ECSP099178A - Método de tratamiento del ictus con un trombolítico - Google Patents

Método de tratamiento del ictus con un trombolítico

Info

Publication number
ECSP099178A
ECSP099178A EC2009009178A ECSP099178A ECSP099178A EC SP099178 A ECSP099178 A EC SP099178A EC 2009009178 A EC2009009178 A EC 2009009178A EC SP099178 A ECSP099178 A EC SP099178A EC SP099178 A ECSP099178 A EC SP099178A
Authority
EC
Ecuador
Prior art keywords
treatment
administration
thrombolitic
ictus
embolate
Prior art date
Application number
EC2009009178A
Other languages
English (en)
Inventor
Peter Kuebler
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38835003&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP099178(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ECSP099178A publication Critical patent/ECSP099178A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Un método para el tratamiento del ictus isquémico agudo en humanos comprende la administración de tenecteplasa al humano en una dosis total de 0,05 a 0,5 mg/kg aproximadamente (a) mediante administración en embolada de una dosis inicial comprendida entre alrededor de 0,05 y 0,15 mg/kg, seguida de infusión de una cantidad igual a la dosis total menos la dosis inicial durante un periodo de 50 a 90 minutos aproximadamente, o (b) mediante administración en embolada. También se describen los kits para aplicar este método.
EC2009009178A 2006-08-29 2009-03-12 Método de tratamiento del ictus con un trombolítico ECSP099178A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82386806P 2006-08-29 2006-08-29

Publications (1)

Publication Number Publication Date
ECSP099178A true ECSP099178A (es) 2009-06-30

Family

ID=38835003

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2009009178A ECSP099178A (es) 2006-08-29 2009-03-12 Método de tratamiento del ictus con un trombolítico

Country Status (21)

