JP2009542696A5 - - Google Patents
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- JP2009542696A5 JP2009542696A5 JP2009518393A JP2009518393A JP2009542696A5 JP 2009542696 A5 JP2009542696 A5 JP 2009542696A5 JP 2009518393 A JP2009518393 A JP 2009518393A JP 2009518393 A JP2009518393 A JP 2009518393A JP 2009542696 A5 JP2009542696 A5 JP 2009542696A5
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- JP
- Japan
- Prior art keywords
- inhibitor
- group
- substituted
- alkyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 **N1CCOCC1 Chemical compound **N1CCOCC1 0.000 description 4
- GKOAQPMFDRAARM-ULKWEWGCSA-N CC(C)C1(C)SC=C(CN(C)C(N[C@@H](C(C)COC)C(O)=O)=O)N1 Chemical compound CC(C)C1(C)SC=C(CN(C)C(N[C@@H](C(C)COC)C(O)=O)=O)N1 GKOAQPMFDRAARM-ULKWEWGCSA-N 0.000 description 1
- AYNKEDQCQUBXKC-PXTZSQHASA-N CC(C)[C@@H](C(N(C)[C@H](CC[C@H](Cc1ccccc1)NC(OCc1cnc[s]1)=O)Cc1ccccc1)=O)NC(N(C)Cc1c[s]c(C(C)C)n1)=O Chemical compound CC(C)[C@@H](C(N(C)[C@H](CC[C@H](Cc1ccccc1)NC(OCc1cnc[s]1)=O)Cc1ccccc1)=O)NC(N(C)Cc1c[s]c(C(C)C)n1)=O AYNKEDQCQUBXKC-PXTZSQHASA-N 0.000 description 1
- FYFOKJMLOCALAN-QSCLJHCWSA-N CC(C)[C@@H](C(N[C@H](CC[C@H](Cc1ccccc1)NC(/[O]=C/c1cnc[s]1)=O)Cc1ccccc1)=O)NC(N(C)Cc1c[s]c(C(C)C)n1)=O Chemical compound CC(C)[C@@H](C(N[C@H](CC[C@H](Cc1ccccc1)NC(/[O]=C/c1cnc[s]1)=O)Cc1ccccc1)=O)NC(N(C)Cc1c[s]c(C(C)C)n1)=O FYFOKJMLOCALAN-QSCLJHCWSA-N 0.000 description 1
- MERJVZJITHOBLN-ZIHXJKBXSA-N CC(C)c1nc(CN(C)C(N[C@@H](C(C)OC)C(NCCC[C@H](Cc2ccccc2)NC(OCc2cnc[s]2)=O)=O)=O)c[s]1 Chemical compound CC(C)c1nc(CN(C)C(N[C@@H](C(C)OC)C(NCCC[C@H](Cc2ccccc2)NC(OCc2cnc[s]2)=O)=O)=O)c[s]1 MERJVZJITHOBLN-ZIHXJKBXSA-N 0.000 description 1
- WJGZIEIFZQIJPA-KFJBMODSSA-N CC(C)c1nc(CN(C)C(N[C@@H](C(C)OC)C(OC)=O)=O)c[s]1 Chemical compound CC(C)c1nc(CN(C)C(N[C@@H](C(C)OC)C(OC)=O)=O)c[s]1 WJGZIEIFZQIJPA-KFJBMODSSA-N 0.000 description 1
- LQRJNXNJJBAJRE-PUCLRWMGSA-N CC(C)c1nc(CN(C)C(N[C@@H](C/C(/O)=[O]/C)C(N[C@H](CC[C@H](Cc2ccccc2)NC(OCc2cnc[s]2)=O)Cc2ccccc2)=O)=O)c[s]1 Chemical compound CC(C)c1nc(CN(C)C(N[C@@H](C/C(/O)=[O]/C)C(N[C@H](CC[C@H](Cc2ccccc2)NC(OCc2cnc[s]2)=O)Cc2ccccc2)=O)=O)c[s]1 LQRJNXNJJBAJRE-PUCLRWMGSA-N 0.000 description 1
- UGINBIFFWPEJLE-GLGOKHISSA-N CC(C)c1nc(CN(C)C(N[C@H](C(C)OC(C)(C)C)C(O)=O)=O)c[s]1 Chemical compound CC(C)c1nc(CN(C)C(N[C@H](C(C)OC(C)(C)C)C(O)=O)=O)c[s]1 UGINBIFFWPEJLE-GLGOKHISSA-N 0.000 description 1
- FYCWLJLGIAUCCL-BKLSDQPFSA-N CC([C@@H](C(O)=O)N)OC Chemical compound CC([C@@H](C(O)=O)N)OC FYCWLJLGIAUCCL-BKLSDQPFSA-N 0.000 description 1
- ZGSFKAVIRXLMRI-AKGZTFGVSA-N CC([C@@H](C(OC)=O)N)OC Chemical compound CC([C@@H](C(OC)=O)N)OC ZGSFKAVIRXLMRI-AKGZTFGVSA-N 0.000 description 1
- IFKONDWPXROQGA-UHFFFAOYSA-N OC([n]1cncc1)=S Chemical compound OC([n]1cncc1)=S IFKONDWPXROQGA-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81931506P | 2006-07-07 | 2006-07-07 | |
| US60/819,315 | 2006-07-07 | ||
| US83237106P | 2006-07-21 | 2006-07-21 | |
| US60/832,371 | 2006-07-21 | ||
| US90322807P | 2007-02-23 | 2007-02-23 | |
| US60/903,228 | 2007-02-23 | ||
| PCT/US2007/015604 WO2008010921A2 (en) | 2006-07-07 | 2007-07-06 | Modulators of pharmacokinetic properties of therapeutics |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011239688A Division JP2012051933A (ja) | 2006-07-07 | 2011-10-31 | 治療薬の薬物動態の調整 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009542696A JP2009542696A (ja) | 2009-12-03 |
| JP2009542696A5 true JP2009542696A5 (enExample) | 2011-02-17 |
| JP4881433B2 JP4881433B2 (ja) | 2012-02-22 |
Family
ID=38729072
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009518393A Active JP4881433B2 (ja) | 2006-07-07 | 2007-07-06 | 治療薬の薬物動態の調整 |
| JP2011239688A Withdrawn JP2012051933A (ja) | 2006-07-07 | 2011-10-31 | 治療薬の薬物動態の調整 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011239688A Withdrawn JP2012051933A (ja) | 2006-07-07 | 2011-10-31 | 治療薬の薬物動態の調整 |
Country Status (33)
Families Citing this family (85)
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