JP2009543795A5 - - Google Patents

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Publication number
JP2009543795A5
JP2009543795A5 JP2009519615A JP2009519615A JP2009543795A5 JP 2009543795 A5 JP2009543795 A5 JP 2009543795A5 JP 2009519615 A JP2009519615 A JP 2009519615A JP 2009519615 A JP2009519615 A JP 2009519615A JP 2009543795 A5 JP2009543795 A5 JP 2009543795A5
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JP
Japan
Prior art keywords
alkyl
carbon atoms
compound according
hydrogen
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009519615A
Other languages
English (en)
Japanese (ja)
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JP2009543795A (ja
JP5570807B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/073012 external-priority patent/WO2008008718A2/en
Publication of JP2009543795A publication Critical patent/JP2009543795A/ja
Publication of JP2009543795A5 publication Critical patent/JP2009543795A5/ja
Application granted granted Critical
Publication of JP5570807B2 publication Critical patent/JP5570807B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009519615A 2006-07-11 2007-07-09 抗緑内障薬としてのシクロペンタン誘導体 Expired - Fee Related JP5570807B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80694706P 2006-07-11 2006-07-11
US60/806,947 2006-07-11
PCT/US2007/073012 WO2008008718A2 (en) 2006-07-11 2007-07-09 Cyclopentane derivatives as antiglaucoma agents

Publications (3)

Publication Number Publication Date
JP2009543795A JP2009543795A (ja) 2009-12-10
JP2009543795A5 true JP2009543795A5 (enExample) 2010-08-26
JP5570807B2 JP5570807B2 (ja) 2014-08-13

Family

ID=38728718

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009519615A Expired - Fee Related JP5570807B2 (ja) 2006-07-11 2007-07-09 抗緑内障薬としてのシクロペンタン誘導体

Country Status (10)

Country Link
US (1) US7592366B2 (enExample)
EP (1) EP2043993B1 (enExample)
JP (1) JP5570807B2 (enExample)
AU (1) AU2007272617B2 (enExample)
BR (1) BRPI0714885B8 (enExample)
CA (1) CA2657719C (enExample)
DK (1) DK2043993T3 (enExample)
ES (1) ES2549863T3 (enExample)
PL (1) PL2043993T3 (enExample)
WO (1) WO2008008718A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080015219A1 (en) * 2006-07-11 2008-01-17 Allergan, Inc. Therapeutic compounds
WO2008144623A1 (en) * 2007-05-23 2008-11-27 Allergan, Inc. Cyclic lactams for the treatment of glaucoma or elevated intraocular pressure
KR20100051803A (ko) * 2007-07-03 2010-05-18 알러간, 인코포레이티드 안압을 감소시키기 위한 치료적인 치환된 사이클로펜탄
US7947732B2 (en) * 2007-07-13 2011-05-24 Allergan, Inc. Therapeutic substituted chlorocyclopentanols
US8299068B2 (en) 2010-01-29 2012-10-30 Allergan, Inc. Therapeutically active cyclopentanes
CN104684904B (zh) 2012-08-27 2017-10-13 阿勒根公司 通过使用β‑氯环戊烷的亲水性酯前药减轻中央角膜增厚
US9090595B2 (en) 2012-08-27 2015-07-28 Allergan, Inc. Reduced central corneal thickening by use of hydrophilic ester prodrugs of beta-chlorocyclopentanes
CA2939569A1 (en) * 2014-02-20 2015-11-19 Allergan, Inc. Reduced central corneal thickening by use of hydrophilic ester prodrugs of beta-chlorocyclopentanes
JP6569661B2 (ja) * 2014-02-27 2019-09-04 小野薬品工業株式会社 選択的ep2アゴニスト活性を有する化合物
US9573926B2 (en) 2014-05-22 2017-02-21 Allergan, Inc. Amidoalkylenyl and amidoaryl esters, compositions thereof, and methods for their use
AU2015269064B2 (en) * 2014-06-06 2020-02-13 Allergan, Inc. Novel EP4 agonists as therapeutic compounds
US9540357B1 (en) 2014-07-31 2017-01-10 Allergan, Inc. 15-aryl prostaglandins as EP4 agonists, and methods of use thereof
WO2016054596A1 (en) 2014-10-02 2016-04-07 Allergan, Inc. Ester prodrugs of gamma-lactams and their use
ES2837399T3 (es) 2015-07-23 2021-06-30 Ono Pharmaceutical Co Derivados de ácido 2-(octahidrociclopenta(b)piran-2-il)1,3-tiazol-4-carboxílico y compuestos relacionados como agonistas de EP2 con actividad reductora de la presión intraocular

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980700A (en) * 1971-10-07 1976-09-14 G. D. Searle & Co. Prostaglandin intermediates and optically active isomers thereof
DE2346706A1 (de) * 1973-09-17 1975-04-03 Hoechst Ag Neue, nicht natuerlich vorkommende analoga von prostansaeuren und verfahren zu ihrer herstellung
US4073799A (en) * 1975-02-27 1978-02-14 (Zaidanhojin) Sagami Chemical Research Center Process for producing 3-formylcyclopentanone derivatives
US4094886A (en) * 1976-03-01 1978-06-13 (Zaidanhojin) Sagami Chemical Research Center Process for producing allyl alcohol derivatives useful in prostaglandin synthesis
US5151444B1 (en) * 1987-09-18 1999-07-06 R Tech Ueno Ltd Ocular hypotensive agents
US5352708A (en) * 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5688819A (en) * 1992-09-21 1997-11-18 Allergan Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
JPH07238068A (ja) * 1994-02-24 1995-09-12 Taisho Pharmaceut Co Ltd プロスタグランジンe1類縁体
US6531485B2 (en) * 1997-06-23 2003-03-11 Pfizer Inc. Prostaglandin agonists
JP2001527063A (ja) * 1998-12-24 2001-12-25 小野薬品工業株式会社 ω−シクロアルキル−プロスタグランジンE2誘導体
KR20040023707A (ko) * 2001-07-31 2004-03-18 수캄포 아게 안내압항진 및 녹내장의 치료
US7429669B2 (en) * 2006-06-20 2008-09-30 Allergan, Inc. Therapeutic compounds
JP5532302B2 (ja) * 2006-07-10 2014-06-25 アラーガン インコーポレイテッド 治療化合物
US20080015219A1 (en) * 2006-07-11 2008-01-17 Allergan, Inc. Therapeutic compounds

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