JP2010527346A5 - - Google Patents
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- Publication number
- JP2010527346A5 JP2010527346A5 JP2010507981A JP2010507981A JP2010527346A5 JP 2010527346 A5 JP2010527346 A5 JP 2010527346A5 JP 2010507981 A JP2010507981 A JP 2010507981A JP 2010507981 A JP2010507981 A JP 2010507981A JP 2010527346 A5 JP2010527346 A5 JP 2010527346A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- phenylpyrrolidin
- quinolin
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0709489A GB0709489D0 (en) | 2007-05-17 | 2007-05-17 | New use |
| GB0709489.9 | 2007-05-17 | ||
| GB0807591A GB0807591D0 (en) | 2008-04-25 | 2008-04-25 | New use |
| GB0807591.3 | 2008-04-25 | ||
| PCT/GB2008/001694 WO2008142384A1 (en) | 2007-05-17 | 2008-05-16 | Use of 4-(pyrrolidin-1-yl)quinoline compounds to kill clinically latent microorganisms |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010527346A JP2010527346A (ja) | 2010-08-12 |
| JP2010527346A5 true JP2010527346A5 (https=) | 2011-06-30 |
| JP5474768B2 JP5474768B2 (ja) | 2014-04-16 |
Family
ID=39672613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010507981A Expired - Fee Related JP5474768B2 (ja) | 2007-05-17 | 2008-05-16 | 臨床的に潜伏性の微生物を殺傷するための４−（ピロリジン−１−イル）キノリン化合物の使用 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8759348B2 (https=) |
| EP (1) | EP2182950B8 (https=) |
| JP (1) | JP5474768B2 (https=) |
| KR (1) | KR101599384B1 (https=) |
| CN (1) | CN101795688B (https=) |
| AU (1) | AU2008252636B2 (https=) |
| BR (1) | BRPI0811745B1 (https=) |
| CA (1) | CA2684692C (https=) |
| DK (1) | DK2182950T3 (https=) |
| ES (1) | ES2637999T3 (https=) |
| HR (1) | HRP20171553T1 (https=) |
| HU (1) | HUE034298T2 (https=) |
| IL (1) | IL201392A (https=) |
| MX (1) | MX2009012390A (https=) |
| NZ (1) | NZ580625A (https=) |
| PL (1) | PL2182950T3 (https=) |
| PT (1) | PT2182950T (https=) |
| RU (1) | RU2520766C2 (https=) |
| SI (1) | SI2182950T1 (https=) |
| WO (1) | WO2008142384A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010095522A (ja) * | 2008-09-19 | 2010-04-30 | Sumitomo Chemical Co Ltd | 植物病原菌による植物病害を防除又は予防するための農業用組成物 |
| ES2703253T3 (es) * | 2010-03-30 | 2019-03-07 | Helperby Therapeutics Ltd | Nueva combinación y uso |
| JP2013526546A (ja) * | 2010-05-13 | 2013-06-24 | アムジエン・インコーポレーテツド | Ｐｄｅ１０阻害剤としてのヘテロアリ−ルオキシヘテロシクリル化合物 |
| WO2012017215A1 (en) | 2010-08-05 | 2012-02-09 | Helperby Therapeutics Limited | Combination of a pyrroloquinoline compound and a beta-lactam antimicrobial agent, mupirocin or chlorhexidine |
| GB201013207D0 (en) | 2010-08-05 | 2010-09-22 | Helperby Therapeutics Ltd | Novel combination |
| GB201015079D0 (en) | 2010-09-10 | 2010-10-27 | Helperby Therapeutics Ltd | Novel use |
| HK1250679A1 (zh) | 2015-04-11 | 2019-01-11 | Helperby Therapeutics Limited | 口腔用组合物 |
| US10329257B2 (en) | 2015-08-13 | 2019-06-25 | The Broad Institute, Inc. | Compositions and methods for treating tuberculosis |
| GB201518969D0 (en) | 2015-10-27 | 2015-12-09 | Helperby Therapeutics Ltd | Triple combination |
| US11253511B2 (en) | 2016-01-04 | 2022-02-22 | The Johns Hopkins University | Use of low dose emetine for inhibition of human cytomegalovirus (HCMV) |
| KR102665309B1 (ko) * | 2016-10-27 | 2024-05-10 | 주식회사 엘지생활건강 | 코디세핀을 포함하는 구강질환 예방 또는 치료용 조성물 |
| GB201703898D0 (en) | 2017-03-10 | 2017-04-26 | Helperby Therapeautics Ltd | Method |
| RU2664177C1 (ru) * | 2017-08-07 | 2018-08-15 | федеральное государственное бюджетное образовательное учреждение высшего образования "Омский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО ОмГМУ Минздрава России) | Способ лечения абсцедирующих фурункулов верхней и нижней зон лица |
| BR112020003116A2 (pt) | 2017-08-17 | 2020-08-04 | Ikena Oncology, Inc. | inibidores de ahr e usos dos mesmos |
| CN111655262A (zh) | 2017-12-18 | 2020-09-11 | 安塞拉治疗公司 | 用于预防和治疗病症的组合物及方法 |
| CN110897032B (zh) * | 2019-11-19 | 2025-10-14 | 华南理工大学 | 一种发酵饲料蛋白及其制备方法与应用 |
| RU2758056C2 (ru) * | 2019-11-21 | 2021-10-26 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" | Препарат для лечения отитов бактериальной и грибковой этиологии у собак |
