JP2010502629A5 - - Google Patents
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- Publication number
- JP2010502629A5 JP2010502629A5 JP2009526788A JP2009526788A JP2010502629A5 JP 2010502629 A5 JP2010502629 A5 JP 2010502629A5 JP 2009526788 A JP2009526788 A JP 2009526788A JP 2009526788 A JP2009526788 A JP 2009526788A JP 2010502629 A5 JP2010502629 A5 JP 2010502629A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- bolus
- total dose
- human
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010039185 Tenecteplase Proteins 0.000 claims description 20
- 229960000216 tenecteplase Drugs 0.000 claims description 20
- 239000003795 chemical substances by application Substances 0.000 claims description 15
- 208000032382 Ischaemic stroke Diseases 0.000 claims description 12
- 238000001802 infusion Methods 0.000 claims description 8
- 239000003527 fibrinolytic agent Substances 0.000 claims description 5
- 239000004090 neuroprotective agent Substances 0.000 claims description 5
- 229960000103 thrombolytic agent Drugs 0.000 claims description 5
- 101000783577 Dendroaspis angusticeps Thrombostatin Proteins 0.000 claims description 4
- 101000783578 Dendroaspis jamesoni kaimosae Dendroaspin Proteins 0.000 claims description 4
- 239000002319 fibrinogen receptor antagonist Substances 0.000 claims description 4
- 238000001990 intravenous administration Methods 0.000 claims description 2
- 208000006011 Stroke Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 230000000302 ischemic effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 description 18
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 239000005557 antagonist Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82386806P | 2006-08-29 | 2006-08-29 | |
| US60/823,868 | 2006-08-29 | ||
| PCT/US2007/074997 WO2008027687A2 (en) | 2006-08-29 | 2007-08-01 | Use of tenecteplase for treating acute ischemic stroke |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010502629A JP2010502629A (ja) | 2010-01-28 |
| JP2010502629A5 true JP2010502629A5 (enExample) | 2011-08-18 |
| JP5785687B2 JP5785687B2 (ja) | 2015-09-30 |
Family
ID=38835003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009526788A Active JP5785687B2 (ja) | 2006-08-29 | 2007-08-01 | 急性虚血性脳卒中を処置するためのテネクテプラーゼの使用 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20080107641A1 (enExample) |
| EP (1) | EP2056856B1 (enExample) |
| JP (1) | JP5785687B2 (enExample) |
| KR (1) | KR20090045405A (enExample) |
| CN (1) | CN101505785A (enExample) |
| AU (1) | AU2007290277B2 (enExample) |
| BR (1) | BRPI0716143A2 (enExample) |
| CA (1) | CA2661012C (enExample) |
| CO (1) | CO6150188A2 (enExample) |
| EA (1) | EA015573B1 (enExample) |
| EC (1) | ECSP099178A (enExample) |
| IL (2) | IL196987A (enExample) |
| MX (1) | MX2009001918A (enExample) |
| MY (1) | MY163119A (enExample) |
| NO (1) | NO342302B1 (enExample) |
| NZ (1) | NZ574767A (enExample) |
| SG (3) | SG10201501498VA (enExample) |
| TW (1) | TWI439282B (enExample) |
| UA (1) | UA97486C2 (enExample) |
| WO (1) | WO2008027687A2 (enExample) |
| ZA (1) | ZA200900957B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7759506B2 (en) | 2002-02-25 | 2010-07-20 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
| US8030350B2 (en) | 2005-02-24 | 2011-10-04 | Diffusion Pharmaceuticals Llc | Trans carotenoids, their synthesis, formulation and uses |
| TWI439282B (zh) | 2006-08-29 | 2014-06-01 | Genentech Inc | 以血栓溶解劑治療中風之方法 |
| MX2009010988A (es) | 2007-04-13 | 2010-03-15 | Diffusion Pharmaceuticals Llc | Uso de trans-carotenoides bipolares como un tratamiento previo y en el tratamiento de una enfermedad vascular periferica. |
| US9034007B2 (en) | 2007-09-21 | 2015-05-19 | Insera Therapeutics, Inc. | Distal embolic protection devices with a variable thickness microguidewire and methods for their use |
| JP2012513812A (ja) * | 2008-12-24 | 2012-06-21 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Ｍｒ卒中検出および処置による心臓介入のシステム、方法および装置 |
| EP2445339B1 (en) | 2009-06-22 | 2019-08-07 | Diffusion Pharmaceuticals LLC | Diffusion enhancing compound and its use with a thrombolytic |
| JP5762414B2 (ja) * | 2009-08-24 | 2015-08-12 | ハフ イヤ インスティテュート | 急性音響外傷の治療方法 |
| ES2654945T3 (es) | 2010-06-02 | 2018-02-15 | Diffusion Pharmaceuticals Llc | Formulaciones orales de carotenoides trans bipolares |
| MY171723A (en) * | 2010-12-23 | 2019-10-24 | Gennova Biopharmaceuticals Ltd | Pharmaceutical compositions of tenecteplase |
| WO2014062888A1 (en) | 2012-10-18 | 2014-04-24 | University Of South Florida | Compositions and methods for treating stroke |
