JP2009540106A5 - - Google Patents
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- Publication number
- JP2009540106A5 JP2009540106A5 JP2009515512A JP2009515512A JP2009540106A5 JP 2009540106 A5 JP2009540106 A5 JP 2009540106A5 JP 2009515512 A JP2009515512 A JP 2009515512A JP 2009515512 A JP2009515512 A JP 2009515512A JP 2009540106 A5 JP2009540106 A5 JP 2009540106A5
- Authority
- JP
- Japan
- Prior art keywords
- glucan
- soluble
- composition
- suspension
- derivatized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims 12
- 229920002498 Beta-glucan Polymers 0.000 claims 12
- 238000000034 method Methods 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- 239000000725 suspension Substances 0.000 claims 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 230000003308 immunostimulating effect Effects 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- LOGFVTREOLYCPF-KXNHARMFSA-N (2s,3r)-2-[[(2r)-1-[(2s)-2,6-diaminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoic acid Chemical group C[C@@H](O)[C@@H](C(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](N)CCCCN LOGFVTREOLYCPF-KXNHARMFSA-N 0.000 claims 1
- 102000003777 Interleukin-1 beta Human genes 0.000 claims 1
- 108090000193 Interleukin-1 beta Proteins 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 1
- 238000005119 centrifugation Methods 0.000 claims 1
- 238000004587 chromatography analysis Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 230000002000 scavenging effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81397106P | 2006-06-15 | 2006-06-15 | |
| PCT/US2007/014055 WO2007146416A2 (en) | 2006-06-15 | 2007-06-15 | Glucan preparations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013228688A Division JP5851472B2 (ja) | 2006-06-15 | 2013-11-01 | グルカンの調製 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009540106A JP2009540106A (ja) | 2009-11-19 |
| JP2009540106A5 true JP2009540106A5 (enExample) | 2010-08-05 |
Family
ID=38832560
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009515512A Pending JP2009540106A (ja) | 2006-06-15 | 2007-06-15 | グルカンの調製 |
| JP2013228688A Expired - Fee Related JP5851472B2 (ja) | 2006-06-15 | 2013-11-01 | グルカンの調製 |
| JP2015235912A Expired - Fee Related JP6196280B2 (ja) | 2006-06-15 | 2015-12-02 | グルカンの調製 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013228688A Expired - Fee Related JP5851472B2 (ja) | 2006-06-15 | 2013-11-01 | グルカンの調製 |
| JP2015235912A Expired - Fee Related JP6196280B2 (ja) | 2006-06-15 | 2015-12-02 | グルカンの調製 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US9610303B2 (enExample) |
| EP (1) | EP2032180B1 (enExample) |
| JP (3) | JP2009540106A (enExample) |
| CN (2) | CN103833867B (enExample) |
| BR (1) | BRPI0713734A2 (enExample) |
| CA (1) | CA2655414C (enExample) |
| ES (1) | ES2628021T3 (enExample) |
| IL (2) | IL195937A (enExample) |
| MX (1) | MX2008016039A (enExample) |
| RU (1) | RU2490279C2 (enExample) |
| WO (2) | WO2007146416A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO20014256D0 (no) * | 2001-09-03 | 2001-09-03 | Bjoern Kristiansen | Fremstilling av immunstimulerende forbindelse |
| US7514085B2 (en) * | 2004-07-16 | 2009-04-07 | Medimush A/S | Immune modulating compounds from fungi |
| US9072776B2 (en) | 2005-06-15 | 2015-07-07 | Glycanova As | Anti-cancer combination treatment and kit-of-parts |
| EP1896601A1 (en) * | 2005-06-15 | 2008-03-12 | Medimush A/S | Bioactive agents produced by submerged cultivation of a basidiomycete cell |
| WO2007146416A2 (en) | 2006-06-15 | 2007-12-21 | Biopolymer Engineering, Inc. Dba Biothera, Inc. | Glucan preparations |
