|
US9433684B2
(en)
|
2008-08-19 |
2016-09-06 |
Nektar Therapeutics |
Conjugates of small-interfering nucleic acids
|
|
TWI510246B
(zh)
|
2010-04-30 |
2015-12-01 |
Molecular Partners Ag |
抑制vegf-a受體交互作用的經修飾結合性蛋白質
|
|
EP3514169B1
(en)
|
2010-11-26 |
2024-03-06 |
Molecular Partners AG |
Designed repeat proteins binding to serum albumin
|
|
SI2675480T1
(sl)
|
2011-02-15 |
2019-05-31 |
Immunogen, Inc. |
Metode priprave konjugatov
|
|
WO2012177837A2
(en)
|
2011-06-21 |
2012-12-27 |
Immunogen, Inc. |
Novel maytansinoid derivatives with peptide linker and conjugates thereof
|
|
HK1211208A1
(zh)
|
2012-08-22 |
2016-05-20 |
Immunogen, Inc. |
細胞毒性苯並二氮呯衍生物
|
|
EP2738180A1
(en)
|
2012-11-30 |
2014-06-04 |
Molecular Partners AG |
Binding proteins comprising at least two binding domains against HER2.
|
|
HK1219423A1
(zh)
|
2013-02-28 |
2017-04-07 |
Immunogen, Inc. |
包含细胞结合剂及细胞毒素剂的轭合物
|
|
HK1219422A1
(zh)
|
2013-02-28 |
2017-04-07 |
Immunogen, Inc. |
包含细胞结合剂及细胞毒素剂的轭合物
|
|
WO2014194030A2
(en)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
US11453708B2
(en)
|
2013-05-31 |
2022-09-27 |
Molecular Partners Ag |
Designed ankyrin repeat proteins binding to hepatocyte growth factor
|
|
US20160250258A1
(en)
|
2013-10-31 |
2016-09-01 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
NZ759969A
(en)
|
2013-12-20 |
2022-12-23 |
Fred Hutchinson Cancer Center |
Tagged chimeric effector molecules and receptors thereof
|
|
CN106605228B
(zh)
|
2014-07-07 |
2019-08-16 |
耶达研究及发展有限公司 |
计算蛋白质设计的方法
|
|
CR20170111A
(es)
|
2014-09-03 |
2017-05-23 |
Immunogen Inc |
Derivados de benzodiazepina citotóxicos
|
|
EP3189057A1
(en)
|
2014-09-03 |
2017-07-12 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
SG11201707182WA
(en)
|
2015-03-05 |
2017-10-30 |
Hutchinson Fred Cancer Res |
Immunomodulatory fusion proteins and uses thereof
|
|
US9458211B1
(en)
|
2015-04-02 |
2016-10-04 |
Molecular Partners Ag |
Recombinant proteins that simultaneously bind HGF, VEGF-A and serum albumin, comprising ankyrin repeat domains
|
|
EP3288569A4
(en)
|
2015-04-29 |
2018-12-19 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
EP3288570A4
(en)
|
2015-04-29 |
2018-11-21 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
|
WO2017106728A2
(en)
*
|
2015-12-16 |
2017-06-22 |
University Of Washington |
Repeat protein architectures
|
|
EP4166161B1
(en)
|
2016-04-14 |
2026-03-04 |
Fred Hutchinson Cancer Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
MY196882A
(en)
|
2016-09-22 |
2023-05-08 |
Molecular Partners Ag |
Recombinant binding proteins and their use
|
|
IL268349B2
(en)
|
2017-02-17 |
2024-08-01 |
Hutchinson Fred Cancer Res |
Combination therapies for treatment of bcma-related cancers and autoimmune disorders
|
|
IL298414B2
(en)
|
2017-02-28 |
2024-12-01 |
Immunogen Inc |
Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof
|
|
WO2018165046A1
(en)
|
2017-03-07 |
2018-09-13 |
Igc Bio, Inc. |
A computational pipeline for antibody modeling and design
|
|
US11725210B2
(en)
|
2017-03-17 |
2023-08-15 |
Fred Hutchinson Cancer Center |
Immunomodulatory fusion proteins and uses thereof
|
|
WO2018195243A1
(en)
|
2017-04-20 |
2018-10-25 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives and conjugates thereof
|
|
WO2019133652A1
(en)
|
2017-12-28 |
2019-07-04 |
Immunogen, Inc. |
Benzodiazepine derivatives
|
|
EP3849565A4
(en)
|
2018-09-12 |
2022-12-28 |
Fred Hutchinson Cancer Research Center |
REDUCTION OF CD33 EXPRESSION TO SELECTIVELY PROTECT THERAPEUTIC CELLS
|
|
AU2020240310A1
(en)
|
2019-03-21 |
2021-10-07 |
Immunogen, Inc. |
Methods of preparing cell-binding agent-drug conjugates
|
|
US20230094471A1
(en)
|
2019-03-29 |
2023-03-30 |
Immunogen, Inc. |
Cytotoxic bis-benzodiazepine derivatives and conjugates thereof with cell-binding agents for inhibiting abnormal cell growth or for treating proliferative diseases
|
|
RS64961B1
(sr)
|
2019-04-26 |
2024-01-31 |
Immunogen Inc |
Derivati kamptotecina
|
|
EP3980452A1
(en)
|
2019-06-04 |
2022-04-13 |
Molecular Partners AG |
Recombinant 4-1bb binding proteins and their use
|
|
KR20220016944A
(ko)
|
2019-06-04 |
2022-02-10 |
몰리큘라 파트너스 아게 |
개선된 안정성을 갖는 설계된 안키린 반복 도메인
|
|
CA3139164A1
(en)
|
2019-06-04 |
2020-12-10 |
Molecular Partners Ag |
Recombinant fap binding proteins and their use
|
|
BR112021026832A2
(pt)
|
2019-07-02 |
2022-05-10 |
Hutchinson Fred Cancer Res |
Vetores ad35 recombinantes e aprimoramentos da terapia gênica relacionada
|
|
AU2020402581A1
(en)
|
2019-12-11 |
2022-06-23 |
Molecular Partners Ag |
Designed ankyrin repeat domains with altered surface residues
|
|
CN114945584A
(zh)
|
2019-12-11 |
2022-08-26 |
分子合作伙伴股份公司 |
重组肽-mhc复合物结合蛋白及其生成和用途
|
|
US20230142283A1
(en)
*
|
2020-03-05 |
2023-05-11 |
University Of Washington |
Rigid helical junctions for modular repeat protein sculpting and methods of use
|
|
MX2022013945A
(es)
|
2020-05-06 |
2023-02-14 |
Molecular Partners Ag |
Nuevas proteinas de union a repeticiones de anquirina y sus usos.