| US8715315B1 (en) | 2013-03-15 | 2014-05-06 | Insera Therapeutics, Inc. | Vascular treatment systems |
| US8679150B1 (en) | 2013-03-15 | 2014-03-25 | Insera Therapeutics, Inc. | Shape-set textile structure based mechanical thrombectomy methods |
| JP6437517B2 (ja) | 2013-03-15 | 2018-12-12 | インセラ セラピューティクス，インク． | 血管治療装置及び方法 |
| US8715314B1 (en) | 2013-03-15 | 2014-05-06 | Insera Therapeutics, Inc. | Vascular treatment measurement methods |
| US10220008B2 (en) | 2013-08-14 | 2019-03-05 | Stc.Unm | Treatment and prevention of stroke and other neurological disorders |
| MX383595B (es) * | 2014-10-21 | 2025-03-14 | Gennova Biopharmaceuticals Ltd | Proceso novedoso de purificacion para el aislamiento y produccion comercial de tnk-tpa recombinante (tenecteplasa) |
| CN108697423A (zh) | 2016-02-16 | 2018-10-23 | 伊瑟拉医疗公司 | 抽吸装置和锚定的分流装置 |
| WO2017165667A1 (en) | 2016-03-24 | 2017-09-28 | Diffusion Pharmaceuticals Llc | Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer |
| EP3573635B1 (en) * | 2017-01-24 | 2021-05-12 | Ekos Corporation | Method for the treatment of thromboembolism |
| EP3624832B1 (en) * | 2017-05-16 | 2025-08-20 | Institut National de la Santé et de la Recherche Médicale | Methods and pharmaceutical compositions for the treatment of acute ischemic stroke |
| US10426424B2 (en) | 2017-11-21 | 2019-10-01 | General Electric Company | System and method for generating and performing imaging protocol simulations |
| WO2021158799A1 (en) * | 2020-02-04 | 2021-08-12 | The Regents Of The University Of Colorado, A Body Corporate | Prophylactic uses of annexin a2 |
| MX2022010160A (es) * | 2020-02-19 | 2022-10-10 | Nono Inc | Tratamiento de combinación de apoplejia con inhibidor de psd-95 escindible por plasmina y reperfusión. |
| CN114984197A (zh) * | 2022-07-01 | 2022-09-02 | 江苏丰华生物制药有限公司 | 替奈普酶在制备用于治疗急性缺血性卒中的药物组合物中的应用 |
| CN115487294A (zh) * | 2022-07-12 | 2022-12-20 | 上海丰华天力通生物医药有限公司 | 替奈普酶在制备用于治疗轻型缺血性卒中的药物组合物中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| EP0786257B1 (en) | 1992-06-03 | 2003-07-30 | Genentech, Inc. | Tissue plasminogen activator glycosylation variants with improved therapeutic properties |
| JP2002173447A (ja) * | 2000-09-29 | 2002-06-21 | Yamanouchi Pharmaceut Co Ltd | 脳塞栓症治療用医薬組成物 |
| US7084118B2 (en) * | 2002-02-22 | 2006-08-01 | Genentech, Inc. | Combination treatment with t-PA variant and low molecular weight heparin |
| US20030180282A1 (en) * | 2002-03-25 | 2003-09-25 | Victor Serebruany | Method of treatment of thrombotic events |
| US20070014779A1 (en) * | 2002-11-14 | 2007-01-18 | Genentech, Inc. | Plasminogen activator variant formulations |
| WO2006094120A2 (en) * | 2005-03-02 | 2006-09-08 | The Regents Of The University Of California | Treatment for embolic stroke |
| TWI439282B (zh) | 2006-08-29 | 2014-06-01 | Genentech Inc | 以血栓溶解劑治療中風之方法 |
-
2007
- 2007-08-01 TW TW096128284A patent/TWI439282B/zh active
- 2007-08-01 AU AU2007290277A patent/AU2007290277B2/en active Active
- 2007-08-01 ZA ZA200900957A patent/ZA200900957B/xx unknown
- 2007-08-01 WO PCT/US2007/074997 patent/WO2008027687A2/en not_active Ceased
- 2007-08-01 CA CA2661012A patent/CA2661012C/en not_active Expired - Fee Related
- 2007-08-01 MY MYPI20090793A patent/MY163119A/en unknown
- 2007-08-01 CN CNA2007800318116A patent/CN101505785A/zh active Pending
- 2007-08-01 EP EP07840638.6A patent/EP2056856B1/en active Active
- 2007-08-01 EA EA200970237A patent/EA015573B1/ru unknown
- 2007-08-01 JP JP2009526788A patent/JP5785687B2/ja active Active
- 2007-08-01 UA UAA200902855A patent/UA97486C2/ru unknown
- 2007-08-01 SG SG10201501498VA patent/SG10201501498VA/en unknown
- 2007-08-01 US US11/832,291 patent/US20080107641A1/en not_active Abandoned
- 2007-08-01 MX MX2009001918A patent/MX2009001918A/es active IP Right Grant
- 2007-08-01 NZ NZ574767A patent/NZ574767A/en unknown
- 2007-08-01 BR BRPI0716143-3A patent/BRPI0716143A2/pt not_active Application Discontinuation
- 2007-08-01 SG SG10201804944XA patent/SG10201804944XA/en unknown
- 2007-08-01 KR KR1020097006363A patent/KR20090045405A/ko not_active Ceased
- 2007-08-01 SG SG2011062213A patent/SG174753A1/en unknown
-
2009
- 2009-02-09 IL IL196987A patent/IL196987A/en active IP Right Grant
- 2009-02-27 CO CO09020350A patent/CO6150188A2/es unknown
- 2009-03-12 EC EC2009009178A patent/ECSP099178A/es unknown
- 2009-03-27 NO NO20091296A patent/NO342302B1/no unknown
-
2011
- 2011-07-22 US US13/189,413 patent/US9023346B2/en active Active
-
2016
- 2016-10-05 IL IL248176A patent/IL248176A0/en unknown
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