JP2019508433A5 - - Google Patents
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- Publication number
- JP2019508433A5 JP2019508433A5 JP2018546036A JP2018546036A JP2019508433A5 JP 2019508433 A5 JP2019508433 A5 JP 2019508433A5 JP 2018546036 A JP2018546036 A JP 2018546036A JP 2018546036 A JP2018546036 A JP 2018546036A JP 2019508433 A5 JP2019508433 A5 JP 2019508433A5
- Authority
- JP
- Japan
- Prior art keywords
- liv
- adc
- subject
- pharmaceutical composition
- drug conjugate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022006944A JP2022058676A (ja) | 2016-03-15 | 2022-01-20 | Ｌｉｖ１－ａｄｃ及び化学療法剤を用いた併用療法 |
| JP2024039750A JP2024075639A (ja) | 2016-03-15 | 2024-03-14 | Ｌｉｖ１－ａｄｃ及び化学療法剤を用いた併用療法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662308639P | 2016-03-15 | 2016-03-15 | |
| US62/308,639 | 2016-03-15 | ||
| US201662317792P | 2016-04-04 | 2016-04-04 | |
| US62/317,792 | 2016-04-04 | ||
| US201662367510P | 2016-07-27 | 2016-07-27 | |
| US62/367,510 | 2016-07-27 | ||
| PCT/US2017/022541 WO2017161007A1 (en) | 2016-03-15 | 2017-03-15 | Combination therapy using a liv1-adc and a chemotherapeutic |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022006944A Division JP2022058676A (ja) | 2016-03-15 | 2022-01-20 | Ｌｉｖ１－ａｄｃ及び化学療法剤を用いた併用療法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019508433A JP2019508433A (ja) | 2019-03-28 |
| JP2019508433A5 true JP2019508433A5 (enExample) | 2020-04-23 |
Family
ID=59852409
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018546036A Pending JP2019508433A (ja) | 2016-03-15 | 2017-03-15 | Ｌｉｖ１−ａｄｃ及び化学療法剤を用いた併用療法 |
| JP2022006944A Pending JP2022058676A (ja) | 2016-03-15 | 2022-01-20 | Ｌｉｖ１－ａｄｃ及び化学療法剤を用いた併用療法 |
| JP2024039750A Pending JP2024075639A (ja) | 2016-03-15 | 2024-03-14 | Ｌｉｖ１－ａｄｃ及び化学療法剤を用いた併用療法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022006944A Pending JP2022058676A (ja) | 2016-03-15 | 2022-01-20 | Ｌｉｖ１－ａｄｃ及び化学療法剤を用いた併用療法 |
| JP2024039750A Pending JP2024075639A (ja) | 2016-03-15 | 2024-03-14 | Ｌｉｖ１－ａｄｃ及び化学療法剤を用いた併用療法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11325980B2 (enExample) |
| EP (1) | EP3429626A4 (enExample) |
| JP (3) | JP2019508433A (enExample) |
| KR (3) | KR20220157515A (enExample) |
| CN (1) | CN108697801A (enExample) |
| AU (2) | AU2017235545A1 (enExample) |
| BR (1) | BR112018068129A2 (enExample) |
| CA (1) | CA3016485A1 (enExample) |
| EA (1) | EA201891968A1 (enExample) |
| IL (1) | IL261505A (enExample) |
| MA (1) | MA45324A (enExample) |
| MX (2) | MX2018010847A (enExample) |
| SG (2) | SG10201912908QA (enExample) |
| WO (1) | WO2017161007A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3786185A1 (en) | 2010-12-06 | 2021-03-03 | Seagen Inc. | Humanized antibodies to liv-1 and use of same to treat cancer |
| MX2020005640A (es) * | 2017-12-01 | 2020-08-20 | Seattle Genetics Inc | Anticuerpos anti-liv1 humanizados para el tratamiento de cancer de mama. |
| WO2020095249A1 (en) * | 2018-11-07 | 2020-05-14 | Crispr Therapeutics Ag | Anti-liv1 immune cell cancer therapy |
| WO2021119105A1 (en) | 2019-12-09 | 2021-06-17 | Seagen Inc. | Combination therapy with liv1-adc and pd-1 antagonist |
| MX2023003404A (es) * | 2020-09-28 | 2023-03-31 | Seagen Inc | Anticuerpos anti-l1vi humanizados para el tratamiento del cancer. |
| CA3213636A1 (en) | 2021-03-18 | 2022-09-22 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| CN120858117A (zh) * | 2023-03-15 | 2025-10-28 | 浙江博锐生物制药有限公司 | 抗liv-1抗体和抗liv-1抗体药物偶联物及其药物用途 |
| WO2025162207A1 (zh) * | 2024-01-31 | 2025-08-07 | 上海复宏汉霖生物技术股份有限公司 | 抗liv1抗体及使用方法 |
| WO2026057076A1 (zh) * | 2024-09-14 | 2026-03-19 | 杭州博之锐生物制药有限公司 | 基于抗liv-1抗体-药物偶联物的耐药癌症的治疗 |
