JP6796059B2 - Ｗｎｔシグナリングアゴニスト分子 - Google Patents

Ｗｎｔシグナリングアゴニスト分子 Download PDF

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JP6796059B2
JP6796059B2 JP2017510495A JP2017510495A JP6796059B2 JP 6796059 B2 JP6796059 B2 JP 6796059B2 JP 2017510495 A JP2017510495 A JP 2017510495A JP 2017510495 A JP2017510495 A JP 2017510495A JP 6796059 B2 JP6796059 B2 JP 6796059B2
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binding domain
wnt
wnt signaling
fzd
cells
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JP2017530099A (ja
JP2017530099A5 (enExample
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クリストファー ガルシア，ケナン
クリストファー ガルシア，ケナン
デイビッド ベイカー，
デイビッド ベイカー，
クラウディア イヴォンヌ ジャンダ，
クラウディア イヴォンヌ ジャンダ，
ルーク ダン，
ルーク ダン，
ジェイムズ ダニエル ムーディー，
ジェイムズ ダニエル ムーディー，
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Leland Stanford Junior University
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Leland Stanford Junior University
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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JP2017510495A 2014-09-12 2015-09-11 Ｗｎｔシグナリングアゴニスト分子 Active JP6796059B2 (ja)

Applications Claiming Priority (5)

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US201462049949P 2014-09-12 2014-09-12
US62/049,949 2014-09-12
US201562206150P 2015-08-17 2015-08-17
US62/206,150 2015-08-17
PCT/US2015/049829 WO2016040895A1 (en) 2014-09-12 2015-09-11 Wnt signaling agonist molecules

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JP2017530099A JP2017530099A (ja) 2017-10-12
JP2017530099A5 JP2017530099A5 (enExample) 2018-09-13
JP6796059B2 true JP6796059B2 (ja) 2020-12-02

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JP2020138446A Withdrawn JP2020186267A (ja) 2014-09-12 2020-08-19 Ｗｎｔシグナリングアゴニスト分子
JP2023080152A Pending JP2023091081A (ja) 2014-09-12 2023-05-15 Ｗｎｔシグナリングアゴニスト分子

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JP2023080152A Pending JP2023091081A (ja) 2014-09-12 2023-05-15 Ｗｎｔシグナリングアゴニスト分子

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US (4) US11142577B2 (enExample)
EP (2) EP3191526B1 (enExample)
JP (3) JP6796059B2 (enExample)
AU (2) AU2015314771B2 (enExample)
CA (1) CA2959045A1 (enExample)
WO (1) WO2016040895A1 (enExample)

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AU2018207440B2 (en) 2017-01-11 2022-06-02 The Board Of Trustees Of The Leland Stanford Junior University R-spondin (RSPO) surrogate molecules
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CN112566940B (zh) * 2018-07-05 2025-06-13 瑟罗泽恩奥普瑞汀公司 多特异性wnt替代分子和其用途
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US20220064337A1 (en) * 2018-12-19 2022-03-03 Surrozen, Inc. Antigen binding formats for receptor complexes
KR20210128434A (ko) * 2019-02-11 2021-10-26 서로젠, 인크. 안구 장애에서의 wnt 신호 전달의 조절
JP2022525300A (ja) * 2019-03-11 2022-05-12 スロゼン オペレーティング， インコーポレイテッド 胃腸障害におけるｗｎｔシグナル伝達の調節
JP7377288B2 (ja) * 2019-06-11 2023-11-09 アントレラ セラピューティクス インコーポレイテッド 多価ｆｚｄおよびｗｎｔ結合分子とその使用
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TW202233656A (zh) 2020-11-16 2022-09-01 美商蘇羅森營運公司 肝特異性wnt訊號增強分子及其用途
US20240150473A1 (en) * 2021-03-10 2024-05-09 Surrozen Operating, Inc. Modulation of wnt signaling in gastrointestinal disorders
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