JP2010090149A5 - - Google Patents
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- Publication number
- JP2010090149A5 JP2010090149A5 JP2009279362A JP2009279362A JP2010090149A5 JP 2010090149 A5 JP2010090149 A5 JP 2010090149A5 JP 2009279362 A JP2009279362 A JP 2009279362A JP 2009279362 A JP2009279362 A JP 2009279362A JP 2010090149 A5 JP2010090149 A5 JP 2010090149A5
- Authority
- JP
- Japan
- Prior art keywords
- cooh
- following formula
- carbon atoms
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Claims (4)
- 薬学的担体、および請求項1または2記載の化合物のいずれかを含む、薬学的組成物。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34649202P | 2002-01-07 | 2002-01-07 | |
US60/346,492 | 2002-01-07 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003557380A Division JP4571408B2 (ja) | 2002-01-07 | 2003-01-07 | 癌治療薬としての、s−ジメチルアルシノ−チオコハク酸、s−ジメチルアルシノ−2−チオ安息香酸、s−(ジメチルアルシノ)グルタチオン |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013172071A Division JP2013237701A (ja) | 2002-01-07 | 2013-08-22 | 癌治療薬としての、s−ジメチルアルシノ−チオコハク酸、s−ジメチルアルシノ−2−チオ安息香酸、s−(ジメチルアルシノ)グルタチオン |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2010090149A JP2010090149A (ja) | 2010-04-22 |
JP2010090149A5 true JP2010090149A5 (ja) | 2012-03-01 |
JP5603593B2 JP5603593B2 (ja) | 2014-10-08 |
Family
ID=23359639
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003557380A Expired - Lifetime JP4571408B2 (ja) | 2002-01-07 | 2003-01-07 | 癌治療薬としての、s−ジメチルアルシノ−チオコハク酸、s−ジメチルアルシノ−2−チオ安息香酸、s−(ジメチルアルシノ)グルタチオン |
JP2009279362A Expired - Fee Related JP5603593B2 (ja) | 2002-01-07 | 2009-12-09 | 癌治療薬としての、s−ジメチルアルシノ−チオコハク酸、s−ジメチルアルシノ−2−チオ安息香酸、s−(ジメチルアルシノ)グルタチオン |
JP2013172071A Pending JP2013237701A (ja) | 2002-01-07 | 2013-08-22 | 癌治療薬としての、s−ジメチルアルシノ−チオコハク酸、s−ジメチルアルシノ−2−チオ安息香酸、s−(ジメチルアルシノ)グルタチオン |
JP2015051753A Pending JP2015120745A (ja) | 2002-01-07 | 2015-03-16 | 癌治療薬としての、s−ジメチルアルシノ−チオコハク酸、s−ジメチルアルシノ−2−チオ安息香酸、s−(ジメチルアルシノ)グルタチオン |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003557380A Expired - Lifetime JP4571408B2 (ja) | 2002-01-07 | 2003-01-07 | 癌治療薬としての、s−ジメチルアルシノ−チオコハク酸、s−ジメチルアルシノ−2−チオ安息香酸、s−(ジメチルアルシノ)グルタチオン |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2013172071A Pending JP2013237701A (ja) | 2002-01-07 | 2013-08-22 | 癌治療薬としての、s−ジメチルアルシノ−チオコハク酸、s−ジメチルアルシノ−2−チオ安息香酸、s−(ジメチルアルシノ)グルタチオン |
JP2015051753A Pending JP2015120745A (ja) | 2002-01-07 | 2015-03-16 | 癌治療薬としての、s−ジメチルアルシノ−チオコハク酸、s−ジメチルアルシノ−2−チオ安息香酸、s−(ジメチルアルシノ)グルタチオン |
Country Status (6)
Country | Link |
---|---|
US (4) | US6911471B2 (ja) |
EP (3) | EP1474128B1 (ja) |
JP (4) | JP4571408B2 (ja) |
AU (1) | AU2003207455B2 (ja) |
CA (1) | CA2472633C (ja) |
WO (1) | WO2003057012A2 (ja) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1474128B1 (en) | 2002-01-07 | 2016-06-01 | Board Of Regents, The University Of Texas System | S-dimethylarsino-thiosuccinic acid, s-dimethylarsino-2-thiobenzoic acid, s-(dimethylarsino)glutathione as treatments for cancer |
AU2011204901B2 (en) * | 2004-07-16 | 2013-09-12 | Board Of Regents, The University Of Texas System | Compounds and methods for treatment of cancer |
TWI411431B (zh) * | 2004-07-16 | 2013-10-11 | Texas A & M Univ Sys | 有機砷化合物、其用於治療癌症之用途及包含其之醫藥組成物 |
ES2531159T3 (es) * | 2005-07-29 | 2015-03-11 | Solasia Pharma K K | Compuestos y métodos para el tratamiento del cáncer |
WO2007082104A2 (en) * | 2006-01-13 | 2007-07-19 | The Texas A & M University System | Compounds and methods for the treatment of cancer |
TW200829261A (en) | 2006-09-29 | 2008-07-16 | Ziopharm Oncology Inc | Method for controlling angiogenesis in animals |
CA2668010C (en) * | 2006-11-01 | 2015-03-24 | Newsouth Innovations Pty Limited | Organo-arsenoxide compounds and use thereof |
AU2008325243B2 (en) * | 2007-11-02 | 2014-07-03 | Solasia Pharma K.K. | Combination therapy with organic arsenicals |
CN101874034A (zh) * | 2007-12-12 | 2010-10-27 | Zio医药肿瘤学公司 | 用于治疗癌症的化合物和方法 |
AU2009259535B2 (en) * | 2008-05-28 | 2016-01-21 | Basf Se | Means and methods for assessing liver enzyme induction |
EP3388111B1 (en) | 2008-08-20 | 2021-09-29 | Solasia Pharma K.K. | Organoarsenic compound for the treatment of cancer |
