|
US9453251B2
(en)
|
2002-10-08 |
2016-09-27 |
Pfenex Inc. |
Expression of mammalian proteins in Pseudomonas fluorescens
|
|
AU2005269527B2
(en)
|
2004-07-26 |
2011-12-01 |
Pfenex Inc. |
Process for improved protein expression by strain engineering
|
|
US9512236B2
(en)
|
2006-12-19 |
2016-12-06 |
Ablynx N.V. |
Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
|
|
US9580719B2
(en)
|
2007-04-27 |
2017-02-28 |
Pfenex, Inc. |
Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
|
|
EP2615172A1
(en)
|
2007-04-27 |
2013-07-17 |
Pfenex Inc. |
Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
|
|
CA2706425A1
(en)
|
2007-11-27 |
2009-06-04 |
Ablynx N.V. |
Method for obtaining polypeptide constructs comprising two or more single domain antibodies
|
|
WO2009127691A1
(en)
*
|
2008-04-17 |
2009-10-22 |
Ablynx N.V. |
Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same
|
|
AU2009248049B2
(en)
|
2008-05-16 |
2015-07-23 |
Ablynx N.V. |
Amino acid sequences directed against CXCR4 and other GPCRs and compounds comprising the same
|
|
DK2285408T3
(en)
|
2008-06-05 |
2019-02-04 |
Ablynx Nv |
AMINO ACID SEQUENCES AGAINST COATING PROTEINS IN A VIRUS AND POLYPEPTIDES INCLUDING THESE FOR TREATMENT OF VIRUSAL DISEASES
|
|
US8444976B2
(en)
|
2008-07-02 |
2013-05-21 |
Argen-X B.V. |
Antigen binding polypeptides
|
|
SG174862A1
(en)
|
2009-04-10 |
2011-11-28 |
Ablynx Nv |
Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorder
|
|
US20120134984A1
(en)
*
|
2009-06-01 |
2012-05-31 |
Olga Lubman |
Molecules with extended half-lives and uses thereof
|
|
PT2438087T
(pt)
|
2009-06-05 |
2017-08-04 |
Ablynx Nv |
Construções de nanobody trivalentes de vírus sincicial respiratório humano (hrsv) para a prevenção e/ou tratamento de infeções do trato respiratório
|
|
US9644022B2
(en)
|
2009-11-30 |
2017-05-09 |
Ablynx N.V. |
Amino acid sequences directed against human respiratory syncytial virus (HRSV) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
|
|
WO2011083140A1
(en)
|
2010-01-08 |
2011-07-14 |
Ablynx Nv |
Immunoglobulin single variable domain directed against human cxcr4
|
|
CN102781959A
(zh)
|
2010-02-05 |
2012-11-14 |
埃博灵克斯股份有限公司 |
能够结合血清白蛋白的肽和包含所述肽的化合物、构建体和多肽
|
|
US9120855B2
(en)
|
2010-02-10 |
2015-09-01 |
Novartis Ag |
Biologic compounds directed against death receptor 5
|
|
EP2977055A1
(en)
|
2010-02-16 |
2016-01-27 |
Novo Nordisk A/S |
Factor viii fusion protein
|
|
SG183369A1
(en)
|
2010-03-03 |
2012-09-27 |
Boehringer Ingelheim Int |
Biparatopic abeta binding polypeptides
|
|
EP2552962B1
(en)
|
2010-03-26 |
2016-03-23 |
Ablynx N.V. |
Immunoglobulin single variable domains directed against cxcr7
|
|
CN102971341A
(zh)
|
2010-04-30 |
2013-03-13 |
埃博灵克斯股份有限公司 |
针对异二聚体细胞因子IL-23的p19亚基的纳米抗体的氨基酸序列
|
|
BR112012029588A2
(pt)
|
2010-05-20 |
2017-07-25 |
Ablynx Nv |
materiais biológicas relacionados a her3.
|
|
US11644471B2
(en)
|
2010-09-30 |
2023-05-09 |
Ablynx N.V. |
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
|
|
EP2621953B1
(en)
|
2010-09-30 |
2017-04-05 |
Ablynx N.V. |
Biological materials related to c-met
|
|
JP6181040B2
(ja)
|
2011-03-28 |
2017-08-16 |
アブリンクス エン．ヴェー． |
二特異性抗ｃｘｃｒ７免疫グロブリン単一可変ドメイン
|
|
UA117218C2
(uk)
|
2011-05-05 |
2018-07-10 |
Мерк Патент Гмбх |
Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
|
|
RU2661677C2
(ru)
|
2011-05-27 |
2018-07-18 |
Аблинкс Нв |
Ингибирование резорбции кости с помощью связывающих rank-l пептидов
|
|
EP4350345A3
(en)
|
2011-06-23 |
2024-07-24 |
Ablynx N.V. |
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobin single variable domains
|
|
EP2944653A1
(en)
|
2011-06-23 |
2015-11-18 |
Ablynx N.V. |
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobin single variable domains
|
|
CA2837998C
(en)
*
|
2011-06-23 |
2022-03-01 |
Ablynx Nv |
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
|
|
JP2014525736A
(ja)
|
2011-06-23 |
2014-10-02 |
アブリンクス エン．ヴェー． |
ＩｇＥに対する免疫グロブリン単一可変ドメイン
|
|
WO2013041722A1
(en)
|
2011-09-23 |
2013-03-28 |
Ablynx Nv |
Prolonged inhibition of interleukin-6 mediated signaling
|
|
CN103889451B
(zh)
|
2011-09-30 |
2016-06-29 |
埃博灵克斯股份有限公司 |
与C-Met相关的生物物质
|
|
IL291571B2
(en)
|
2012-02-27 |
2024-08-01 |
Ablynx Nv |
Cx3cr1-binding polypeptides
|
|
NL1040254C2
(en)
|
2013-05-17 |
2014-11-24 |
Ablynx Nv |
Stable formulations of immunoglobulin single variable domains and uses thereof.
