JP2010511713A5 - - Google Patents
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- JP2010511713A5 JP2010511713A5 JP2009540276A JP2009540276A JP2010511713A5 JP 2010511713 A5 JP2010511713 A5 JP 2010511713A5 JP 2009540276 A JP2009540276 A JP 2009540276A JP 2009540276 A JP2009540276 A JP 2009540276A JP 2010511713 A5 JP2010511713 A5 JP 2010511713A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- drug
- pharmaceutical preparation
- side chain
- cysc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 229920000642 polymer Polymers 0.000 claims 16
- 239000003814 drug Substances 0.000 claims 10
- 229940079593 drug Drugs 0.000 claims 10
- 239000000825 pharmaceutical preparation Substances 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 238000002844 melting Methods 0.000 claims 4
- 230000008018 melting Effects 0.000 claims 4
- 238000010828 elution Methods 0.000 claims 3
- 230000004927 fusion Effects 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 1
- 230000000561 anti-psychotic effect Effects 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 238000001816 cooling Methods 0.000 claims 1
- 239000013078 crystal Substances 0.000 claims 1
- 238000002425 crystallisation Methods 0.000 claims 1
- 230000008025 crystallization Effects 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 229910052698 phosphorus Inorganic materials 0.000 claims 1
- 239000011574 phosphorus Substances 0.000 claims 1
- 229920000058 polyacrylate Polymers 0.000 claims 1
- 229920000515 polycarbonate Polymers 0.000 claims 1
- 239000004417 polycarbonate Substances 0.000 claims 1
- 229920000728 polyester Polymers 0.000 claims 1
- 229920000193 polymethacrylate Polymers 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 239000005266 side chain polymer Substances 0.000 claims 1
- 229910052710 silicon Inorganic materials 0.000 claims 1
- 239000010703 silicon Substances 0.000 claims 1
- 238000007711 solidification Methods 0.000 claims 1
- 230000008023 solidification Effects 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 238000011287 therapeutic dose Methods 0.000 claims 1
- 229920002725 thermoplastic elastomer Polymers 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87323406P | 2006-12-05 | 2006-12-05 | |
| PCT/US2007/024909 WO2008070118A1 (en) | 2006-12-05 | 2007-12-04 | Drug delivery |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010511713A JP2010511713A (ja) | 2010-04-15 |
| JP2010511713A5 true JP2010511713A5 (https=) | 2011-12-08 |
Family
ID=39492556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009540276A Pending JP2010511713A (ja) | 2006-12-05 | 2007-12-04 | 薬物送達 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US8956602B2 (https=) |
| EP (2) | EP2500015A1 (https=) |
| JP (1) | JP2010511713A (https=) |
| AU (1) | AU2007328207A1 (https=) |
| CA (1) | CA2670749A1 (https=) |
| IL (1) | IL198911A0 (https=) |
| WO (2) | WO2008070118A1 (https=) |
Families Citing this family (105)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7858110B2 (en) | 2003-08-11 | 2010-12-28 | Endo Pharmaceuticals Solutions, Inc. | Long term drug delivery devices with polyurethane based polymers and their manufacture |
| CA2437639C (en) | 2003-08-11 | 2016-07-05 | Valera Pharmaceuticals, Inc. | Long term drug delivery devices with polyurethane based polymers and their manufacture |
| MX2008013847A (es) * | 2006-05-11 | 2009-03-04 | Air Prod & Chem | Composiciones para el cuidado personal que contienen polimeros funcionalizados. |
| US20090011017A1 (en) * | 2007-07-05 | 2009-01-08 | Basf Se | Polymers based on water-soluble monoolefinic comprising colloidal silica and their use as matrix polymers for solid dosage forms |
| EP4464384A3 (en) | 2007-08-17 | 2025-01-08 | Purdue Research Foundation | Psma binding ligand-linker conjugates and methods for using |
| US8114883B2 (en) * | 2007-12-04 | 2012-02-14 | Landec Corporation | Polymer formulations for delivery of bioactive materials |
| CA2739181C (en) * | 2008-09-30 | 2017-03-14 | Endo Pharmaceuticals Solutions Inc. | Implantable device for the delivery of risperidone and methods of use thereof |
