JP2010527346A5 - - Google Patents
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- Publication number
- JP2010527346A5 JP2010527346A5 JP2010507981A JP2010507981A JP2010527346A5 JP 2010527346 A5 JP2010527346 A5 JP 2010527346A5 JP 2010507981 A JP2010507981 A JP 2010507981A JP 2010507981 A JP2010507981 A JP 2010507981A JP 2010527346 A5 JP2010527346 A5 JP 2010527346A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- phenylpyrrolidin
- quinolin
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0709489.9 | 2007-05-17 | ||
| GB0709489A GB0709489D0 (en) | 2007-05-17 | 2007-05-17 | New use |
| GB0807591A GB0807591D0 (en) | 2008-04-25 | 2008-04-25 | New use |
| GB0807591.3 | 2008-04-25 | ||
| PCT/GB2008/001694 WO2008142384A1 (en) | 2007-05-17 | 2008-05-16 | Use of 4-(pyrrolidin-1-yl)quinoline compounds to kill clinically latent microorganisms |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010527346A JP2010527346A (ja) | 2010-08-12 |
| JP2010527346A5 true JP2010527346A5 (https=) | 2011-06-30 |
| JP5474768B2 JP5474768B2 (ja) | 2014-04-16 |
Family
ID=39672613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010507981A Expired - Fee Related JP5474768B2 (ja) | 2007-05-17 | 2008-05-16 | 臨床的に潜伏性の微生物を殺傷するための４−（ピロリジン−１−イル）キノリン化合物の使用 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8759348B2 (https=) |
| EP (1) | EP2182950B8 (https=) |
| JP (1) | JP5474768B2 (https=) |
| KR (1) | KR101599384B1 (https=) |
| CN (1) | CN101795688B (https=) |
| AU (1) | AU2008252636B2 (https=) |
| BR (1) | BRPI0811745B1 (https=) |
| CA (1) | CA2684692C (https=) |
| DK (1) | DK2182950T3 (https=) |
| ES (1) | ES2637999T3 (https=) |
| HR (1) | HRP20171553T1 (https=) |
| HU (1) | HUE034298T2 (https=) |
| IL (1) | IL201392A (https=) |
| MX (1) | MX2009012390A (https=) |
| NZ (1) | NZ580625A (https=) |
| PL (1) | PL2182950T3 (https=) |
| PT (1) | PT2182950T (https=) |
| RU (1) | RU2520766C2 (https=) |
| SI (1) | SI2182950T1 (https=) |
| WO (1) | WO2008142384A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010095522A (ja) * | 2008-09-19 | 2010-04-30 | Sumitomo Chemical Co Ltd | 植物病原菌による植物病害を防除又は予防するための農業用組成物 |
| ES2703253T3 (es) * | 2010-03-30 | 2019-03-07 | Helperby Therapeutics Ltd | Nueva combinación y uso |
| CA2798325A1 (en) * | 2010-05-13 | 2011-11-17 | Amgen Inc. | Heteroaryloxyheterocyclyl compounds as pde10 inhibitors |
| DK2600869T3 (da) | 2010-08-05 | 2020-11-16 | Helperby Therapeutics Ltd | Kombination af en pyrroloquinolinforbindelse og et beta-lactam-antimikrobielt middel, mupirocin eller chlorhexidin |
| GB201013207D0 (en) | 2010-08-05 | 2010-09-22 | Helperby Therapeutics Ltd | Novel combination |
| GB201015079D0 (en) | 2010-09-10 | 2010-10-27 | Helperby Therapeutics Ltd | Novel use |
| HK1250679A1 (zh) | 2015-04-11 | 2019-01-11 | Helperby Therapeutics Limited | 口腔用组合物 |
| WO2017027768A1 (en) | 2015-08-13 | 2017-02-16 | The Broad Institute, Inc. | Compositions and methods for treating tuberculosis |
| GB201518969D0 (en) | 2015-10-27 | 2015-12-09 | Helperby Therapeutics Ltd | Triple combination |
| WO2017120225A1 (en) * | 2016-01-04 | 2017-07-13 | The Johns Hopkins University | Use of low dose emetine for inhibition of human cytomegalovirus (hcmv) |
| KR102665309B1 (ko) * | 2016-10-27 | 2024-05-10 | 주식회사 엘지생활건강 | 코디세핀을 포함하는 구강질환 예방 또는 치료용 조성물 |
| GB201703898D0 (en) | 2017-03-10 | 2017-04-26 | Helperby Therapeautics Ltd | Method |
| RU2664177C1 (ru) * | 2017-08-07 | 2018-08-15 | федеральное государственное бюджетное образовательное учреждение высшего образования "Омский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО ОмГМУ Минздрава России) | Способ лечения абсцедирующих фурункулов верхней и нижней зон лица |
| WO2019036657A1 (en) | 2017-08-17 | 2019-02-21 | Kyn Therapeutics | AHR INHIBITORS AND USES THEREOF |
| CA3086082A1 (en) * | 2017-12-18 | 2019-06-27 | Ansella Therapeutics, Inc. | Compositions and methods for preventing and treating conditions |
| CN110897032B (zh) * | 2019-11-19 | 2025-10-14 | 华南理工大学 | 一种发酵饲料蛋白及其制备方法与应用 |
| RU2758056C2 (ru) * | 2019-11-21 | 2021-10-26 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" | Препарат для лечения отитов бактериальной и грибковой этиологии у собак |
