|
WO2010021720A1
(en)
|
2008-08-19 |
2010-02-25 |
Nektar Therapeutics |
Conjugates of small-interfering nucleic acids
|
|
TWI510246B
(zh)
|
2010-04-30 |
2015-12-01 |
Molecular Partners Ag |
抑制vegf-a受體交互作用的經修飾結合性蛋白質
|
|
CA2818969C
(en)
|
2010-11-26 |
2020-04-14 |
Molecular Partners Ag |
Improved n-terminal capping modules for designed ankyrin repeat proteins
|
|
WO2012112687A1
(en)
|
2011-02-15 |
2012-08-23 |
Immunogen, Inc. |
Methods of preparation of conjugates
|
|
AU2012272930B2
(en)
|
2011-06-21 |
2015-06-11 |
Immunogen, Inc. |
Novel maytansinoid derivatives with peptide linker and conjugates thereof
|
|
HK1211208A1
(zh)
|
2012-08-22 |
2016-05-20 |
Immunogen, Inc. |
細胞毒性苯並二氮呯衍生物
|
|
EP2738180A1
(en)
|
2012-11-30 |
2014-06-04 |
Molecular Partners AG |
Binding proteins comprising at least two binding domains against HER2.
|
|
JP6423804B2
(ja)
|
2013-02-28 |
2018-11-14 |
イミュノジェン・インコーポレーテッド |
細胞結合剤及び細胞毒性剤を含む複合体
|
|
EP3566750A3
(en)
|
2013-02-28 |
2020-04-08 |
ImmunoGen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
CN105209483B
(zh)
|
2013-05-31 |
2021-07-27 |
分子组合公司 |
与肝细胞生长因子结合的设计锚蛋白重复蛋白
|
|
WO2014194030A2
(en)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
CA2929087A1
(en)
|
2013-10-31 |
2015-05-07 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
HRP20201906T1
(hr)
|
2013-12-20 |
2021-04-02 |
Fred Hutchinson Cancer Research Center |
Označene kimerne efektorske molekule i njihovi receptori
|
|
US10665324B2
(en)
|
2014-07-07 |
2020-05-26 |
Yeda Research And Development Co. Ltd. |
Method of computational protein design
|
|
EP3778601A1
(en)
|
2014-09-03 |
2021-02-17 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
WO2016036804A1
(en)
|
2014-09-03 |
2016-03-10 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
EP4406604A3
(en)
|
2015-03-05 |
2024-10-23 |
Fred Hutchinson Cancer Center |
Immunomodulatory fusion proteins and uses thereof
|
|
EP3277711B9
(en)
|
2015-04-02 |
2023-08-16 |
Molecular Partners AG |
Designed ankyrin repeat domains with binding specificity for serum albumin
|
|
US20180355318A1
(en)
|
2015-04-29 |
2018-12-13 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
EP3288570A4
(en)
|
2015-04-29 |
2018-11-21 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
|
US20190012428A1
(en)
*
|
2015-12-16 |
2019-01-10 |
University Of Washington |
Repeat protein architectures
|
|
KR20240144489A
(ko)
|
2016-04-14 |
2024-10-02 |
프레드 허친슨 캔서 센터 |
표적화 핵산 나노수송체를 이용하여 치료 세포를 프로그램화하기 위한 조성물 및 방법
|
|
AU2017331329B2
(en)
|
2016-09-22 |
2020-10-29 |
Molecular Partners Ag |
Recombinant binding proteins and their use
|
|
CA3052779A1
(en)
|
2017-02-17 |
2018-08-23 |
Fred Hutchinson Cancer Research Center |
Combination therapies for treatment of bcma-related cancers and autoimmune disorders
|
|
CN110366431B
(zh)
|
2017-02-28 |
2023-07-18 |
伊缪诺金公司 |
具有自分解肽接头的类美登素衍生物和其缀合物
|
|
WO2018165046A1
(en)
|
2017-03-07 |
2018-09-13 |
Igc Bio, Inc. |
A computational pipeline for antibody modeling and design
|
|
CN119409836A
(zh)
|
2017-03-17 |
2025-02-11 |
弗雷德哈钦森癌症中心 |
免疫调节融合蛋白及其用途
|
|
TW201839001A
(zh)
|
2017-04-20 |
2018-11-01 |
美商伊繆諾金公司 |
細胞毒性苯并二氮平衍生物及其綴合物
|
|
JP2021508714A
(ja)
|
2017-12-28 |
2021-03-11 |
イミュノジェン・インコーポレーテッド |
ベンゾジアゼピン誘導体
|
|
EP3849565A4
(en)
|
2018-09-12 |
2022-12-28 |
Fred Hutchinson Cancer Research Center |
REDUCTION OF CD33 EXPRESSION TO SELECTIVELY PROTECT THERAPEUTIC CELLS
|
|
JP2022527449A
(ja)
|
2019-03-21 |
2022-06-02 |
イミュノジェン・インコーポレーテッド |
細胞結合剤-薬物複合体の調製方法
|
|
EP3947395A1
(en)
|
2019-03-29 |
2022-02-09 |
ImmunoGen, Inc. |
Cytotoxic bis-benzodiazepine derivatives and conjugates thereof with cell-binding agents for inhibiting abnormal cell growth or for treating proliferative diseases
|
|
EP4316524A3
(en)
|
2019-04-26 |
2024-04-24 |
ImmunoGen, Inc. |
Camptothecin derivatives
|
|
CA3139164A1
(en)
|
2019-06-04 |
2020-12-10 |
Molecular Partners Ag |
