JP2010065046A5 - - Google Patents

Download PDF

Info

Publication number
JP2010065046A5
JP2010065046A5 JP2009251464A JP2009251464A JP2010065046A5 JP 2010065046 A5 JP2010065046 A5 JP 2010065046A5 JP 2009251464 A JP2009251464 A JP 2009251464A JP 2009251464 A JP2009251464 A JP 2009251464A JP 2010065046 A5 JP2010065046 A5 JP 2010065046A5
Authority
JP
Japan
Prior art keywords
seq
peptide
amino acid
sequence
cell epitope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009251464A
Other languages
English (en)
Japanese (ja)
Other versions
JP5345920B2 (ja
JP2010065046A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2010065046A publication Critical patent/JP2010065046A/ja
Publication of JP2010065046A5 publication Critical patent/JP2010065046A5/ja
Application granted granted Critical
Publication of JP5345920B2 publication Critical patent/JP5345920B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2009251464A 2002-04-19 2009-10-30 アルツハイマー病の処置のための免疫学的方法および組成物 Expired - Fee Related JP5345920B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37391402P 2002-04-19 2002-04-19
US60/373,914 2002-04-19

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2003586180A Division JP4662719B2 (ja) 2002-04-19 2003-04-07 アルツハイマー病の処置のための免疫学的方法および組成物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012249078A Division JP2013075898A (ja) 2002-04-19 2012-11-13 アルツハイマー病の処置のための免疫学的方法および組成物

Publications (3)

Publication Number Publication Date
JP2010065046A JP2010065046A (ja) 2010-03-25
JP2010065046A5 true JP2010065046A5 (enExample) 2010-11-25
JP5345920B2 JP5345920B2 (ja) 2013-11-20

Family

ID=29251102

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2003586180A Expired - Fee Related JP4662719B2 (ja) 2002-04-19 2003-04-07 アルツハイマー病の処置のための免疫学的方法および組成物
JP2009251464A Expired - Fee Related JP5345920B2 (ja) 2002-04-19 2009-10-30 アルツハイマー病の処置のための免疫学的方法および組成物
JP2012249078A Withdrawn JP2013075898A (ja) 2002-04-19 2012-11-13 アルツハイマー病の処置のための免疫学的方法および組成物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2003586180A Expired - Fee Related JP4662719B2 (ja) 2002-04-19 2003-04-07 アルツハイマー病の処置のための免疫学的方法および組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012249078A Withdrawn JP2013075898A (ja) 2002-04-19 2012-11-13 アルツハイマー病の処置のための免疫学的方法および組成物

Country Status (17)

