MX2009008039A - Gamma lactamas substituidas como agentes terapeuticos. - Google Patents

Gamma lactamas substituidas como agentes terapeuticos.

Info

Publication number
MX2009008039A
MX2009008039A MX2009008039A MX2009008039A MX2009008039A MX 2009008039 A MX2009008039 A MX 2009008039A MX 2009008039 A MX2009008039 A MX 2009008039A MX 2009008039 A MX2009008039 A MX 2009008039A MX 2009008039 A MX2009008039 A MX 2009008039A
Authority
MX
Mexico
Prior art keywords
therapeutic agents
substituted gamma
gamma lactams
lactams
substituted
Prior art date
Application number
MX2009008039A
Other languages
English (en)
Inventor
David W Old
Wha Bin Im
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of MX2009008039A publication Critical patent/MX2009008039A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un compuesto de la fórmula (I) o a una sal, profármaco, o un metabolito del mismo, farmacéuticamente aceptable. Y, A, y B son como se describen aquí. También se describen métodos, composiciones, y medicamentos relacionados con estos compuestos. (ver fórmula (I)).
MX2009008039A 2007-01-31 2008-01-29 Gamma lactamas substituidas como agentes terapeuticos. MX2009008039A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88741507P 2007-01-31 2007-01-31
PCT/US2008/052318 WO2008094912A2 (en) 2007-01-31 2008-01-29 Substituted gamma lactams as therapeutic agents

Publications (1)

Publication Number Publication Date
MX2009008039A true MX2009008039A (es) 2009-08-18

Family

ID=39639429

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009008039A MX2009008039A (es) 2007-01-31 2008-01-29 Gamma lactamas substituidas como agentes terapeuticos.

Country Status (11)

Country Link
US (1) US7960381B2 (es)
EP (1) EP2121672B1 (es)
JP (1) JP5566692B2 (es)
KR (1) KR101561706B1 (es)
CN (1) CN101595106B (es)
AU (1) AU2008210559B2 (es)
BR (1) BRPI0808377B8 (es)
CA (1) CA2676291C (es)
MX (1) MX2009008039A (es)
NZ (1) NZ578698A (es)
WO (1) WO2008094912A2 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8377984B2 (en) * 2008-01-29 2013-02-19 Allergan, Inc. Substituted gamma lactams as therapeutic agents
AU2009239381A1 (en) * 2008-04-24 2009-10-29 Allergan, Inc. Substituted gamma lactams as therapeutic agents
AU2009239369B2 (en) 2008-04-24 2014-03-06 Allergan, Inc. Substituted arylcyclopentenes as prostaglandin EP2 agonists
BRPI0911347A2 (pt) * 2008-04-24 2018-03-20 Allergan Inc gama lactamas substituídas como agentes terapêuticos
JP2011520811A (ja) * 2008-05-09 2011-07-21 アラーガン インコーポレイテッド 治療用の置換チアゾリジノン類、オキサゾリジノン類および関連化合物
AU2009249388B2 (en) * 2008-05-20 2014-04-03 Allergan, Inc. Therapeutic lactams

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1409455B1 (en) * 2001-07-16 2006-01-04 F. Hoffmann-La Roche Ag Prostaglandin analogues-as ep4 receptor agonists
BR0213911A (pt) * 2001-11-05 2004-09-28 Allergan Inc Análogos de Èmega-cicloalquil 17-heteroaril prostaglandina e2 como agonistas do receptor ep2
BR0308166A (pt) * 2002-03-05 2005-01-18 Ono Pharmaceutical Co Compostos de derivados de 8-azaprostaglandina e drogas contendo os compostos como o ingrediente ativo
US6573294B1 (en) * 2002-05-14 2003-06-03 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure
AU2003237520B2 (en) 2002-06-10 2009-01-08 Laboratoires Serono Sa Gamma lactams as prostaglandin agonists and use thereof
US7091231B2 (en) 2004-12-10 2006-08-15 Allergan, Inc. 12-Aryl prostaglandin analogs
EP1856042B1 (en) * 2005-03-10 2012-06-27 Allergan, Inc. Substituted gamma lactams as therapeutic agents
WO2007109578A2 (en) * 2006-03-20 2007-09-27 Allergan, Inc. Substituted gamma lactams as prostaglandin ep2 agonists

Also Published As

Publication number Publication date
EP2121672A2 (en) 2009-11-25
AU2008210559A1 (en) 2008-08-07
KR101561706B1 (ko) 2015-10-19
CA2676291C (en) 2017-11-28
CN101595106A (zh) 2009-12-02
JP2010516817A (ja) 2010-05-20
BRPI0808377A2 (pt) 2014-07-08
CA2676291A1 (en) 2008-08-07
US7960381B2 (en) 2011-06-14
US20100093729A1 (en) 2010-04-15
EP2121672B1 (en) 2014-12-10
JP5566692B2 (ja) 2014-08-06
BRPI0808377B8 (pt) 2021-05-25
CN101595106B (zh) 2014-05-07
KR20090104905A (ko) 2009-10-06
BRPI0808377B1 (pt) 2020-01-21
AU2008210559B2 (en) 2014-03-06
WO2008094912A3 (en) 2008-10-09
NZ578698A (en) 2012-04-27
WO2008094912A2 (en) 2008-08-07
WO2008094912B1 (en) 2008-11-20

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Legal Events

Date Code Title Description
FG Grant or registration