| WO2010045598A2 (en) * | 2008-10-17 | 2010-04-22 | Purdue Research Foundation | Psma binding ligand-linker conjugates and methods for using |
| WO2010047765A2 (en) * | 2008-10-20 | 2010-04-29 | Massachussetts Institute Of Technology | Nanostructures for drug delivery |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| US8399006B2 (en) | 2009-01-29 | 2013-03-19 | Forsight Vision4, Inc. | Posterior segment drug delivery |
| EP2437735A4 (en) * | 2009-06-04 | 2013-04-03 | Landec Corp | COMPOSITIONS AND METHOD FOR OUTPUT OF MATERIALS |
| US9233063B2 (en) * | 2009-12-17 | 2016-01-12 | Air Products And Chemicals, Inc. | Polymeric compositions for personal care products |
| US10166142B2 (en) | 2010-01-29 | 2019-01-01 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
| WO2011105724A2 (ko) * | 2010-02-24 | 2011-09-01 | 주식회사 티이바이오스 | 관절연골 재생용 지지체 및 이의 제조방법 |
| US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
| US8370120B2 (en) * | 2010-04-30 | 2013-02-05 | Abbott Cardiovascular Systems Inc. | Polymeric stents and method of manufacturing same |
| EP3861969A1 (en) | 2010-08-05 | 2021-08-11 | ForSight Vision4, Inc. | Injector apparatus for drug delivery |
| SI2600812T1 (sl) | 2010-08-05 | 2021-12-31 | ForSight Vision4, Inc., | Naprava za zdravljenje očesa |
| JP6111194B2 (ja) | 2010-08-05 | 2017-04-05 | フォーサイト・ビジョン フォー・インコーポレーテッド | 組み合わせ薬物送達方法および装置 |
| WO2012068549A2 (en) | 2010-11-19 | 2012-05-24 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
| EP4249059B1 (en) | 2011-06-28 | 2025-07-30 | ForSight Vision4, Inc. | An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye |
| WO2013032829A1 (en) * | 2011-08-26 | 2013-03-07 | Arrowhead Research Corporation | Poly(vinyl ester) polymers for in vivo nucleic acid delivery |
| RS61758B1 (sr) | 2011-09-16 | 2021-05-31 | Forsight Vision4 Inc | Aparati za razmenu tečnosti |
| US8546412B2 (en) * | 2011-12-21 | 2013-10-01 | Abbott Cardiovascular Systems, Inc. | Methods of treating heart failure |
| US10010448B2 (en) | 2012-02-03 | 2018-07-03 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| JP2015515530A (ja) | 2012-04-18 | 2015-05-28 | アローヘッド リサーチ コーポレイション | インビボ核酸送達のためのポリ(アクリラート)ポリマー |
| US20140121750A1 (en) * | 2012-10-31 | 2014-05-01 | Cook Medical Technologies Llc | Fixation Process For Nesting Stents |
| BR112015011118B1 (pt) | 2012-11-15 | 2022-12-13 | Endocyte, Inc | Conjugado; composição farmacêutica; e uso de um conjugado |
| CA2905496A1 (en) | 2013-03-14 | 2014-09-25 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
| EP2971010B1 (en) | 2013-03-14 | 2020-06-10 | ModernaTX, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
| ES2972168T3 (es) | 2013-03-28 | 2024-06-11 | Forsight Vision4 Inc | Implante oftálmico para administración de sustancias terapéuticas |
| US20160194368A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Circular polynucleotides |
| US20160194625A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Chimeric polynucleotides |
| JP2016538829A (ja) | 2013-10-03 | 2016-12-15 | モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. | 低密度リポタンパク質受容体をコードするポリヌクレオチド |
| LT4095130T (lt) | 2013-10-18 | 2024-04-25 | Novartis Ag | Žymėti prostatos specifinio membranos antigeno (psma) inhibitoriai, jų naudojimas kaip vizualizavimo medžiagų ir farmacinių medžiagų prostatos vėžiui gydyti |
| BR112016010927A2 (pt) | 2013-11-14 | 2017-08-08 | Endocyte Inc | Conjugado de fórmula |
| CN104744643B (zh) * | 2013-12-25 | 2018-01-12 | 中国石油化工集团公司 | 一种梳型聚合物、制备方法及应用 |
| WO2015119653A1 (en) | 2014-02-04 | 2015-08-13 | Abbott Cardiovascular Systems Inc. | Drug delivery scaffold or stent with a novolimus and lactide based coating such that novolimus has a minimum amount of bonding to the coating |
| EP3169289B1 (en) | 2014-07-15 | 2020-04-15 | ForSight Vision4, Inc. | Ocular implant delivery device |
| EP3169693B1 (en) | 2014-07-16 | 2022-03-09 | ModernaTX, Inc. | Chimeric polynucleotides |
| WO2016014846A1 (en) | 2014-07-23 | 2016-01-28 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of intrabodies |