WO2011133475A2 (en) * | 2010-04-19 | 2011-10-27 | Sri International | Compositions and method for the treatment of multiple myeloma |
KR20160086960A (ko) * | 2013-12-05 | 2016-07-20 | 솔레이지아 파마 가부시키가이샤 | 암 치료를 위한 화합물 및 방법 |
CN112941027B (zh) * | 2021-03-19 | 2021-11-02 | 苏州大学 | 二甲基亚胂酸致人角质形成细胞恶性转化细胞株及其应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2349729A (en) * | 1940-08-24 | 1944-05-23 | Parke Davis & Co | Therapeutic arsenic preparation |
US2701812A (en) * | 1951-06-26 | 1955-02-08 | Dainippon Pharmaceutical Co | Diarylarsenious acid derivatives and the preparation thereof |
DE3229565A1 (de) * | 1982-08-07 | 1984-02-16 | Etschenberg, Eugen, Dr., 5000 Köln | Arsenhaltige nucleoside |
FR2640269B1 (fr) * | 1988-12-13 | 1991-03-15 | Maes Ludo | Composes organometalliques, leurs modes de preparation et compositions pharmaceutiques les contenant |
PT1391206E (pt) * | 1997-10-15 | 2008-08-13 | Polarx Biopharmaceuticals Inc | Composições farmacêuticas compreendendo trióxido de arsénico para o tratamento de linfoma não-hodgkin |
PT1964557E (pt) | 1997-11-10 | 2013-02-20 | Sloan Kettering Inst Cancer | Processo para a produção de formulações de trióxido de arsénio |
CN1233476A (zh) * | 1998-04-24 | 1999-11-03 | 陆道培 | 治疗急性白血病的药物及其制备方法 |
EP1002537A1 (en) | 1998-10-30 | 2000-05-24 | Assistance Publique, Hopitaux De Paris | Use of melarsoprol for the manufacture of a medicament for treating B-cell lymphoproliferative diseases, such as multiple myeloma |
US6191123B1 (en) * | 1999-03-19 | 2001-02-20 | Parker Hughes Institute | Organic-arsenic compounds |
AUPQ296799A0 (en) | 1999-09-20 | 1999-10-14 | Unisearch Limited | A cell-membrane impermeable trivalent organoarsenical derivative and use thereof |
WO2001080832A2 (en) | 2000-04-26 | 2001-11-01 | Oregon Health Sciences University | Administration of a thiol-based chemoprotectant compound |
AUPR379801A0 (en) | 2001-03-19 | 2001-04-12 | Unisearch Limited | Use of a substantially cell membrane impermeable compound for treating arthritis |
AUPR598901A0 (en) | 2001-06-28 | 2001-07-19 | Unisearch Limited | Inhibition of angiogenesis by targeting protein tyrosine phosphatases |
CA2417008A1 (en) | 2001-07-06 | 2003-01-16 | Cochlear Limited | Configuration of implanted devices |
EP1474128B1 (en) * | 2002-01-07 | 2016-06-01 | Board Of Regents, The University Of Texas System | S-dimethylarsino-thiosuccinic acid, s-dimethylarsino-2-thiobenzoic acid, s-(dimethylarsino)glutathione as treatments for cancer |
ES2330519T3 (es) | 2002-11-07 | 2009-12-11 | Newsouth Innovations Pty Limited | Inducion de la transicion de permeabilidad mitocondrial. |
TWI411431B (zh) | 2004-07-16 | 2013-10-11 | Texas A & M Univ Sys | 有機砷化合物、其用於治療癌症之用途及包含其之醫藥組成物 |
CA2668010C (en) | 2006-11-01 | 2015-03-24 | Newsouth Innovations Pty Limited | Organo-arsenoxide compounds and use thereof |
-
2003
- 2003-01-07 EP EP03705662.9A patent/EP1474128B1/en not_active Expired - Lifetime
- 2003-01-07 CA CA2472633A patent/CA2472633C/en not_active Expired - Fee Related
- 2003-01-07 AU AU2003207455A patent/AU2003207455B2/en not_active Ceased
- 2003-01-07 WO PCT/US2003/000281 patent/WO2003057012A2/en active Application Filing
- 2003-01-07 JP JP2003557380A patent/JP4571408B2/ja not_active Expired - Lifetime
- 2003-01-07 EP EP11187256A patent/EP2462932A1/en not_active Withdrawn
- 2003-01-07 US US10/337,969 patent/US6911471B2/en not_active Expired - Lifetime
- 2003-01-07 EP EP20110187261 patent/EP2420229A1/en not_active Withdrawn
-
2005
- 2005-01-13 US US11/035,178 patent/US6995188B2/en not_active Expired - Lifetime
-
2006
- 2006-02-06 US US11/349,043 patent/US7619000B2/en not_active Expired - Lifetime
-
2007
- 2007-08-20 US US11/894,807 patent/US20080090904A1/en not_active Abandoned
-
2009
- 2009-12-09 JP JP2009279362A patent/JP5603593B2/ja not_active Expired - Fee Related
-
2013
- 2013-08-22 JP JP2013172071A patent/JP2013237701A/ja active Pending
-
2015
- 2015-03-16 JP JP2015051753A patent/JP2015120745A/ja active Pending
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