|
WO2005017207A2
(en)
*
|
2003-08-14 |
2005-02-24 |
Case Western Reserve University |
Methods and compositions for detecting colon cancers
|
|
US8415100B2
(en)
|
2003-08-14 |
2013-04-09 |
Case Western Reserve University |
Methods and compositions for detecting gastrointestinal and other cancers
|
|
US12366585B2
(en)
|
2006-05-18 |
2025-07-22 |
Caris Mpi, Inc. |
Molecular profiling of tumors
|
|
GB0700374D0
(en)
*
|
2007-01-09 |
2007-02-14 |
Oncomethylome Sciences S A |
NDRG family methylation markers
|
|
CN101688239A
(zh)
*
|
2007-02-12 |
2010-03-31 |
约翰·霍普金斯大学 |
结肠癌的早期检测和预后
|
|
CA2699853A1
(en)
*
|
2007-09-17 |
2009-03-26 |
Oncomethylome Sciences Sa |
Improved detection of mage-a expression
|
|
ES2522542T3
(es)
|
2008-02-15 |
2014-11-17 |
Mayo Foundation For Medical Education And Research |
Detección de neoplasia a partir de una muestra de heces
|
|
WO2009105549A2
(en)
*
|
2008-02-19 |
2009-08-27 |
Oncomethylome Sciences Sa |
Detection and prognosis of lung cancer
|
|
EP2271774B1
(en)
|
2008-03-21 |
2018-03-07 |
MDxHealth |
Detection and prognosis of cervical cancer
|
|
CN102089444A
(zh)
|
2008-05-14 |
2011-06-08 |
德玛泰克国际公司 |
利用核酸分析方法来诊断黑素瘤和太阳能雀斑
|
|
WO2010033371A2
(en)
*
|
2008-09-22 |
2010-03-25 |
Advpharma, Inc. |
Molecular markers for lung and colorectal carcinomas
|
|
DK2394170T3
(en)
|
2009-02-03 |
2015-07-13 |
Mdxhealth Sa |
Methods for detecting colorectal cancer
|
|
WO2010102823A1
(en)
*
|
2009-03-13 |
2010-09-16 |
Oncomethylome Sciences Sa |
Novel markers for bladder cancer detection
|
|
CA2779223A1
(en)
|
2009-10-27 |
2011-05-12 |
Caris Mpi, Inc. |
Molecular profiling for personalized medicine
|
|
EP2354242A1
(en)
*
|
2010-02-03 |
2011-08-10 |
Epiontis GmbH |
Assay for determining the type and/or status of a cell based on the epigenetic pattern and the chromatin structure
|
|
CA2790416C
(en)
|
2010-03-26 |
2017-05-23 |
Mayo Foundation For Medical Education And Research |
Methods and materials for detecting colorectal neoplasm
|
|
WO2011135058A2
(en)
|
2010-04-30 |
2011-11-03 |
Mdxhealth Sa |
Methods for detecting epigenetic modifications
|
|
EP2569452B1
(en)
*
|
2010-05-14 |
2020-03-25 |
Life Technologies Corporation |
Karyotyping assay
|
|
JP5838557B2
(ja)
*
|
2010-07-05 |
2016-01-06 |
ソニー株式会社 |
生体情報処理方法および装置、並びに記録媒体
|
|
JP6222202B2
(ja)
*
|
2010-07-05 |
2017-11-01 |
ソニー株式会社 |
生体情報処理方法および装置、並びに記録媒体
|
|
US8361720B2
(en)
|
2010-11-15 |
2013-01-29 |
Exact Sciences Corporation |
Real time cleavage assay
|
|
US8916344B2
(en)
|
2010-11-15 |
2014-12-23 |
Exact Sciences Corporation |
Methylation assay
|
|
EP3441479B1
(en)
*
|
2011-02-02 |
2020-09-02 |
Exact Sciences Development Company, LLC |
