|
EP2323695B1
(en)
|
2008-08-19 |
2018-12-05 |
Nektar Therapeutics |
Complexes of small-interfering nucleic acids
|
|
TWI510246B
(zh)
|
2010-04-30 |
2015-12-01 |
Molecular Partners Ag |
抑制vegf-a受體交互作用的經修飾結合性蛋白質
|
|
EP2643349B1
(en)
|
2010-11-26 |
2019-09-04 |
Molecular Partners AG |
Designed repeat proteins binding to serum albumin
|
|
KR20190089048A
(ko)
|
2011-02-15 |
2019-07-29 |
이뮤노젠 아이엔씨 |
컨쥬게이트의 제조방법
|
|
SG10201605041VA
(en)
|
2011-06-21 |
2016-08-30 |
Immunogen Inc |
Novel maytansinoid derivatives with peptide linker and conjugates thereof
|
|
EP2887965A1
(en)
|
2012-08-22 |
2015-07-01 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
EP2738180A1
(en)
|
2012-11-30 |
2014-06-04 |
Molecular Partners AG |
Binding proteins comprising at least two binding domains against HER2.
|
|
US9901647B2
(en)
|
2013-02-28 |
2018-02-27 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
WO2014134483A2
(en)
|
2013-02-28 |
2014-09-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
WO2014194030A2
(en)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
US11453708B2
(en)
|
2013-05-31 |
2022-09-27 |
Molecular Partners Ag |
Designed ankyrin repeat proteins binding to hepatocyte growth factor
|
|
NZ758715A
(en)
|
2013-10-31 |
2023-01-27 |
Seattle Children’S Hospital Dba Seattle Children’S Res Institute |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
SG11201605046YA
(en)
|
2013-12-20 |
2016-07-28 |
Hutchinson Fred Cancer Res |
Tagged chimeric effector molecules and receptors thereof
|
|
US10665324B2
(en)
|
2014-07-07 |
2020-05-26 |
Yeda Research And Development Co. Ltd. |
Method of computational protein design
|
|
US9381256B2
(en)
|
2014-09-03 |
2016-07-05 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
US9669102B2
(en)
|
2014-09-03 |
2017-06-06 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
ES2979088T3
(es)
|
2015-03-05 |
2024-09-24 |
Fred Hutchinson Cancer Center |
Proteínas de fusión inmunomoduladoras y usos de las mismas
|
|
US9458211B1
(en)
|
2015-04-02 |
2016-10-04 |
Molecular Partners Ag |
Recombinant proteins that simultaneously bind HGF, VEGF-A and serum albumin, comprising ankyrin repeat domains
|
|
US20180355318A1
(en)
|
2015-04-29 |
2018-12-13 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
WO2016176652A2
(en)
|
2015-04-29 |
2016-11-03 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
|
WO2017106728A2
(en)
*
|
2015-12-16 |
2017-06-22 |
University Of Washington |
Repeat protein architectures
|
|
EP4711465A2
(en)
|
2016-04-14 |
2026-03-18 |
Fred Hutchinson Cancer Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
AR109680A1
(es)
|
2016-09-22 |
2019-01-09 |
Molecular Partners Ag |
Proteínas recombinantes y sus usos
|
|
CN110461335A
(zh)
|
2017-02-17 |
2019-11-15 |
弗雷德哈钦森癌症研究中心 |
用于治疗bcma相关癌症和自身免疫性失调的联合疗法
|
|
RU2022101392A
(ru)
|
2017-02-28 |
2022-03-02 |
Иммуноджен, Инк. |
Производные майтанзиноида с саморасщепляющимися пептидными линкерами и их конъюгаты
|
|
WO2018165046A1
(en)
|
2017-03-07 |
2018-09-13 |
Igc Bio, Inc. |
A computational pipeline for antibody modeling and design
|
|
US11725210B2
(en)
|
2017-03-17 |
2023-08-15 |
Fred Hutchinson Cancer Center |
Immunomodulatory fusion proteins and uses thereof
|
|
WO2018195243A1
(en)
|
2017-04-20 |
2018-10-25 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives and conjugates thereof
|
|
TW202413360A
(zh)
|
2017-12-28 |
2024-04-01 |
美商伊繆諾金公司 |
苯二氮平衍生物
|
|
EP3849565A4
(en)
|
2018-09-12 |
2022-12-28 |
Fred Hutchinson Cancer Research Center |
REDUCTION OF CD33 EXPRESSION TO SELECTIVELY PROTECT THERAPEUTIC CELLS
|
|
TW202102270A
(zh)
|
2019-03-21 |
2021-01-16 |
美商伊繆諾金公司 |
製備細胞結合劑-藥物結合物之方法
|
|
CN113661172A
(zh)
|
2019-03-29 |
2021-11-16 |
伊缪诺金公司 |
用于抑制异常细胞生长或治疗增生性疾病的细胞毒性双苯并二氮杂䓬衍生物及其与细胞结合剂的缀合物
|
|
EP3958977B1
(en)
|
2019-04-26 |
2023-09-13 |
ImmunoGen, Inc. |
Camptothecin derivatives
|
|
AU2020286600A1
(en)
|
2019-06-04 |
2021-12-23 |
Molecular Partners Ag |
Recombinant FAP binding proteins and their use
|
|
EP3980452A1
(en)
|
2019-06-04 |
2022-04-13 |
Molecular Partners AG |
Recombinant 4-1bb binding proteins and their use
