JP2010514786A5 - - Google Patents
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- Publication number
- JP2010514786A5 JP2010514786A5 JP2009544215A JP2009544215A JP2010514786A5 JP 2010514786 A5 JP2010514786 A5 JP 2010514786A5 JP 2009544215 A JP2009544215 A JP 2009544215A JP 2009544215 A JP2009544215 A JP 2009544215A JP 2010514786 A5 JP2010514786 A5 JP 2010514786A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- aryl
- alkyl
- heteroaryl
- nhr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000217 alkyl group Chemical group 0.000 claims 19
- 150000001875 compounds Chemical class 0.000 claims 19
- 125000005418 aryl aryl group Chemical group 0.000 claims 16
- 229910052801 chlorine Inorganic materials 0.000 claims 16
- 229910052731 fluorine Inorganic materials 0.000 claims 16
- 229910052794 bromium Inorganic materials 0.000 claims 15
- 125000001072 heteroaryl group Chemical group 0.000 claims 14
- 229910052739 hydrogen Inorganic materials 0.000 claims 14
- 238000003384 imaging method Methods 0.000 claims 14
- 125000002877 alkyl aryl group Chemical group 0.000 claims 13
- 125000003118 aryl group Chemical group 0.000 claims 13
- 108020005497 Nuclear hormone receptors Proteins 0.000 claims 12
- 229910052740 iodine Inorganic materials 0.000 claims 10
- 125000005647 linker group Chemical group 0.000 claims 7
- 125000003710 aryl alkyl group Chemical group 0.000 claims 5
- 229910052799 carbon Inorganic materials 0.000 claims 5
- 229910052757 nitrogen Inorganic materials 0.000 claims 5
- 229910052760 oxygen Inorganic materials 0.000 claims 5
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 4
- 239000002872 contrast media Substances 0.000 claims 4
- 125000000524 functional group Chemical group 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- 125000004435 hydrogen atoms Chemical class [H]* 0.000 claims 4
- 125000003545 alkoxy group Chemical group 0.000 claims 3
- 125000003282 alkyl amino group Chemical group 0.000 claims 3
- 125000004104 aryloxy group Chemical group 0.000 claims 3
- 201000002674 obstructive nephropathy Diseases 0.000 claims 3
- 229910052717 sulfur Inorganic materials 0.000 claims 3
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 2
- 125000004429 atoms Chemical group 0.000 claims 2
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- -1 CF 3 Inorganic materials 0.000 claims 1
- 125000004103 aminoalkyl group Chemical group 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 230000030214 innervation Effects 0.000 claims 1
- 101700041618 nhr-4 Proteins 0.000 claims 1
- 101700014033 nhr-5 Proteins 0.000 claims 1
- 101700037472 nhr-6 Proteins 0.000 claims 1
- 125000004001 thioalkyl group Chemical group 0.000 claims 1
- TUHOPGDFPMSKNY-VMDKLMDRSA-N C=C/C=C(\C=C/CCNC(N)=N)/OCCF Chemical compound C=C/C=C(\C=C/CCNC(N)=N)/OCCF TUHOPGDFPMSKNY-VMDKLMDRSA-N 0.000 description 1
- WGEYEADLUCMLOJ-FPLPWBNLSA-N NC(N/C=C(\C=C1)/C#CC(Cl)=C1OCCF)=N Chemical compound NC(N/C=C(\C=C1)/C#CC(Cl)=C1OCCF)=N WGEYEADLUCMLOJ-FPLPWBNLSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87721106P | 2006-12-26 | 2006-12-26 | |
| US60/877,211 | 2006-12-26 | ||
| PCT/US2007/088500 WO2008083056A2 (en) | 2006-12-26 | 2007-12-21 | Ligands for imaging cardiac innervation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014152244A Division JP6021860B2 (ja) | 2006-12-26 | 2014-07-25 | 心臓の神経支配を画像化するためのリガンド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010514786A JP2010514786A (ja) | 2010-05-06 |
| JP2010514786A5 true JP2010514786A5 (zh) | 2011-02-24 |
| JP5656408B2 JP5656408B2 (ja) | 2015-01-21 |
Family
ID=39307501