Digital sequence analysis of dna methylation
|
|
US8993341B2
(en)
|
2011-05-12 |
2015-03-31 |
Exact Sciences Corporation |
Removal of PCR inhibitors
|
|
CA2835345C
(en)
*
|
2011-05-12 |
2021-03-09 |
Exact Sciences Corporation |
Isolation of nucleic acids
|
|
WO2013064908A1
(en)
*
|
2011-11-04 |
2013-05-10 |
Oslo Universitetssykehus Hf |
Methods and biomarkers for analysis of colorectal cancer
|
|
EP2788505B1
(en)
|
2011-12-06 |
2017-08-23 |
MDxHealth SA |
Methods of detecting mutations and epigenetic changes
|
|
US9744155B2
(en)
|
2012-03-28 |
2017-08-29 |
Ixcela, Inc. |
IPA as a therapeutic agent, as a protective agent, and as a biomarker of disease risk
|
|
US10233503B2
(en)
|
2012-05-24 |
2019-03-19 |
Fundació Institut D'investigació Biomèdica De Bellvitge (Idibell) |
Method for the identification of the origin of a cancer of unknown primary origin by methylation analysis
|
|
AU2012388616A1
(en)
|
2012-08-31 |
2015-04-02 |
National Defense Medical Center |
Method for screening cancer
|
|
CN102787174B
(zh)
*
|
2012-09-06 |
2013-08-07 |
南京大学 |
胃肠肿瘤发病相关抑癌基因表观突变检测试剂盒及其用途
|
|
AU2013355260B2
(en)
*
|
2012-12-04 |
2019-07-25 |
Caris Mpi, Inc. |
Molecular profiling for cancer
|
|
EP3878977B1
(en)
|
2013-03-14 |
2023-05-03 |
Mayo Foundation for Medical Education and Research |
Detecting neoplasm
|
|
US9644232B2
(en)
*
|
2013-07-26 |
2017-05-09 |
General Electric Company |
Method and device for collection and amplification of circulating nucleic acids
|
|
WO2015066695A1
(en)
*
|
2013-11-04 |
2015-05-07 |
Exact Sciences Corporation |
Multiple-control calibrators for dna quantitation
|
|
EP2886659A1
(en)
*
|
2013-12-20 |
2015-06-24 |
AIT Austrian Institute of Technology GmbH |
Gene methylation based colorectal cancer diagnosis
|
|
JP6830355B2
(ja)
*
|
2014-01-31 |
2021-02-17 |
イクセラ,インコーポレイテッド |
バイオマーカーとしての共有結合した代謝物質
|
|
WO2019161126A1
(en)
|
2018-02-14 |
2019-08-22 |
Dermtech, Inc. |
Novel gene classifiers and uses thereof in non-melanoma skin cancers
|
|
JP2015177745A
(ja)
*
|
2014-03-18 |
2015-10-08 |
愛知県 |
肺癌の検査方法
|
|
WO2015153284A1
(en)
|
2014-03-31 |
2015-10-08 |
Mayo Foundation For Medical Education And Research |
Detecting colorectal neoplasm
|
|
US10184154B2
(en)
|
2014-09-26 |
2019-01-22 |
Mayo Foundation For Medical Education And Research |
Detecting cholangiocarcinoma
|
|
CN104561258B
(zh)
*
|
2014-10-08 |
2016-08-24 |
王红卫 |
一种用于直结肠癌早期诊断的检测试剂盒及其应用
|
|
GB201418965D0
(cg-RX-API-DMAC7.html)
*
|
2014-10-24 |
2014-12-10 |
Ospedale San Raffaele And Fond Telethon |
|
|
US20170322218A1
(en)
|
2014-11-27 |
2017-11-09 |
Public University Corporation Yokohama City University |