|
|
JP6656733B2
(ja)
|
2013-08-05 |
2020-03-04 |
ツイスト バイオサイエンス コーポレーション |
新規合成した遺伝子ライブラリ
|
|
KR20230145503A
(ko)
|
2014-05-16 |
2023-10-17 |
아블린쓰 엔.브이. |
개선된 면역글로불린 가변 도메인
|
|
NL2013661B1
(en)
|
2014-10-21 |
2016-10-05 |
Ablynx Nv |
KV1.3 Binding immunoglobulins.
|
|
DE102014217793A1
(de)
*
|
2014-09-05 |
2016-03-10 |
Jörg Labahn |
Fusionsprotein und Aufreinigungsverfahren
|
|
US10669304B2
(en)
|
2015-02-04 |
2020-06-02 |
Twist Bioscience Corporation |
Methods and devices for de novo oligonucleic acid assembly
|
|
KR101551306B1
(ko)
|
2015-03-23 |
2015-09-09 |
아주대학교산학협력단 |
뉴로필린1 특이적 결합 펩타이드 및 이 펩타이드가 융합된 융합 단백질, 및 이의 용도
|
|
WO2016156570A1
(en)
|
2015-04-02 |
2016-10-06 |
Ablynx N.V. |
Bispecific cxcr4-cd-4 polypeptides with potent anti-hiv activity
|
|
WO2016172377A1
(en)
|
2015-04-21 |
2016-10-27 |
Twist Bioscience Corporation |
Devices and methods for oligonucleic acid library synthesis
|
|
CN107847559B
(zh)
|
2015-05-13 |
2022-07-01 |
埃博灵克斯股份有限公司 |
基于cd3反应性的t细胞募集多肽
|
|
SI3294768T1
(sl)
|
2015-05-13 |
2019-11-29 |
Ablynx Nv |
Polipeptidi, ki rekrutirajo celice T, na osnovi reaktivnosti TCR alfa/beta
|
|
US10844373B2
(en)
|
2015-09-18 |
2020-11-24 |
Twist Bioscience Corporation |
Oligonucleic acid variant libraries and synthesis thereof
|
|
CN108698012A
(zh)
|
2015-09-22 |
2018-10-23 |
特韦斯特生物科学公司 |
用于核酸合成的柔性基底
|
|
NO2768984T3
(enExample)
|
2015-11-12 |
2018-06-09 |
|
|
|
CA3004748C
(en)
|
2015-11-18 |
2021-11-16 |
Merck Sharp & Dohme Corp. |
Pd1 and/or lag3 binders
|
|
MX2018006246A
(es)
|
2015-11-18 |
2018-08-01 |
Merck Sharp & Dohme |
Aglutinantes ctla4p.
|
|
AU2016360987A1
(en)
|
2015-11-27 |
2018-06-07 |
Ablynx Nv |
Polypeptides inhibiting CD40L
|
|
WO2017093478A1
(en)
|
2015-12-04 |
2017-06-08 |
Boehringer Ingelheim International Gmbh |
Biparatopic polypeptides antagonizing wnt signaling in tumor cells
|
|
WO2017202776A1
(en)
|
2016-05-23 |
2017-11-30 |
Luxembourg Institute Of Health (Lih) |
Multifunctional heteromultimeric constructs.
