JP2010522170A - ４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法 - Google Patents

４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法 Download PDF

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Publication number
JP2010522170A
JP2010522170A JP2009554563A JP2009554563A JP2010522170A JP 2010522170 A JP2010522170 A JP 2010522170A JP 2009554563 A JP2009554563 A JP 2009554563A JP 2009554563 A JP2009554563 A JP 2009554563A JP 2010522170 A JP2010522170 A JP 2010522170A
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mmol
compound
disease
mixture
limited
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Japanese (ja)
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ルチェルマン，アレクサンダー，エル．
ミュラー，ジョージ，ダブリュ．
マン，ホン−ワ
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Celgene Corp
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Celgene Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/47—Quinolines; Isoquinolines
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  • Heart & Thoracic Surgery (AREA)
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  • Ophthalmology & Optometry (AREA)
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JP2009554563A 2007-03-20 2008-03-19 ４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法 Withdrawn JP2010522170A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91932307P 2007-03-20 2007-03-20
PCT/US2008/003602 WO2008115516A2 (en) 2007-03-20 2008-03-19 4'-o-substituted isoindoline derivatives and compositions comprising and methods of using the same

Related Child Applications (1)

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JP2014129790A Division JP5927241B2 (ja) 2007-03-20 2014-06-25 ４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法

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JP2010522170A true JP2010522170A (ja) 2010-07-01

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JP2009554563A Withdrawn JP2010522170A (ja) 2007-03-20 2008-03-19 ４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法
JP2014129790A Active JP5927241B2 (ja) 2007-03-20 2014-06-25 ４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法
JP2015211991A Active JP6373818B2 (ja) 2007-03-20 2015-10-28 ４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法
JP2017155657A Active JP6448726B2 (ja) 2007-03-20 2017-08-10 ４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法

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JP2014129790A Active JP5927241B2 (ja) 2007-03-20 2014-06-25 ４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法
JP2015211991A Active JP6373818B2 (ja) 2007-03-20 2015-10-28 ４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法
JP2017155657A Active JP6448726B2 (ja) 2007-03-20 2017-08-10 ４’−ｏ−置換イソインドリン誘導体および該誘導体を含有する組成物およびその使用方法

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Country Link
US (6) US8153659B2 (enExample)
EP (2) EP2142534B1 (enExample)
JP (4) JP2010522170A (enExample)
KR (3) KR20170093996A (enExample)
CN (2) CN101679380A (enExample)
AR (1) AR065810A1 (enExample)
AU (1) AU2008229383B2 (enExample)
BR (1) BRPI0809011A8 (enExample)
CA (1) CA2681633C (enExample)
CL (1) CL2008000805A1 (enExample)
CO (1) CO6231033A2 (enExample)
CR (2) CR11036A (enExample)
EC (1) ECSP099663A (enExample)
ES (2) ES2601131T3 (enExample)
IL (1) IL200990A (enExample)
MX (1) MX2009010082A (enExample)
MY (1) MY180812A (enExample)
NI (1) NI200900170A (enExample)
NZ (2) NZ579890A (enExample)
PE (1) PE20081894A1 (enExample)
RU (1) RU2471794C2 (enExample)
UA (1) UA97976C2 (enExample)
UY (1) UY30977A1 (enExample)
WO (1) WO2008115516A2 (enExample)
ZA (1) ZA200906497B (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017533955A (ja) * 2014-10-30 2017-11-16 カンプー バイオファーマシューティカルズ リミテッド イソインドリン誘導体、その中間体、製造方法、薬物組成物及び応用
JP2021524484A (ja) * 2018-07-10 2021-09-13 ノバルティス アーゲー ３−（５−ヒドロキシ−１−オキソイソインドリン−２−イル）ピペリジン−２，６−ジオン誘導体及びＩｋａｒｏｓファミリージンクフィンガー２（ＩＫＺＦ２）依存性疾患の処置におけるその使用
JP2022503942A (ja) * 2018-09-30 2022-01-12 上海 インスティテュート オブ マテリア メディカ、チャイニーズ アカデミー オブ サイエンシーズ イソインドリン化合物、その調製方法、医薬組成物および使用
JP2022521227A (ja) * 2019-02-22 2022-04-06 エルケム・シリコーンズ・ユーエスエイ・コーポレーション 有効成分の溶出を改善するための薬デリバリーシリコーン組成物
JP2023525951A (ja) * 2020-02-25 2023-06-20 シャンハイテック ユニバーシティ グルタルイミド骨格に基づく化合物及びその使用

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JP2929331B2 (ja) * 1990-07-18 1999-08-03 丸善石油化学株式会社 トラクションドライブ用流体
KR20070090227A (ko) * 2004-12-01 2007-09-05 셀진 코포레이션 면역조절 화합물을 포함하는 조성물 및 이의 면역결핍성장애의 치료를 위한 용도
EP2142534B1 (en) * 2007-03-20 2016-08-10 Celgene Corporation 4'-o-substituted isoindoline derivatives and compositions comprising and methods of using the same
CA2710196A1 (en) 2007-12-20 2009-07-09 Celgene Corporation Use of micro-rna as a biomarker of immunomodulatory drug activity
CA2781888C (en) 2009-12-11 2019-06-18 Nono Inc. Agents and methods for treating ischemic and other diseases
TR201903027T4 (tr) 2010-02-11 2019-03-21 Celgene Corp Arilmetoksi izoindolin türevleri ve bunları içeren kompozisyonlar ve bunları kullanma yöntemleri.
AU2013245487B2 (en) * 2010-02-11 2016-03-10 Celgene Corporation Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
AU2016203826B2 (en) * 2010-02-11 2018-05-17 Celgene Corporation Arylmethoxy isoindoline derivatives and compositions comprising and methods of using the same
AU2012236655B2 (en) * 2011-03-28 2016-09-22 Deuterx, Llc, 2',6'-dioxo-3'-deutero-piperdin-3-yl-isoindoline compounds
US9334256B2 (en) 2011-06-15 2016-05-10 Nono Inc. Agents and methods for treating ischemic and other diseases
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