Method and reagent for detecting ovarian clear cell adenocarcinoma
|
|
US9984201B2
(en)
|
2015-01-18 |
2018-05-29 |
Youhealth Biotech, Limited |
Method and system for determining cancer status
|
|
US10030272B2
(en)
|
2015-02-27 |
2018-07-24 |
Mayo Foundation For Medical Education And Research |
Detecting gastrointestinal neoplasms
|
|
CN107532124B
(zh)
|
2015-03-27 |
2022-08-09 |
精密科学公司 |
检测食管疾病
|
|
JP2016192909A
(ja)
*
|
2015-03-31 |
2016-11-17 |
シスメックス株式会社 |
胃癌に関する情報の取得方法、ならびに胃癌に関する情報を取得するためのマーカーおよび胃癌検出用キット
|
|
CN114574585A
(zh)
*
|
2015-08-31 |
2022-06-03 |
梅约医药教育及研究基金会 |
检测胃肿瘤
|
|
JP7142569B2
(ja)
|
2015-09-09 |
2022-09-27 |
ドローブリッジ ヘルス,インコーポレイテッド |
サンプルの収集、安定化、および保存のためのシステム、方法およびデバイス
|
|
CN105177163B
(zh)
*
|
2015-10-21 |
2018-04-13 |
山东大学齐鲁医院 |
一种用于宫颈癌早期筛查的试剂盒
|
|
AU2016343937B2
(en)
|
2015-10-30 |
2023-01-19 |
Exact Sciences Corporation |
Multiplex amplification detection assay and isolation and detection of DNA from plasma
|
|
CN109153993B
(zh)
|
2016-04-14 |
2023-02-17 |
梅约医学教育与研究基金会 |
检测胰腺高度异型增生
|
|
US10370726B2
(en)
|
2016-04-14 |
2019-08-06 |
Mayo Foundation For Medical Education And Research |
Detecting colorectal neoplasia
|
|
US10202650B2
(en)
|
2016-05-31 |
2019-02-12 |
Youhealth Biotech, Limited |
Methods for monitoring ELOVL2, KLF14 and PENK gene expression following treatment with vitamin C
|
|
CN106119361B
(zh)
*
|
2016-06-28 |
2020-01-07 |
宁波思锐生物科技有限公司 |
用于胃癌早期诊断及预后评估的ndrg4基因甲基化检测的试剂盒及其应用
|
|
CN106011263B
(zh)
*
|
2016-06-28 |
2020-01-07 |
宁波大学 |
用于检测与胃癌相关的ndrg4基因甲基化程度的试剂盒及其应用
|
|
WO2018009703A1
(en)
|
2016-07-06 |
2018-01-11 |
Youhealth Biotech, Limited |
Breast and ovarian cancer methylation markers and uses thereof
|
|
US12359257B2
(en)
|
2016-07-06 |
2025-07-15 |
Helio Health Inc. |
Liver cancer methylation markers and uses thereof
|
|
EP3481403B1
(en)
|
2016-07-06 |
2022-02-09 |
Youhealth Biotech, Limited |
Solid tumor methylation markers and uses thereof
|
|
EP3481951A4
(en)
|
2016-07-06 |
2020-08-05 |
Youhealth Biotech, Limited |
COLON CANCER SPECIFIC METHYLATION MARKERS AND USES OF THESE MARKERS
|
|
US10093986B2
(en)
|
2016-07-06 |
2018-10-09 |
Youhealth Biotech, Limited |
Leukemia methylation markers and uses thereof
|
|
KR20190045146A
(ko)
*
|
2016-07-08 |
2019-05-02 |
하누마트 엘티디 |
대장암 발증 가능성의 판정 방법
|
|
CN106521006A
(zh)
*
|
2016-12-27 |
2017-03-22 |
刘鹏飞 |
Ndrg4基因甲基化检测用试剂体系和试剂盒及其应用
|
|
CN208808491U
(zh)
|
2017-01-10 |
2019-05-03 |
集联健康有限公司 |
一种用于从受试者收集流体样品的装置
|
|
CN108300783A
(zh)
*
|
2017-01-11 |
2018-07-20 |
上海易毕恩基因科技有限公司 |
用于筛选肠癌和/或胃癌的基因标志物的方法、用该方法筛选的基因标志物及其用途
|
|
EP3574110A4
(en)
|
2017-01-27 |
2021-01-13 |
Exact Sciences Development Company, LLC |
