JP2010540477A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010540477A5 JP2010540477A5 JP2010526189A JP2010526189A JP2010540477A5 JP 2010540477 A5 JP2010540477 A5 JP 2010540477A5 JP 2010526189 A JP2010526189 A JP 2010526189A JP 2010526189 A JP2010526189 A JP 2010526189A JP 2010540477 A5 JP2010540477 A5 JP 2010540477A5
- Authority
- JP
- Japan
- Prior art keywords
- dimethylamino
- methyl
- ethyl
- independently selected
- fluorine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052757 nitrogen Inorganic materials 0.000 claims 6
- 238000000034 method Methods 0.000 claims 5
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 3
- 229910052731 fluorine Inorganic materials 0.000 claims 3
- 239000011737 fluorine Substances 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 3
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 claims 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 2
- 125000002877 alkyl aryl group Chemical group 0.000 claims 2
- 125000003710 aryl alkyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 2
- 229910052794 bromium Inorganic materials 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 239000000460 chlorine Substances 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- YTLYLLTVENPWFT-UPHRSURJSA-N (Z)-3-aminoacrylic acid Chemical class N\C=C/C(O)=O YTLYLLTVENPWFT-UPHRSURJSA-N 0.000 claims 1
- CRNHLPZBBWBNDN-UHFFFAOYSA-N 2-(dimethylamino)prop-2-enenitrile Chemical compound CN(C)C(=C)C#N CRNHLPZBBWBNDN-UHFFFAOYSA-N 0.000 claims 1
- 229910005965 SO 2 Inorganic materials 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- MVUMJYQUKKUOHO-AATRIKPKSA-N ethyl (e)-3-(dimethylamino)prop-2-enoate Chemical compound CCOC(=O)\C=C\N(C)C MVUMJYQUKKUOHO-AATRIKPKSA-N 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 229910052740 iodine Inorganic materials 0.000 claims 1
- 239000011630 iodine Substances 0.000 claims 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims 1
- MVPDNJQLPITPIX-SNAWJCMRSA-N methyl (e)-3-(dimethylamino)prop-2-enoate Chemical compound COC(=O)\C=C\N(C)C MVPDNJQLPITPIX-SNAWJCMRSA-N 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 claims 1
- 125000003386 piperidinyl group Chemical group 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07117232.4 | 2007-09-26 | ||
| EP07117232A EP2042482A1 (de) | 2007-09-26 | 2007-09-26 | Verfahren zur Herstellung von 2-Dihalogenacyl-3-amino-acrylsäure-Derivaten |
| PCT/EP2008/007612 WO2009043444A1 (de) | 2007-09-26 | 2008-09-13 | Verfahren zur herstellung von 2-dihalogenacyl-3-amino-acrylsäure-derivaten |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010540477A JP2010540477A (ja) | 2010-12-24 |
| JP2010540477A5 true JP2010540477A5 (enExample) | 2011-11-04 |
| JP5292405B2 JP5292405B2 (ja) | 2013-09-18 |
Family
