CN101490023B - 治疗剂的药代动力学特性调节剂 - Google Patents
治疗剂的药代动力学特性调节剂 Download PDFInfo
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- CN101490023B CN101490023B CN2007800256073A CN200780025607A CN101490023B CN 101490023 B CN101490023 B CN 101490023B CN 2007800256073 A CN2007800256073 A CN 2007800256073A CN 200780025607 A CN200780025607 A CN 200780025607A CN 101490023 B CN101490023 B CN 101490023B
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- 0 CC(C)C1=*C(C*(C)C(*C(CCCCCCO)C(*(C)(C)[C@](CC[C@](Cc2ccccc2)*(C)(C)CC(OCC2=C*C=N2)=O)Cc2ccccc2)=O)=O)=C[U]1 Chemical compound CC(C)C1=*C(C*(C)C(*C(CCCCCCO)C(*(C)(C)[C@](CC[C@](Cc2ccccc2)*(C)(C)CC(OCC2=C*C=N2)=O)Cc2ccccc2)=O)=O)=C[U]1 0.000 description 13
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- BSZQZNOAYQCQFZ-QHCPKHFHSA-N N[C@@H](Cc1c[n](C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)C(O)=O Chemical compound N[C@@H](Cc1c[n](C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)C(O)=O BSZQZNOAYQCQFZ-QHCPKHFHSA-N 0.000 description 1
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- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
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- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
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| US83237106P | 2006-07-21 | 2006-07-21 | |
| US60/832,371 | 2006-07-21 | ||
| US90322807P | 2007-02-23 | 2007-02-23 | |
| US60/903,228 | 2007-02-23 | ||
| PCT/US2007/015604 WO2008010921A2 (en) | 2006-07-07 | 2007-07-06 | Modulators of pharmacokinetic properties of therapeutics |
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