Country Link
US (5) US20030232758A1 (enExample)
EP (2) EP2330113B1 (enExample)
JP (3) JP4662719B2 (enExample)
KR (1) KR100994748B1 (enExample)
CN (1) CN100360555C (enExample)
AT (1) ATE514707T1 (enExample)
AU (1) AU2003218560B2 (enExample)
CA (1) CA2481952C (enExample)
ES (1) ES2368907T3 (enExample)
IL (3) IL164643A0 (enExample)
MX (1) MXPA04010255A (enExample)
NO (2) NO335192B1 (enExample)
NZ (1) NZ536064A (enExample)
PL (1) PL209696B1 (enExample)
SG (1) SG173214A1 (enExample)
WO (1) WO2003089460A1 (enExample)
ZA (1) ZA200408811B (enExample)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1309341A2 (en) 2000-07-07 2003-05-14 Lars Lannfelt Prevention and treatment of alzheimer's disease
CA2504349A1 (en) * 2001-11-02 2003-05-15 Diagenics International Corporation Monoclonal antibodies specific for beta-amyloid
US20050106626A1 (en) * 2002-10-20 2005-05-19 George Pieczenik Ligand binding of amyloid peptide protein epitope
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
SE0401601D0 (sv) * 2004-06-21 2004-06-21 Bioarctic Neuroscience Ab Protofibril specific antibodies and uses thereof
US8193250B2 (en) 2004-10-22 2012-06-05 Mount Sinai School Of Medicine Compositions and methods for treating alzheimer's disease and related disorders and promoting a healthy nervous system
US20090123952A1 (en) * 2004-11-12 2009-05-14 Pfizer, Inc. Method of Measuring Amyloid-Beta Peptides
CA2628703C (en) 2005-11-30 2019-10-29 Abbott Laboratories Anti-a.beta. globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies
DK1976877T4 (en) 2005-11-30 2017-01-16 Abbvie Inc Monoclonal antibodies to amyloid beta protein and uses thereof
MX358175B (es) 2005-12-12 2018-08-08 Ac Immune Sa Anticuerpos monoclonales especificos 1-42 beta con propiedades terapeuticas.
CA2638775A1 (en) 2006-02-22 2007-08-30 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Peptide vaccine for inducing production of anti-amyloid-.beta.-peptide antibody
RS51723B2 (sr) 2006-03-23 2018-03-30 Bioarctic Neuroscience Ab Poboljšana antitela selektivna za protofibrile i njihova primena
US8101578B2 (en) 2006-04-28 2012-01-24 Kagoshima University Amyloid [β] Beta fibrillogenesis-inhibiting peptide
PL2468770T3 (pl) 2006-07-14 2018-07-31 Ac Immune S.A. Humanizowane przeciwciało przeciw amyloidowi beta
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
WO2008143708A2 (en) * 2006-12-07 2008-11-27 Mayo Foundation For Medical Education And Research Methods and materials related to anti-amyloid antibodies
HRP20140049T1 (hr) 2007-01-05 2014-02-28 University Of Zürich Anti beta-amiloid antitijela i njihova upotreba
WO2008104386A2 (en) 2007-02-27 2008-09-04 Abbott Gmbh & Co. Kg Method for the treatment of amyloidoses
CN101668525A (zh) 2007-03-01 2010-03-10 前体生物药物股份公司 谷氨酰胺酰环化酶抑制剂的新用途
EP2142514B1 (en) 2007-04-18 2014-12-24 Probiodrug AG Thiourea derivatives as glutaminyl cyclase inhibitors
US8048420B2 (en) 2007-06-12 2011-11-01 Ac Immune S.A. Monoclonal antibody
US8613923B2 (en) 2007-06-12 2013-12-24 Ac Immune S.A. Monoclonal antibody
DK2238166T3 (da) 2007-10-05 2014-01-27 Ac Immune Sa Anvendelse af et anti-amyloid-beta-antistof ved øjensygdomme
EP2328908A4 (en) * 2008-08-28 2012-11-28 Univ New York State Res Found TREATMENT OF AMYLOID DISEASES USING BASIC PROTEINS OF MYELINE OR FRAGMENTS DESCRIBED
JP5709097B2 (ja) * 2008-11-28 2015-04-30 北興化学工業株式会社 ワクチンを蓄積する形質転換ダイズ植物およびその利用
US8912145B2 (en) 2008-11-28 2014-12-16 Hokko Chemical Industry Co., Ltd. Vaccine composition for prophylaxis and/or therapy of Alzheimer's disease
