JP2010509315A5 - - Google Patents
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- JP2010509315A5 JP2010509315A5 JP2009535878A JP2009535878A JP2010509315A5 JP 2010509315 A5 JP2010509315 A5 JP 2010509315A5 JP 2009535878 A JP2009535878 A JP 2009535878A JP 2009535878 A JP2009535878 A JP 2009535878A JP 2010509315 A5 JP2010509315 A5 JP 2010509315A5
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- JP
- Japan
- Prior art keywords
- substituted
- targeting agent
- antibody
- compound according
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 CC(CC(C*)O)NC Chemical compound CC(CC(C*)O)NC 0.000 description 3
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86536006P | 2006-11-10 | 2006-11-10 | |
| US60/865,360 | 2006-11-10 | ||
| US93983007P | 2007-05-23 | 2007-05-23 | |
| US60/939,830 | 2007-05-23 | ||
| US94532907P | 2007-06-20 | 2007-06-20 | |
| US60/945,329 | 2007-06-20 | ||
| PCT/IE2007/000110 WO2008056346A2 (en) | 2006-11-10 | 2007-11-12 | Anti-angiogenic compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011283619A Division JP2012121886A (ja) | 2006-11-10 | 2011-12-26 | 抗血管形成化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010509315A JP2010509315A (ja) | 2010-03-25 |
| JP2010509315A5 true JP2010509315A5 (https=) | 2010-12-16 |
| JP4897050B2 JP4897050B2 (ja) | 2012-03-14 |
Family
ID=39364902
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009535878A Expired - Fee Related JP4897050B2 (ja) | 2006-11-10 | 2007-11-12 | 抗血管形成化合物 |
| JP2011283619A Ceased JP2012121886A (ja) | 2006-11-10 | 2011-12-26 | 抗血管形成化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011283619A Ceased JP2012121886A (ja) | 2006-11-10 | 2011-12-26 | 抗血管形成化合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US8288349B2 (https=) |
| EP (2) | EP2368908A3 (https=) |
| JP (2) | JP4897050B2 (https=) |
| KR (2) | KR20120043028A (https=) |
| CN (1) | CN101611053B (https=) |
| AT (1) | ATE520712T1 (https=) |
| AU (1) | AU2007318912B2 (https=) |
| BR (1) | BRPI0718591A2 (https=) |
| CA (1) | CA2669207A1 (https=) |
| DK (1) | DK2089425T3 (https=) |
| IL (1) | IL198581A (https=) |
| MX (1) | MX2009005045A (https=) |
| MY (1) | MY146985A (https=) |
| NO (1) | NO20092203L (https=) |
| NZ (1) | NZ576751A (https=) |
| PL (1) | PL2089425T3 (https=) |
| PT (1) | PT2089425E (https=) |
| WO (1) | WO2008056346A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2368908A3 (en) * | 2006-11-10 | 2011-10-12 | CovX Technologies Ireland Limited | Anti- angiogenic compounds |
| US20090098130A1 (en) * | 2007-01-05 | 2009-04-16 | Bradshaw Curt W | Glucagon-like protein-1 receptor (glp-1r) agonist compounds |
| US8293714B2 (en) * | 2008-05-05 | 2012-10-23 | Covx Technology Ireland, Ltd. | Anti-angiogenic compounds |
| WO2010036930A1 (en) * | 2008-09-26 | 2010-04-01 | Javad Parvizi | Methods and kits for detecting joint infection |
| RU2012157167A (ru) * | 2010-07-12 | 2014-08-20 | КовЭкс Текнолоджиз Айэлэнд Лимитед | Полифункциональные антительные конъюгаты |
| JP2014500248A (ja) * | 2010-11-05 | 2014-01-09 | コヴェックス・テクノロジーズ・アイルランド・リミテッド | 抗糖尿病化合物 |
| WO2013003606A1 (en) | 2011-06-29 | 2013-01-03 | Amgen Inc. | Predictive biomarker of survival in the treatment of renal cell carcinoma |