Country Link
US (2) US20080107641A1 (es)
EP (1) EP2056856B1 (es)
JP (1) JP5785687B2 (es)
KR (1) KR20090045405A (es)
CN (1) CN101505785A (es)
AU (1) AU2007290277B2 (es)
BR (1) BRPI0716143A2 (es)
CA (1) CA2661012C (es)
CO (1) CO6150188A2 (es)
EA (1) EA015573B1 (es)
EC (1) ECSP099178A (es)
IL (2) IL196987A (es)
MX (1) MX2009001918A (es)
MY (1) MY163119A (es)
NO (1) NO342302B1 (es)
NZ (1) NZ574767A (es)
SG (3) SG10201501498VA (es)
TW (1) TWI439282B (es)
UA (1) UA97486C2 (es)
WO (1) WO2008027687A2 (es)
ZA (1) ZA200900957B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
US8030350B2 (en) 2005-02-24 2011-10-04 Diffusion Pharmaceuticals Llc Trans carotenoids, their synthesis, formulation and uses
TWI439282B (zh) 2006-08-29 2014-06-01 Genentech Inc 以血栓溶解劑治療中風之方法
MX2009010988A (es) 2007-04-13 2010-03-15 Diffusion Pharmaceuticals Llc Uso de trans-carotenoides bipolares como un tratamiento previo y en el tratamiento de una enfermedad vascular periferica.
US9034007B2 (en) 2007-09-21 2015-05-19 Insera Therapeutics, Inc. Distal embolic protection devices with a variable thickness microguidewire and methods for their use
JP2012513812A (ja) * 2008-12-24 2012-06-21 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Ｍｒ卒中検出および処置による心臓介入のシステム、方法および装置
EP2445339B1 (en) 2009-06-22 2019-08-07 Diffusion Pharmaceuticals LLC Diffusion enhancing compound and its use with a thrombolytic
JP5762414B2 (ja) * 2009-08-24 2015-08-12 ハフ イヤ インスティテュート 急性音響外傷の治療方法
ES2654945T3 (es) 2010-06-02 2018-02-15 Diffusion Pharmaceuticals Llc Formulaciones orales de carotenoides trans bipolares
MY171723A (en) * 2010-12-23 2019-10-24 Gennova Biopharmaceuticals Ltd Pharmaceutical compositions of tenecteplase
WO2014062888A1 (en) 2012-10-18 2014-04-24 University Of South Florida Compositions and methods for treating stroke
US8715315B1 (en) 2013-03-15 2014-05-06 Insera Therapeutics, Inc. Vascular treatment systems
US8679150B1 (en) 2013-03-15 2014-03-25 Insera Therapeutics, Inc. Shape-set textile structure based mechanical thrombectomy methods
JP6437517B2 (ja) 2013-03-15 2018-12-12 インセラ セラピューティクス，インク． 血管治療装置及び方法
US8715314B1 (en) 2013-03-15 2014-05-06 Insera Therapeutics, Inc. Vascular treatment measurement methods
US10220008B2 (en) 2013-08-14 2019-03-05 Stc.Unm Treatment and prevention of stroke and other neurological disorders
MX383595B (es) * 2014-10-21 2025-03-14 Gennova Biopharmaceuticals Ltd Proceso novedoso de purificacion para el aislamiento y produccion comercial de tnk-tpa recombinante (tenecteplasa)
CN108697423A (zh) 2016-02-16 2018-10-23 伊瑟拉医疗公司 抽吸装置和锚定的分流装置
WO2017165667A1 (en) 2016-03-24 2017-09-28 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer
EP3573635B1 (en) * 2017-01-24 2021-05-12 Ekos Corporation Method for the treatment of thromboembolism
EP3624832B1 (en) * 2017-05-16 2025-08-20 Institut National de la Santé et de la Recherche Médicale Methods and pharmaceutical compositions for the treatment of acute ischemic stroke
US10426424B2 (en) 2017-11-21 2019-10-01 General Electric Company System and method for generating and performing imaging protocol simulations
WO2021158799A1 (en) * 2020-02-04 2021-08-12 The Regents Of The University Of Colorado, A Body Corporate Prophylactic uses of annexin a2
MX2022010160A (es) * 2020-02-19 2022-10-10 Nono Inc Tratamiento de combinación de apoplejia con inhibidor de psd-95 escindible por plasmina y reperfusión.
CN114984197A (zh) * 2022-07-01 2022-09-02 江苏丰华生物制药有限公司 替奈普酶在制备用于治疗急性缺血性卒中的药物组合物中的应用
CN115487294A (zh) * 2022-07-12 2022-12-20 上海丰华天力通生物医药有限公司 替奈普酶在制备用于治疗轻型缺血性卒中的药物组合物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
EP0786257B1 (en) 1992-06-03 2003-07-30 Genentech, Inc. Tissue plasminogen activator glycosylation variants with improved therapeutic properties
JP2002173447A (ja) * 2000-09-29 2002-06-21 Yamanouchi Pharmaceut Co Ltd 脳塞栓症治療用医薬組成物
US7084118B2 (en) * 2002-02-22 2006-08-01 Genentech, Inc. Combination treatment with t-PA variant and low molecular weight heparin
US20030180282A1 (en) * 2002-03-25 2003-09-25 Victor Serebruany Method of treatment of thrombotic events
US20070014779A1 (en) * 2002-11-14 2007-01-18 Genentech, Inc. Plasminogen activator variant formulations
WO2006094120A2 (en) * 2005-03-02 2006-09-08 The Regents Of The University Of California Treatment for embolic stroke
TWI439282B (zh) 2006-08-29 2014-06-01 Genentech Inc 以血栓溶解劑治療中風之方法

