JP2012517818A5 - - Google Patents

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Publication number
JP2012517818A5
JP2012517818A5 JP2011550552A JP2011550552A JP2012517818A5 JP 2012517818 A5 JP2012517818 A5 JP 2012517818A5 JP 2011550552 A JP2011550552 A JP 2011550552A JP 2011550552 A JP2011550552 A JP 2011550552A JP 2012517818 A5 JP2012517818 A5 JP 2012517818A5
Authority
JP
Japan
Prior art keywords
variable domain
single variable
tnfr1
seq
dom7h
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011550552A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012517818A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2010/052005 external-priority patent/WO2010094720A2/en
Publication of JP2012517818A publication Critical patent/JP2012517818A/ja
Publication of JP2012517818A5 publication Critical patent/JP2012517818A5/ja
Pending legal-status Critical Current

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JP2011550552A 2009-02-19 2010-02-17 改善された抗tnfr1ポリペプチド、抗体可変ドメインおよびアンタゴニスト Pending JP2012517818A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15374609P 2009-02-19 2009-02-19
US61/153,746 2009-02-19
US24119809P 2009-09-10 2009-09-10
US61/241,198 2009-09-10
PCT/EP2010/052005 WO2010094720A2 (en) 2009-02-19 2010-02-17 Improved anti-tnfr1 polypeptides, antibody variable domains & antagonists

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015151376A Division JP2016007218A (ja) 2009-02-19 2015-07-31 改善された抗tnfr1ポリペプチド、抗体可変ドメインおよびアンタゴニスト

Publications (2)

Publication Number Publication Date
JP2012517818A JP2012517818A (ja) 2012-08-09
JP2012517818A5 true JP2012517818A5 (https=) 2013-03-07

Family

ID=42136168

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011550552A Pending JP2012517818A (ja) 2009-02-19 2010-02-17 改善された抗tnfr1ポリペプチド、抗体可変ドメインおよびアンタゴニスト
JP2015151376A Pending JP2016007218A (ja) 2009-02-19 2015-07-31 改善された抗tnfr1ポリペプチド、抗体可変ドメインおよびアンタゴニスト

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015151376A Pending JP2016007218A (ja) 2009-02-19 2015-07-31 改善された抗tnfr1ポリペプチド、抗体可変ドメインおよびアンタゴニスト

Country Status (14)

Country Link
US (1) US20110301335A1 (https=)
EP (1) EP2398827A2 (https=)
JP (2) JP2012517818A (https=)
KR (1) KR20110119806A (https=)
CN (1) CN102405236A (https=)
AU (1) AU2010215479B2 (https=)
BR (1) BRPI1008014A2 (https=)
CA (1) CA2750477A1 (https=)
EA (1) EA022925B1 (https=)
IL (1) IL214648A0 (https=)
MX (1) MX2011008799A (https=)
SG (1) SG173173A1 (https=)
WO (1) WO2010094720A2 (https=)
ZA (1) ZA201105627B (https=)

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WO2015104322A1 (en) 2014-01-09 2015-07-16 Glaxosmithkline Intellectual Property Development Limited Treatment of inflammatory diseases with non-competitive tnfr1 antagonists
US9815886B2 (en) 2014-10-28 2017-11-14 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
WO2016094309A1 (en) * 2014-12-10 2016-06-16 Myosotis Inhibition of tnf signaling in cancer immunotherapy
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CN107043413A (zh) * 2016-02-05 2017-08-15 华中农业大学 一种肺结核相关的尿液生物标志蛋白及其应用
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
CN113711038B (zh) * 2019-01-31 2024-09-06 积水医疗株式会社 用于生物样品中游离aim的免疫分析方法及用于检测对象中nash的方法
EP3927828A4 (en) 2019-02-21 2023-02-01 Enosi Life Sciences Corp. ANTIBODIES AND ENONOMERS
EP4204094A1 (en) * 2020-08-27 2023-07-05 Enosi Therapeutics Corporation Methods and compositions to treat autoimmune diseases and cancer
WO2022117569A1 (en) 2020-12-02 2022-06-09 Oncurious Nv A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer
WO2025021184A1 (zh) * 2023-07-27 2025-01-30 上海复宏汉霖生物医药有限公司 编码尿酸氧化酶的多核苷酸及其相关组合物和方法
WO2025049818A1 (en) 2023-08-29 2025-03-06 Enosi Therapeutics Corporation Tnfr1 antagonists lacking agonist activity and uses thereof

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BR112012010114A2 (pt) * 2009-10-27 2017-08-08 Glaxo Group Ltd domínio variável único de imunoglobulina, ligante multiespecífico, antagonista, uso do antagonista, método para tratamento e/ou profilaxia de uma condição inflamatória em um paciente, ácido nucleico, vetor, e, célula hospedeira.

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