| CN104125838B (zh) | 2011-12-20 | 2016-12-14 | 辉瑞公司 | 制备肽缀合物和连接基的改进方法 |
| EP3447071A1 (en) | 2012-01-09 | 2019-02-27 | Pfizer Healthcare Ireland | Mutant antibodies and conjugation thereof |
| JP6219923B2 (ja) | 2012-03-28 | 2017-10-25 | アムジェン インコーポレイテッド | Ｄｒ５受容体アゴニストの組み合わせ |
| SMT201800589T1 (it) | 2013-06-12 | 2019-01-11 | Pharis Biotec Gmbh | Peptidi con attivita' antagoniste contro cxcr4 naturale |
| WO2015014376A1 (en) * | 2013-07-31 | 2015-02-05 | Biontech Ag | Diagnosis and therapy of cancer involving cancer stem cells |
| NZ758049A (en) | 2013-10-15 | 2024-03-22 | Seagen Inc | Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics |
| WO2016209972A1 (en) | 2015-06-26 | 2016-12-29 | Amgen Inc. | Biomarker of survival in the treatment of renal cell carcinoma with a vegfr inhibitor and an ang2 inhibitor |
| KR20180090290A (ko) | 2015-12-04 | 2018-08-10 | 시애틀 지네틱스, 인크. | 사차화 튜불리신 화합물들의 컨쥬게이트들 |
| US11793880B2 (en) | 2015-12-04 | 2023-10-24 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
| CN109843919A (zh) | 2016-03-25 | 2019-06-04 | 西雅图基因公司 | 用于制备聚乙二醇化的药物-接头及其中间体的方法 |
| PE20191716A1 (es) | 2017-02-08 | 2019-12-05 | Bristol Myers Squibb Co | Polipeptidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos |
| KR102648564B1 (ko) | 2017-03-24 | 2024-03-19 | 씨젠 인크. | 글루쿠로니드 약물-링커의 제조 공정 및 그 중간물 |
| AU2018259856B2 (en) | 2017-04-28 | 2025-05-01 | Ajinomoto Co., Inc. | Compound having substance that has affinity for soluble protein, cleavable moiety, and reactive group, or salt thereof |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3719667A (en) | 1970-08-24 | 1973-03-06 | Lilly Co Eli | Epimerization of 6-acylamido and 6-imido penicillin sulfoxide esters |
| US3840556A (en) | 1971-05-28 | 1974-10-08 | Lilly Co Eli | Penicillin conversion by halogen electrophiles and anti-bacterials derived thereby |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US5216132A (en) | 1990-01-12 | 1993-06-01 | Protein Design Labs, Inc. | Soluble t-cell antigen receptor chimeric antigens |
| DK0527798T3 (da) | 1990-04-06 | 1997-12-15 | Jolla Cancer Res Found | Fremgangsmåde og sammensætning til behandling af thrombose |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US6080840A (en) | 1992-01-17 | 2000-06-27 | Slanetz; Alfred E. | Soluble T cell receptors |
| US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| US5981478A (en) | 1993-11-24 | 1999-11-09 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
| US5733757A (en) | 1995-12-15 | 1998-03-31 | The Scripps Research Institute | Aldolase catalytic antibody |
| US5739277A (en) | 1995-04-14 | 1998-04-14 | Genentech Inc. | Altered polypeptides with increased half-life |
| DE19544393A1 (de) | 1995-11-15 | 1997-05-22 | Hoechst Schering Agrevo Gmbh | Synergistische herbizide Mischungen |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| US6326176B1 (en) | 1997-12-18 | 2001-12-04 | The Scripps Research Institute | Aldol condensations by catalytic antibodies |
| JP2003516121A (ja) | 1999-09-27 | 2003-05-13 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 不可逆的に結合するエンジニアリング抗体 |