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009544215A Active JP5656408B2 (ja) | 2006-12-26 | 2007-12-21 | 心臓の神経支配を画像化するためのリガンド |
| JP2014152244A Active JP6021860B2 (ja) | 2006-12-26 | 2014-07-25 | 心臓の神経支配を画像化するためのリガンド |
| JP2016085372A Pending JP2016183164A (ja) | 2006-12-26 | 2016-04-21 | 心臓の神経支配を画像化するためのリガンド |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014152244A Active JP6021860B2 (ja) | 2006-12-26 | 2014-07-25 | 心臓の神経支配を画像化するためのリガンド |
| JP2016085372A Pending JP2016183164A (ja) | 2006-12-26 | 2016-04-21 | 心臓の神経支配を画像化するためのリガンド |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US8491868B2 (zh) |
| EP (5) | EP2474526A3 (zh) |
| JP (3) | JP5656408B2 (zh) |
| KR (4) | KR20170102580A (zh) |
| CN (3) | CN101687780B (zh) |
| AU (1) | AU2007339954B2 (zh) |
| BR (1) | BRPI0722082A8 (zh) |
| CA (2) | CA2984226C (zh) |
| CO (1) | CO6231002A2 (zh) |
| DK (3) | DK2474523T3 (zh) |
| ES (3) | ES2805286T3 (zh) |
| HK (1) | HK1138260A1 (zh) |
| IL (3) | IL199563A (zh) |
| MX (2) | MX2009007018A (zh) |
| PL (1) | PL2114873T3 (zh) |
| PT (1) | PT2114873E (zh) |
| RU (1) | RU2506256C2 (zh) |
| SG (1) | SG177918A1 (zh) |
| TW (2) | TWI618544B (zh) |
| WO (1) | WO2008083056A2 (zh) |
| ZA (1) | ZA200904828B (zh) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
| EP2474526A3 (en) * | 2006-12-26 | 2012-07-25 | Lantheus Medical Imaging, Inc. | Ligands for imaging cardiac innervation |
| CN113058046A (zh) | 2010-02-08 | 2021-07-02 | 兰休斯医疗成像公司 | 用于合成显像剂和其中间体的方法和装置 |
| BR122020018194B1 (pt) * | 2010-05-11 | 2021-07-27 | Lantheus Medical Imaging, Inc. | Composições e métodos de síntese de agentes de imagiologia |
| PT2571503E (pt) | 2010-05-14 | 2015-04-29 | Dana Farber Cancer Inst Inc | Composições e a sua utilização no tratamento de neoplasia, doença inflamatória e outros distúrbios |
| JP6022442B2 (ja) | 2010-05-14 | 2016-11-09 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | 男性用避妊組成物および使用方法 |
| CN103154246B (zh) * | 2010-05-14 | 2015-11-25 | 达那-法伯癌症研究所 | 用于治疗白血病的组合物和方法 |
| AR086113A1 (es) | 2011-04-30 | 2013-11-20 | Abbott Lab | Isoxazolinas como agentes terapeuticos |
| BR112014005286B1 (pt) * | 2011-09-09 | 2022-08-23 | Lantheus Medical Imaging, Inc | Compostos de um primeiro e um segundo agente de imageamento para determinar incompatibilidade de inervação e perfusão na parte do indivíduo |
| ES2725314T3 (es) | 2012-04-10 | 2019-09-23 | Lantheus Medical Imaging Inc | Métodos de síntesis radiofarmacéutica |
| AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| US20150246142A1 (en) | 2012-09-25 | 2015-09-03 | The Regents Of The University Of Michigan | Imaging agents |
| JP6682273B2 (ja) * | 2013-01-24 | 2020-04-15 | タイラートン インターナショナル ホールディングス インコーポレイテッドＴｙｌｅｒｔｏｎ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｈｏｌｄｉｎｇｓ Ｉｎｃ． | 神経細胞イメージング及び治療 |
| US10292588B2 (en) | 2013-01-24 | 2019-05-21 | Tylerton International Holdings Inc. | Body structure imaging |
| EP2967410A4 (en) * | 2013-03-11 | 2016-08-31 | Tylerton Internat Holdings Inc | MODELING THE VEGETABLE NERVOUS SYSTEM AND ASSOCIATED APPLICATIONS |
| RU2016105108A (ru) | 2013-07-25 | 2017-08-30 | Дана-Фарбер Кэнсер Инститьют, Инк. | Ингибиторы факторов транскрипции и их применение |
| CN105744985B (zh) * | 2013-09-08 | 2020-04-07 | 泰勒顿国际公司 | 控制减弱的心区的检测 |
| WO2015070020A2 (en) | 2013-11-08 | 2015-05-14 | Dana-Farber Cancer Institute, Inc. | Combination therapy for cancer using bromodomain and extra-terminal (bet) protein inhibitors |
| US10646183B2 (en) | 2014-01-10 | 2020-05-12 | Tylerton International Inc. | Detection of scar and fibrous cardiac zones |
| KR20160115953A (ko) | 2014-01-31 | 2016-10-06 | 다나-파버 캔서 인스티튜트 인크. | 디아미노피리미딘 벤젠술폰 유도체 및 그의 용도 |