| BR112017002466A2 (pt) | 2014-08-08 | 2017-12-05 | Forsight Vision4 Inc | formulações estáveis e solúveis de inibidores da tirosina cinase do receptor, e métodos para a sua preparação |
| JP6910949B2 (ja) * | 2014-08-14 | 2021-07-28 | ブラウン ユニバーシティ | タンパク質を安定化させ、送達するための組成物 |
| US10822478B2 (en) * | 2014-10-27 | 2020-11-03 | Borealis Ag | Polymer composition and cable with advantageous electrical properties |
| WO2016077371A1 (en) | 2014-11-10 | 2016-05-19 | Forsight Vision4, Inc. | Expandable drug delivery devices and method of use |
| US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
| AU2016263775A1 (en) * | 2015-05-21 | 2017-12-14 | Isp Investments Llc | Functionally versatile amphiphilic copolymers |
| US20170082625A1 (en) * | 2015-09-17 | 2017-03-23 | University Of Miami | Method and system for microfilter-based capture and release of cancer associated cells |
| JP6777390B2 (ja) * | 2015-10-30 | 2020-10-28 | 株式会社日本触媒 | 生体適合性医療用材料 |
| CA3005238A1 (en) | 2015-11-20 | 2017-05-26 | Forsight Vision4, Inc. | Porous structures for extended release drug delivery devices |
| RS63135B1 (sr) | 2015-12-23 | 2022-05-31 | Modernatx Inc | Postupci upotrebe polinukleotida koji kodiraju ox40 ligand |
| US20190241658A1 (en) | 2016-01-10 | 2019-08-08 | Modernatx, Inc. | Therapeutic mRNAs encoding anti CTLA-4 antibodies |
| JP7009384B2 (ja) | 2016-04-05 | 2022-01-25 | フォーサイト・ビジョン フォー・インコーポレーテッド | 移植可能な眼薬送達デバイス |
| US10773008B2 (en) * | 2016-08-08 | 2020-09-15 | Universiti Brunei Darussalam | Medicated patch for preventing exit site infections during peritoneal dialysis |
| US11458107B2 (en) * | 2016-08-25 | 2022-10-04 | The Regents Of The University Of California | Abiotic anti-VEGF nanoparticle |
| WO2018195560A1 (en) * | 2017-04-12 | 2018-10-25 | Inscent, Inc. | Arthropod pest control compositions, kits and uses thereof |
| JP7158143B2 (ja) * | 2017-04-13 | 2022-10-21 | 株式会社日本触媒 | 生体適合性医療用材料 |
| JP6819435B2 (ja) * | 2017-04-20 | 2021-01-27 | 住友電気工業株式会社 | 樹脂組成物及び電線 |
| US20200171169A1 (en) * | 2017-05-15 | 2020-06-04 | Vanderbilt University | LONG-CIRCULATING ZWITTERIONIC POLYPLEXES FOR siRNA DELIVERY |
| WO2018213789A1 (en) | 2017-05-18 | 2018-11-22 | Modernatx, Inc. | Modified messenger rna comprising functional rna elements |
| JP7285220B2 (ja) | 2017-05-18 | 2023-06-01 | モデルナティエックス インコーポレイテッド | 連結したインターロイキン-12(il12)ポリペプチドをコードするポリヌクレオチドを含む脂質ナノ粒子 |
| EP3638292A1 (en) | 2017-06-14 | 2020-04-22 | ModernaTX, Inc. | Polynucleotides encoding coagulation factor viii |
| CN111132640B (zh) * | 2017-09-25 | 2023-01-10 | 佛罗里达大学研究基金会股份有限公司 | 从含亲水药物的滴眼剂中除去防腐剂 |
| KR20200093581A (ko) | 2017-11-21 | 2020-08-05 | 포사이트 비젼4, 인크. | 확장 가능한 포트 전달 시스템을 위한 유체 교환 기기 및 사용 방법 |
| JP7423521B2 (ja) | 2017-11-22 | 2024-01-29 | モダーナティエックス・インコーポレイテッド | フェニルケトン尿症の治療用のフェニルアラニンヒドロキシラーゼをコードするポリヌクレオチド |
| EP3714048B1 (en) | 2017-11-22 | 2025-04-09 | ModernaTX, Inc. | Polynucleotides encoding ornithine transcarbamylase for the treatment of urea cycle disorders |
| US20220265856A1 (en) | 2017-11-22 | 2022-08-25 | Modernatx, Inc. | Polynucleotides encoding propionyl-coa carboxylase alpha and beta subunits for the treatment of propionic acidemia |
| MA51523A (fr) | 2018-01-05 | 2020-11-11 | Modernatx Inc | Polynucléotides codant pour des anticorps anti-virus du chikungunya |
| US12208102B2 (en) | 2018-04-17 | 2025-01-28 | Endocyte, Inc. | Methods of treating cancer |
| WO2019226650A1 (en) | 2018-05-23 | 2019-11-28 | Modernatx, Inc. | Delivery of dna |
| US20220184185A1 (en) | 2018-07-25 | 2022-06-16 | Modernatx, Inc. | Mrna based enzyme replacement therapy combined with a pharmacological chaperone for the treatment of lysosomal storage disorders |
| WO2020047201A1 (en) | 2018-09-02 | 2020-03-05 | Modernatx, Inc. | Polynucleotides encoding very long-chain acyl-coa dehydrogenase for the treatment of very long-chain acyl-coa dehydrogenase deficiency |
| WO2020056147A2 (en) | 2018-09-13 | 2020-03-19 | Modernatx, Inc. | Polynucleotides encoding glucose-6-phosphatase for the treatment of glycogen storage disease |
| US20220243182A1 (en) | 2018-09-13 | 2022-08-04 | Modernatx, Inc. | Polynucleotides encoding branched-chain alpha-ketoacid dehydrogenase complex e1-alpha, e1-beta, and e2 subunits for the treatment of maple syrup urine disease |
