JP2007513170A5 - - Google Patents
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- Publication number
- JP2007513170A5 JP2007513170A5 JP2006542750A JP2006542750A JP2007513170A5 JP 2007513170 A5 JP2007513170 A5 JP 2007513170A5 JP 2006542750 A JP2006542750 A JP 2006542750A JP 2006542750 A JP2006542750 A JP 2006542750A JP 2007513170 A5 JP2007513170 A5 JP 2007513170A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- heterocyclyl
- alkylenyl
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 125000000217 alkyl group Chemical group 0.000 claims 100
- 125000005466 alkylenyl group Chemical group 0.000 claims 60
- 125000000623 heterocyclic group Chemical group 0.000 claims 60
- 125000001072 heteroaryl group Chemical group 0.000 claims 51
- 125000003118 aryl group Chemical group 0.000 claims 40
- 125000000304 alkynyl group Chemical group 0.000 claims 36
- 125000003342 alkenyl group Chemical group 0.000 claims 33
- 125000002947 alkylene group Chemical group 0.000 claims 31
- 125000003545 alkoxy group Chemical group 0.000 claims 25
- 125000004450 alkenylene group Chemical group 0.000 claims 24
- 125000004419 alkynylene group Chemical group 0.000 claims 24
- 150000001875 compounds Chemical class 0.000 claims 20
- 229910052739 hydrogen Inorganic materials 0.000 claims 20
- 239000001257 hydrogen Substances 0.000 claims 20
- 150000003839 salts Chemical class 0.000 claims 19
- 125000004104 aryloxy group Chemical group 0.000 claims 18
- 125000005553 heteroaryloxy group Chemical group 0.000 claims 18
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 18
- 229910052736 halogen Inorganic materials 0.000 claims 15
- 150000002367 halogens Chemical class 0.000 claims 15
- 150000002431 hydrogen Chemical class 0.000 claims 14
- -1 nitro, hydroxy Chemical group 0.000 claims 13
- 125000001424 substituent group Chemical group 0.000 claims 13
- 125000006374 C2-C10 alkenyl group Chemical group 0.000 claims 12
- 125000003282 alkyl amino group Chemical group 0.000 claims 12
- 125000000732 arylene group Chemical group 0.000 claims 12
- 229910052799 carbon Inorganic materials 0.000 claims 12
- 125000004432 carbon atom Chemical group C* 0.000 claims 12
- 125000004093 cyano group Chemical group *C#N 0.000 claims 12
- 125000004663 dialkyl amino group Chemical group 0.000 claims 12
- 125000005549 heteroarylene group Chemical group 0.000 claims 12
- 125000001188 haloalkyl group Chemical group 0.000 claims 9
- 125000005842 heteroatom Chemical group 0.000 claims 9
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- 125000002877 alkyl aryl group Chemical group 0.000 claims 6
- 125000005529 alkyleneoxy group Chemical group 0.000 claims 6
- 125000005532 aryl alkyleneoxy group Chemical group 0.000 claims 6
- ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 claims 6
- 125000004438 haloalkoxy group Chemical group 0.000 claims 6
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 6
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 6
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 claims 6
- 125000001153 fluoro group Chemical group F* 0.000 claims 4
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 4
- 125000004414 alkyl thio group Chemical group 0.000 claims 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims 1
- 125000004200 2-methoxyethyl group Chemical group [H]C([H])([H])OC([H])([H])C([H])([H])* 0.000 claims 1
- 125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 claims 1
- 125000001313 C5-C10 heteroaryl group Chemical group 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000005745 ethoxymethyl group Chemical group [H]C([H])([H])C([H])([H])OC([H])([H])* 0.000 claims 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 0 CC1(*)C=Nc2c3[n](*)c(*)nc3c(N)nc2C=C1 Chemical compound CC1(*)C=Nc2c3[n](*)c(*)nc3c(N)nc2C=C1 0.000 description 2
