JP2011500818A5 - - Google Patents

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Publication number
JP2011500818A5
JP2011500818A5 JP2010531133A JP2010531133A JP2011500818A5 JP 2011500818 A5 JP2011500818 A5 JP 2011500818A5 JP 2010531133 A JP2010531133 A JP 2010531133A JP 2010531133 A JP2010531133 A JP 2010531133A JP 2011500818 A5 JP2011500818 A5 JP 2011500818A5
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JP
Japan
Prior art keywords
compound according
compound
formula
alkyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010531133A
Other languages
English (en)
Japanese (ja)
Other versions
JP5410438B2 (ja
JP2011500818A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/080063 external-priority patent/WO2009055289A2/en
Publication of JP2011500818A publication Critical patent/JP2011500818A/ja
Publication of JP2011500818A5 publication Critical patent/JP2011500818A5/ja
Application granted granted Critical
Publication of JP5410438B2 publication Critical patent/JP5410438B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010531133A 2007-10-23 2008-10-16 治療用置換ラクタム類 Expired - Fee Related JP5410438B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US98191807P 2007-10-23 2007-10-23
US60/981,918 2007-10-23
US98483807P 2007-11-02 2007-11-02
US60/984,838 2007-11-02
PCT/US2008/080063 WO2009055289A2 (en) 2007-10-23 2008-10-16 Therapeutic substituted lactams

Publications (3)

Publication Number Publication Date
JP2011500818A JP2011500818A (ja) 2011-01-06
JP2011500818A5 true JP2011500818A5 (enExample) 2011-12-08
JP5410438B2 JP5410438B2 (ja) 2014-02-05

Family

ID=40521508

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010531133A Expired - Fee Related JP5410438B2 (ja) 2007-10-23 2008-10-16 治療用置換ラクタム類

Country Status (12)

Country Link
US (1) US7998998B2 (enExample)
EP (1) EP2215084B1 (enExample)
JP (1) JP5410438B2 (enExample)
KR (1) KR20100086485A (enExample)
CN (1) CN101868455B (enExample)
AU (1) AU2008317107B2 (enExample)
BR (1) BRPI0820410A2 (enExample)
CA (1) CA2703479C (enExample)
IL (1) IL205278A0 (enExample)
MX (1) MX2010004487A (enExample)
NZ (1) NZ585103A (enExample)
WO (1) WO2009055289A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2155733T3 (da) * 2007-05-23 2012-10-29 Allergan Inc Cykliske lactamer til behandling af glaukom eller forhøjet intraokulært tryk
HUE031885T2 (en) 2012-07-19 2017-08-28 Cayman Chemical Co Inc Difluoro lactam preparations for EP4-mediated osteo-related diseases and conditions
KR102221534B1 (ko) * 2012-08-21 2021-02-26 알레간 인코포레이티드 치환된 감마 락탐의 합성을 위한 공정
CN103665043B (zh) 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 一种替诺福韦前药及其在医药上的应用
ES2635635T3 (es) 2013-03-15 2017-10-04 Cayman Chemical Company, Incorporated Compuestos de difluorolactama como agonistas selectivos del receptor EP4 para su uso en el tratamiento de enfermedades y afecciones mediadas por EP4
US9676712B2 (en) 2013-03-15 2017-06-13 Cayman Chemical Company, Inc. Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions
WO2014144500A2 (en) 2013-03-15 2014-09-18 Cayman Chemical Company, Inc. Methods of synthesizing a difluorolactam analog
KR20160048054A (ko) 2013-07-19 2016-05-03 카이맨 케미칼 컴파니 인코포레이티드 골 성장의 촉진을 위한 방법, 시스템 및 조성물
US9540357B1 (en) 2014-07-31 2017-01-10 Allergan, Inc. 15-aryl prostaglandins as EP4 agonists, and methods of use thereof
KR102877633B1 (ko) 2021-09-01 2025-10-28 에스케이하이닉스 주식회사 반도체 웨이퍼의 불량 분석 방법 및 그 시스템

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4035961A1 (de) * 1990-11-02 1992-05-07 Thomae Gmbh Dr K Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
ES2254726T3 (es) 2001-07-16 2006-06-16 F. Hoffmann-La Roche Ag Analogos de prostaglandina como agonistas receptores de ep4.
RS53118B (sr) * 2003-02-26 2014-06-30 Sugen Inc. Aminoheteroaril jedinjenja kao inhibitori protein kinaze
CN101001836B (zh) 2004-05-07 2010-12-22 詹森药业有限公司 作为11-β羟基类固醇脱氢酶抑制剂的吡咯烷-2-酮和哌啶-2-酮衍生物
WO2007108360A1 (ja) * 2006-03-17 2007-09-27 Intellectual Property Bank Corp. 細径盲管を用いた表面増強ラマン散乱による物質検知方法および物質検知装置、複数物質検知デバイス、盲管
CA2678191A1 (en) * 2007-02-15 2008-08-21 Allergan, Inc. Gamma-lactams for the treatment of glaucoma or elevated intraocular pressure

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