| CN111544599B (zh) * | 2020-07-10 | 2020-12-01 | 有术肌肤管理(深圳)有限公司 | 一种用于治疗痤疮的化合物及其用于制备药物或化妆品的用途 |
| KR102461715B1 (ko) * | 2020-10-12 | 2022-11-02 | 대한민국 | 항균 및 항진균 활성을 나타내는 신균주 페니실리움 비세티 및 이의 용도 |
| CN114831924A (zh) * | 2021-03-17 | 2022-08-02 | 武汉恒信源药业有限公司 | 一种乌洛托品及其化合物的阴道局部给药制剂及用途 |
| CN113528388A (zh) * | 2021-07-19 | 2021-10-22 | 海南大学 | 珊瑚共生链霉菌、发酵生产放线菌素d的方法及应用 |
| FI4426434T3 (fi) | 2021-11-02 | 2025-11-24 | Flare Therapeutics Inc | Pparg:n käänteisagonisteja ja niiden käyttöjä |
| UY40234A (es) | 2022-04-22 | 2023-11-15 | Vertex Pharma | Compuestos heteroarilo para el tratamiento del dolor |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW477787B (en) * | 1996-08-27 | 2002-03-01 | Pfizer | Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same |
| US7074801B1 (en) | 2001-04-26 | 2006-07-11 | Eisai Co., Ltd. | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof |
| MXPA03010565A (es) * | 2001-05-21 | 2004-03-02 | Hoffmann La Roche | Derivados de quinolina como ligandos para receptor del neuropeptido y. |
| US6787558B2 (en) * | 2001-09-28 | 2004-09-07 | Hoffmann-La Roche Inc. | Quinoline derivatives |
| AU2002352868A1 (en) * | 2001-11-27 | 2003-06-10 | Merck & Co., Inc. | 4-aminoquinoline compounds |
| BR0307441A (pt) * | 2002-02-04 | 2005-01-04 | Hoffmann La Roche | Compostos, processo para a preparação de um composto, composição farmacêutica, utilização desses compostos, método para o tratamento e profilaxia de enfermidades e método para o tratamento de obesidade |
| WO2004002960A1 (en) * | 2002-06-27 | 2004-01-08 | Schering Aktiengesellschaft | Substituted quinoline ccr5 receptor antagonists |
| KR101189471B1 (ko) * | 2002-08-19 | 2012-10-12 | 아미트 모르 | 고유 수용성 및 운동 감각성 부츠 |
| WO2004035569A2 (de) * | 2002-10-10 | 2004-04-29 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Neue verbindungen mit antibakterieller aktivität |
| CL2004000409A1 (es) | 2003-03-03 | 2005-01-07 | Vertex Pharma | Compuestos derivados de 2-(cilo sustituido)-1-(amino u oxi sustituido)-quinazolina, inhibidores de canales ionicos de sodio y calcio dependientes de voltaje; composicion farmaceutica; y uso del compuesto en el tratamiento de dolor agudo, cronico, neu |
| DE102004041163A1 (de) * | 2004-08-25 | 2006-03-02 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
| US7880002B2 (en) | 2004-12-29 | 2011-02-01 | Millennium Pharmaceuticals, Inc. | Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists |
| US20060183763A1 (en) * | 2004-12-31 | 2006-08-17 | Pfizer Inc | Novel pyrrolidyl derivatives of heteroaromatic compounds |
| GB0522715D0 (en) * | 2005-11-08 | 2005-12-14 | Helperby Therapeutics Ltd | New use |
-
2008
- 2008-05-16 PL PL08750626T patent/PL2182950T3/pl unknown
- 2008-05-16 PT PT87506267T patent/PT2182950T/pt unknown
- 2008-05-16 WO PCT/GB2008/001694 patent/WO2008142384A1/en not_active Ceased
- 2008-05-16 JP JP2010507981A patent/JP5474768B2/ja not_active Expired - Fee Related
- 2008-05-16 HU HUE08750626A patent/HUE034298T2/en unknown
- 2008-05-16 HR HRP20171553TT patent/HRP20171553T1/hr unknown
- 2008-05-16 RU RU2009146828/15A patent/RU2520766C2/ru not_active IP Right Cessation
- 2008-05-16 EP EP08750626.7A patent/EP2182950B8/en not_active Not-in-force
- 2008-05-16 BR BRPI0811745-4A patent/BRPI0811745B1/pt not_active IP Right Cessation
- 2008-05-16 KR KR1020097026394A patent/KR101599384B1/ko not_active Expired - Fee Related
- 2008-05-16 MX MX2009012390A patent/MX2009012390A/es active IP Right Grant
- 2008-05-16 ES ES08750626.7T patent/ES2637999T3/es active Active
- 2008-05-16 SI SI200831883T patent/SI2182950T1/en unknown
- 2008-05-16 DK DK08750626.7T patent/DK2182950T3/da active
- 2008-05-16 CN CN200880016456.XA patent/CN101795688B/zh not_active Expired - Fee Related
- 2008-05-16 US US12/600,470 patent/US8759348B2/en not_active Expired - Fee Related
- 2008-05-16 CA CA2684692A patent/CA2684692C/en not_active Expired - Fee Related
- 2008-05-16 AU AU2008252636A patent/AU2008252636B2/en not_active Ceased
- 2008-05-16 NZ NZ580625A patent/NZ580625A/en not_active IP Right Cessation
-
2009
- 2009-10-11 IL IL201392A patent/IL201392A/en active IP Right Grant
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