JP2010508289A - ケトプロフェン極性誘導体の経皮的送達 - Google Patents

ケトプロフェン極性誘導体の経皮的送達 Download PDF

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Publication number
JP2010508289A
JP2010508289A JP2009534852A JP2009534852A JP2010508289A JP 2010508289 A JP2010508289 A JP 2010508289A JP 2009534852 A JP2009534852 A JP 2009534852A JP 2009534852 A JP2009534852 A JP 2009534852A JP 2010508289 A JP2010508289 A JP 2010508289A
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JP
Japan
Prior art keywords
ketoprofen
composition
derivative
polar
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2009534852A
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English (en)
Japanese (ja)
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JP2010508289A5 (enExample
Inventor
ロッド ハートウィッグ
ディヴィッド ハウズ
Original Assignee
ノーヴェン ファーマシューティカルズ インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by ノーヴェン ファーマシューティカルズ インコーポレイテッド filed Critical ノーヴェン ファーマシューティカルズ インコーポレイテッド
Publication of JP2010508289A publication Critical patent/JP2010508289A/ja
Publication of JP2010508289A5 publication Critical patent/JP2010508289A5/ja
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2009534852A 2006-10-27 2007-10-25 ケトプロフェン極性誘導体の経皮的送達 Abandoned JP2010508289A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85469206P 2006-10-27 2006-10-27
PCT/US2007/082494 WO2008057780A2 (en) 2006-10-27 2007-10-25 Transdermal delivery of ketoprofen polar derivatives

Publications (2)

Publication Number Publication Date
JP2010508289A true JP2010508289A (ja) 2010-03-18
JP2010508289A5 JP2010508289A5 (enExample) 2010-12-09

Family

ID=39365197

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009534852A Abandoned JP2010508289A (ja) 2006-10-27 2007-10-25 ケトプロフェン極性誘導体の経皮的送達

Country Status (8)

Country Link
US (2) US7989496B2 (enExample)
EP (1) EP2089007A2 (enExample)
JP (1) JP2010508289A (enExample)
AU (1) AU2007317629A1 (enExample)
CA (1) CA2667477C (enExample)
MX (1) MX2009004358A (enExample)
NZ (1) NZ576992A (enExample)
WO (1) WO2008057780A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016539997A (ja) * 2013-12-16 2016-12-22 ゾエティス・サービシーズ・エルエルシー 長時間作用型ケトプロフェン組成物

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ602274A (en) 2010-04-30 2014-05-30 Teikoku Pharma Usa Inc Propynylaminoindan transdermal compositions
EP2688561B1 (en) * 2011-03-24 2018-08-22 Teikoku Pharma USA, Inc. Transdermal compositions comprising an active agent layer and an active agent conversion layer
DE102011076869A1 (de) * 2011-06-01 2012-12-06 Beiersdorf Ag Emulsionszubereitungen mit verbesserten rheologischen Eigenschaften
KR20150059177A (ko) 2012-11-02 2015-05-29 테이코쿠 팔마 유에스에이, 인코포레이티드 프로피닐아미노인단 경피 조성물
EP2938335B1 (en) 2012-12-28 2021-03-17 Noven Pharmaceuticals, INC. Multi-polymer compositions for transdermal drug delivery
KR20150103077A (ko) * 2012-12-28 2015-09-09 노벤 파머수티컬즈, 인코퍼레이티드 비스테로이드성 항염증제의 경피 전달을 위한 조성물 및 방법
US9314470B2 (en) 2012-12-28 2016-04-19 Noven Pharmaceuticals, Inc. Transdermal drug delivery systems for levonorgestrel and ethinyl estradiol
WO2014159582A1 (en) 2013-03-14 2014-10-02 Noven Pharmaceuticals, Inc Amphetamine transdermal compositions with acrylic block copolymer
AR095260A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones de anfetaminas transdérmicas estables y métodos de fabricación
AR095259A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria
JP6807848B2 (ja) 2015-02-06 2021-01-06 ノーヴェン ファーマシューティカルズ インコーポレイテッド 経皮薬物送達のための感圧粘着剤
US10406116B2 (en) 2015-02-06 2019-09-10 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
WO2017100103A1 (en) * 2015-12-07 2017-06-15 Cavallino Charles L Compositions and methods of transdermal delivery for therapeutic agents

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5843368B2 (ja) 1980-10-30 1983-09-27 日東電工株式会社 消炎鎮痛貼付剤
US4655767A (en) 1984-10-29 1987-04-07 Dow Corning Corporation Transdermal drug delivery devices with amine-resistant silicone adhesives
US4585836A (en) 1984-10-29 1986-04-29 Dow Corning Corporation Silicone pressure-sensitive adhesive process and product with improved lap-shear stability-II
US4584355A (en) 1984-10-29 1986-04-22 Dow Corning Corporation Silicone pressure-sensitive adhesive process and product with improved lap-shear stability-I
US4591622A (en) 1984-10-29 1986-05-27 Dow Corning Corporation Silicone pressure-sensitive adhesive process and product thereof
US4994267A (en) 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
US5474783A (en) 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5478567A (en) 1991-08-30 1995-12-26 Hisamitsu Pharmaceutical Co., Inc. Antiphlogistic analgesic plaster
CH691209A5 (de) 1993-09-06 2001-05-15 Scherrer Inst Paul Herstellungsverfahren für einen Polmerelektrolyten und elektrochemische Zelle mit diesem Polymerelektrolyten.
KR100228514B1 (ko) * 1996-09-05 1999-11-01 한승수 비스테로이드성 소염진통제를 활성성분으로 하는 경피흡수제제의 제조방법
CA2304958C (en) 1997-09-26 2008-12-30 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
US20030170195A1 (en) 2000-01-10 2003-09-11 Noven Pharmaceuticals, Inc. Compositions and methods for drug delivery
US20050118247A1 (en) * 2000-07-05 2005-06-02 Gunter Cordes Method of making ketoprofen patch delivery system
ITFI20030070A1 (it) * 2003-03-18 2004-09-19 Berlin Chemie Ag Formulazioni topiche stabilizzate contenenti ketoprofene
WO2005009417A1 (en) 2003-07-21 2005-02-03 Noven Pharmaceuticals, Inc. Composition and method for controlling grug delivery from silicone adhesive blends

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016539997A (ja) * 2013-12-16 2016-12-22 ゾエティス・サービシーズ・エルエルシー 長時間作用型ケトプロフェン組成物

Also Published As

Publication number Publication date
NZ576992A (en) 2011-02-25
US7989496B2 (en) 2011-08-02
CA2667477C (en) 2015-12-08
WO2008057780A3 (en) 2009-04-23
AU2007317629A1 (en) 2008-05-15
EP2089007A2 (en) 2009-08-19
US20110263705A1 (en) 2011-10-27
US20090062394A1 (en) 2009-03-05
WO2008057780A2 (en) 2008-05-15
MX2009004358A (es) 2009-06-17
CA2667477A1 (en) 2008-05-15

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