| JP2017504651A (ja) | 2014-01-31 | 2017-02-09 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | ジアゼパン誘導体の使用 |
| MX2016011160A (es) | 2014-02-28 | 2017-04-27 | Tensha Therapeutics Inc | Tratamiento de afecciones asociadas con la hiperinsulinemia. |
| CN105491951B (zh) | 2014-07-30 | 2020-11-20 | 纳维斯国际有限公司 | 配准核医学数据 |
| BR112017002369A2 (pt) | 2014-08-08 | 2017-12-05 | Dana Farber Cancer Inst Inc | derivados de diazepana e usos dos mesmos |
| JP2017525759A (ja) | 2014-08-08 | 2017-09-07 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | ジヒドロプテリジノン誘導体およびその使用 |
| EP3307728A4 (en) | 2015-06-12 | 2019-07-17 | Dana Farber Cancer Institute, Inc. | ASSOCIATION THERAPY USING TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS |
| JP2018526421A (ja) | 2015-09-11 | 2018-09-13 | ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド | シアノチエノトリアゾロジアゼピンおよびこれらの使用 |
| SG10202007099TA (en) | 2015-09-11 | 2020-08-28 | Dana Farber Cancer Inst Inc | Acetamide thienotriazoldiazepines and uses thereof |
| EP3380100A4 (en) | 2015-11-25 | 2019-10-02 | Dana-Farber Cancer Institute, Inc. | BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF |
| CN107892651A (zh) * | 2017-11-29 | 2018-04-10 | 陕西慧康生物科技有限责任公司 | 一种合成dl‑盐酸麻黄碱的方法 |
| CN113260310A (zh) * | 2018-10-15 | 2021-08-13 | 百时美施贵宝公司 | 用于成像lpa1受体的放射性配体 |
| EP3682906A1 (en) | 2019-01-17 | 2020-07-22 | Julius-Maximilians-Universität Würzburg | Compound targeting norepinephrine transporter |
| CN109748825B (zh) * | 2019-02-01 | 2022-02-18 | 原子高科股份有限公司 | 一种18f标记的胍甲基取代苯类似物及其应用 |
Family Cites Families (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6012A (en) * | 1849-01-09 | Lithographing co | ||
| FR1010218A (fr) | 1949-02-10 | 1952-06-09 | American Cyanamid Co | Perfectionnements aux sels de guanidine |
| GB1215255A (en) | 1968-03-13 | 1970-12-09 | Pfizer & Co C | Halophenylalkylguanidine compounds |
| US4094881A (en) * | 1976-03-10 | 1978-06-13 | Smithkline Corporation | Process for preparing triazolethiols |
| US4275074A (en) | 1979-03-09 | 1981-06-23 | Graham J. Dobbie | Catecholamine treatment of ocular hypertension |
| US4270537A (en) | 1979-11-19 | 1981-06-02 | Romaine Richard A | Automatic hypodermic syringe |
| US4258188A (en) * | 1980-02-04 | 1981-03-24 | American Home Products Corporation | 2-(1-Piperazinyl)-cycloheptimidazole derivatives |
| US4622217A (en) * | 1984-04-27 | 1986-11-11 | The Regents Of The University Of Michigan | I-4-amino-3-iodobenzylguanidine as imaging and therapeutic agent |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| CA1283827C (en) | 1986-12-18 | 1991-05-07 | Giorgio Cirelli | Appliance for injection of liquid formulations |
| GB8704027D0 (en) | 1987-02-20 | 1987-03-25 | Owen Mumford Ltd | Syringe needle combination |
| EP0288284A3 (en) * | 1987-04-24 | 1990-07-25 | King Faisal Specialist Hospital And Research Centre | Method of producing iodine 124 and meta-iodobenzylguanidine containing iodine 124 |
| US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
| US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
| US4940460A (en) | 1987-06-19 | 1990-07-10 | Bioject, Inc. | Patient-fillable and non-invasive hypodermic injection device assembly |
| US5339163A (en) | 1988-03-16 | 1994-08-16 | Canon Kabushiki Kaisha | Automatic exposure control device using plural image plane detection areas |
| FR2638359A1 (fr) | 1988-11-03 | 1990-05-04 | Tino Dalto | Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
| US5190521A (en) | 1990-08-22 | 1993-03-02 | Tecnol Medical Products, Inc. | Apparatus and method for raising a skin wheal and anesthetizing skin |
| US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