| WO2020056239A1 (en) | 2018-09-14 | 2020-03-19 | Modernatx, Inc. | Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide a1 for the treatment of crigler-najjar syndrome |
| EP3856233A1 (en) | 2018-09-27 | 2021-08-04 | Modernatx, Inc. | Polynucleotides encoding arginase 1 for the treatment of arginase deficiency |
| WO2020206277A1 (en) * | 2019-04-04 | 2020-10-08 | The Regents Of The University Of Colorado, A Body Corporate | Methods and devices for reducing intraocular oxidative damage |
| JP2022532078A (ja) | 2019-05-08 | 2022-07-13 | アストラゼネカ アクチボラグ | 皮膚及び創傷のための組成物並びにその使用の方法 |
| WO2020232474A1 (en) * | 2019-05-15 | 2020-11-19 | The University Of Chicago | Lactate response system and methods |
| CN114096264B (zh) | 2019-05-20 | 2025-03-14 | 因多塞特股份有限公司 | 制备psma缀合物的方法 |
| MX2019014545A (es) * | 2019-12-04 | 2021-06-07 | Univ Mexico Nac Autonoma | Proceso de obtencion de nanoparticulas de polimero para la liberacion de farmacos mediada por receptor. |
| MX2022007389A (es) | 2019-12-19 | 2022-08-10 | Tearclear Corp | Remocion del conservante de las gotas para los ojos. |
| US11674617B2 (en) | 2019-12-27 | 2023-06-13 | Horizon Healthcare LLC | Tube lock |
| US11635148B2 (en) | 2019-12-27 | 2023-04-25 | Horizon Healthcare LLC | Tube clamp |
| US20230235298A1 (en) | 2020-06-01 | 2023-07-27 | Modernatx, Inc. | Phenylalanine hydroxylase variants and uses thereof |
| JP7620825B2 (ja) | 2020-10-28 | 2025-01-24 | パナソニックIpマネジメント株式会社 | 芳香徐放性を有する植物繊維含有複合樹脂成形体 |
| AU2021377895A1 (en) | 2020-11-13 | 2023-06-15 | Modernatx, Inc. | Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis |
| US20240216288A1 (en) | 2021-03-24 | 2024-07-04 | Modernatx, Inc. | Lipid nanoparticles containing polynucleotides encoding propionyl-coa carboxylase alpha and beta subunits and uses thereof |
| WO2022204369A1 (en) | 2021-03-24 | 2022-09-29 | Modernatx, Inc. | Polynucleotides encoding methylmalonyl-coa mutase for the treatment of methylmalonic acidemia |
| US20240207444A1 (en) | 2021-03-24 | 2024-06-27 | Modernatx, Inc. | Lipid nanoparticles containing polynucleotides encoding phenylalanine hydroxylase and uses thereof |
| WO2022204370A1 (en) | 2021-03-24 | 2022-09-29 | Modernatx, Inc. | Lipid nanoparticles and polynucleotides encoding ornithine transcarbamylase for the treatment of ornithine transcarbamylase deficiency |
| WO2022204371A1 (en) | 2021-03-24 | 2022-09-29 | Modernatx, Inc. | Lipid nanoparticles containing polynucleotides encoding glucose-6-phosphatase and uses thereof |
| EP4355882A2 (en) | 2021-06-15 | 2024-04-24 | Modernatx, Inc. | Engineered polynucleotides for cell-type or microenvironment-specific expression |
| WO2022271776A1 (en) | 2021-06-22 | 2022-12-29 | Modernatx, Inc. | Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide a1 for the treatment of crigler-najjar syndrome |
| US20250017867A1 (en) | 2021-10-01 | 2025-01-16 | Modernatx, Inc. | Polynucleotides encoding relaxin for the treatment of fibrosis and/or cardiovascular disease |
| CN114231042B (zh) * | 2021-12-17 | 2022-08-30 | 北京化工大学 | 一种接枝共聚物及其载药组合体与制备方法 |
| WO2023130008A2 (en) * | 2022-01-01 | 2023-07-06 | Sea Pharmaceuticals Llc | Pharmaceutical compositions of 6-(2-(2h-tetrazol-5-yl)ethyl)decahydroisoquinoline-3-carboxylic acid and derivatives thereof |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
| WO2023183909A2 (en) | 2022-03-25 | 2023-09-28 | Modernatx, Inc. | Polynucleotides encoding fanconi anemia, complementation group proteins for the treatment of fanconi anemia |
| US20260035707A1 (en) | 2022-07-26 | 2026-02-05 | Modernatx, Inc. | Engineered polynucleotides for temporal control of expression |
| WO2024197033A1 (en) | 2023-03-21 | 2024-09-26 | Modernatx, Inc. | Polynucleotides encoding relaxin for the treatment of heart failure |
| EP4704816A1 (en) | 2023-05-03 | 2026-03-11 | ModernaTX, Inc. | Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis |
| WO2025072482A1 (en) | 2023-09-27 | 2025-04-03 | Modernatx, Inc. | Immunoglobulin a protease polypeptides, polynucleotides, and uses thereof |