- SMBYUOXUISCLCF-UHFFFAOYSA-N CCCN(C)CC Chemical compound CCCN(C)CC SMBYUOXUISCLCF-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52677203P | 2003-12-04 | 2003-12-04 | |
| PCT/US2004/040383 WO2005076783A2 (en) | 2003-12-04 | 2004-12-03 | Sulfone substituted imidazo ring ethers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007513170A JP2007513170A (ja) | 2007-05-24 |
| JP2007513170A5 true JP2007513170A5 (enExample) | 2008-01-31 |
Family
ID=34860172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006542750A Pending JP2007513170A (ja) | 2003-12-04 | 2004-12-03 | スルホン置換イミダゾ環エーテル |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7939526B2 (enExample) |
| EP (1) | EP1694674A4 (enExample) |
| JP (1) | JP2007513170A (enExample) |
| CN (1) | CN1914203A (enExample) |
| AR (1) | AR048289A1 (enExample) |
| AU (1) | AU2004315771A1 (enExample) |
| CA (1) | CA2549216A1 (enExample) |
| TW (1) | TW200533352A (enExample) |
| WO (1) | WO2005076783A2 (enExample) |
Families Citing this family (68)
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| WO2003103584A2 (en) | 2002-06-07 | 2003-12-18 | 3M Innovative Properties Company | Ether substituted imidazopyridines |
| US20040265351A1 (en) | 2003-04-10 | 2004-12-30 | Miller Richard L. | Methods and compositions for enhancing immune response |
| JP2007501252A (ja) | 2003-08-05 | 2007-01-25 | スリーエム イノベイティブ プロパティズ カンパニー | 免疫応答調整剤を含有する製剤 |
| AR045261A1 (es) | 2003-08-12 | 2005-10-19 | 3M Innovative Properties Co | Compuestos que contienen imidazo quinolina o imidazo piridina sustituidos; composiciones farmaceuticas que los contienen y su uso en la preparacion de medicamentos inmunomoduladores |
| ES2406730T3 (es) | 2003-08-27 | 2013-06-07 | 3M Innovative Properties Company | Imidazoquinolinas sustituidas con ariloxi y arilalquilenoxi |
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| AR046046A1 (es) | 2003-10-03 | 2005-11-23 | 3M Innovative Properties Co | Imidazoquinolinas alcoxi sustituidas. composiciones farmaceuticas. |
| US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
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| ES2392648T3 (es) | 2004-12-30 | 2012-12-12 | 3M Innovative Properties Company | Compuestos quirales sustituidos que contienen un núcleo 1,2-imidazo-4,5-c condensado |
| PT1830876E (pt) | 2004-12-30 | 2015-07-13 | Meda Ab | Utilização de imiquimod para o tratamento de metástases cutâneas derivadas de um tumor cancerígeno da mama |
| JP5543068B2 (ja) | 2004-12-30 | 2014-07-09 | スリーエム イノベイティブ プロパティズ カンパニー | キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物 |
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| WO2007120121A2 (en) | 2005-02-09 | 2007-10-25 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted thiazolo[4,5-c] ring compounds and methods |
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2004
- 2004-12-03 JP JP2006542750A patent/JP2007513170A/ja active Pending
- 2004-12-03 TW TW093137541A patent/TW200533352A/zh unknown
- 2004-12-03 AU AU2004315771A patent/AU2004315771A1/en not_active Abandoned
- 2004-12-03 CA CA002549216A patent/CA2549216A1/en not_active Abandoned
- 2004-12-03 AR ARP040104518A patent/AR048289A1/es unknown
- 2004-12-03 WO PCT/US2004/040383 patent/WO2005076783A2/en not_active Ceased
- 2004-12-03 US US10/596,117 patent/US7939526B2/en not_active Expired - Fee Related
- 2004-12-03 EP EP04821353A patent/EP1694674A4/en not_active Withdrawn
- 2004-12-03 CN CNA2004800414001A patent/CN1914203A/zh active Pending