Also Published As

Publication number Publication date
NZ574767A (en) 2012-02-24
HK1131054A1 (en) 2010-01-15
TW200817033A (en) 2008-04-16
NO342302B1 (no) 2018-04-30
WO2008027687A3 (en) 2008-05-22
UA97486C2 (ru) 2012-02-27
IL196987A (en) 2016-10-31
NO20091296L (no) 2009-05-28
CO6150188A2 (es) 2010-04-20
MX2009001918A (es) 2009-03-06
US9023346B2 (en) 2015-05-05
ZA200900957B (en) 2010-05-26
WO2008027687A2 (en) 2008-03-06
BRPI0716143A2 (pt) 2013-11-26
MY163119A (en) 2017-08-15
TWI439282B (zh) 2014-06-01
AU2007290277B2 (en) 2013-04-11
JP5785687B2 (ja) 2015-09-30
US20080107641A1 (en) 2008-05-08
EA200970237A1 (ru) 2009-08-28
CA2661012A1 (en) 2008-03-06
IL196987A0 (en) 2011-08-01
KR20090045405A (ko) 2009-05-07
EP2056856B1 (en) 2015-01-14
US20120164157A1 (en) 2012-06-28
SG174753A1 (en) 2011-10-28
EP2056856A2 (en) 2009-05-13
JP2010502629A (ja) 2010-01-28
IL248176A0 (en) 2016-11-30
SG10201501498VA (en) 2015-04-29
CN101505785A (zh) 2009-08-12
AU2007290277A1 (en) 2008-03-06
EA015573B1 (ru) 2011-10-31
CA2661012C (en) 2019-03-19
SG10201804944XA (en) 2018-07-30

Similar Documents

Publication Publication Date Title
ECSP099178A (es) Método de tratamiento del ictus con un trombolítico
AR044007A1 (es) Metodos para el tratamiento de la enfermedad de parkinson
CL2011000916A1 (es) Uso de una combinacion de un inhibidor de proteasoma epoxicetona peptidica o una sal farmaceutica aceptable del mismo, y uno o mas de otros agentes terapeuticos para tratar el cancer.
AR109170A2 (es) Esfingomielinasa ácida para uso en la prevención o el tratamiento de la enfermedad de niemann-pick a o b en un paciente
SV2015005115A (es) Derivados de la pirazolopirrolidina y su uso en el tratamiento de enfermedades
CO6331425A2 (es) Composiciones que comprenden n-(3,4-difluoro-2-(2-fluoro-4-yodofenilamino)6-metoxifenil)-1-(2,3-dihidroxiproxipropil)ciclopropan-1-sulfamida
CR11418A (es) Trans-clomifeno para el sindrome metabolico
AR067903A1 (es) Metodo para tratar la depresion mediada por estres
MX2018009173A (es) Uso de estimuladores de guanilato ciclasa soluble (sgc) para el tratamiento de esteatohepatitis no alcohólica (nash).
MX2023000187A (es) Dosificacion de vibegron para el tratamiento de vejiga sobreactiva.
AR112015A1 (es) Composiciones sólidas para administración oral
CO6270217A2 (es) Formulaciones galenicas de alisquireno y valsartan
MX367209B (es) Una composición intravenosa que comprende ibuprofeno y paracetamol en combinación.
CL2020002544A1 (es) Inhibidor de ret para uso en tratar cáncer que tiene una alteración de ret
MX2022015629A (es) Uso de vibegron para tratar vejiga sobreactiva.
AR111374A1 (es) Uso de lik066 en pacientes con insuficiencia cardíaca
MX2009005798A (es) Recuperacion de apoplejia.
DK1781277T3 (da) Kombinationssammensætning, der omfatter Ibuprofen og Paracetamol
ES2563068T3 (es) Tratamiento de esclerosis múltiple (MS) con Campath-1H
CL2012003119A1 (es) Composicion farmaceutica para inyeccion que compende una solucion acuosa de ibuprofeno y trometamol, en que la concentracion de ibuprofeno esta entre 2 y 6 mg/ml, la concentracion de trometamol esta entre 1.8 y 5.8 mg/ml, y el ph esta entre 7,0 y 9,5; y su uso para el tratamiento del dolor, la inflamacion o la fiebre.
MX2021011289A (es) Composiciones que comprenden moduladores de isoenzima m2 muscular de piruvato cinasa pkm2 y metodos de tratamiento que usan las mismas.
CO2022004572A2 (es) Tratamiento de la diabetes mellitus tipo 2
CO5700723A2 (es) Uso de un derivado de amina ciclica especifico o de sus sales farmaceuticamente aceptables para tratar y prevenir la insuficiencia cardiaca
CL2004000767A1 (es) Unidad de dosificacion oral que comprende un agente antagonista de bombas de protones y excipientes de caracter basico; procedimiento para su preparacion, utiles para tratar enfermedades causadas por una secrecion aumentada de acidos gastricos.
RU2007122391A (ru) S-миртазапин для лечения приливов