JP2010539915A - 設計されたアルマジロリピートタンパク質 - Google Patents

設計されたアルマジロリピートタンパク質 Download PDF

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Publication number
JP2010539915A
JP2010539915A JP2010526268A JP2010526268A JP2010539915A JP 2010539915 A JP2010539915 A JP 2010539915A JP 2010526268 A JP2010526268 A JP 2010526268A JP 2010526268 A JP2010526268 A JP 2010526268A JP 2010539915 A JP2010539915 A JP 2010539915A
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repeat
protein
armadillo
module
amino acid
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JP2010526268A
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Japanese (ja)
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JP2010539915A5 (enExample
Inventor
パルメジャーニ，ファビオ
ペラリン，リッカルド
ラルセン，アナス・ペーター
ヴァラダムセッティ，ゴーサム
シュトゥンプ，ミハエル・トビアス
プリュックトゥーン，アンドレアス
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Zurich Universität
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Zurich Universität
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Publication of JP2010539915A publication Critical patent/JP2010539915A/ja
Publication of JP2010539915A5 publication Critical patent/JP2010539915A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
JP2010526268A 2007-09-24 2008-09-23 設計されたアルマジロリピートタンパク質 Pending JP2010539915A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07117059 2007-09-24
PCT/EP2008/062671 WO2009040338A1 (en) 2007-09-24 2008-09-23 Designed armadillo repeat proteins

Publications (2)

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JP2010539915A true JP2010539915A (ja) 2010-12-24
JP2010539915A5 JP2010539915A5 (enExample) 2011-10-13

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JP2010526268A Pending JP2010539915A (ja) 2007-09-24 2008-09-23 設計されたアルマジロリピートタンパク質

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US (1) US9365629B2 (enExample)
EP (1) EP2198022B1 (enExample)
JP (1) JP2010539915A (enExample)
CA (1) CA2700391A1 (enExample)
WO (1) WO2009040338A1 (enExample)

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WO2017106728A2 (en) * 2015-12-16 2017-06-22 University Of Washington Repeat protein architectures
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US20230142283A1 (en) * 2020-03-05 2023-05-11 University Of Washington Rigid helical junctions for modular repeat protein sculpting and methods of use
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Patent Citations (1)

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JPN6013030027; Ｃｕｒｒ．　Ｏｐｉｎ．　Ｓｔｒｕｃｔ．　Ｂｉｏｌ．，　（１９９９），　９，　［３］，　ｐ．３８３-３８９ *
JPN6013030028; Ｔｒｅｎｄｓ　Ｃｅｌｌ　Ｂｉｏｌ．，　（２００３），　１３，　［９］，　ｐ．４６３-４７１ *

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US20110224100A1 (en) 2011-09-15
EP2198022B1 (en) 2024-03-06
EP2198022A1 (en) 2010-06-23
CA2700391A1 (en) 2009-04-02
EP2198022C0 (en) 2024-03-06
US9365629B2 (en) 2016-06-14
WO2009040338A1 (en) 2009-04-02

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