ID=39112838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010526189A Active JP5292405B2 (ja) | 2007-09-26 | 2008-09-13 | ２−ジハロアシル−３−アミノアクリル酸誘導体の調製方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8258335B2 (enExample) |
| EP (2) | EP2042482A1 (enExample) |
| JP (1) | JP5292405B2 (enExample) |
| CN (1) | CN101808979B (enExample) |
| BR (1) | BRPI0817747A8 (enExample) |
| DK (1) | DK2195284T3 (enExample) |
| ES (1) | ES2627700T3 (enExample) |
| TW (1) | TWI419863B (enExample) |
| WO (1) | WO2009043444A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5602131B2 (ja) * | 2008-05-02 | 2014-10-08 | ビーエーエスエフ ソシエタス・ヨーロピア | ハロゲン置換２−（アミノメチリデン）−３−オキソ酪酸エステルの製造方法 |
| WO2009133178A1 (de) | 2008-05-02 | 2009-11-05 | Basf Se | Verfahren zur herstellung von 2-(aminomethyliden)-4,4-difluor-3-oxobuttersäureestern |
| AU2009243550B2 (en) | 2008-05-05 | 2014-06-26 | Basf Se | Method for preparing 1,3,4-substituted pyrazol compounds |
| EP2307384B1 (en) | 2008-07-21 | 2012-04-25 | Basf Se | Process for preparing 1,3-disubstituted pyrazolecarboxylic esters |
| JP5228817B2 (ja) * | 2008-11-12 | 2013-07-03 | セントラル硝子株式会社 | ピラゾール化合物の製造方法 |
| US8871947B2 (en) | 2013-02-04 | 2014-10-28 | KingChem LLC | Preparation of alkyl 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid ester |
| WO2015085464A1 (en) | 2013-12-09 | 2015-06-18 | King Chem, Llc | Process for preparing alkyl 3-difluoromethyl-1-methyl-1h-pyrazole-4-carboxylate and its analogs |
| CN105541716B (zh) | 2015-03-26 | 2024-02-23 | Ａｇｃ株式会社 | 吡唑衍生物的制造方法 |
| CN106554311B (zh) * | 2015-09-28 | 2019-03-01 | 常州市卜弋科研化工有限公司 | 3-氟代烷基-1-甲基吡唑-4-羧酸的制备方法 |
| WO2017054112A1 (zh) | 2015-09-28 | 2017-04-06 | 常州市卜弋科研化工有限公司 | 3-氟代烷基-1-甲基吡唑-4-羧酸的制备方法 |
| CN109216764B (zh) * | 2017-07-05 | 2020-09-15 | 宁德时代新能源科技股份有限公司 | 一种电解液及电化学装置 |
| CN110577503A (zh) | 2019-08-02 | 2019-12-17 | 宿迁市科莱博生物化学有限公司 | 一种卤素取代化合物及其制备方法和应用 |
| CN117603070A (zh) * | 2023-11-10 | 2024-02-27 | 安徽泓泽新材料科技有限公司 | 一种2-二氟乙酰基-3-二甲胺基丙烯酸乙酯化合物及其制备方法和应用 |
| CN117603069A (zh) * | 2023-11-10 | 2024-02-27 | 安徽泓泽新材料科技有限公司 | 一种2-二氟乙酰基-3-二甲胺基丙烯酸乙酯化合物及其制备方法和应用 |
| CN117603072A (zh) * | 2023-11-10 | 2024-02-27 | 安徽泓泽新材料科技有限公司 | 一种2-二氟乙酰基-3-二甲胺基丙烯酸化合物及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3632243B2 (ja) * | 1994-07-28 | 2005-03-23 | 旭硝子株式会社 | ジフルオロ酢酸フルオリドおよびジフルオロ酢酸エステルの製造方法 |
| US5498624A (en) | 1995-05-03 | 1996-03-12 | Monsanto Company | Selected pyrazolyl derivatives |
| KR20000035081A (ko) | 1998-11-10 | 2000-06-26 | 마크 에스. 아들러 | 2-(트리할로아세틸)-3-(치환된 아미노)-2-프로페노에이트 제조방법 |
| DE10161978A1 (de) * | 2001-12-17 | 2003-06-26 | Bayer Ag | Verfahren zur Herstellung von 2-Halogenacyl-3-amino-acrylsäure-derivate |
| DE10215292A1 (de) | 2002-02-19 | 2003-08-28 | Bayer Cropscience Ag | Disubstitutierte Pyrazolylcarbocanilide |
| DE10349500A1 (de) | 2003-10-23 | 2005-06-02 | Bayer Cropscience Ag | Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern |
| CN101627008A (zh) * | 2006-12-28 | 2010-01-13 | 三井化学Agro株式会社 | 2-含氟酰基-3-氨基丙烯腈衍生物及其制备方法 |
| PL2128139T3 (pl) * | 2007-02-20 | 2014-01-31 | Mitsui Chemicals Agro Inc | Zawierająca fluor pochodna pirazolokarbonitrylowa i sposób jej otrzymywania, oraz zawierająca fluor pochodna kwasu pirazolokarboksylowego, otrzymana przy użyciu zawierającej fluor pochodnej pirazolokarbonitrylowej i sposób jej otrzymywania |
| EP2072497A1 (de) * | 2007-12-21 | 2009-06-24 | Bayer CropScience AG | Verfahren zum Herstellen von 2-Fluoracyl-3-amino-acrylsäure-Derivaten |
| JP5602131B2 (ja) * | 2008-05-02 | 2014-10-08 | ビーエーエスエフ ソシエタス・ヨーロピア | ハロゲン置換２−（アミノメチリデン）−３−オキソ酪酸エステルの製造方法 |
-
2007
- 2007-09-26 EP EP07117232A patent/EP2042482A1/de not_active Ceased
-
2008
- 2008-09-13 DK DK08802162.1T patent/DK2195284T3/en active
- 2008-09-13 WO PCT/EP2008/007612 patent/WO2009043444A1/de not_active Ceased
- 2008-09-13 ES ES08802162.1T patent/ES2627700T3/es active Active
- 2008-09-13 EP EP08802162.1A patent/EP2195284B1/de active Active
- 2008-09-13 CN CN2008801086924A patent/CN101808979B/zh active Active
- 2008-09-13 JP JP2010526189A patent/JP5292405B2/ja active Active
- 2008-09-13 US US12/679,709 patent/US8258335B2/en not_active Expired - Fee Related
- 2008-09-13 BR BRPI0817747A patent/BRPI0817747A8/pt active IP Right Grant
- 2008-09-25 TW TW097136780A patent/TWI419863B/zh not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010540477A5 (enExample) | ||
| JP2022043078A5 (enExample) | ||
| RU2488582C2 (ru) | Бициклозамещенные азопроизводные пиразолона, способ их получения и фармацевтическое применение | |
| JP2011037841A5 (enExample) | ||
| JP2013512277A5 (enExample) | ||
| JP2008523069A5 (enExample) | ||
| JP2012149045A5 (ja) | ベンゾ［ｂ］ナフト［１，２−ｄ］フラン化合物 | |
| JP2010500343A5 (enExample) | ||
| JP2013505929A5 (enExample) | ||
| RU2009110413A (ru) | Способ получения производных 3-дигалогенметил-пиразол-4-карбоновой кислоты | |
| MX2010007977A (es) | Derivados de carboxamidas azabiciclicas, su preparacion y su aplicacion en terapeutica. | |
| JP2013543842A5 (enExample) | ||
| JP2013546173A5 (enExample) | ||
| DE502004012095D1 (de) | Verfahren zum herstellen von 2-dihalogenacyl-3-amino-acryls ureestern und 3-dihalogenmethyl-pyrazol-4-carbons ureestern | |
| MY150289A (en) | Derivatives of indole-2-carboxamides and of azaindole-2-carboxamides substituted with a silanyl group, preparation thereof and therapeutic use thereof | |
| JP2009526034A5 (enExample) | ||
| JP2010529994A5 (enExample) | ||
| PE20091403A1 (es) | Derivados de carboxamidas n-azabiciclicas y su preparacion | |
| JP2010505873A5 (ja) | 化合物、会合複合体、及び会合複合体を形成する方法 | |
| JP2012515142A5 (enExample) | ||
| JP2015501820A5 (enExample) | ||
| RS53710B2 (sr) | Jedinjenja kao antagonisti b1 bradikinina | |
| JP2011523952A5 (enExample) | ||
| JP2010079247A5 (enExample) | ||
| JP2014520901A5 (enExample) |