JP4897050B2 - 抗血管形成化合物 - Google Patents
抗血管形成化合物 Download PDFInfo
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- JP4897050B2 JP4897050B2 JP2009535878A JP2009535878A JP4897050B2 JP 4897050 B2 JP4897050 B2 JP 4897050B2 JP 2009535878 A JP2009535878 A JP 2009535878A JP 2009535878 A JP2009535878 A JP 2009535878A JP 4897050 B2 JP4897050 B2 JP 4897050B2
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- antibody
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (7)
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| US86536006P | 2006-11-10 | 2006-11-10 | |
| US60/865,360 | 2006-11-10 | ||
| US93983007P | 2007-05-23 | 2007-05-23 | |
| US60/939,830 | 2007-05-23 | ||
| US94532907P | 2007-06-20 | 2007-06-20 | |
| US60/945,329 | 2007-06-20 | ||
| PCT/IE2007/000110 WO2008056346A2 (en) | 2006-11-10 | 2007-11-12 | Anti-angiogenic compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011283619A Division JP2012121886A (ja) | 2006-11-10 | 2011-12-26 | 抗血管形成化合物 |
Publications (3)
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| JP2010509315A JP2010509315A (ja) | 2010-03-25 |
| JP2010509315A5 JP2010509315A5 (https=) | 2010-12-16 |
| JP4897050B2 true JP4897050B2 (ja) | 2012-03-14 |
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| JP2011283619A Ceased JP2012121886A (ja) | 2006-11-10 | 2011-12-26 | 抗血管形成化合物 |
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| US (3) | US8288349B2 (https=) |
| EP (2) | EP2089425B1 (https=) |
| JP (2) | JP4897050B2 (https=) |
| KR (2) | KR101309948B1 (https=) |
| CN (1) | CN101611053B (https=) |
| AT (1) | ATE520712T1 (https=) |
| AU (1) | AU2007318912B2 (https=) |
| BR (1) | BRPI0718591A2 (https=) |
| CA (1) | CA2669207A1 (https=) |
| DK (1) | DK2089425T3 (https=) |
| IL (1) | IL198581A (https=) |
| MX (1) | MX2009005045A (https=) |
| MY (1) | MY146985A (https=) |
| NO (1) | NO20092203L (https=) |
| NZ (1) | NZ576751A (https=) |
| PL (1) | PL2089425T3 (https=) |
| PT (1) | PT2089425E (https=) |
| WO (1) | WO2008056346A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012121886A (ja) * | 2006-11-10 | 2012-06-28 | Covx Technologies Ireland Ltd | 抗血管形成化合物 |
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| US20090098130A1 (en) * | 2007-01-05 | 2009-04-16 | Bradshaw Curt W | Glucagon-like protein-1 receptor (glp-1r) agonist compounds |
| US8293714B2 (en) * | 2008-05-05 | 2012-10-23 | Covx Technology Ireland, Ltd. | Anti-angiogenic compounds |
| WO2010036930A1 (en) * | 2008-09-26 | 2010-04-01 | Javad Parvizi | Methods and kits for detecting joint infection |
| WO2012007896A1 (en) * | 2010-07-12 | 2012-01-19 | Covx Technologies Ireland, Ltd. | Multifunctional antibody conjugates |
| JP2014500248A (ja) * | 2010-11-05 | 2014-01-09 | コヴェックス・テクノロジーズ・アイルランド・リミテッド | 抗糖尿病化合物 |
| MX358726B (es) | 2011-06-29 | 2018-09-03 | Amgen Inc | Biomarcador predictivo de supervivencia en el tratamiento de carcinoma de celulas renales. |
| BR112014015141A2 (pt) | 2011-12-20 | 2020-10-27 | Pfizer Inc. | processos aperfeiçoados para preparação de conjugados e ligantes de peptídeo |
| TW201341401A (zh) | 2012-01-09 | 2013-10-16 | Covx Technologies Ireland Ltd | 突變抗體及其共軛 |
| EP2831116A1 (en) | 2012-03-28 | 2015-02-04 | Amgen Inc. | Dr5 receptor agonist combinations |
| ES2699576T3 (es) | 2013-06-12 | 2019-02-11 | Pharis Biotec Gmbh | Péptidos con actividades antagonistas contra CXCR4 natural |
| WO2015014376A1 (en) * | 2013-07-31 | 2015-02-05 | Biontech Ag | Diagnosis and therapy of cancer involving cancer stem cells |
| ES2826398T3 (es) | 2013-10-15 | 2021-05-18 | Seagen Inc | Enlazadores-fármacos pegilados para una mejor farmacocinética de los conjugados ligando-fármaco |
| WO2016209972A1 (en) | 2015-06-26 | 2016-12-29 | Amgen Inc. | Biomarker of survival in the treatment of renal cell carcinoma with a vegfr inhibitor and an ang2 inhibitor |