| GB9118204D0 (en) | 1991-08-23 | 1991-10-09 | Weston Terence E | Needle-less injector |
| SE9102652D0 (sv) | 1991-09-13 | 1991-09-13 | Kabi Pharmacia Ab | Injection needle arrangement |
| US5674863A (en) * | 1991-10-18 | 1997-10-07 | Genentech, Inc. | Nonpeptidyl integrin inhibitors having specificity for the GPIIb IIIa receptor |
| US5328483A (en) | 1992-02-27 | 1994-07-12 | Jacoby Richard M | Intradermal injection device with medication and needle guard |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| US5569189A (en) | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
| US5334144A (en) | 1992-10-30 | 1994-08-02 | Becton, Dickinson And Company | Single use disposable needleless injector |
| TW279864B (zh) * | 1993-02-19 | 1996-07-01 | Janssen Pharmaceutica Nv | |
| US5879657A (en) * | 1993-03-30 | 1999-03-09 | The Dupont Merck Pharmaceutical Company | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
| EP0639573A1 (de) * | 1993-08-03 | 1995-02-22 | Hoechst Aktiengesellschaft | Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament |
| WO1995024176A1 (en) | 1994-03-07 | 1995-09-14 | Bioject, Inc. | Ampule filling device |
| US5466220A (en) | 1994-03-08 | 1995-11-14 | Bioject, Inc. | Drug vial mixing and transfer device |
| US5599302A (en) | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
| US5730723A (en) | 1995-10-10 | 1998-03-24 | Visionary Medical Products Corporation, Inc. | Gas pressured needle-less injection device and method |
| EP0955044B1 (en) | 1995-06-26 | 2005-11-16 | Chelator LLC | Method of inhibiting bacterial or fungal growth using a complexing agent |
| US5893397A (en) | 1996-01-12 | 1999-04-13 | Bioject Inc. | Medication vial/syringe liquid-transfer apparatus |
| GB9607549D0 (en) | 1996-04-11 | 1996-06-12 | Weston Medical Ltd | Spring-powered dispensing device |
| TW499412B (en) | 1996-11-26 | 2002-08-21 | Dimensional Pharm Inc | Aminoguanidines and alkoxyguanidines as protease inhibitors |
| DE69736812T2 (de) | 1996-11-27 | 2007-08-09 | Bristol-Myers Squibb Pharma Co. | Neue integrin rezeptor antagonisten |
| US5993412A (en) | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
| WO1999018053A1 (en) | 1997-10-02 | 1999-04-15 | The University Of Western Ontario | Preparation of radiolabelled haloaromatics via polymer-bound intermediates |
| IT1298087B1 (it) | 1998-01-08 | 1999-12-20 | Fiderm S R L | Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni |
| AU3406599A (en) | 1998-04-09 | 1999-11-01 | Institut Fur Diagnostikforschung Gmbh An Der Freien Universitat Berlin | Novel benzyl guanidine derivatives for therapy and (in-vivo) and (in-vitro) diagnosis |
| WO2000009115A1 (en) | 1998-08-14 | 2000-02-24 | Smithkline Beecham Corporation | Grp receptor ligands |
| US6511648B2 (en) | 1998-12-18 | 2003-01-28 | Bristol-Myers Squibb Pharma Company | Vitronectin receptor antagonist pharmaceuticals |
| US6656448B1 (en) | 2000-02-15 | 2003-12-02 | Bristol-Myers Squibb Pharma Company | Matrix metalloproteinase inhibitors |
| GB0019357D0 (en) | 2000-08-07 | 2000-09-27 | Melacure Therapeutics Ab | Novel phenyl guanidines |
| DE10114561A1 (de) | 2001-03-24 | 2002-09-26 | Wella Ag | Verwendung von Mitteln enthaltend Kreatin, Kreatin und/oder deren Derivaten zur Verstärkung und Strukturverbesserung von keratinischen Fasern |
| US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
| WO2004037166A2 (en) | 2002-09-17 | 2004-05-06 | Isis Pharmaceuticals, Inc. | Therapeutic guanidines |
| US7754188B2 (en) * | 2003-06-30 | 2010-07-13 | Merck Sharp & Dohme Corp. | Radiolabeled cannabinoid-1 receptor modulators |