| US6294374B1 (en) | 1999-10-08 | 2001-09-25 | The Scripps Research Institute | Use of catalytic antibodies for synthesizing epothilone |
| DK1399484T3 (da) | 2001-06-28 | 2010-11-08 | Domantis Ltd | Dobbelt-specifik ligand og anvendelse af denne |
| US20030045477A1 (en) | 2001-07-26 | 2003-03-06 | Fortuna Haviv | Peptides having antiangiogenic activity |
| US7138370B2 (en) | 2001-10-11 | 2006-11-21 | Amgen Inc. | Specific binding agents of human angiopoietin-2 |
| US7205275B2 (en) | 2001-10-11 | 2007-04-17 | Amgen Inc. | Methods of treatment using specific binding agents of human angiopoietin-2 |
| EP1443963B1 (en) * | 2001-10-22 | 2014-05-21 | The Scripps Research Institute | Antibody targeting compounds |
| US6737524B2 (en) * | 2002-03-25 | 2004-05-18 | Paul K. Smith | Activated polyethylene glycol compounds |
| AU2003244817B2 (en) | 2002-06-28 | 2010-08-26 | Domantis Limited | Antigen-binding immunoglobulin single variable domains and dual-specific constructs |
| EP1578801A2 (en) | 2002-12-27 | 2005-09-28 | Domantis Limited | Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand |
| US8143380B2 (en) | 2004-07-08 | 2012-03-27 | Amgen Inc. | Therapeutic peptides |
| WO2006036834A2 (en) | 2004-09-24 | 2006-04-06 | Amgen Inc. | MODIFIED Fc MOLECULES |
| EP2368908A3 (en) * | 2006-11-10 | 2011-10-12 | CovX Technologies Ireland Limited | Anti- angiogenic compounds |
-
2007
- 2007-11-12 EP EP20110170480 patent/EP2368908A3/en not_active Withdrawn
- 2007-11-12 JP JP2009535878A patent/JP4897050B2/ja not_active Expired - Fee Related
- 2007-11-12 KR KR1020127005049A patent/KR20120043028A/ko not_active Ceased
- 2007-11-12 CA CA002669207A patent/CA2669207A1/en not_active Abandoned
- 2007-11-12 NZ NZ576751A patent/NZ576751A/en not_active IP Right Cessation
- 2007-11-12 CN CN200780049649.0A patent/CN101611053B/zh not_active Expired - Fee Related
- 2007-11-12 DK DK07827123.6T patent/DK2089425T3/da active
- 2007-11-12 MX MX2009005045A patent/MX2009005045A/es active IP Right Grant
- 2007-11-12 WO PCT/IE2007/000110 patent/WO2008056346A2/en not_active Ceased
- 2007-11-12 AT AT07827123T patent/ATE520712T1/de active
- 2007-11-12 PL PL07827123T patent/PL2089425T3/pl unknown
- 2007-11-12 PT PT07827123T patent/PT2089425E/pt unknown
- 2007-11-12 MY MYPI20091889A patent/MY146985A/en unknown
- 2007-11-12 BR BRPI0718591-0A patent/BRPI0718591A2/pt not_active IP Right Cessation
- 2007-11-12 KR KR1020097011924A patent/KR101309948B1/ko not_active Expired - Fee Related
- 2007-11-12 EP EP07827123A patent/EP2089425B1/en not_active Not-in-force
- 2007-11-12 AU AU2007318912A patent/AU2007318912B2/en not_active Ceased
- 2007-11-12 US US11/938,766 patent/US8288349B2/en not_active Expired - Fee Related
-
2009
- 2009-05-05 IL IL198581A patent/IL198581A/en active IP Right Grant
- 2009-06-08 NO NO20092203A patent/NO20092203L/no not_active Application Discontinuation
-
2011
- 2011-12-26 JP JP2011283619A patent/JP2012121886A/ja not_active Ceased
-
2012
- 2012-08-13 US US13/584,721 patent/US8912148B2/en not_active Expired - Fee Related
-
2014
- 2014-10-31 US US14/530,444 patent/US20150057431A1/en not_active Abandoned
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