DETECTION OF COLUMN NEOPLASIA BY ANALYSIS OF METHYLATED DNA
|
|
WO2018160576A1
(en)
|
2017-02-28 |
2018-09-07 |
Mayo Foundation For Medical Education And Research |
Detecting prostate cancer
|
|
US10513739B2
(en)
|
2017-03-02 |
2019-12-24 |
Youhealth Oncotech, Limited |
Methylation markers for diagnosing hepatocellular carcinoma and lung cancer
|
|
US11614450B2
(en)
*
|
2017-06-02 |
2023-03-28 |
Peter Dominiek Emiel Maria Verhaert |
Mass spectrometry histochemistry of peptides from formaldehyde-fixed, paraffin-embedded tissue
|
|
CN107177679A
(zh)
*
|
2017-06-07 |
2017-09-19 |
北京呈诺医学科技有限公司 |
一种检测食管鳞癌相关基因tfpi2和hspb2启动子甲基化程度的试剂盒
|
|
WO2018237327A1
(en)
|
2017-06-22 |
2018-12-27 |
Triact Therapeutics, Inc. |
Methods of treating glioblastoma
|
|
IT201700072650A1
(it)
*
|
2017-06-28 |
2018-12-28 |
Univ Degli Studi Cagliari |
Metodo per rilevare e/o per la prognosi di neoplasie del colon-retto
|
|
EP3687501A4
(en)
|
2017-09-29 |
2021-06-23 |
Triact Therapeutics, Inc. |
INIPARIB FORMULATIONS AND THEIR USES
|
|
EP3692164B1
(en)
|
2017-10-06 |
2025-10-15 |
Helio Health Inc. |
Methylation markers for diagnosing cancer
|
|
KR102052089B1
(ko)
*
|
2017-11-22 |
2019-12-05 |
연세대학교 산학협력단 |
유전자의 CpG 메틸화 변화를 이용한 간암의 위험도를 평가하는 방법
|
|
US10975443B2
(en)
|
2017-11-30 |
2021-04-13 |
Mayo Foundation For Medical Education And Research |
Detecting breast cancer
|
|
US10648025B2
(en)
|
2017-12-13 |
2020-05-12 |
Exact Sciences Development Company, Llc |
Multiplex amplification detection assay II
|
|
CN111989407B
(zh)
|
2018-03-13 |
2024-10-29 |
格里尔公司 |
异常的片段检测及分类
|
|
CN108460247B
(zh)
*
|
2018-03-29 |
2022-06-07 |
上海锐翌生物科技有限公司 |
基于kras和ndrg4基因确定结直肠肿瘤细胞的方法和系统
|
|
CN112236520B
(zh)
|
2018-04-02 |
2025-01-24 |
格里尔公司 |
甲基化标记和标靶甲基化探针板
|
|
CN108707667B
(zh)
*
|
2018-06-01 |
2021-10-26 |
安徽达健医学科技有限公司 |
一种用于结直肠癌早期诊断的试剂盒及其使用方法
|
|
CA3136405A1
(en)
*
|
2018-06-01 |
2019-12-05 |
Geneoscopy, Inc. |
Detection method for cancer using rna biomarkers
|
|
CN108796078B
(zh)
*
|
2018-06-05 |
2022-07-26 |
苏州唯善生物科技有限公司 |
一种用于消化道癌诊断、检测或筛查的引物和探针组
|
|
CN108977543B
(zh)
*
|
2018-08-06 |
2021-12-14 |
上海锐翌生物科技有限公司 |
一种基于联合检测sdc2和sfrp2基因甲基化水平的结直肠癌早期诊断试剂
|
|
US11441182B2
(en)
*
|
2018-08-08 |
2022-09-13 |
Virginia Commonwealth University |
Multiplexed and recyclable single-molecule sensors for quantitative analysis of nucleic-acid biomarkers
|
|
CA3111887A1
(en)
|
2018-09-27 |
2020-04-02 |
Grail, Inc. |
Methylation markers and targeted methylation probe panel
|
|
US12404540B2
(en)
|
2018-10-17 |
2025-09-02 |
The University Of Queensland |
Epigenetic biomarker and uses therefor
|
|
EP4369356A3
(en)
|
2018-11-30 |
2024-07-24 |
Caris MPI, Inc. |
Next-generation molecular profiling