| CN111544599B (zh) * | 2020-07-10 | 2020-12-01 | 有术肌肤管理(深圳)有限公司 | 一种用于治疗痤疮的化合物及其用于制备药物或化妆品的用途 |
| KR102461715B1 (ko) * | 2020-10-12 | 2022-11-02 | 대한민국 | 항균 및 항진균 활성을 나타내는 신균주 페니실리움 비세티 및 이의 용도 |
| CN114831924A (zh) * | 2021-03-17 | 2022-08-02 | 武汉恒信源药业有限公司 | 一种乌洛托品及其化合物的阴道局部给药制剂及用途 |
| CN113528388A (zh) * | 2021-07-19 | 2021-10-22 | 海南大学 | 珊瑚共生链霉菌、发酵生产放线菌素d的方法及应用 |
| PT4426434T (pt) | 2021-11-02 | 2025-11-24 | Flare Therapeutics Inc | Agonistas inversos de pparg e suas utilizações |
| WO2023205463A1 (en) | 2022-04-22 | 2023-10-26 | Vertex Pharmaceuticals Incorporated | Heteroaryl compounds for the treatment of pain |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW477787B (en) * | 1996-08-27 | 2002-03-01 | Pfizer | Pyrido six-membered nitrogen-containing cyclic ring derivatives having corticotropin releasing factor antagonist activity and pharmaceutical composition containing same |
| US7074801B1 (en) * | 2001-04-26 | 2006-07-11 | Eisai Co., Ltd. | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof |
| JP3715280B2 (ja) | 2001-05-21 | 2005-11-09 | エフ．ホフマン−ラ ロシュ アーゲー | ニューロペプチドｙレセプターのリガンドとしてのキノリン誘導体 |
| US6787558B2 (en) * | 2001-09-28 | 2004-09-07 | Hoffmann-La Roche Inc. | Quinoline derivatives |
| CA2468159A1 (en) * | 2001-11-27 | 2003-06-05 | Merck & Co., Inc. | 4-aminoquinoline compounds |
| WO2003066055A1 (en) * | 2002-02-04 | 2003-08-14 | F. Hoffmann-La Roche Ag | Quinoline derivatives as npy antagonists |
| BR0312204A (pt) * | 2002-06-27 | 2005-04-26 | Schering Ag | Antagonista de receptor ccr5 de quinolina substituìda |
| JP2005536247A (ja) * | 2002-08-19 | 2005-12-02 | アヴィ・エルバズ | 身体位置感覚／運動感覚装置及び方法 |
| EP1551829B1 (de) * | 2002-10-10 | 2010-04-07 | Morphochem Aktiengesellschaft Für Kombinatorische Chemie | Neue verbindungen mit antibakterieller aktivität |
| CL2004000409A1 (es) | 2003-03-03 | 2005-01-07 | Vertex Pharma | Compuestos derivados de 2-(cilo sustituido)-1-(amino u oxi sustituido)-quinazolina, inhibidores de canales ionicos de sodio y calcio dependientes de voltaje; composicion farmaceutica; y uso del compuesto en el tratamiento de dolor agudo, cronico, neu |
| DE102004041163A1 (de) * | 2004-08-25 | 2006-03-02 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
| WO2006071875A1 (en) | 2004-12-29 | 2006-07-06 | Millennium Pharmaceuticals, Inc. | Compounds useful as chemokine receptor antagonists |
| US20060183763A1 (en) | 2004-12-31 | 2006-08-17 | Pfizer Inc | Novel pyrrolidyl derivatives of heteroaromatic compounds |
| GB0522715D0 (en) * | 2005-11-08 | 2005-12-14 | Helperby Therapeutics Ltd | New use |
-
2008
- 2008-05-16 ES ES08750626.7T patent/ES2637999T3/es active Active
- 2008-05-16 PT PT87506267T patent/PT2182950T/pt unknown
- 2008-05-16 JP JP2010507981A patent/JP5474768B2/ja not_active Expired - Fee Related
- 2008-05-16 DK DK08750626.7T patent/DK2182950T3/da active
- 2008-05-16 NZ NZ580625A patent/NZ580625A/en not_active IP Right Cessation
- 2008-05-16 CA CA2684692A patent/CA2684692C/en not_active Expired - Fee Related
- 2008-05-16 BR BRPI0811745-4A patent/BRPI0811745B1/pt not_active IP Right Cessation
- 2008-05-16 KR KR1020097026394A patent/KR101599384B1/ko not_active Expired - Fee Related
- 2008-05-16 WO PCT/GB2008/001694 patent/WO2008142384A1/en not_active Ceased
- 2008-05-16 HR HRP20171553TT patent/HRP20171553T1/hr unknown
- 2008-05-16 EP EP08750626.7A patent/EP2182950B8/en not_active Not-in-force
- 2008-05-16 HU HUE08750626A patent/HUE034298T2/en unknown
- 2008-05-16 AU AU2008252636A patent/AU2008252636B2/en not_active Ceased
- 2008-05-16 SI SI200831883T patent/SI2182950T1/en unknown
- 2008-05-16 PL PL08750626T patent/PL2182950T3/pl unknown
- 2008-05-16 RU RU2009146828/15A patent/RU2520766C2/ru not_active IP Right Cessation
- 2008-05-16 CN CN200880016456.XA patent/CN101795688B/zh not_active Expired - Fee Related
- 2008-05-16 MX MX2009012390A patent/MX2009012390A/es active IP Right Grant
- 2008-05-16 US US12/600,470 patent/US8759348B2/en not_active Expired - Fee Related
-
2009
- 2009-10-11 IL IL201392A patent/IL201392A/en active IP Right Grant
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