JP2010509315A5 - - Google Patents

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Publication number
JP2010509315A5
JP2010509315A5 JP2009535878A JP2009535878A JP2010509315A5 JP 2010509315 A5 JP2010509315 A5 JP 2010509315A5 JP 2009535878 A JP2009535878 A JP 2009535878A JP 2009535878 A JP2009535878 A JP 2009535878A JP 2010509315 A5 JP2010509315 A5 JP 2010509315A5
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JP
Japan
Prior art keywords
substituted
targeting agent
antibody
compound according
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2009535878A
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English (en)
Japanese (ja)
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JP2010509315A (ja
JP4897050B2 (ja
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Priority claimed from PCT/IE2007/000110 external-priority patent/WO2008056346A2/en
Publication of JP2010509315A publication Critical patent/JP2010509315A/ja
Publication of JP2010509315A5 publication Critical patent/JP2010509315A5/ja
Application granted granted Critical
Publication of JP4897050B2 publication Critical patent/JP4897050B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009535878A 2006-11-10 2007-11-12 抗血管形成化合物 Expired - Fee Related JP4897050B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US86536006P 2006-11-10 2006-11-10
US60/865,360 2006-11-10
US93983007P 2007-05-23 2007-05-23
US60/939,830 2007-05-23
US94532907P 2007-06-20 2007-06-20
US60/945,329 2007-06-20
PCT/IE2007/000110 WO2008056346A2 (en) 2006-11-10 2007-11-12 Anti-angiogenic compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011283619A Division JP2012121886A (ja) 2006-11-10 2011-12-26 抗血管形成化合物

Publications (3)

Publication Number Publication Date
JP2010509315A JP2010509315A (ja) 2010-03-25
JP2010509315A5 true JP2010509315A5 (https=) 2010-12-16
JP4897050B2 JP4897050B2 (ja) 2012-03-14

Family

ID=39364902

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009535878A Expired - Fee Related JP4897050B2 (ja) 2006-11-10 2007-11-12 抗血管形成化合物
JP2011283619A Ceased JP2012121886A (ja) 2006-11-10 2011-12-26 抗血管形成化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011283619A Ceased JP2012121886A (ja) 2006-11-10 2011-12-26 抗血管形成化合物

Country Status (18)

Country Link
US (3) US8288349B2 (https=)
EP (2) EP2089425B1 (https=)
JP (2) JP4897050B2 (https=)
KR (2) KR101309948B1 (https=)
CN (1) CN101611053B (https=)
AT (1) ATE520712T1 (https=)
AU (1) AU2007318912B2 (https=)
BR (1) BRPI0718591A2 (https=)
CA (1) CA2669207A1 (https=)
DK (1) DK2089425T3 (https=)
IL (1) IL198581A (https=)
MX (1) MX2009005045A (https=)
MY (1) MY146985A (https=)
NO (1) NO20092203L (https=)
NZ (1) NZ576751A (https=)
PL (1) PL2089425T3 (https=)
PT (1) PT2089425E (https=)
WO (1) WO2008056346A2 (https=)

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EP2089425B1 (en) * 2006-11-10 2011-08-17 CovX Technologies Ireland Limited Anti-angiogenic compounds
US20090098130A1 (en) * 2007-01-05 2009-04-16 Bradshaw Curt W Glucagon-like protein-1 receptor (glp-1r) agonist compounds
US8293714B2 (en) * 2008-05-05 2012-10-23 Covx Technology Ireland, Ltd. Anti-angiogenic compounds
WO2010036930A1 (en) * 2008-09-26 2010-04-01 Javad Parvizi Methods and kits for detecting joint infection
WO2012007896A1 (en) * 2010-07-12 2012-01-19 Covx Technologies Ireland, Ltd. Multifunctional antibody conjugates
JP2014500248A (ja) * 2010-11-05 2014-01-09 コヴェックス・テクノロジーズ・アイルランド・リミテッド 抗糖尿病化合物
MX358726B (es) 2011-06-29 2018-09-03 Amgen Inc Biomarcador predictivo de supervivencia en el tratamiento de carcinoma de celulas renales.
BR112014015141A2 (pt) 2011-12-20 2020-10-27 Pfizer Inc. processos aperfeiçoados para preparação de conjugados e ligantes de peptídeo
TW201341401A (zh) 2012-01-09 2013-10-16 Covx Technologies Ireland Ltd 突變抗體及其共軛
EP2831116A1 (en) 2012-03-28 2015-02-04 Amgen Inc. Dr5 receptor agonist combinations
ES2699576T3 (es) 2013-06-12 2019-02-11 Pharis Biotec Gmbh Péptidos con actividades antagonistas contra CXCR4 natural
WO2015014376A1 (en) * 2013-07-31 2015-02-05 Biontech Ag Diagnosis and therapy of cancer involving cancer stem cells
ES2826398T3 (es) 2013-10-15 2021-05-18 Seagen Inc Enlazadores-fármacos pegilados para una mejor farmacocinética de los conjugados ligando-fármaco
WO2016209972A1 (en) 2015-06-26 2016-12-29 Amgen Inc. Biomarker of survival in the treatment of renal cell carcinoma with a vegfr inhibitor and an ang2 inhibitor
US11793880B2 (en) 2015-12-04 2023-10-24 Seagen Inc. Conjugates of quaternized tubulysin compounds
CN108367043A (zh) 2015-12-04 2018-08-03 西雅图基因公司 季铵化的微管溶素化合物的缀合物
KR20180134351A (ko) 2016-03-25 2018-12-18 시애틀 지네틱스, 인크. 페길화된 약물-링커 및 그의 중간체의 제조를 위한 공정
CN110637027B (zh) 2017-02-08 2024-08-30 百时美施贵宝公司 包含药代动力学增强子的修饰的松弛素多肽及其用途
AU2018237683A1 (en) 2017-03-24 2019-10-31 Seagen Inc. Process for the preparation of glucuronide drug-linkers and intermediates thereof
EP3617235B1 (en) 2017-04-28 2026-02-18 Ajinomoto Co., Inc. Compound having substance that has affinity for soluble protein, cleavable moiety, and reactive group, or salt thereof

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EP2089425B1 (en) * 2006-11-10 2011-08-17 CovX Technologies Ireland Limited Anti-angiogenic compounds

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