MX2010004487A - Derivados lactamicos sustituidos y sus usos para glaucoma e hipertension ocular. - Google Patents
Derivados lactamicos sustituidos y sus usos para glaucoma e hipertension ocular.Info
- Publication number
- MX2010004487A MX2010004487A MX2010004487A MX2010004487A MX2010004487A MX 2010004487 A MX2010004487 A MX 2010004487A MX 2010004487 A MX2010004487 A MX 2010004487A MX 2010004487 A MX2010004487 A MX 2010004487A MX 2010004487 A MX2010004487 A MX 2010004487A
- Authority
- MX
- Mexico
- Prior art keywords
- substituted lactams
- therapeutic substituted
- therapeutic
- lactams
- disclosed
- Prior art date
Links
- 150000003951 lactams Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- -1 methods Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98191807P | 2007-10-23 | 2007-10-23 | |
| US98483807P | 2007-11-02 | 2007-11-02 | |
| PCT/US2008/080063 WO2009055289A2 (en) | 2007-10-23 | 2008-10-16 | Therapeutic substituted lactams |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010004487A true MX2010004487A (es) | 2010-05-05 |
Family
ID=40521508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010004487A MX2010004487A (es) | 2007-10-23 | 2008-10-16 | Derivados lactamicos sustituidos y sus usos para glaucoma e hipertension ocular. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7998998B2 (enExample) |
| EP (1) | EP2215084B1 (enExample) |
| JP (1) | JP5410438B2 (enExample) |
| KR (1) | KR20100086485A (enExample) |
| CN (1) | CN101868455B (enExample) |
| AU (1) | AU2008317107B2 (enExample) |
| BR (1) | BRPI0820410A2 (enExample) |
| CA (1) | CA2703479C (enExample) |
| IL (1) | IL205278A0 (enExample) |
| MX (1) | MX2010004487A (enExample) |
| NZ (1) | NZ585103A (enExample) |
| WO (1) | WO2009055289A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5524047B2 (ja) * | 2007-05-23 | 2014-06-18 | アラーガン インコーポレイテッド | 緑内障および眼圧上昇の治療用環状ラクタム類 |
| US9440919B2 (en) | 2012-07-19 | 2016-09-13 | Cayman Chemical Company, Inc. | Difluorolactam compositions for EP4-mediated osteo related diseases and conditions |
| US8962863B2 (en) * | 2012-08-21 | 2015-02-24 | Allergan, Inc. | Process for the synthesis of substituted gamma lactams |
| CN103665043B (zh) | 2012-08-30 | 2017-11-10 | 江苏豪森药业集团有限公司 | 一种替诺福韦前药及其在医药上的应用 |
| JP6368351B2 (ja) | 2013-03-15 | 2018-08-01 | ケイマン ケミカル カンパニー， インコーポレーテッド | ジフルオロラクタムアナログを合成する方法 |
| ES2635635T3 (es) | 2013-03-15 | 2017-10-04 | Cayman Chemical Company, Incorporated | Compuestos de difluorolactama como agonistas selectivos del receptor EP4 para su uso en el tratamiento de enfermedades y afecciones mediadas por EP4 |
| WO2014144610A1 (en) | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions |
| EP3021879A2 (en) | 2013-07-19 | 2016-05-25 | Cayman Chemical Company, Incorporated | Methods, systems, and compositions for promoting bone growth |
| US9540357B1 (en) | 2014-07-31 | 2017-01-10 | Allergan, Inc. | 15-aryl prostaglandins as EP4 agonists, and methods of use thereof |
| KR102877633B1 (ko) | 2021-09-01 | 2025-10-28 | 에스케이하이닉스 주식회사 | 반도체 웨이퍼의 불량 분석 방법 및 그 시스템 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4035961A1 (de) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| RU2288913C2 (ru) * | 2001-07-16 | 2006-12-10 | Ф.Хоффманн-Ля Рош Аг | Аналоги простагландинов, способ их получения и фармацевтическая композиция, обладающая селективной агонистической активностью в отношении рецептора ep4 |
| GEP20084341B (en) * | 2003-02-26 | 2008-03-25 | Sugen Inc | Aminoheteroaryl compounds as protein kinase inhibitors |
| WO2005108360A1 (en) * | 2004-05-07 | 2005-11-17 | Janssen Pharmaceutica N.V. | Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| WO2007108360A1 (ja) * | 2006-03-17 | 2007-09-27 | Intellectual Property Bank Corp. | 細径盲管を用いた表面増強ラマン散乱による物質検知方法および物質検知装置、複数物質検知デバイス、盲管 |
| BRPI0807600A2 (pt) * | 2007-02-15 | 2014-07-22 | Allergan Inc | Gama-lactamas para o tratamento de glaucoma ou pressão intraocular elevada |
-
2008
- 2008-10-16 KR KR1020107010956A patent/KR20100086485A/ko not_active Ceased
- 2008-10-16 CN CN2008801167781A patent/CN101868455B/zh not_active Expired - Fee Related
- 2008-10-16 AU AU2008317107A patent/AU2008317107B2/en not_active Ceased
- 2008-10-16 JP JP2010531133A patent/JP5410438B2/ja not_active Expired - Fee Related
- 2008-10-16 EP EP08842624.2A patent/EP2215084B1/en not_active Not-in-force
- 2008-10-16 MX MX2010004487A patent/MX2010004487A/es active IP Right Grant
- 2008-10-16 US US12/739,676 patent/US7998998B2/en active Active
- 2008-10-16 BR BRPI0820410-1A patent/BRPI0820410A2/pt not_active IP Right Cessation
- 2008-10-16 CA CA2703479A patent/CA2703479C/en not_active Expired - Fee Related
- 2008-10-16 NZ NZ585103A patent/NZ585103A/en not_active IP Right Cessation
- 2008-10-16 WO PCT/US2008/080063 patent/WO2009055289A2/en not_active Ceased
-
2010
- 2010-04-22 IL IL205278A patent/IL205278A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7998998B2 (en) | 2011-08-16 |
| CN101868455A (zh) | 2010-10-20 |
| AU2008317107B2 (en) | 2013-09-12 |
| RU2010120015A (ru) | 2011-11-27 |
| EP2215084A2 (en) | 2010-08-11 |
| NZ585103A (en) | 2012-04-27 |
| IL205278A0 (en) | 2010-12-30 |
| CA2703479C (en) | 2017-08-22 |
| CN101868455B (zh) | 2013-11-13 |
| CA2703479A1 (en) | 2009-04-30 |
| US20100292293A1 (en) | 2010-11-18 |
| EP2215084B1 (en) | 2016-09-28 |
| WO2009055289A2 (en) | 2009-04-30 |
| WO2009055289A3 (en) | 2009-06-11 |
| JP2011500818A (ja) | 2011-01-06 |
| KR20100086485A (ko) | 2010-07-30 |
| AU2008317107A1 (en) | 2009-04-30 |
| BRPI0820410A2 (pt) | 2015-05-19 |
| JP5410438B2 (ja) | 2014-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |