JP2017530099A5 - - Google Patents
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- Publication number
- JP2017530099A5 JP2017530099A5 JP2017510495A JP2017510495A JP2017530099A5 JP 2017530099 A5 JP2017530099 A5 JP 2017530099A5 JP 2017510495 A JP2017510495 A JP 2017510495A JP 2017510495 A JP2017510495 A JP 2017510495A JP 2017530099 A5 JP2017530099 A5 JP 2017530099A5
- Authority
- JP
- Japan
- Prior art keywords
- binding domain
- fzd
- signaling agonist
- signaling
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462049949P | 2014-09-12 | 2014-09-12 | |
| US62/049,949 | 2014-09-12 | ||
| US201562206150P | 2015-08-17 | 2015-08-17 | |
| US62/206,150 | 2015-08-17 | ||
| PCT/US2015/049829 WO2016040895A1 (en) | 2014-09-12 | 2015-09-11 | Wnt signaling agonist molecules |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020138446A Division JP2020186267A (ja) | 2014-09-12 | 2020-08-19 | Ｗｎｔシグナリングアゴニスト分子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530099A JP2017530099A (ja) | 2017-10-12 |
| JP2017530099A5 true JP2017530099A5 (enExample) | 2018-09-13 |
| JP6796059B2 JP6796059B2 (ja) | 2020-12-02 |
Family
ID=55459641
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017510495A Active JP6796059B2 (ja) | 2014-09-12 | 2015-09-11 | Ｗｎｔシグナリングアゴニスト分子 |
| JP2020138446A Withdrawn JP2020186267A (ja) | 2014-09-12 | 2020-08-19 | Ｗｎｔシグナリングアゴニスト分子 |
| JP2023080152A Pending JP2023091081A (ja) | 2014-09-12 | 2023-05-15 | Ｗｎｔシグナリングアゴニスト分子 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020138446A Withdrawn JP2020186267A (ja) | 2014-09-12 | 2020-08-19 | Ｗｎｔシグナリングアゴニスト分子 |
| JP2023080152A Pending JP2023091081A (ja) | 2014-09-12 | 2023-05-15 | Ｗｎｔシグナリングアゴニスト分子 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US11142577B2 (enExample) |
| EP (2) | EP4219564A1 (enExample) |
| JP (3) | JP6796059B2 (enExample) |
| AU (2) | AU2015314771B2 (enExample) |
| WO (1) | WO2016040895A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6796059B2 (ja) | 2014-09-12 | 2020-12-02 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | Ｗｎｔシグナリングアゴニスト分子 |
| US20170349659A1 (en) * | 2016-06-03 | 2017-12-07 | The Board Of Trustees Of The Leland Stanford Junior University | Wnt signaling agonist molecules |
| JP7617603B2 (ja) | 2017-01-11 | 2025-01-20 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | Ｒ－スポンジン（ｒｓｐｏ）サロゲート分子 |
| AU2018211985B2 (en) | 2017-01-26 | 2025-02-13 | Surrozen Operating, Inc. | Tissue-specific Wnt signal enhancing molecules and uses thereof |
| KR101966523B1 (ko) * | 2017-05-29 | 2019-04-05 | 차의과학대학교 산학협력단 | 오가노이드 배양을 위한 조성물 및 방법 |
| CN118271444A (zh) * | 2017-12-19 | 2024-07-02 | 瑟罗泽恩奥普瑞汀公司 | Wnt替代分子和其用途 |
| CN111699003B (zh) * | 2017-12-19 | 2024-05-03 | 瑟罗泽恩奥普瑞汀公司 | 抗lrp5/6抗体和使用方法 |
| JP7418332B2 (ja) * | 2017-12-19 | 2024-01-19 | スロゼン オペレーティング， インコーポレイテッド | 抗フリズルド抗体及び使用方法 |
| US20210032352A1 (en) * | 2018-02-14 | 2021-02-04 | Antera Therapeutics Inc. | Multivalent Binding Molecules Activating WNT Signaling and Uses Thereof |
| JP2021518113A (ja) | 2018-03-16 | 2021-08-02 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 心筋細胞を生成及び増殖させるためのｗｎｔアゴニスト、並びに生理活性脂質を用いた試薬及び方法 |
| AU2019297522B2 (en) * | 2018-07-05 | 2026-04-23 | Surrozen Operating, Inc. | Multi-specific Wnt surrogate molecules and uses thereof |
| JP2021530223A (ja) | 2018-07-09 | 2021-11-11 | スロゼン， インコーポレイテッド | 組織特異性Ｗｎｔシグナル増強分子及びその使用 |
| EP3823661A4 (en) * | 2018-07-16 | 2022-05-11 | The Board of Trustees of the Leland Stanford Junior University | SPECIFIC FRIZZLED WNT AGONISTS AND ANTAGONISTS |
| US20220064337A1 (en) * | 2018-12-19 | 2022-03-03 | Surrozen, Inc. | Antigen binding formats for receptor complexes |
| AU2020221797A1 (en) * | 2019-02-11 | 2021-08-12 | Surrozen Operating, Inc. | Modulation of WNT signalling in ocular disorders |
| WO2020185960A1 (en) * | 2019-03-11 | 2020-09-17 | Surrozen, Inc. | Modulation of wnt signaling in gastrointestinal disorders |
| KR20220024460A (ko) * | 2019-06-11 | 2022-03-03 | 안틀라 테라퓨틱스 아이엔씨. | 다가 fzd 및 wnt 결합 분자 및 이의 용도 |
| CA3144499A1 (en) | 2019-07-02 | 2021-01-07 | Surrozen Operating, Inc. | Monospecific anti-frizzled antibodies and methods of use |
| EP3789049A1 (en) | 2019-09-06 | 2021-03-10 | QGel SA | Method for obtaining healthy intestinal organoids |
| WO2022104280A1 (en) | 2020-11-16 | 2022-05-19 | Surrozen Operating, Inc. | Liver-specific wnt signal enhancing molecules and uses thereof |
| WO2022164786A1 (en) * | 2021-01-26 | 2022-08-04 | The Trustees Of Indiana University | Pharmaceutical compositions and their methods of use |
| JP7891006B2 (ja) * | 2021-03-10 | 2026-07-15 | スロゼン オペレーティング， インコーポレイテッド | 胃腸障害におけるｗｎｔシグナル伝達のモジュレーション |
| CA3240866A1 (en) * | 2021-12-17 | 2023-06-22 | Surrozen Operating, Inc. | Wnt-surrogate agents and methods for lacrimal gland regeneration |
| WO2024227103A1 (en) * | 2023-04-27 | 2024-10-31 | Surrozen Operating, Inc. | Molecules modulating wnt signaling pathways and uses thereof |
| AU2024279826A1 (en) * | 2023-05-29 | 2026-01-08 | Surrozen Operating, Inc. | Wnt surrogate agents and methods for lacrimal gland regeneration |
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| HUT72495A (en) | 1992-10-01 | 1996-05-28 | Cold Spring Harbor Lab | Complex combinatorial chemical libraries encoded with tags |
| JPH09508353A (ja) | 1993-11-02 | 1997-08-26 | アフィマックス テクノロジーズ ナムローゼ フェンノートシャップ | 分子多様性の合成及びスクリーニング |
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| EP1902318A1 (en) | 2005-05-30 | 2008-03-26 | AstraZeneca AB | Methods for identifying fzd8 modulators and the use of such modulators for treating osteoarthritis |
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| AU2009291747B2 (en) * | 2008-09-10 | 2016-05-26 | Genentech, Inc. | Methods for inhibiting ocular angiogenesis |
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| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
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| CN103501799A (zh) * | 2011-01-28 | 2014-01-08 | 莱兰斯坦福初级大学评议会 | Wnt组合物及其使用方法 |
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| CN104203981A (zh) | 2011-12-19 | 2014-12-10 | 合成免疫股份有限公司 | 双特异性抗体分子 |
| SG10201601747XA (en) | 2012-01-18 | 2016-04-28 | Genentech Inc | Anti-LRP5 Antibodies And Methods Of Use |
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| WO2014059068A1 (en) | 2012-10-11 | 2014-04-17 | The Trustees Of The University Of Pennsylvania | Methods for the treatment and prevention of osteoporosis and bone-related disorders |
| CN105073195A (zh) | 2013-02-04 | 2015-11-18 | 昂科梅德制药有限公司 | 使用Wnt途径抑制剂进行治疗的方法及对该治疗的监测 |
| HK1218930A1 (zh) | 2013-02-08 | 2017-03-17 | Abbvie Stemcentrx Llc | 新型多特异性结构 |
| CN105431161A (zh) * | 2013-02-21 | 2016-03-23 | 范安德尔研究所 | Norrin突变体多肽、其制造方法和用途 |
| JP2016512533A (ja) | 2013-03-14 | 2016-04-28 | オンコメッド ファーマシューティカルズ インコーポレイテッド | Ｍｅｔ結合剤およびその使用 |
| GB2518221A (en) | 2013-09-16 | 2015-03-18 | Sergej Michailovic Kiprijanov | Tetravalent antigen-binding protein molecule |
| GB2519786A (en) | 2013-10-30 | 2015-05-06 | Sergej Michailovic Kiprijanov | Multivalent antigen-binding protein molecules |
| JP6796059B2 (ja) | 2014-09-12 | 2020-12-02 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | Ｗｎｔシグナリングアゴニスト分子 |
| US9777052B2 (en) | 2014-12-02 | 2017-10-03 | The Board Of Regents Of The University Of Oklahoma | R-spondin variants, compositions, and methods of use |
| US20160312207A1 (en) | 2015-04-21 | 2016-10-27 | The Board Of Trustees Of The Leland Stanford Junior University | R-spondin antagonists and methods of treating cancer associated with aberrant activation of wnt signaling |
-
2015
- 2015-09-11 JP JP2017510495A patent/JP6796059B2/ja active Active
- 2015-09-11 EP EP23157332.0A patent/EP4219564A1/en not_active Withdrawn
- 2015-09-11 AU AU2015314771A patent/AU2015314771B2/en active Active
- 2015-09-11 US US15/508,779 patent/US11142577B2/en active Active
- 2015-09-11 EP EP15840226.3A patent/EP3191526B1/en active Active
- 2015-09-11 WO PCT/US2015/049829 patent/WO2016040895A1/en not_active Ceased
-
2020
- 2020-08-19 JP JP2020138446A patent/JP2020186267A/ja not_active Withdrawn
-
2021
- 2021-05-13 AU AU2021203059A patent/AU2021203059A1/en not_active Abandoned
- 2021-09-08 US US17/469,661 patent/US20210403578A1/en not_active Abandoned
-
2023
- 2023-05-15 JP JP2023080152A patent/JP2023091081A/ja active Pending
-
2024
- 2024-04-04 US US18/627,108 patent/US20250011437A1/en not_active Abandoned
-
2025
- 2025-03-03 US US19/069,060 patent/US20250304702A1/en not_active Abandoned
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