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| FI102355B1 (fi) | 1988-02-11 | 1998-11-30 | Bristol Myers Squibb Co | Menetelmä yhdistävän välikappaleen omaavien antrasykliini-immunokonjugaattien valmistamiseksi |
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| US5622929A (en) | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| CA2132500A1 (en) | 1994-09-20 | 1996-03-21 | David Lockwood Manning | Methods for predicting the behaviour of breast tumours |
| EP0871490B1 (en) | 1995-12-22 | 2003-03-19 | Bristol-Myers Squibb Company | Branched hydrazone linkers |
| US6130237A (en) | 1996-09-12 | 2000-10-10 | Cancer Research Campaign Technology Limited | Condensed N-aclyindoles as antitumor agents |
| CA2269634C (en) | 1996-10-31 | 2010-08-17 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the breast |
| US6066778A (en) | 1996-11-06 | 2000-05-23 | The Regents Of The University Of Michigan | Transgenic mice expressing APC resistant factor V |
| WO1998034118A1 (en) | 1997-01-30 | 1998-08-06 | Yale University | Diagnostic methods and compositions based on the distribution of rad51 |
| JP2001521744A (ja) | 1997-10-31 | 2001-11-13 | アボット・ラボラトリーズ | 乳房の疾患の検出に有用な試薬および方法 |
| JP2001523472A (ja) | 1997-11-18 | 2001-11-27 | アボット・ラボラトリーズ | 乳房の疾患の検出に有用な試薬および方法 |
| AU2010699A (en) | 1997-12-24 | 1999-07-19 | Corixa Corporation | Compounds for immunotherapy and diagnosis of breast cancer and methods for theiruse |
| JP3422776B2 (ja) | 1998-08-04 | 2003-06-30 | ダイアデクスアス・インコーポレーテッド | 乳癌を診断、監視、病期決定、造影及び治療する新規な方法 |
| JP2002527066A (ja) | 1998-10-15 | 2002-08-27 | カイロン コーポレイション | 転移性乳癌および結腸癌調節遺伝子 |
| AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| US6762020B1 (en) | 1999-03-15 | 2004-07-13 | Protein Design Labs, Inc. | Methods of diagnosing breast cancer |
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| JP2003523207A (ja) | 2000-01-25 | 2003-08-05 | ジェネンテック・インコーポレーテッド | Ｌｉｖ−１関連タンパク質、それをコードするポリヌクレオチド、及び癌の治療へのその利用 |
| WO2001096372A2 (en) | 2000-06-13 | 2001-12-20 | University College Cardiff Consultants Ltd | Zinc transporters proteins and their use in medicinal preparations |
| US6964849B2 (en) | 2001-01-11 | 2005-11-15 | Curagen Corporation | Proteins and nucleic acids encoding same |
| US6884869B2 (en) | 2001-04-30 | 2005-04-26 | Seattle Genetics, Inc. | Pentapeptide compounds and uses related thereto |
| EP1410013A4 (en) | 2001-06-21 | 2006-02-01 | Millennium Pharm Inc | COMPOSITIONS, KITS AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF BREAST AND EGG CANCER |
| AU2002322280A1 (en) | 2001-06-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
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| DE60321041D1 (de) | 2002-03-08 | 2008-06-26 | Pdl Biopharma Inc | Antikörper gegen krebsantigen tmeff2 und seine anwendungen |
| ES2544527T3 (es) | 2002-07-31 | 2015-09-01 | Seattle Genetics, Inc. | Conjugados de fármacos y su uso para tratar el cáncer, una enfermedad autoinmune o una enfermedad infecciosa |
| MXPA05007940A (es) | 2003-01-27 | 2007-06-14 | Biogen Idec Inc | Composiciones y metodos para el tratamiento del cancer usando igsf9 y liv-1. |
| WO2004067564A2 (en) | 2003-01-29 | 2004-08-12 | Protein Design Labs, Inc. | Compositions against cancer antigen liv-1 and uses thereof |
| EP3434275A1 (en) | 2003-11-06 | 2019-01-30 | Seattle Genetics, Inc. | Assay for cancer cells based on the use of auristatin conjugates with antibodies |
| WO2005058961A2 (en) | 2003-12-12 | 2005-06-30 | Amgen Inc. | Antibodies specific for human galanin, and uses thereof |
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| WO2006124269A2 (en) | 2005-05-16 | 2006-11-23 | Amgen Fremont Inc. | Human monoclonal antibodies that bind to very late antigen-1 for the treatment of inflammation and other disorders |