| WO2025255199A1 (en) | 2024-06-05 | 2025-12-11 | Modernatx, Inc. | Argininosuccinate synthase 1 and argininosuccinate lyase polypeptides and polynucleotides and uses thereof |
Family Cites Families (118)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3608549A (en) * | 1970-01-15 | 1971-09-28 | Merrill Edward Wilson | Method of administering drugs and capsule therefor |
| JPS5436828B2 (https=) * | 1974-08-16 | 1979-11-12 | ||
| CA1170070A (en) | 1981-05-01 | 1984-07-03 | Robert J. Quint | Temperature controlled release composition |
| US4558690A (en) * | 1982-01-26 | 1985-12-17 | University Of Scranton | Method of administration of chemotherapy to tumors |
| NL194389C (nl) | 1984-06-14 | 2002-03-04 | Novartis Ag | Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager. |
| GB8417810D0 (en) | 1984-07-12 | 1984-08-15 | Graham N B | Temperature/fluid sensitive devices |
| US4851521A (en) * | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
| JPS6242918A (ja) | 1985-08-20 | 1987-02-24 | Kaken Pharmaceut Co Ltd | 持続性製剤 |
| US4808412A (en) * | 1987-06-11 | 1989-02-28 | Eastman Kodak Company | Rumen-stable compositions |
| US4830855A (en) * | 1987-11-13 | 1989-05-16 | Landec Labs, Inc. | Temperature-controlled active agent dispenser |
| DE3825211A1 (de) * | 1988-07-25 | 1990-02-01 | Henkel Kgaa | Verbesserte koerperresorbierbare knochenwachse (iii) |
| AU5549590A (en) * | 1989-05-11 | 1990-11-29 | Landec Labs, Inc. | Temperature-activated adhesive assemblies |
| US5156911A (en) * | 1989-05-11 | 1992-10-20 | Landec Labs Inc. | Skin-activated temperature-sensitive adhesive assemblies |
| CA1340994C (en) * | 1989-09-21 | 2000-05-16 | Rudolf Edgar Dr. Falk | Treatment of conditions and disease |
| DK469989D0 (da) * | 1989-09-22 | 1989-09-22 | Bukh Meditec | Farmaceutisk praeparat |
| JP2920956B2 (ja) | 1989-10-06 | 1999-07-19 | 藤沢薬品工業株式会社 | ニルバジピン含有持続性錠剤 |
| US5129180A (en) * | 1990-12-07 | 1992-07-14 | Landec Labs, Inc. | Temperature sensitive seed germination control |
| US5120349A (en) * | 1990-12-07 | 1992-06-09 | Landec Labs, Inc. | Microcapsule having temperature-dependent permeability profile |
| US5665822A (en) * | 1991-10-07 | 1997-09-09 | Landec Corporation | Thermoplastic Elastomers |
| US6524274B1 (en) * | 1990-12-28 | 2003-02-25 | Scimed Life Systems, Inc. | Triggered release hydrogel drug delivery system |
| CA2101629A1 (en) * | 1991-02-12 | 1992-08-13 | Edward E. Schmitt | Temperature zone specific pressure-sensitive adhesive compositions, and adhesive assemblies and methods of use associated therewith |
| JPH05194189A (ja) * | 1991-10-23 | 1993-08-03 | Boehringer Ingelheim Kg | 乳酸に基づくオリゴマー及び/又はポリマーの半固形混合物、それらの製造方法並びに吸収性埋め込み物としてのそれらの使用 |
| US5384333A (en) * | 1992-03-17 | 1995-01-24 | University Of Miami | Biodegradable injectable drug delivery polymer |
| US5429654A (en) * | 1992-04-30 | 1995-07-04 | Exxon Research & Engineering Co. | Coated agricultural products |
| IT1260154B (it) * | 1992-07-03 | 1996-03-28 | Lanfranco Callegaro | Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn) |
| US5469867A (en) * | 1992-09-02 | 1995-11-28 | Landec Corporation | Cast-in place thermoplastic channel occluder |
| DK0662097T3 (da) | 1992-09-28 | 2002-09-09 | Metabolix Inc | Polymersammensætning |
| US7083572B2 (en) * | 1993-11-30 | 2006-08-01 | Bristol-Myers Squibb Medical Imaging, Inc. | Therapeutic delivery systems |
| JPH07157424A (ja) * | 1993-12-03 | 1995-06-20 | Lintec Corp | 局所麻酔用ゲル製剤 |
| DE4424267C2 (de) * | 1994-07-09 | 1996-07-11 | Hewlett Packard Gmbh | Vorrichtung zur kontinuierlichen Erfassung von Blutparametern |
| US6004549A (en) | 1994-12-14 | 1999-12-21 | Schering Corporation | Crystalline protein controlled release compositions |
| US6255367B1 (en) * | 1995-03-07 | 2001-07-03 | Landec Corporation | Polymeric modifying agents |
| US6831116B2 (en) * | 1995-03-07 | 2004-12-14 | Landec Corporation | Polymeric modifying agents |
| US5662711A (en) * | 1995-06-07 | 1997-09-02 | Douglas; William | Flow adjustable artery shunt |
