438B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/080063 external-priority patent/WO2009055289A2/en
Publication of JP2011500818A publication Critical patent/JP2011500818A/ja
Publication of JP2011500818A5 publication Critical patent/JP2011500818A5/ja
Application granted granted Critical
Publication of JP5410438B2 publication Critical patent/JP5410438B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010531133A 2007-10-23 2008-10-16 治療用置換ラクタム類 Expired - Fee Related JP5410438B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US98191807P 2007-10-23 2007-10-23
US60/981,918 2007-10-23
US98483807P 2007-11-02 2007-11-02
US60/984,838 2007-11-02
PCT/US2008/080063 WO2009055289A2 (en) 2007-10-23 2008-10-16 Therapeutic substituted lactams

Publications (3)

Publication Number Publication Date
JP2011500818A JP2011500818A (ja) 2011-01-06
JP2011500818A5 true JP2011500818A5 (enExample) 2011-12-08
JP5410438B2 JP5410438B2 (ja) 2014-02-05

Family

ID=40521508

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010531133A Expired - Fee Related JP5410438B2 (ja) 2007-10-23 2008-10-16 治療用置換ラクタム類

Country Status (12)

Country Link
US (1) US7998998B2 (enExample)
EP (1) EP2215084B1 (enExample)
JP (1) JP5410438B2 (enExample)
KR (1) KR20100086485A (enExample)
CN (1) CN101868455B (enExample)
AU (1) AU2008317107B2 (enExample)
BR (1) BRPI0820410A2 (enExample)
CA (1) CA2703479C (enExample)
IL (1) IL205278A0 (enExample)
MX (1) MX2010004487A (enExample)
NZ (1) NZ585103A (enExample)
WO (1) WO2009055289A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5524047B2 (ja) * 2007-05-23 2014-06-18 アラーガン インコーポレイテッド 緑内障および眼圧上昇の治療用環状ラクタム類
US9440919B2 (en) 2012-07-19 2016-09-13 Cayman Chemical Company, Inc. Difluorolactam compositions for EP4-mediated osteo related diseases and conditions
US8962863B2 (en) * 2012-08-21 2015-02-24 Allergan, Inc. Process for the synthesis of substituted gamma lactams
CN103665043B (zh) 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 一种替诺福韦前药及其在医药上的应用
JP6368351B2 (ja) 2013-03-15 2018-08-01 ケイマン ケミカル カンパニー, インコーポレーテッド ジフルオロラクタムアナログを合成する方法
ES2635635T3 (es) 2013-03-15 2017-10-04 Cayman Chemical Company, Incorporated Compuestos de difluorolactama como agonistas selectivos del receptor EP4 para su uso en el tratamiento de enfermedades y afecciones mediadas por EP4
WO2014144610A1 (en) 2013-03-15 2014-09-18 Cayman Chemical Company, Inc. Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions
EP3021879A2 (en) 2013-07-19 2016-05-25 Cayman Chemical Company, Incorporated Methods, systems, and compositions for promoting bone growth
US9540357B1 (en) 2014-07-31 2017-01-10 Allergan, Inc. 15-aryl prostaglandins as EP4 agonists, and methods of use thereof
KR102877633B1 (ko) 2021-09-01 2025-10-28 에스케이하이닉스 주식회사 반도체 웨이퍼의 불량 분석 방법 및 그 시스템

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4035961A1 (de) * 1990-11-02 1992-05-07 Thomae Gmbh Dr K Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
RU2288913C2 (ru) * 2001-07-16 2006-12-10 Ф.Хоффманн-Ля Рош Аг Аналоги простагландинов, способ их получения и фармацевтическая композиция, обладающая селективной агонистической активностью в отношении рецептора ep4
GEP20084341B (en) * 2003-02-26 2008-03-25 Sugen Inc Aminoheteroaryl compounds as protein kinase inhibitors
WO2005108360A1 (en) * 2004-05-07 2005-11-17 Janssen Pharmaceutica N.V. Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
WO2007108360A1 (ja) * 2006-03-17 2007-09-27 Intellectual Property Bank Corp. 細径盲管を用いた表面増強ラマン散乱による物質検知方法および物質検知装置、複数物質検知デバイス、盲管
BRPI0807600A2 (pt) * 2007-02-15 2014-07-22 Allergan Inc Gama-lactamas para o tratamento de glaucoma ou pressão intraocular elevada

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