|
|
WO2020132572A1
(en)
|
2018-12-21 |
2020-06-25 |
Grail, Inc. |
Source of origin deconvolution based on methylation fragments in cell-free-dna samples
|
|
US11041847B1
(en)
|
2019-01-25 |
2021-06-22 |
Ixcela, Inc. |
Detection and modification of gut microbial population
|
|
JP2022524641A
(ja)
|
2019-03-26 |
2022-05-09 |
ダームテック,インク. |
皮膚癌における新規な遺伝子分類子とその使用
|
|
CN109943638A
(zh)
*
|
2019-05-08 |
2019-06-28 |
湖南百伯基因技术有限公司 |
一种检测ndrg4、sdc2和bmp3基因甲基化的引物探针组合及其应用和试剂盒
|
|
US11396679B2
(en)
|
2019-05-31 |
2022-07-26 |
Universal Diagnostics, S.L. |
Detection of colorectal cancer
|
|
CN110283911A
(zh)
*
|
2019-06-28 |
2019-09-27 |
四川沃文特生物技术有限公司 |
用于粪便样本进行早期结直肠癌基因甲基化检测的引物对和探针及试剂盒
|
|
CN110343764B
(zh)
*
|
2019-07-22 |
2020-05-26 |
武汉艾米森生命科技有限公司 |
检测结直肠癌相关基因甲基化的检测试剂的应用和试剂盒
|
|
US11427874B1
(en)
|
2019-08-26 |
2022-08-30 |
Epi One Inc. |
Methods and systems for detection of prostate cancer by DNA methylation analysis
|
|
AU2020374985A1
(en)
|
2019-10-31 |
2022-05-26 |
Exact Sciences Corporation |
Detecting ovarian cancer
|
|
US11898199B2
(en)
|
2019-11-11 |
2024-02-13 |
Universal Diagnostics, S.A. |
Detection of colorectal cancer and/or advanced adenomas
|
|
CA3163319A1
(en)
|
2019-12-02 |
2021-06-10 |
Caris Mpi, Inc. |
Pan-cancer platinum response predictor
|
|
CN111549129B
(zh)
*
|
2020-03-30 |
2023-08-29 |
宁波美康盛德医学检验所有限公司 |
用于检测胃癌的试剂盒及其应用
|
|
WO2021222828A1
(en)
*
|
2020-04-30 |
2021-11-04 |
Guardant Health, Inc. |
Methods for sequence determination using partitioned nucleic acids
|
|
WO2021228418A1
(en)
|
2020-05-15 |
2021-11-18 |
Universal Diagnostics, S.L. |
Methods and systems for identifying methylation biomarkers
|
|
EP4150121A1
(en)
|
2020-06-30 |
2023-03-22 |
Universal Diagnostics, S.A. |
Systems and methods for detection of multiple cancer types
|
|
CN113278693A
(zh)
*
|
2020-07-29 |
2021-08-20 |
上海吉凯医学检验所有限公司 |
早期结直肠癌和腺瘤的dna甲基化标志物、检测其的方法及其应用
|
|
CN112941162A
(zh)
*
|
2020-12-30 |
2021-06-11 |
昆明理工大学 |
一种dna端粒长度和基因甲基化程度相关性的检测方法
|
|
WO2022192510A1
(en)
*
|
2021-03-10 |
2022-09-15 |
University Of Cincinnati |
Epigenetic quantification using dna hybridization-based single-molecule immunofluorescent imaging
|
|
CN113234821B
(zh)
*
|
2021-04-29 |
2022-09-16 |
北京艾克伦医疗科技有限公司 |
鉴定食管癌状态的方法和试剂盒
|
|
TW202307218A
(zh)
*
|
2021-05-14 |
2023-02-16 |
西班牙商通用診斷公司 |
用於疾病偵測的方法
|
|
TW202311533A
(zh)
*
|
2021-05-14 |
2023-03-16 |
西班牙商通用診斷公司 |
用於疾病偵測的方法
|
|
IL311764A
(en)
|
2021-09-30 |
2024-05-01 |
Tivenix Sa |
A method for diagnosing and predicting progression of neurodegenerative diseases or disorders
|
|
TWI839307B
(zh)
*
|
2023-05-06 |
2024-04-11 |
華聯生物科技股份有限公司 |
利用電腦評估肝癌患者治療後病變進展及預後的方法
|