JP2011500818A5 - - Google Patents

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Publication number
JP2011500818A5
JP2011500818A5 JP2010531133A JP2010531133A JP2011500818A5 JP 2011500818 A5 JP2011500818 A5 JP 2011500818A5 JP 2010531133 A JP2010531133 A JP 2010531133A JP 2010531133 A JP2010531133 A JP 2010531133A JP 2011500818 A5 JP2011500818 A5 JP 2011500818A5
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JP
Japan
Prior art keywords
compound according
compound
formula
alkyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010531133A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011500818A (ja
JP5410438B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/080063 external-priority patent/WO2009055289A2/en
Publication of JP2011500818A publication Critical patent/JP2011500818A/ja
Publication of JP2011500818A5 publication Critical patent/JP2011500818A5/ja
Application granted granted Critical
Publication of JP5410438B2 publication Critical patent/JP5410438B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010531133A 2007-10-23 2008-10-16 治療用置換ラクタム類 Expired - Fee Related JP5410438B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US98191807P 2007-10-23 2007-10-23
US60/981,918 2007-10-23
US98483807P 2007-11-02 2007-11-02
US60/984,838 2007-11-02
PCT/US2008/080063 WO2009055289A2 (en) 2007-10-23 2008-10-16 Therapeutic substituted lactams

Publications (3)

Publication Number Publication Date
JP2011500818A JP2011500818A (ja) 2011-01-06
JP2011500818A5 true JP2011500818A5 (enExample) 2011-12-08
JP5410438B2 JP5410438B2 (ja) 2014-02-05

Family

ID=40521508

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010531133A Expired - Fee Related JP5410438B2 (ja) 2007-10-23 2008-10-16 治療用置換ラクタム類

Country Status (12)

Country Link
US (1) US7998998B2 (enExample)
EP (1) EP2215084B1 (enExample)
JP (1) JP5410438B2 (enExample)
KR (1) KR20100086485A (enExample)
CN (1) CN101868455B (enExample)
AU (1) AU2008317107B2 (enExample)
BR (1) BRPI0820410A2 (enExample)
CA (1) CA2703479C (enExample)
IL (1) IL205278A0 (enExample)
MX (1) MX2010004487A (enExample)
NZ (1) NZ585103A (enExample)
WO (1) WO2009055289A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5524047B2 (ja) * 2007-05-23 2014-06-18 アラーガン インコーポレイテッド 緑内障および眼圧上昇の治療用環状ラクタム類
CN107802623B (zh) 2012-07-19 2020-10-30 开曼化学股份有限公司 用于ep4介导的骨相关疾病和病症的二氟内酰胺组合物
US8962863B2 (en) * 2012-08-21 2015-02-24 Allergan, Inc. Process for the synthesis of substituted gamma lactams
CN107312039B (zh) 2012-08-30 2019-06-25 江苏豪森药业集团有限公司 一种替诺福韦前药的制备方法
BR112015023080A2 (pt) 2013-03-15 2017-07-18 Cayman Chemical Co Inc composto, composição farmacêutica, e, método para tratamento de doenças
JP6368351B2 (ja) 2013-03-15 2018-08-01 ケイマン ケミカル カンパニー, インコーポレーテッド ジフルオロラクタムアナログを合成する方法
WO2014144610A1 (en) 2013-03-15 2014-09-18 Cayman Chemical Company, Inc. Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions
WO2015009991A2 (en) 2013-07-19 2015-01-22 Cayman Chemical Company, Inc. Methods, systems, and compositions for promoting bone growth
US9540357B1 (en) 2014-07-31 2017-01-10 Allergan, Inc. 15-aryl prostaglandins as EP4 agonists, and methods of use thereof
KR102877633B1 (ko) 2021-09-01 2025-10-28 에스케이하이닉스 주식회사 반도체 웨이퍼의 불량 분석 방법 및 그 시스템

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4035961A1 (de) * 1990-11-02 1992-05-07 Thomae Gmbh Dr K Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
WO2003008377A1 (en) * 2001-07-16 2003-01-30 F. Hoffmann-La Roche Ag Prostaglandin analogues_as ep4 receptor agonists
MXPA05009063A (es) * 2003-02-26 2005-12-12 Sugen Inc Compuestos de aminoheteroarilo como inhibidores de proteina cinasa.
NZ551077A (en) 2004-05-07 2009-05-31 Janssen Pharmaceutica Nv Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
WO2007108360A1 (ja) * 2006-03-17 2007-09-27 Intellectual Property Bank Corp. 細径盲管を用いた表面増強ラマン散乱による物質検知方法および物質検知装置、複数物質検知デバイス、盲管
MX2009008734A (es) * 2007-02-15 2009-08-25 Allergan Inc Gamma lactamas para el tratamiento de glaucoma o hipertension intraocular.

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