| RU2092161C1 (ru) | 1995-06-23 | 1997-10-10 | Санкт-Петербургская Государственная Химико-Фармацевтическая Академия | Средство с регулируемым высвобождением пентоксифиллина |
| GB9514285D0 (en) * | 1995-07-13 | 1995-09-13 | Univ Nottingham | Polymeric lamellar substrate particles for drug delivery |
| US20020114827A1 (en) * | 1995-07-28 | 2002-08-22 | Jie Zhang | Methods and apparatus for improved administration of analgesics |
| DE19545327C2 (de) | 1995-12-05 | 2001-04-19 | Fraunhofer Ges Forschung | Verfahren zur Herstellung von hydrophobierten resorbierbaren Polyestern und deren Verwendung |
| US5792477A (en) * | 1996-05-07 | 1998-08-11 | Alkermes Controlled Therapeutics, Inc. Ii | Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent |
| SE506983C2 (sv) * | 1996-07-02 | 1998-03-09 | Akzo Nobel Nv | Ortoesterbaserad polymer, förfarande för dess framställning och användning därav |
| US6199318B1 (en) * | 1996-12-12 | 2001-03-13 | Landec Corporation | Aqueous emulsions of crystalline polymers for coating seeds |
| US6540984B2 (en) * | 1996-12-12 | 2003-04-01 | Landec Corporation | Aqueous dispersions of crystalline polymers and uses |
| US5852117A (en) * | 1997-08-26 | 1998-12-22 | National Starch And Chemical Investment Holding Corporation | Process for making lactide graft copolymers |
| US6583251B1 (en) * | 1997-09-08 | 2003-06-24 | Emory University | Modular cytomimetic biomaterials, transport studies, preparation and utilization thereof |
| US5895404A (en) * | 1997-09-29 | 1999-04-20 | Ruiz; Carlos E. | Apparatus and methods for percutaneously forming a passageway between adjacent vessels or portions of a vessel |
| US5945457A (en) * | 1997-10-01 | 1999-08-31 | A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science | Process for preparing biologically compatible polymers and their use in medical devices |
| DE19753298A1 (de) * | 1997-12-01 | 1999-06-02 | Basf Ag | Verfahren zur Herstellung von festen Dosierungsformen |
| US5919484A (en) | 1998-01-15 | 1999-07-06 | Isp Investments Inc. | Controlled release, drug-delivery tableted composition including a polymer of a vinyl amide, (meth)acrylic acid, a long chain alkyl (meth)acrylate and a lower alkyl (meth)acrylate |
| CA2324254C (en) | 1998-03-18 | 2005-01-04 | University Technology Corporation | Sustained-release composition including amorphous polymer |
| DE19811919A1 (de) * | 1998-03-18 | 1999-09-23 | Basf Ag | Verwendung von Copolymerisaten monoethylenisch ungesättigter Carbonsäuren als Solubilisatoren |
| WO1999055454A1 (en) * | 1998-04-27 | 1999-11-04 | The Dow Chemical Company | Encapsulated active materials |
| WO1999055396A1 (en) * | 1998-04-27 | 1999-11-04 | Surmodics, Inc. | Bioactive agent release coating |
| US6423345B2 (en) | 1998-04-30 | 2002-07-23 | Acusphere, Inc. | Matrices formed of polymer and hydrophobic compounds for use in drug delivery |
| US6730322B1 (en) * | 1998-04-30 | 2004-05-04 | Acusphere, Inc. | Matrices formed of polymer and hydrophobic compounds for use in drug delivery |
| GB9811059D0 (en) * | 1998-05-23 | 1998-07-22 | Univ Strathclyde | Polyamino acid vesicles |
| US6319521B1 (en) * | 1999-02-10 | 2001-11-20 | University Technology Corporation | Microparticles of lactide-co-glycolide copolymers and methods of making and using the same |
| DE19908753C2 (de) | 1999-02-20 | 2003-10-02 | Jenapharm Gmbh | Bioabbaubare, injizierbare Oligomer-Polymer-Zusammensetzung |
| US6297337B1 (en) * | 1999-05-19 | 2001-10-02 | Pmd Holdings Corp. | Bioadhesive polymer compositions |
| US7169889B1 (en) | 1999-06-19 | 2007-01-30 | Biocon Limited | Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin |
| US6352667B1 (en) * | 1999-08-24 | 2002-03-05 | Absorbable Polymer Technologies, Inc. | Method of making biodegradable polymeric implants |
| US7101928B1 (en) * | 1999-09-17 | 2006-09-05 | Landec Corporation | Polymeric thickeners for oil-containing compositions |
| US6569128B1 (en) * | 1999-09-22 | 2003-05-27 | Advanced Infusion Corporation | Catheter with adjustable flow restrictor |
| US6461631B1 (en) * | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| US6469133B2 (en) * | 1999-12-13 | 2002-10-22 | Board Of Trustees Of Michigan State University | Process for the preparation of polymers of dimeric cyclic esters |