| US11793880B2 (en) | 2015-12-04 | 2023-10-24 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
| CN108367043A (zh) | 2015-12-04 | 2018-08-03 | 西雅图基因公司 | 季铵化的微管溶素化合物的缀合物 |
| KR20180134351A (ko) | 2016-03-25 | 2018-12-18 | 시애틀 지네틱스, 인크. | 페길화된 약물-링커 및 그의 중간체의 제조를 위한 공정 |
| CN110637027B (zh) | 2017-02-08 | 2024-08-30 | 百时美施贵宝公司 | 包含药代动力学增强子的修饰的松弛素多肽及其用途 |
| AU2018237683A1 (en) | 2017-03-24 | 2019-10-31 | Seagen Inc. | Process for the preparation of glucuronide drug-linkers and intermediates thereof |
| EP3617235B1 (en) | 2017-04-28 | 2026-02-18 | Ajinomoto Co., Inc. | Compound having substance that has affinity for soluble protein, cleavable moiety, and reactive group, or salt thereof |
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| WO2006036834A2 (en) * | 2004-09-24 | 2006-04-06 | Amgen Inc. | MODIFIED Fc MOLECULES |
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-
2007
- 2007-11-12 EP EP07827123A patent/EP2089425B1/en not_active Not-in-force
- 2007-11-12 BR BRPI0718591-0A patent/BRPI0718591A2/pt not_active IP Right Cessation
- 2007-11-12 AT AT07827123T patent/ATE520712T1/de active
- 2007-11-12 WO PCT/IE2007/000110 patent/WO2008056346A2/en not_active Ceased
- 2007-11-12 KR KR1020097011924A patent/KR101309948B1/ko not_active Expired - Fee Related
- 2007-11-12 KR KR1020127005049A patent/KR20120043028A/ko not_active Ceased
- 2007-11-12 US US11/938,766 patent/US8288349B2/en not_active Expired - Fee Related
- 2007-11-12 MX MX2009005045A patent/MX2009005045A/es active IP Right Grant
- 2007-11-12 CA CA002669207A patent/CA2669207A1/en not_active Abandoned
- 2007-11-12 DK DK07827123.6T patent/DK2089425T3/da active
- 2007-11-12 AU AU2007318912A patent/AU2007318912B2/en not_active Ceased
- 2007-11-12 PT PT07827123T patent/PT2089425E/pt unknown
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2012
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2014
- 2014-10-31 US US14/530,444 patent/US20150057431A1/en not_active Abandoned
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| JP2005514024A (ja) * | 2001-10-11 | 2005-05-19 | アムジエン・インコーポレーテツド | ヒトアンギオポエチン−２の特異的結合物質 |
| WO2006010057A2 (en) * | 2004-07-08 | 2006-01-26 | Amgen Inc. | Therapeutic peptides |
| WO2006036834A2 (en) * | 2004-09-24 | 2006-04-06 | Amgen Inc. | MODIFIED Fc MOLECULES |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012121886A (ja) * | 2006-11-10 | 2012-06-28 | Covx Technologies Ireland Ltd | 抗血管形成化合物 |
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| US20150057431A1 (en) | 2015-02-26 |
| CN101611053B (zh) | 2015-06-03 |
| NO20092203L (no) | 2009-08-10 |
| US20120301431A1 (en) | 2012-11-29 |
| IL198581A (en) | 2015-10-29 |
| EP2368908A3 (en) | 2011-10-12 |
| WO2008056346B1 (en) | 2008-12-04 |
| AU2007318912B2 (en) | 2011-03-03 |
| AU2007318912A1 (en) | 2008-05-15 |
| EP2368908A2 (en) | 2011-09-28 |
| EP2089425B1 (en) | 2011-08-17 |
| KR101309948B1 (ko) | 2013-09-23 |
| MY146985A (en) | 2012-10-15 |
| ATE520712T1 (de) | 2011-09-15 |
| JP2010509315A (ja) | 2010-03-25 |
| EP2089425A2 (en) | 2009-08-19 |
| WO2008056346A2 (en) | 2008-05-15 |
| JP2012121886A (ja) | 2012-06-28 |
| MX2009005045A (es) | 2009-11-10 |
| PL2089425T3 (pl) | 2012-02-29 |
| BRPI0718591A2 (pt) | 2013-12-03 |
| KR20090090331A (ko) | 2009-08-25 |
| CN101611053A (zh) | 2009-12-23 |
| WO2008056346A3 (en) | 2008-10-23 |
| US8912148B2 (en) | 2014-12-16 |
| US20080166364A1 (en) | 2008-07-10 |
| IL198581A0 (en) | 2011-08-01 |
| KR20120043028A (ko) | 2012-05-03 |
| US8288349B2 (en) | 2012-10-16 |
| CA2669207A1 (en) | 2008-05-15 |
| NZ576751A (en) | 2011-10-28 |
| DK2089425T3 (da) | 2011-10-10 |
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