| AU2006287416A1 (en) | 2005-09-07 | 2007-03-15 | Medimmune, Llc | Toxin conjugated Eph receptor antibodies |
| CN101309933A (zh) * | 2005-09-07 | 2008-11-19 | 米迪缪尼有限公司 | 毒素偶联的Eph受体抗体 |
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| US20110165566A1 (en) | 2009-07-09 | 2011-07-07 | Wittliff James L | Methods of optimizing treatment of breast cancer |
| BR112012004777A2 (pt) | 2009-09-03 | 2019-09-24 | Genentech Inc | métodos para tratar diagnósticar e monitorar artrite reumatoide |
| EP3786185A1 (en) * | 2010-12-06 | 2021-03-03 | Seagen Inc. | Humanized antibodies to liv-1 and use of same to treat cancer |
| WO2012125712A2 (en) | 2011-03-14 | 2012-09-20 | Respira Health, Llc | Lung tumor classifier for current and former smokers |
| PT4241849T (pt) | 2011-10-14 | 2024-10-30 | Hoffmann La Roche | Utilizações do inibidor da dimerização de her2 pertuzumab e artigo de fabrico que inclui o mesmo |
| EP2847226A4 (en) * | 2012-05-11 | 2016-05-11 | Merrimack Pharmaceuticals Inc | DOSAGE AND ADMINISTRATION OF BIS SPECIFIC SCFV CONJUGATES IN COMBINATION WITH ANTICROBIAL AGENTS |
| DE202012006349U1 (de) | 2012-07-03 | 2013-07-05 | Schuster Engineering Gmbh | Schiffsladeanordnung |
| ES2738310T3 (es) * | 2012-10-12 | 2020-01-21 | Medimmune Ltd | Pirrolobenzodiazepinas y conjugados de las mismas |
| JP6406647B2 (ja) | 2013-07-02 | 2018-10-17 | 公益財団法人がん研究会 | 細胞性免疫誘導ワクチン |
| ES2754348T3 (es) | 2014-04-10 | 2020-04-17 | Daiichi Sankyo Co Ltd | Conjugado de (anticuerpo anti-HER2)-fármaco |
| MX2020005640A (es) * | 2017-12-01 | 2020-08-20 | Seattle Genetics Inc | Anticuerpos anti-liv1 humanizados para el tratamiento de cancer de mama. |
| WO2020095249A1 (en) | 2018-11-07 | 2020-05-14 | Crispr Therapeutics Ag | Anti-liv1 immune cell cancer therapy |
| GB201908208D0 (en) | 2019-06-10 | 2019-07-24 | Univ College Cardiff Consultants Ltd | An anti-mitotic agent |
| WO2021119105A1 (en) | 2019-12-09 | 2021-06-17 | Seagen Inc. | Combination therapy with liv1-adc and pd-1 antagonist |
-
2017
- 2017-03-15 AU AU2017235545A patent/AU2017235545A1/en not_active Abandoned
- 2017-03-15 CN CN201780013873.8A patent/CN108697801A/zh active Pending
- 2017-03-15 US US16/085,511 patent/US11325980B2/en active Active
- 2017-03-15 SG SG10201912908QA patent/SG10201912908QA/en unknown
- 2017-03-15 EA EA201891968A patent/EA201891968A1/ru unknown
- 2017-03-15 WO PCT/US2017/022541 patent/WO2017161007A1/en not_active Ceased
- 2017-03-15 KR KR1020227039721A patent/KR20220157515A/ko not_active Ceased
- 2017-03-15 KR KR1020237041743A patent/KR20230169462A/ko not_active Withdrawn
- 2017-03-15 EP EP17767448.8A patent/EP3429626A4/en not_active Withdrawn
- 2017-03-15 SG SG11201807526SA patent/SG11201807526SA/en unknown
- 2017-03-15 MX MX2018010847A patent/MX2018010847A/es unknown
- 2017-03-15 MA MA045324A patent/MA45324A/fr unknown
- 2017-03-15 CA CA3016485A patent/CA3016485A1/en active Pending
- 2017-03-15 BR BR112018068129-6A patent/BR112018068129A2/pt active Search and Examination
- 2017-03-15 JP JP2018546036A patent/JP2019508433A/ja active Pending
- 2017-03-15 KR KR1020187028273A patent/KR20180121571A/ko not_active Ceased
-
2018
- 2018-09-02 IL IL261505A patent/IL261505A/en unknown
- 2018-09-07 MX MX2023008849A patent/MX2023008849A/es unknown
-
2022
- 2022-01-20 JP JP2022006944A patent/JP2022058676A/ja active Pending
- 2022-10-17 US US18/047,243 patent/US20230235083A1/en not_active Abandoned
-
2024
- 2024-03-14 JP JP2024039750A patent/JP2024075639A/ja active Pending
- 2024-03-21 AU AU2024201856A patent/AU2024201856A1/en not_active Abandoned
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