|
|
WO2018007442A1
(en)
|
2016-07-06 |
2018-01-11 |
Ablynx N.V. |
Treatment of il-6r related diseases
|
|
CN106282214A
(zh)
*
|
2016-08-03 |
2017-01-04 |
康众（北京）生物科技有限公司 |
一种快速获得纳米抗体的方法及其应用
|
|
WO2018029182A1
(en)
|
2016-08-08 |
2018-02-15 |
Ablynx N.V. |
Il-6r single variable domain antibodies for treatment of il-6r related diseases
|
|
US11098113B2
(en)
|
2016-09-15 |
2021-08-24 |
Vib Vzw |
Immunoglobulin single variable domains directed against macrophage migration inhibitory factor
|
|
KR102217487B1
(ko)
|
2016-09-21 |
2021-02-23 |
트위스트 바이오사이언스 코포레이션 |
핵산 기반 데이터 저장
|
|
BR112019010061A2
(pt)
|
2016-11-16 |
2019-08-13 |
Ablynx Nv |
polipeptídeos de recrutamento de células t capazes de se ligarem ao cd123 e tcr alfa/beta
|
|
EP4556433A3
(en)
|
2017-02-22 |
2025-08-06 |
Twist Bioscience Corporation |
Nucleic acid based data storage
|
|
BR112019022729A2
(pt)
|
2017-05-31 |
2020-05-19 |
Boehringer Ingelheim Int |
polipeptídeos que antagonizam sinalização da wnt em células de tumor
|
|
AR112069A1
(es)
|
2017-06-02 |
2019-09-18 |
Ablynx Nv |
Inmunoglobulinas que fijan aggrecan
|
|
CN110997001A
(zh)
|
2017-06-02 |
2020-04-10 |
默克专利股份有限公司 |
Mmp13结合免疫球蛋白
|
|
CA3064318A1
(en)
|
2017-06-02 |
2018-12-06 |
Merck Patent Gmbh |
Polypeptides binding adamts5, mmp13 and aggrecan
|
|
KR20250011229A
(ko)
|
2017-06-02 |
2025-01-21 |
메르크 파텐트 게엠베하 |
Adamts 결합성 면역글로불린
|
|
WO2018231864A1
(en)
|
2017-06-12 |
2018-12-20 |
Twist Bioscience Corporation |
Methods for seamless nucleic acid assembly
|
|
KR102784398B1
(ko)
|
2017-06-12 |
2025-03-19 |
트위스트 바이오사이언스 코포레이션 |
심리스 핵산 어셈블리를 위한 방법
|
|
US11407837B2
(en)
|
2017-09-11 |
2022-08-09 |
Twist Bioscience Corporation |
GPCR binding proteins and synthesis thereof
|
|
GB2583590A
(en)
|
2017-10-20 |
2020-11-04 |
Twist Bioscience Corp |
Heated nanowells for polynucleotide synthesis
|
|
KR20250069684A
(ko)
|
2018-01-04 |
2025-05-19 |
트위스트 바이오사이언스 코포레이션 |
Dna 기반 디지털 정보 저장
|
|
JP2021526366A
(ja)
|
2018-05-18 |
2021-10-07 |
ツイスト バイオサイエンス コーポレーション |
核酸ハイブリダイゼーションのためのポリヌクレオチド、試薬、および方法
|
|
GB201818460D0
(en)
*
|
2018-11-13 |
2018-12-26 |
Crescendo Biologics Ltd |
Single domain antibodies that bind human serum albumin
|
|
EP3902816A4
(en)
|
2018-12-26 |
2022-09-14 |
Twist Bioscience Corporation |
HIGHLY ACCURATE POLYNUCLEOTIDE DE NOVO SYNTHESIS
|
|
CN113785057A
(zh)
|
2019-02-26 |
2021-12-10 |
特韦斯特生物科学公司 |
用于抗体优化的变异核酸文库
|
|
EP3930753A4
(en)
|
2019-02-26 |
2023-03-29 |
Twist Bioscience Corporation |
VARIANT NUCLEIC ACID LIBRARIES FOR GLP1 RECEPTOR
|
|
CN109942704B
(zh)
*
|
2019-04-12 |
2023-01-20 |
深圳普瑞金生物药业股份有限公司 |
Hsa单域抗体、核酸及试剂盒
|
|
EP3969473A1
(en)
*
|
2019-05-15 |
2022-03-23 |
Crescendo Biologics Limited |
Binding molecules
|
|
US11332738B2
(en)
|
2019-06-21 |
2022-05-17 |
Twist Bioscience Corporation |
Barcode-based nucleic acid sequence assembly
|
|
US12173282B2
(en)
|
2019-09-23 |
2024-12-24 |
Twist Bioscience, Inc. |
Antibodies that bind CD3 epsilon
|
|
EP4464827A3
(en)
|
2019-09-23 |
2025-02-26 |
Twist Bioscience Corporation |
Variant nucleic acid libraries for crth2
|
|
WO2022178255A2
(en)
|
2021-02-19 |
2022-08-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies that neutralize sars-cov-2
|
|
WO2022204316A2
(en)
|
2021-03-24 |
2022-09-29 |
Twist Bioscience Corporation |
Variant nucleic acid libraries for cd3
|
|
WO2024133935A1
(en)
|
2022-12-23 |
2024-06-27 |
Ablynx Nv |
Protein-based conjugation carriers
|
|
WO2024261235A1
(en)
|
2023-06-22 |
2024-12-26 |
Ablynx Nv |
Chimeric proteins for modulating cytokine receptor activity
|
|
WO2025133253A2
(en)
|
2023-12-22 |
2025-06-26 |
Ablynx Nv |
Protein-based conjugation carriers for intranuclear delivery
|
|
US20250236673A1
(en)
|
2023-12-22 |
2025-07-24 |
Ablynx N.V. |
Protein-based carriers for site-specific amine conjugation
|