|
|
IL298168A
(en)
|
2020-05-14 |
2023-01-01 |
Molecular Partners Ag |
Multispecific proteins
|
|
AU2021271131A1
(en)
|
2020-05-14 |
2022-12-15 |
Molecular Partners Ag |
Recombinant CD40 binding proteins and their use
|
|
US20240108746A1
(en)
|
2020-12-16 |
2024-04-04 |
Molecular Partners Ag |
Novel slow-release prodrugs
|
|
AU2021403658A1
(en)
|
2020-12-16 |
2023-06-29 |
Molecular Partners Ag |
Recombinant cd3 binding proteins and their use
|
|
WO2022190016A1
(en)
|
2021-03-09 |
2022-09-15 |
Molecular Partners Ag |
Novel darpin based multi-specific t-cell engagers
|
|
EP4305063A1
(en)
|
2021-03-09 |
2024-01-17 |
Molecular Partners AG |
Protease cleavable prodrugs
|
|
US20240317852A1
(en)
|
2021-03-09 |
2024-09-26 |
Molecular Partners Ag |
Novel darpin based cd33 engagers
|
|
CA3211368A1
(en)
|
2021-03-09 |
2022-09-15 |
Molecular Partners Ag |
Novel darpin based cd123 engagers
|
|
WO2023110983A1
(en)
|
2021-12-14 |
2023-06-22 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity and their use
|
|
EP4460511A1
(en)
*
|
2022-01-07 |
2024-11-13 |
Universität Zürich |
Stabilizing n-cap sequences for armadillo repeat proteins
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
CA3262553A1
(en)
|
2022-08-01 |
2024-02-08 |
Molecular Partners Ag |
REHEARSAL AREAS DESIGNED WITH MODIFIED CHARGES AND THEIR USE
|
|
EP4673159A1
(en)
|
2023-02-27 |
2026-01-07 |
Molecular Partners AG |
Darpins for use in reducing renal accumulation of drugs
|
|
EP4724473A1
(en)
|
2023-06-06 |
2026-04-15 |
Molecular Partners AG |
Recombinant cd47 binding proteins and their use
|
|
WO2024251628A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd16a binding proteins and their use
|
|
JP2026524079A
(ja)
|
2023-06-06 |
2026-07-17 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
組換えcd2結合タンパク質及びその使用
|
|
EP4784597A1
(en)
*
|
2023-09-29 |
2026-08-05 |
Universität Zürich |
Modular armadillo repeat proteins
|
|
WO2025101820A1
(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2025146491A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity for cd117 and cd47-binding agent
|
|
WO2025146490A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Recombinant cd117 binding proteins and their use
|
|
CN122438868A
(zh)
|
2024-01-05 |
2026-07-21 |
分子合作伙伴股份公司 |
多特异性结合蛋白
|
|
WO2025163144A1
(en)
|
2024-01-31 |
2025-08-07 |
Molecular Partners Ag |
Recombinant mesothelin binding proteins and their use
|
|
WO2025163082A1
(en)
|
2024-01-31 |
2025-08-07 |
Molecular Partners Ag |
Dll3-specific binding constructs and their use in radiotherapy
|
|
WO2025181039A1
(en)
|
2024-03-01 |
2025-09-04 |
Molecular Partners Ag |
Therapeutic combinations comprising a multi-specific t cell engager
|
|
WO2025245169A1
(en)
|
2024-05-21 |
2025-11-27 |
Fred Hutchinson Cancer Center |
Immunotherapy cells equipped with a collagen-targeting payload
|
|
WO2026093563A2
(en)
|
2024-10-31 |
2026-05-07 |
Molecular Partners Ag |
Multispecific binding proteins and their use
|
|
WO2026150109A1
(en)
|
2025-01-10 |
2026-07-16 |
Molecular Partners Ag |
Mesothelin-specific binding constructs and their use in radiotherapy
|