ATE443161T1 - Mittel und verfahren für den nachweis von methylierter dna - Google Patents
Mittel und verfahren für den nachweis von methylierter dnaInfo
- Publication number
- ATE443161T1 ATE443161T1 AT05810547T AT05810547T ATE443161T1 AT E443161 T1 ATE443161 T1 AT E443161T1 AT 05810547 T AT05810547 T AT 05810547T AT 05810547 T AT05810547 T AT 05810547T AT E443161 T1 ATE443161 T1 AT E443161T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- polypeptide
- acid molecule
- present application
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 6
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 210000004027 cell Anatomy 0.000 abstract 2
- 102000031635 methyl-CpG binding proteins Human genes 0.000 abstract 2
- 108091009877 methyl-CpG binding proteins Proteins 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 230000004568 DNA-binding Effects 0.000 abstract 1
- 230000001588 bifunctional effect Effects 0.000 abstract 1
- 230000027455 binding Effects 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N21/00—Selective content distribution, e.g. interactive television or video on demand [VOD]
- H04N21/20—Servers specifically adapted for the distribution of content, e.g. VOD servers; Operations thereof
- H04N21/23—Processing of content or additional data; Elementary server operations; Server middleware
- H04N21/24—Monitoring of processes or resources, e.g. monitoring of server load, available bandwidth, upstream requests
- H04N21/2402—Monitoring of the downstream path of the transmission network, e.g. bandwidth available
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N21/00—Selective content distribution, e.g. interactive television or video on demand [VOD]
- H04N21/20—Servers specifically adapted for the distribution of content, e.g. VOD servers; Operations thereof
- H04N21/23—Processing of content or additional data; Elementary server operations; Server middleware
- H04N21/24—Monitoring of processes or resources, e.g. monitoring of server load, available bandwidth, upstream requests
- H04N21/2401—Monitoring of the client buffer
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/164—Methylation detection other then bisulfite or methylation sensitive restriction endonucleases
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Multimedia (AREA)
- Signal Processing (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04028267 | 2004-11-29 | ||
| PCT/EP2005/012707 WO2006056480A2 (en) | 2004-11-29 | 2005-11-28 | Means and methods for detecting methylated dna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE443161T1 true ATE443161T1 (de) | 2009-10-15 |
Family
ID=34927572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05810547T ATE443161T1 (de) | 2004-11-29 | 2005-11-28 | Mittel und verfahren für den nachweis von methylierter dna |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US9074013B2 (de) |
| EP (1) | EP1817430B1 (de) |
| JP (2) | JP5149013B2 (de) |
| CN (1) | CN101243191B (de) |
| AT (1) | ATE443161T1 (de) |
| AU (1) | AU2005308918B2 (de) |
| CA (1) | CA2589487C (de) |
| DE (1) | DE602005016712D1 (de) |
| WO (1) | WO2006056480A2 (de) |
Families Citing this family (101)
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|---|---|---|---|---|
| WO2006056480A2 (en) * | 2004-11-29 | 2006-06-01 | Klinikum Der Universität Regensburg | Means and methods for detecting methylated dna |
| CN101124338B (zh) | 2004-11-29 | 2011-05-04 | 雷根斯堡大学临床中心 | 用于检测甲基化dna的试剂盒和方法 |
| US20210371901A1 (en) * | 2004-11-29 | 2021-12-02 | Sequenom, Inc. | Kits and Methods for Detecting Methylated DNA |
| EP2029777B1 (de) | 2006-05-31 | 2017-03-08 | Sequenom, Inc. | Verfahren und zusammensetzungen zur nukleinsäureextraktion aus einer probe |
| US7902345B2 (en) | 2006-12-05 | 2011-03-08 | Sequenom, Inc. | Detection and quantification of biomolecules using mass spectrometry |
| CN101641452B (zh) | 2007-03-26 | 2013-10-23 | 塞昆纳姆股份有限公司 | 限制性核酸内切酶增强的多态序列检测 |
| JP5211790B2 (ja) * | 2007-03-26 | 2013-06-12 | 住友化学株式会社 | Dnaメチル化測定方法 |
| EP2195452B1 (de) | 2007-08-29 | 2012-03-14 | Sequenom, Inc. | Verfahren und zusammensetzungen für die universelle grössenspezifische polymerasekettenreaktion |
| US7888127B2 (en) | 2008-01-15 | 2011-02-15 | Sequenom, Inc. | Methods for reducing adduct formation for mass spectrometry analysis |
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2005
- 2005-11-28 WO PCT/EP2005/012707 patent/WO2006056480A2/en not_active Ceased
- 2005-11-28 JP JP2007541869A patent/JP5149013B2/ja not_active Expired - Lifetime
- 2005-11-28 EP EP05810547A patent/EP1817430B1/de not_active Expired - Lifetime
- 2005-11-28 CN CN200580047175.7A patent/CN101243191B/zh not_active Expired - Lifetime
- 2005-11-28 CA CA2589487A patent/CA2589487C/en not_active Expired - Lifetime
- 2005-11-28 AU AU2005308918A patent/AU2005308918B2/en not_active Expired
- 2005-11-28 AT AT05810547T patent/ATE443161T1/de not_active IP Right Cessation
- 2005-11-28 DE DE602005016712T patent/DE602005016712D1/de not_active Expired - Lifetime
- 2005-11-28 US US11/569,051 patent/US9074013B2/en active Active
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- 2012-09-24 JP JP2012209790A patent/JP2013027399A/ja active Pending
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- 2018-01-22 US US15/876,844 patent/US20180220176A1/en not_active Abandoned
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| JP5149013B2 (ja) | 2013-02-20 |
| CN101243191B (zh) | 2014-04-16 |
| WO2006056480A3 (en) | 2008-03-27 |
| US20180220176A1 (en) | 2018-08-02 |
| AU2005308918B2 (en) | 2012-09-27 |
| US9074013B2 (en) | 2015-07-07 |
| CA2589487C (en) | 2014-07-29 |
| US20210337252A1 (en) | 2021-10-28 |
| CA2589487A1 (en) | 2006-06-01 |
| US20150267263A1 (en) | 2015-09-24 |
| JP2013027399A (ja) | 2013-02-07 |
| US20080260743A1 (en) | 2008-10-23 |
| WO2006056480A2 (en) | 2006-06-01 |
| US9873919B2 (en) | 2018-01-23 |
| CN101243191A (zh) | 2008-08-13 |
| DE602005016712D1 (de) | 2009-10-29 |
| AU2005308918A1 (en) | 2006-06-01 |
| EP1817430B1 (de) | 2009-09-16 |
| JP2008521389A (ja) | 2008-06-26 |
| EP1817430A2 (de) | 2007-08-15 |
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