JP2009543795A5 - - Google Patents
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- JP2009543795A5 JP2009543795A5 JP2009519615A JP2009519615A JP2009543795A5 JP 2009543795 A5 JP2009543795 A5 JP 2009543795A5 JP 2009519615 A JP2009519615 A JP 2009519615A JP 2009519615 A JP2009519615 A JP 2009519615A JP 2009543795 A5 JP2009543795 A5 JP 2009543795A5
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- JP
- Japan
- Prior art keywords
- alkyl
- carbon atoms
- compound according
- hydrogen
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80694706P | 2006-07-11 | 2006-07-11 | |
| US60/806,947 | 2006-07-11 | ||
| PCT/US2007/073012 WO2008008718A2 (en) | 2006-07-11 | 2007-07-09 | Cyclopentane derivatives as antiglaucoma agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009543795A JP2009543795A (ja) | 2009-12-10 |
| JP2009543795A5 true JP2009543795A5 (enExample) | 2010-08-26 |
| JP5570807B2 JP5570807B2 (ja) | 2014-08-13 |
Family
ID=38728718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009519615A Expired - Fee Related JP5570807B2 (ja) | 2006-07-11 | 2007-07-09 | 抗緑内障薬としてのシクロペンタン誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7592366B2 (enExample) |
| EP (1) | EP2043993B1 (enExample) |
| JP (1) | JP5570807B2 (enExample) |
| AU (1) | AU2007272617B2 (enExample) |
| BR (1) | BRPI0714885B8 (enExample) |
| CA (1) | CA2657719C (enExample) |
| DK (1) | DK2043993T3 (enExample) |
| ES (1) | ES2549863T3 (enExample) |
| PL (1) | PL2043993T3 (enExample) |
| WO (1) | WO2008008718A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080015219A1 (en) * | 2006-07-11 | 2008-01-17 | Allergan, Inc. | Therapeutic compounds |
| WO2008144623A1 (en) * | 2007-05-23 | 2008-11-27 | Allergan, Inc. | Cyclic lactams for the treatment of glaucoma or elevated intraocular pressure |
| DK2170345T3 (da) * | 2007-07-03 | 2013-05-13 | Allergan Inc | Terapeutiske substituerede cyclopentaner til reduktion af intraokulært tryk |
| US7947732B2 (en) * | 2007-07-13 | 2011-05-24 | Allergan, Inc. | Therapeutic substituted chlorocyclopentanols |
| US8299068B2 (en) | 2010-01-29 | 2012-10-30 | Allergan, Inc. | Therapeutically active cyclopentanes |
| CN104684904B (zh) * | 2012-08-27 | 2017-10-13 | 阿勒根公司 | 通过使用β‑氯环戊烷的亲水性酯前药减轻中央角膜增厚 |
| US9090595B2 (en) | 2012-08-27 | 2015-07-28 | Allergan, Inc. | Reduced central corneal thickening by use of hydrophilic ester prodrugs of beta-chlorocyclopentanes |
| ES2717481T3 (es) * | 2014-02-20 | 2019-06-21 | Allergan Inc | Engrosamiento corneal central reducido mediante el uso de profármacos de ésteres hidrófilos de beta-clorociclopentanos |
| EP3112362B1 (en) * | 2014-02-27 | 2018-09-26 | ONO Pharmaceutical Co., Ltd. | Compound exhibiting selective ep2 agonist activity |
| WO2015179815A1 (en) | 2014-05-22 | 2015-11-26 | Allergan, Inc. | Amidoalkylenyl and amidoaryl esters, compositions thereof, and methods for their use |
| CN106458859B (zh) | 2014-06-06 | 2019-08-30 | 阿勒根公司 | 作为治疗性化合物的新型ep4激动剂 |
| US9540357B1 (en) | 2014-07-31 | 2017-01-10 | Allergan, Inc. | 15-aryl prostaglandins as EP4 agonists, and methods of use thereof |
| JP6662864B2 (ja) | 2014-10-02 | 2020-03-11 | アラーガン、インコーポレイテッドAllergan,Incorporated | ガンマ−ラクタムのエステルプロドラッグ及びそれらの使用 |
| EP3327018B1 (en) | 2015-07-23 | 2020-11-25 | ONO Pharmaceutical Co., Ltd. | 2-(octahydrocyclopenta[b]pyran-2-yl)1,3-thiazole-4-carboxylic acid derivatives and related compounds as ep2 agonists with intraocular pressure lowering activity |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3980700A (en) * | 1971-10-07 | 1976-09-14 | G. D. Searle & Co. | Prostaglandin intermediates and optically active isomers thereof |
| DE2346706A1 (de) * | 1973-09-17 | 1975-04-03 | Hoechst Ag | Neue, nicht natuerlich vorkommende analoga von prostansaeuren und verfahren zu ihrer herstellung |
| US4073799A (en) * | 1975-02-27 | 1978-02-14 | (Zaidanhojin) Sagami Chemical Research Center | Process for producing 3-formylcyclopentanone derivatives |
| US4094886A (en) * | 1976-03-01 | 1978-06-13 | (Zaidanhojin) Sagami Chemical Research Center | Process for producing allyl alcohol derivatives useful in prostaglandin synthesis |
| US5151444B1 (en) * | 1987-09-18 | 1999-07-06 | R Tech Ueno Ltd | Ocular hypotensive agents |
| US5688819A (en) * | 1992-09-21 | 1997-11-18 | Allergan | Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| US5352708A (en) * | 1992-09-21 | 1994-10-04 | Allergan, Inc. | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
| JPH07238068A (ja) * | 1994-02-24 | 1995-09-12 | Taisho Pharmaceut Co Ltd | プロスタグランジンe1類縁体 |
| AU7349298A (en) * | 1997-06-23 | 1999-01-04 | Pfizer Inc. | Prostaglandin agonists |
| JP2001527063A (ja) * | 1998-12-24 | 2001-12-25 | 小野薬品工業株式会社 | ω−シクロアルキル−プロスタグランジンE2誘導体 |
| KR20040023707A (ko) * | 2001-07-31 | 2004-03-18 | 수캄포 아게 | 안내압항진 및 녹내장의 치료 |
| WO2007149829A2 (en) * | 2006-06-20 | 2007-12-27 | Allergan, Inc. | Therapeutic compounds |
| ES2447065T3 (es) * | 2006-07-10 | 2014-03-11 | Allergan, Inc. | Derivados de ciclopentano sustituidos como agentes terapeuticos |
| US20080015219A1 (en) * | 2006-07-11 | 2008-01-17 | Allergan, Inc. | Therapeutic compounds |
-
2007
- 2007-07-09 EP EP07812705.7A patent/EP2043993B1/en active Active
- 2007-07-09 BR BRPI0714885A patent/BRPI0714885B8/pt not_active IP Right Cessation
- 2007-07-09 ES ES07812705.7T patent/ES2549863T3/es active Active
- 2007-07-09 WO PCT/US2007/073012 patent/WO2008008718A2/en not_active Ceased
- 2007-07-09 JP JP2009519615A patent/JP5570807B2/ja not_active Expired - Fee Related
- 2007-07-09 DK DK07812705.7T patent/DK2043993T3/en active
- 2007-07-09 AU AU2007272617A patent/AU2007272617B2/en not_active Ceased
- 2007-07-09 CA CA2657719A patent/CA2657719C/en not_active Expired - Fee Related
- 2007-07-09 PL PL07812705T patent/PL2043993T3/pl unknown
- 2007-07-10 US US11/775,283 patent/US7592366B2/en active Active
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