|
|
CA3138805A1
(en)
|
2019-06-04 |
2020-12-10 |
Johannes Schilling |
Designed ankyrin repeat domain with improved stability
|
|
SG11202111943UA
(en)
|
2019-07-02 |
2021-11-29 |
Hutchinson Fred Cancer Res |
Recombinant ad35 vectors and related gene therapy improvements
|
|
CN114929730A
(zh)
|
2019-12-11 |
2022-08-19 |
分子合作伙伴股份公司 |
重组肽-mhc复合物结合蛋白及其生成和用途
|
|
WO2021116470A2
(en)
|
2019-12-11 |
2021-06-17 |
Molecular Partners Ag |
Recombinant peptide-mhc complex binding proteins and their generation and use
|
|
US20230142283A1
(en)
*
|
2020-03-05 |
2023-05-11 |
University Of Washington |
Rigid helical junctions for modular repeat protein sculpting and methods of use
|
|
MX2022013945A
(es)
|
2020-05-06 |
2023-02-14 |
Molecular Partners Ag |
Nuevas proteinas de union a repeticiones de anquirina y sus usos.
|
|
JP2023528204A
(ja)
|
2020-05-14 |
2023-07-04 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
多選択性タンパク質
|
|
US20240279309A1
(en)
|
2020-05-14 |
2024-08-22 |
Molecular Partners Ag |
Recombinant cd40 binding proteins and their use
|
|
WO2022130300A1
(en)
|
2020-12-16 |
2022-06-23 |
Molecular Partners Ag |
Novel slow-release prodrugs
|
|
KR20230120139A
(ko)
|
2020-12-16 |
2023-08-16 |
몰리큘라 파트너스 아게 |
재조합 cd3 결합 단백질 및 이의 용도
|
|
EP4304730A1
(en)
|
2021-03-09 |
2024-01-17 |
Molecular Partners AG |
Novel darpin based cd33 engagers
|
|
AU2022233791A1
(en)
|
2021-03-09 |
2023-09-28 |
Molecular Partners Ag |
Novel darpin based cd123 engagers
|
|
JP2024509904A
(ja)
|
2021-03-09 |
2024-03-05 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
新規なDARPinに基づく多重特異性T細胞エンゲージャ
|
|
US20240156980A1
(en)
|
2021-03-09 |
2024-05-16 |
Molecular Partners Ag |
Protease cleavable prodrugs
|
|
IL313411A
(en)
|
2021-12-14 |
2024-08-01 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity and their use
|
|
WO2023131707A1
(en)
*
|
2022-01-07 |
2023-07-13 |
Universität Zürich |
Stabilizing n-cap sequences for armadillo repeat proteins
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
CN119731200A
(zh)
|
2022-08-01 |
2025-03-28 |
分子合作伙伴股份公司 |
经电荷修饰设计的重复结构域及其用途
|
|
WO2024179981A1
(en)
|
2023-02-27 |
2024-09-06 |
Molecular Partners Ag |
Darpins for use in reducing renal accumulation of drugs
|
|
WO2024251695A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd47 binding proteins and their use
|
|
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(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd16a binding proteins and their use
|
|
CN121263440A
(zh)
|
2023-06-06 |
2026-01-02 |
分子合作伙伴股份公司 |
重组cd2结合蛋白及其用途
|
|
WO2025068607A1
(en)
*
|
2023-09-29 |
2025-04-03 |
Universität Zürich |
Modular armadillo repeat proteins
|
|
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(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
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(en)
|
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2025-07-10 |
Molecular Partners Ag |
Multispecific binding proteins
|
|
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(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity for cd117 and cd47-binding agent
|
|
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(en)
|
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2025-07-10 |
Molecular Partners Ag |
Recombinant cd117 binding proteins and their use
|
|
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(en)
|
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2025-08-07 |
Molecular Partners Ag |
Recombinant mesothelin binding proteins and their use
|
|
US20250332297A1
(en)
|
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Molecular Partners Ag |
Dll3-specific binding constructs and their use in radiotherapy
|
|
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(en)
|
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2025-09-04 |
Molecular Partners Ag |
Therapeutic combinations comprising a multi-specific t cell engager
|
|
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(en)
|
2024-05-21 |
2025-11-27 |
Fred Hutchinson Cancer Center |
Immunotherapy cells equipped with a collagen-targeting payload
|