| EP1691777A4 (en) | 2003-12-01 | 2010-10-13 | Medi Physics Inc | NEW DIFFERENTIAL IMAGING METHOD |
| WO2005095345A2 (en) * | 2004-03-23 | 2005-10-13 | Achillion Pharmaceuticals, Inc. | Heteroaryl guanidines as inhibitors of viral replication |
| CN1950329B (zh) * | 2004-05-28 | 2010-05-05 | 浜松光子学株式会社 | 放射性酪氨酸衍生物、其制造方法、其使用、正电子成像用标识剂和肿瘤的恶性度评价药剂 |
| US20070292354A1 (en) | 2004-09-23 | 2007-12-20 | Guerbet | Contrast Agents Encapsulating Systems for Cest Imaging |
| US20060083681A1 (en) | 2004-10-18 | 2006-04-20 | Ajay Purohit | Compounds for myocardial perfusion imaging |
| US7534418B2 (en) | 2004-12-10 | 2009-05-19 | The Regents Of The University Of Michigan | Imaging agents |
| GB0512770D0 (en) | 2005-06-23 | 2005-07-27 | Hammersmith Imanet Ltd | Imaging compounds |
| ATE509628T1 (de) * | 2006-12-13 | 2011-06-15 | Hoffmann La Roche | Neue 2-imidazole als liganden für trace amine associated receptors (taar) |
| GB0625523D0 (en) | 2006-12-21 | 2007-01-31 | Ge Healthcare Ltd | In vivo imaging agents |
| EP2474526A3 (en) * | 2006-12-26 | 2012-07-25 | Lantheus Medical Imaging, Inc. | Ligands for imaging cardiac innervation |
| WO2008082305A1 (en) | 2006-12-28 | 2008-07-10 | Raufoss Technology As | Control arm |
| WO2008115593A1 (en) | 2007-03-21 | 2008-09-25 | The University Of Montana | 1-[(2'-substituted)-piperazin-1'-yl]-isoquinolines as norepinephrine transporter inhibitor therapeutics and positron emission tomography imaging agents |
| EP2205608B1 (en) | 2007-10-18 | 2013-05-08 | Boehringer Ingelheim International GmbH | Preparation of dihydrothieno[3, 2-d]pyrimidines and intermediates used therein |
| WO2010015340A1 (en) | 2008-08-06 | 2010-02-11 | Bayer Schering Pharma Aktiengesellschaft | Daa-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment |
| GB0906274D0 (en) | 2009-04-09 | 2009-05-20 | Ge Healthcare Ltd | Imaging the central nervous system |
| CN102458396B (zh) | 2009-04-15 | 2017-05-10 | 兰休斯医疗成像公司 | 使用抗坏血酸稳定化放射性药物组合物 |
| CN101555232B (zh) | 2009-05-21 | 2011-01-05 | 北京师范大学 | 氟-18标记哒嗪酮类化合物及制备方法和应用 |
| US8877157B2 (en) | 2009-07-08 | 2014-11-04 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| CN113058046A (zh) | 2010-02-08 | 2021-07-02 | 兰休斯医疗成像公司 | 用于合成显像剂和其中间体的方法和装置 |
| BR122020018194B1 (pt) | 2010-05-11 | 2021-07-27 | Lantheus Medical Imaging, Inc. | Composições e métodos de síntese de agentes de imagiologia |
| BR112014005286B1 (pt) | 2011-09-09 | 2022-08-23 | Lantheus Medical Imaging, Inc | Compostos de um primeiro e um segundo agente de imageamento para determinar incompatibilidade de inervação e perfusão na parte do indivíduo |
| EP2671575A1 (en) | 2012-06-04 | 2013-12-11 | Universität Regensburg | Ras inhibitors |
| JP2017131851A (ja) | 2016-01-29 | 2017-08-03 | 日本特殊陶業株式会社 | マイクロ波加熱用触媒材料、マイクロ波加熱用触媒体、及び、その製造方法 |
-
2007
- 2007-12-21 EP EP12152818A patent/EP2474526A3/en not_active Withdrawn
- 2007-12-21 KR KR1020177024416A patent/KR20170102580A/ko not_active Application Discontinuation
- 2007-12-21 CN CN200780051773.0A patent/CN101687780B/zh active Active
- 2007-12-21 WO PCT/US2007/088500 patent/WO2008083056A2/en active Application Filing
- 2007-12-21 KR KR1020147032350A patent/KR20140140134A/ko not_active Application Discontinuation
- 2007-12-21 EP EP12152815.2A patent/EP2474523B1/en active Active
- 2007-12-21 EP EP12152817.8A patent/EP2474525B1/en active Active
- 2007-12-21 CA CA2984226A patent/CA2984226C/en active Active
- 2007-12-21 MX MX2009007018A patent/MX2009007018A/es active IP Right Grant
- 2007-12-21 ES ES12152817T patent/ES2805286T3/es active Active
- 2007-12-21 SG SG2011095601A patent/SG177918A1/en unknown
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