Recombinant fap binding proteins and their use
|
|
AU2020286715A1
(en)
|
2019-06-04 |
2021-12-23 |
Molecular Partners Ag |
Recombinant 4-1 BB binding proteins and their use
|
|
WO2020245171A1
(en)
|
2019-06-04 |
2020-12-10 |
Molecular Partners Ag |
Designed ankyrin repeat domain with improved stability
|
|
EP3994270A1
(en)
|
2019-07-02 |
2022-05-11 |
Fred Hutchinson Cancer Research Center |
Recombinant ad35 vectors and related gene therapy improvements
|
|
WO2021116470A2
(en)
|
2019-12-11 |
2021-06-17 |
Molecular Partners Ag |
Recombinant peptide-mhc complex binding proteins and their generation and use
|
|
CA3161321A1
(en)
|
2019-12-11 |
2021-06-17 |
Victor LEVITSKY |
Recombinant peptide-mhc complex binding proteins and their generation and use
|
|
US20230142283A1
(en)
*
|
2020-03-05 |
2023-05-11 |
University Of Washington |
Rigid helical junctions for modular repeat protein sculpting and methods of use
|
|
WO2021224686A1
(en)
|
2020-05-06 |
2021-11-11 |
Molecular Partners Ag |
Novel ankyrin repeat binding proteins and their uses
|
|
CA3178785A1
(en)
|
2020-05-14 |
2021-11-18 |
Nicolo RIGAMONTI |
Multispecific proteins
|
|
JP2023528207A
(ja)
|
2020-05-14 |
2023-07-04 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
組換えcd40結合タンパク質及びそれらの使用
|
|
EP4263608A1
(en)
|
2020-12-16 |
2023-10-25 |
Molecular Partners AG |
Recombinant cd3 binding proteins and their use
|
|
CA3202358A1
(en)
|
2020-12-16 |
2022-06-23 |
Andreas BOSSHART |
Novel slow-release prodrugs
|
|
AU2022233791A1
(en)
|
2021-03-09 |
2023-09-28 |
Molecular Partners Ag |
Novel darpin based cd123 engagers
|
|
JP2024509890A
(ja)
|
2021-03-09 |
2024-03-05 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
プロテアーゼ切断可能なプロドラッグ
|
|
WO2022190010A1
(en)
|
2021-03-09 |
2022-09-15 |
Molecular Partners Ag |
Novel darpin based cd33 engagers
|
|
WO2022190016A1
(en)
|
2021-03-09 |
2022-09-15 |
Molecular Partners Ag |
Novel darpin based multi-specific t-cell engagers
|
|
KR20240122764A
(ko)
|
2021-12-14 |
2024-08-13 |
몰리큘라 파트너스 아게 |
이중 결합 특이성을 갖는 설계된 반복 도메인과 이의 용도
|
|
WO2023131707A1
(en)
*
|
2022-01-07 |
2023-07-13 |
Universität Zürich |
Stabilizing n-cap sequences for armadillo repeat proteins
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
CN119731200A
(zh)
|
2022-08-01 |
2025-03-28 |
分子合作伙伴股份公司 |
经电荷修饰设计的重复结构域及其用途
|
|
WO2024179981A1
(en)
|
2023-02-27 |
2024-09-06 |
Molecular Partners Ag |
Darpins for use in reducing renal accumulation of drugs
|
|
AU2024286934A1
(en)
|
2023-06-06 |
2025-12-18 |
Molecular Partners Ag |
Recombinant cd2 binding proteins and their use
|
|
WO2024251628A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd16a binding proteins and their use
|
|
WO2024251695A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd47 binding proteins and their use
|
|
WO2025068607A1
(en)
*
|
2023-09-29 |
2025-04-03 |
Universität Zürich |
Modular armadillo repeat proteins
|
|
WO2025101820A1
(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2025146487A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Multispecific binding proteins
|
|
WO2025146491A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity for cd117 and cd47-binding agent
|
|
WO2025146490A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Recombinant cd117 binding proteins and their use
|
|
WO2025163144A1
(en)
|
2024-01-31 |
2025-08-07 |
Molecular Partners Ag |
Recombinant mesothelin binding proteins and their use
|
|
WO2025163082A1
(en)
|
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2025-08-07 |
Molecular Partners Ag |
Dll3-specific binding constructs and their use in radiotherapy
|
|
WO2025181039A1
(en)
|
2024-03-01 |
2025-09-04 |
Molecular Partners Ag |
Therapeutic combinations comprising a multi-specific t cell engager
|
|
WO2025245169A1
(en)
|
2024-05-21 |
2025-11-27 |
Fred Hutchinson Cancer Center |
Immunotherapy cells equipped with a collagen-targeting payload
|