| US20040009229A1 (en) | 2000-01-05 | 2004-01-15 | Unger Evan Charles | Stabilized nanoparticle formulations of camptotheca derivatives |
| CN1419446A (zh) * | 2000-01-27 | 2003-05-21 | 田边制药株式会社 | 缓释制剂及其制法 |
| AU1667701A (en) * | 2000-02-10 | 2001-08-16 | Rohm And Haas Company | Bioadhesive composition |
| DE10018834A1 (de) * | 2000-04-15 | 2001-10-25 | Lohmann Therapie Syst Lts | Transdermale oder transmucosale Darreichungsformen mit einer nicotinhaltigen Wirkstoffkombination zur Raucherentwöhnung |
| KR100452972B1 (ko) | 2000-05-16 | 2004-10-14 | 주식회사 삼양사 | 경피투여용 하이드로젤 조성물 |
| US6679605B2 (en) * | 2000-05-22 | 2004-01-20 | Medennium, Inc. | Crystalline polymeric compositions for ophthalmic devices |
| US20060286064A1 (en) * | 2000-08-30 | 2006-12-21 | Medivas, Llc | Therapeutic polymers and methods |
| US6858634B2 (en) * | 2000-09-15 | 2005-02-22 | Monsanto Technology Llc | Controlled release formulations and methods for their production and use |
| JP2002138033A (ja) * | 2000-10-30 | 2002-05-14 | Shiseido Co Ltd | 抗アクネ用皮膚外用剤 |
| DE60126641T2 (de) * | 2000-11-16 | 2008-02-07 | Biocompatibles Uk Ltd., Farnham | Polymere und polymerisationsverfahren |
| US20020106406A1 (en) | 2000-12-08 | 2002-08-08 | Mchugh Anthony J. | Crystallizable/non-crystallizable polymer composites |
| GB0100761D0 (en) * | 2001-01-11 | 2001-02-21 | Biocompatibles Ltd | Drug delivery from stents |
| US6656385B2 (en) * | 2001-02-21 | 2003-12-02 | The Procter & Gamble Company | Functionalized cubic liquid crystalline phase materials and methods for their preparation and use |
| DE10113302B4 (de) * | 2001-03-19 | 2009-09-24 | Fraunhofer-Gesellschaft für die angewandte Forschung e.V. | Verfahren zur Herstellung von Homo- und Copolyestern der Milchsäure |
| US20020134012A1 (en) * | 2001-03-21 | 2002-09-26 | Monsanto Technology, L.L.C. | Method of controlling the release of agricultural active ingredients from treated plant seeds |
| FR2823450B1 (fr) * | 2001-04-12 | 2004-08-27 | Rhodia Chimie Sa | Suspension obtenue a partir d'une emulsion multiple comprenant un compose hydrophobe solide a temperature ambiante et granules obtenus par sechage de la suspension |
| US7030127B2 (en) * | 2001-06-29 | 2006-04-18 | Ethicon, Inc. | Composition and medical devices utilizing bioabsorbable polymeric waxes |
| US6967234B2 (en) * | 2002-12-18 | 2005-11-22 | Ethicon, Inc. | Alkyd-lactone copolymers for medical applications |
| US6815181B2 (en) * | 2001-07-09 | 2004-11-09 | Applera Corporation | Nucleic acid molecules encoding human secreted hemopexin-related proteins |
| WO2003011226A2 (en) * | 2001-08-01 | 2003-02-13 | Smithkline Beecham Corporation | Products and drug delivery vehicles |
| US8303651B1 (en) * | 2001-09-07 | 2012-11-06 | Advanced Cardiovascular Systems, Inc. | Polymeric coating for reducing the rate of release of a therapeutic substance from a stent |
| US6951642B2 (en) * | 2001-09-28 | 2005-10-04 | 3M Innovative Properties Company | Water-in-oil emulsions with anionic groups, compositions, and methods |
| AU2002337803A1 (en) | 2001-10-03 | 2003-04-14 | Glaxo Group Limited | Sustained release pharmaceutical compositions |
| GB0125216D0 (en) | 2001-10-19 | 2001-12-12 | Univ Strathclyde | Dendrimers for use in targeted delivery |
| US20030082217A1 (en) * | 2001-10-25 | 2003-05-01 | Isabelle Afriat | Use of heat-stabilizing microcapsules to improve the activity or penetration of cosmetic or pharmaceutical active principles |
| WO2003072143A1 (en) * | 2002-02-27 | 2003-09-04 | Pharmain, Ltd. | Compositions for delivery of therapeutics and other materials, and methods of making and using the same |
| US7074426B2 (en) * | 2002-03-27 | 2006-07-11 | Frank Kochinke | Methods and drug delivery systems for the treatment of orofacial diseases |
| US7326426B2 (en) | 2002-03-29 | 2008-02-05 | Ethicon, Inc. | Compositions and medical devices utilizing bioabsorbable liquid polymers |
| US6964778B1 (en) * | 2002-09-06 | 2005-11-15 | Health Research, Inc. | Temperature controlled content release from liposomes |
