MX2009003081A - Derivados de pirrola utiles para el tratamiento de enfermedades mediadas por citoquinas. - Google Patents

Derivados de pirrola utiles para el tratamiento de enfermedades mediadas por citoquinas.

Info

Publication number
MX2009003081A
MX2009003081A MX2009003081A MX2009003081A MX2009003081A MX 2009003081 A MX2009003081 A MX 2009003081A MX 2009003081 A MX2009003081 A MX 2009003081A MX 2009003081 A MX2009003081 A MX 2009003081A MX 2009003081 A MX2009003081 A MX 2009003081A
Authority
MX
Mexico
Prior art keywords
cytokine
treatment
mediated diseases
derivatives useful
pyrrole derivatives
Prior art date
Application number
MX2009003081A
Other languages
English (en)
Inventor
Richard Heng
Achim Schlapbach
Max Peter Seiler
Guido Koch
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2009003081A publication Critical patent/MX2009003081A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • C07D—HETEROCYCLIC COMPOUNDS
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Abstract

Un compuesto de la Fórmula (I) o una sal farmacéuticamente aceptable o un éster de profármaco del mismo, donde los grupos R1-R6 y A son como se definen en la especificación.
MX2009003081A 2006-09-21 2007-09-19 Derivados de pirrola utiles para el tratamiento de enfermedades mediadas por citoquinas. MX2009003081A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06121036 2006-09-21
PCT/EP2007/008153 WO2008034600A1 (en) 2006-09-21 2007-09-19 Pyrrole derivatives useful for the treatment of cytokine-mediated diseases

Publications (1)

Publication Number Publication Date
MX2009003081A true MX2009003081A (es) 2009-04-01

Family

ID=37684420

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Application Number Title Priority Date Filing Date
MX2009003081A MX2009003081A (es) 2006-09-21 2007-09-19 Derivados de pirrola utiles para el tratamiento de enfermedades mediadas por citoquinas.

Country Status (11)

Country Link
US (1) US20100105664A1 (es)
EP (1) EP2069333A1 (es)
JP (1) JP2010504295A (es)
KR (1) KR20090057032A (es)
CN (1) CN101516874A (es)
AU (1) AU2007299261A1 (es)
BR (1) BRPI0717097A2 (es)
CA (1) CA2662359A1 (es)
MX (1) MX2009003081A (es)
RU (1) RU2009114747A (es)
WO (1) WO2008034600A1 (es)

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WO2011101865A2 (en) 2010-02-19 2011-08-25 Cadila Healthcare Limited Stable pharmaceutical compositions of clopidogrel for parenteral delivery
AU2014248647A1 (en) * 2013-03-12 2015-10-01 Abbvie Inc. Pyrrole amide inhibitors
US9566087B2 (en) 2013-03-15 2017-02-14 Access Scientific, Llc Vascular access device
MX2015016543A (es) 2013-06-27 2017-07-27 Lg Chemical Ltd Derivados de biarilo como agonistas de gpr120.
JP2017505787A (ja) * 2014-02-14 2017-02-23 ザ ユニバーシティ オブ ブリティッシュ コロンビア 治療薬としてのヒトアンドロゲン受容体ｄｎａ結合ドメイン（ｄｂｄ）化合物およびそれらを使用する方法
BR112017013465A2 (pt) * 2014-12-24 2018-03-06 Lg Chem, Ltd derivado de biarila, e, composição farmacêutica.
EP3888731A1 (en) 2015-04-30 2021-10-06 Smiths Medical ASD, Inc. Vascular access device
AU2018326785B2 (en) * 2017-09-03 2023-03-02 Angion Biomedica Corp. Vinylheterocycles as Rho-associated coiled-coil kinase (ROCK) inhibitors
US10569059B2 (en) 2018-03-01 2020-02-25 Asspv, Llc Guidewire retention device
MA54133B1 (fr) 2018-03-08 2022-01-31 Incyte Corp Composés d'aminopyrazine diol utilisés comme inhibiteurs de pi3k-y
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors
BR112022013388A2 (pt) * 2020-01-07 2022-09-20 Disarm Therapeutics Inc Inibidores de sarm1

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WO1997016442A1 (en) 1995-10-31 1997-05-09 Merck & Co., Inc. Substituted pyridyl pyrroles, compositions containing such compounds and methods of use
EP0912548A1 (en) 1996-07-11 1999-05-06 Pfizer Inc. Pyridylpyrrole compounds useful as interleukin- and tnf antagonists
US6372777B1 (en) 1999-12-23 2002-04-16 Icos Corporation Cyclic AMP-specific phosphodiesterase inhibitors
MXPA05006569A (es) * 2002-12-20 2005-09-22 Pharmacia Corp Compuestos que inhiben la proteina cinasa-2 activada por la proteina cinasa activada por el mitogeno.

Also Published As

Publication number Publication date
US20100105664A1 (en) 2010-04-29
EP2069333A1 (en) 2009-06-17
AU2007299261A1 (en) 2008-03-27
CN101516874A (zh) 2009-08-26
BRPI0717097A2 (pt) 2013-11-26
CA2662359A1 (en) 2008-03-27
JP2010504295A (ja) 2010-02-12
RU2009114747A (ru) 2010-10-27
WO2008034600A1 (en) 2008-03-27
KR20090057032A (ko) 2009-06-03

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