CN101797493B (zh) * 2009-02-06 2014-05-21 上海抗体药物国家工程研究中心有限公司 一种在反应釜中制备亲和层析介质的方法
CN101486768B (zh) * 2009-02-25 2012-05-30 吉林大学 一种用于治疗阿尔茨海默氏病的抗原蛋白及蛋白基因
WO2010124028A2 (en) * 2009-04-21 2010-10-28 Vasylyev Sergiy V Light collection and illumination systems employing planar waveguide
PL2475428T3 (pl) 2009-09-11 2015-12-31 Probiodrug Ag Pochodne heterocykliczne jako inhibitory cyklazy glutaminowej
WO2011107530A2 (en) 2010-03-03 2011-09-09 Probiodrug Ag Novel inhibitors
KR101790806B1 (ko) 2010-03-10 2017-11-20 프로비오드룩 아게 글루타미닐 사이클라제(qc, ec 2.3.2.5)의 헤테로사이클릭 억제제
CN104744591B (zh) 2010-04-15 2022-09-27 Abbvie德国有限责任两合公司 β淀粉样蛋白结合蛋白
WO2011131748A2 (en) 2010-04-21 2011-10-27 Probiodrug Ag Novel inhibitors
AU2011282536B2 (en) 2010-07-30 2015-12-24 Ac Immune S.A. Safe and functional humanized anti beta-amyloid antibody
WO2012024187A1 (en) 2010-08-14 2012-02-23 Abbott Laboratories Amyloid-beta binding proteins
US20120328605A1 (en) * 2010-10-27 2012-12-27 Daniel Larocque Compositions and uses
WO2012123563A1 (en) 2011-03-16 2012-09-20 Probiodrug Ag Benz imidazole derivatives as inhibitors of glutaminyl cyclase
DE102011057019A1 (de) * 2011-12-23 2013-06-27 Forschungszentrum Jülich GmbH Standard zur Quantifizierung von pathogenen Aggregaten aus körpereigenen Proteinen
BR112014010879A2 (pt) * 2012-01-20 2017-06-13 Annapragada Ananth métodos e composições para caracterizar objetivamente imagens médicas
US9534048B2 (en) * 2012-08-24 2017-01-03 University Health Network Antibodies to TTR and methods of use
KR102117969B1 (ko) * 2012-09-12 2020-06-04 뉴리뮨 홀딩 아게 인간 섬 아밀로이드 폴리펩티드(hiapp) 특이적 항체 및 이들의 용도
MX370725B (es) 2012-10-15 2019-12-20 Medimmune Ltd Anticuerpos contra el beta-amiloide.
EP3027205A4 (en) 2013-07-28 2017-07-19 Qantu Therapeutics, Inc. Vaccine formulations that induce a th2 immune response
CN106659736A (zh) 2014-04-29 2017-05-10 阿费里斯股份公司 阿尔茨海默病(ad)的治疗和预防
PE20170768A1 (es) 2014-07-10 2017-07-04 Eisai Randd Man Co Ltd Anticuerpos de union a protofibrillas ab mejorados
MA41115A (fr) 2014-12-02 2017-10-10 Biogen Int Neuroscience Gmbh Procédé de traitement de la maladie d'alzheimer
CN108699134A (zh) * 2015-12-10 2018-10-23 国家生物技术研究所公司 淀粉样β-蛋白前体抑制剂结构域的变体
ES2848720T3 (es) * 2016-11-25 2021-08-11 Genuv Inc Composición para promover la diferenciación y la protección de células madre neurales y método para inducir la regeneración neural utilizando la misma
WO2019023247A1 (en) 2017-07-25 2019-01-31 Immutics, Inc. TREATMENT OF CANCER BY BLOCKING THE INTERACTION OF TIM-3 AND ITS LIGAND
SMT202300129T1 (it) 2017-08-22 2023-05-12 Biogen Ma Inc Composizioni farmaceutiche contenenti anticorpi anti-beta amiloide
DK3461819T3 (da) 2017-09-29 2020-08-10 Probiodrug Ag Inhibitorer af glutaminylcyklase
AR113792A1 (es) 2017-10-25 2020-06-10 Janssen Pharmaceuticals Inc Composiciones de péptidos tau fosforilados y sus usos
CA3099946A1 (en) * 2018-05-18 2019-11-21 Universite Laval Use of nod2 agonist for the treatment, prophylaxis and/or delay of the onset of multiple sclerosis and alzheimer's disease
EP3918323A4 (en) 2019-01-30 2022-12-28 TrueBinding, Inc. ANTI-GAL3 ANTIBODIES AND USES THEREOF
BR112021014794A2 (pt) * 2019-02-08 2021-10-05 Ac Immune S.A. Método de administração segura de vacina de peptídeo de tau fosforilada
CN113614101B (zh) * 2019-02-22 2024-07-16 洛约拉马利蒙特大学 淀粉样肽的变体
EP3965817A4 (en) 2019-04-24 2023-11-22 Janssen Pharmaceuticals, Inc. HETEROLOGICAL ADMINISTRATION OF TAU VACCINES