| US7378479B2 (en) | 2002-09-13 | 2008-05-27 | Lubrizol Advanced Materials, Inc. | Multi-purpose polymers, methods and compositions |
| GB0221942D0 (en) * | 2002-09-20 | 2002-10-30 | Univ Strathclyde | Drug delivery |
| GB0221941D0 (en) * | 2002-09-20 | 2002-10-30 | Univ Strathclyde | Polysoaps |
| US7670627B2 (en) | 2002-12-09 | 2010-03-02 | Salvona Ip Llc | pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients |
| US6866860B2 (en) * | 2002-12-19 | 2005-03-15 | Ethicon, Inc. | Cationic alkyd polyesters for medical applications |
| US20040120981A1 (en) | 2002-12-20 | 2004-06-24 | Aruna Nathan | Crosslinked alkyd polyesters for medical applications |
| US20040254419A1 (en) * | 2003-04-08 | 2004-12-16 | Xingwu Wang | Therapeutic assembly |
| UY28326A1 (es) | 2003-05-22 | 2004-06-30 | Osmotica Argentina S A | Dispositivo de ruptura de liberacion controlada con un pasaje preformado |
| US20050249697A1 (en) * | 2003-09-24 | 2005-11-10 | Uhrich Kathryn E | Compositions and methods for the inhibition of bone growth and resorption |
| MEP23508A (en) * | 2003-10-28 | 2010-06-10 | Noven Pharma | Compositions and methods for comtrolling drug loss and delivery in transdermal drug delivery systems |
| US20050181049A1 (en) | 2003-11-19 | 2005-08-18 | Dong Liang C. | Composition and method for enhancing bioavailability |
| WO2005084639A2 (en) | 2004-03-03 | 2005-09-15 | Spherics, Inc. | Polymeric drug delivery system for hydrophobic drugs |
| WO2006002399A2 (en) * | 2004-06-24 | 2006-01-05 | Surmodics, Inc. | Biodegradable implantable medical devices, methods and systems |
| US20060024361A1 (en) * | 2004-07-28 | 2006-02-02 | Isa Odidi | Disintegrant assisted controlled release technology |
| US20060034891A1 (en) * | 2004-08-12 | 2006-02-16 | Laurie Lawin | Biodegradable controlled release bioactive agent delivery device |
| US9011831B2 (en) | 2004-09-30 | 2015-04-21 | Advanced Cardiovascular Systems, Inc. | Methacrylate copolymers for medical devices |
| NZ563846A (en) | 2005-06-03 | 2010-03-26 | Egalet As | A drug delivery system for delivering active substances dispersed in a dispersion medium |
| US20060292222A1 (en) * | 2005-06-21 | 2006-12-28 | Matthew Jonasse | Drug delivery device having zero or near zero-order release kinetics |
| US20070134310A1 (en) * | 2005-09-23 | 2007-06-14 | Nedberge Diane E | Transdermal risperidone delivery system |
| US7579429B2 (en) * | 2005-12-16 | 2009-08-25 | Board Of Trustees Of Michigan State University | Cyclic alkyl substituted glycolides and polylactides therefrom |
| US20070259584A1 (en) * | 2006-05-04 | 2007-11-08 | Ronald Whitehouse | Biodegradable polymer composites and related methods |
| US20090198183A1 (en) * | 2006-11-03 | 2009-08-06 | Krumme John F | Apparatus and methods for injecting dermal fillers |
| WO2008066657A2 (en) | 2006-11-03 | 2008-06-05 | Aesthetic Sciences Corporation | Compositions, devices and methods for modifying soft tissue |
| US20090124996A1 (en) * | 2006-11-03 | 2009-05-14 | Scott Heneveld | Apparatus and methods for injecting high viscosity dermal fillers |
| WO2009086250A1 (en) * | 2007-12-21 | 2009-07-09 | Aesthetic Sciences Corporation | Self-contained pressurized injection device |
-
2007
- 2007-12-04 US US11/999,415 patent/US8956602B2/en not_active Expired - Fee Related
- 2007-12-04 AU AU2007328207A patent/AU2007328207A1/en not_active Abandoned
- 2007-12-04 JP JP2009540276A patent/JP2010511713A/ja active Pending
- 2007-12-04 US US12/448,033 patent/US20100210792A1/en not_active Abandoned
- 2007-12-04 WO PCT/US2007/024909 patent/WO2008070118A1/en not_active Ceased
- 2007-12-04 EP EP12156847A patent/EP2500015A1/en not_active Withdrawn
- 2007-12-04 CA CA002670749A patent/CA2670749A1/en not_active Abandoned
- 2007-12-04 EP EP07862547A patent/EP2101745A4/en not_active Withdrawn
- 2007-12-05 WO PCT/US2007/025032 patent/WO2008070165A1/en not_active Ceased
-
2008
- 2008-12-03 US US12/746,178 patent/US8524259B2/en not_active Expired - Fee Related
-
2009
- 2009-05-24 IL IL198911A patent/IL198911A0/en unknown
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