MX2022009607A (es) * 2020-02-05 2022-09-02 Sumitomo Pharma Co Ltd Agente de determinacion y metodo de determinacion de taupatia y enfermedades relacionadas con la demencia.
TW202144387A (zh) * 2020-02-11 2021-12-01 美商聯合生物醫學公司 針對胰島澱粉樣多肽(iapp)的胜肽免疫原及其預防和治療與聚集iapp相關疾病的製劑
WO2021242776A2 (en) 2020-05-26 2021-12-02 Truebinding, Inc. Methods of treating inflammatory diseases by blocking galectin-3
CN115925987A (zh) * 2022-02-28 2023-04-07 安域生物科技(杭州)有限公司 基于β-淀粉样蛋白修饰的抗原多肽及其应用
CN115786260B (zh) * 2022-12-26 2024-08-20 海南大学 Aβ42-hIAPP共寡聚化物诱导的AD脑类器官病理模型方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235877A (en) 1979-06-27 1980-11-25 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4666829A (en) * 1985-05-15 1987-05-19 University Of California Polypeptide marker for Alzheimer's disease and its use for diagnosis
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5814318A (en) 1990-08-29 1998-09-29 Genpharm International Inc. Transgenic non-human animals for producing heterologous antibodies
US5770429A (en) 1990-08-29 1998-06-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5874299A (en) 1990-08-29 1999-02-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
EP0671948B1 (en) 1992-06-25 1997-08-13 SMITHKLINE BEECHAM BIOLOGICALS s.a. Vaccine composition containing adjuvants
US5766846A (en) * 1992-07-10 1998-06-16 Athena Neurosciences Methods of screening for compounds which inhibit soluble β-amyloid peptide production
US5840294A (en) 1993-03-29 1998-11-24 Queen's University At Kingston Method for treating amyloidosis
US5759551A (en) 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
ATE221387T1 (de) * 1993-04-27 2002-08-15 United Biomedical Inc Immunogene lhrh peptidkonstrukion und synthetische, universale immunstimulatoren als impfstoffe
US5744144A (en) 1993-07-30 1998-04-28 University Of Pittsburgh University Patent Committee Policy And Procedures Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
WO1997007402A1 (en) 1995-08-17 1997-02-27 The Ontario Cancer Institute Protein fibril assembly assay
US7964192B1 (en) * 1997-12-02 2011-06-21 Janssen Alzheimer Immunotherapy Prevention and treatment of amyloidgenic disease
US6750324B1 (en) * 1997-12-02 2004-06-15 Neuralab Limited Humanized and chimeric N-terminal amyloid beta-antibodies
AU2001270377A1 (en) 2000-06-20 2002-01-02 The Governing Council Of The University Of Toronto Transgenic animal model of neurodegenerative disorders
US6310810B1 (en) 2000-07-14 2001-10-30 Raj Kumar Jain High-speed sense amplifier
US6906169B2 (en) * 2001-05-25 2005-06-14 United Biomedical, Inc. Immunogenic peptide composition comprising measles virus Fprotein Thelper cell epitope (MUFThl-16) and N-terminus of β-amyloid peptide

Similar Documents

Publication Publication Date Title
JP2010065046A5 (enExample)
JP2006505502A5 (enExample)
JP2013503110A5 (enExample)
JP2014501510A5 (enExample)
JP2010534684A5 (enExample)
JP2010065037A5 (enExample)
JP2010535026A5 (enExample)
JP2009268467A5 (enExample)
JP2006149395A5 (enExample)
NZ593833A (en) Extended recombinant polypeptides and compositions comprising same
JP2010533478A5 (enExample)
JP2013539454A5 (enExample)
JP2011515449A5 (enExample)
JP2009225798A5 (enExample)
JP2009511579A5 (enExample)
JP2013048638A5 (enExample)
JP2008525033A5 (enExample)
JP2007513634A5 (enExample)
EA200870237A1 (ru) Последовательности пептидов и композиции
JP2009240315A5 (enExample)
JP2010265269A5 (enExample)
WO2007115175A3 (en) Cyclic natriuretic peptide constructs
JP2015505309A5 (enExample)
JP2015533791A5 (enExample)
JP2014529399A5 (enExample)