| US20080167268A1 (en) * | 2006-09-01 | 2008-07-10 | Jun Yan | Particulate beta-glucan compositions for regulating dendritic cells |
| WO2008027581A1 (en) * | 2006-09-01 | 2008-03-06 | University Of Louisville | Mcrp antagonists and their uses |
| CN101407559B (zh) * | 2008-11-25 | 2011-01-26 | 天津科技大学 | 一种快速制备酵母β-1,3-葡聚糖的方法 |
| FI20080665A0 (fi) * | 2008-12-18 | 2008-12-18 | Glykos Finland Oy | Luonnollisen tyyppiset sakkaridikoostumukset |
| JP5172930B2 (ja) * | 2009-10-20 | 2013-03-27 | 国立大学法人佐賀大学 | 高粘性培養液の粘性低下方法 |
| US9943607B2 (en) | 2011-05-09 | 2018-04-17 | Biothera, Inc. | Beta-glucan compounds, compositions, and methods |
| EP2714053B1 (en) | 2011-06-03 | 2020-12-09 | Hibercell, Inc. | Opsonized beta-glucan preparations and methods |
| HK1205466A1 (en) | 2012-02-22 | 2015-12-18 | Algal Scientific Corporation | Animal feed compositions and methods of using the same |
| CA2872010C (en) | 2012-04-30 | 2021-06-08 | Biothera, Inc. | Compositions and methods for .beta.-glucan immunotherapy |
| WO2015084732A1 (en) | 2013-12-05 | 2015-06-11 | Biothera, Inc. | β-GLUCAN ASSAY METHODS |
| LT6145B (lt) | 2014-04-14 | 2015-04-27 | Uab "Biocentras" | TERAPINĖ ß-GLIUKANŲ KOMPOZICIJA, MODULIUOJANTI ŽMOGAUS IMUNINĘ SISTEMĄ IR INICIJUOJANTI VĖŽINIŲ LĄSTELIŲ ARDYMĄ |
| EP3166616B1 (en) | 2014-07-10 | 2021-04-07 | Biothera, Inc. | Beta-glucan in combination with anti-cancer agents affecting the tumor microenvironment |
| ES2875338T3 (es) | 2014-11-06 | 2021-11-10 | Hibercell Inc | Métodos de beta-glucano y composiciones que afectan al microentorno tumoral |
| MY181390A (en) | 2014-11-19 | 2020-12-21 | Tablemark Co Ltd | Flavor improvement method for yeast cells and food quality imrproving agent |
| JP2016208909A (ja) * | 2015-05-08 | 2016-12-15 | 株式会社カネカ | 脂溶性生理活性物質の製造方法 |
| JP6935877B2 (ja) * | 2017-01-27 | 2021-09-15 | 日本製紙株式会社 | 免疫調整剤 |
| US11815435B2 (en) | 2017-02-24 | 2023-11-14 | Hibercell, Inc. | Beta glucan immunopharmacodynamics |
| MX2020009510A (es) | 2018-03-13 | 2021-08-05 | Hibercell Inc | Inmunoterapia combinada de beta glucano y agonista cd40. |
| JP6530846B1 (ja) * | 2018-10-09 | 2019-06-12 | アサヒグループホールディングス株式会社 | 免疫賦活剤及び感染予防方法 |
| US11140912B1 (en) | 2020-12-22 | 2021-10-12 | Agvault, Llc | Process for manufacturing yeast strains having increased mannan oligosaccharides and improved amino acid profiles |
| WO2023107712A1 (en) | 2021-12-10 | 2023-06-15 | Hibercell, Inc. | SOLUBLE β-GLUCANS FOR INDUCING TRAINED IMMUNITY |
| CN115028755B (zh) * | 2022-07-01 | 2023-08-11 | 福建省农业科学院食用菌研究所 | 一种高分子量绣球菌β-葡聚糖的制备方法 |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5082936A (en) | 1984-11-28 | 1992-01-21 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US4810646A (en) | 1984-11-28 | 1989-03-07 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
| US5028703A (en) | 1988-03-11 | 1991-07-02 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US5250436A (en) | 1984-11-28 | 1993-10-05 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
| US4962094A (en) | 1988-10-28 | 1990-10-09 | Alpha Beta Technology, Inc. | Glucan dietary additives |
| US5032401A (en) | 1989-06-15 | 1991-07-16 | Alpha Beta Technology | Glucan drug delivery system and adjuvant |
| JPH05502018A (ja) | 1989-09-08 | 1993-04-15 | アルファ ベータ テクノロジー，インコーポレイティッド | 免疫系活性化方法 |
| US5622939A (en) | 1992-08-21 | 1997-04-22 | Alpha-Beta Technology, Inc. | Glucan preparation |
| JPH05503952A (ja) | 1989-09-08 | 1993-06-24 | アルファ ベータ テクノロジー，インコーポレイティッド | 可溶性グルカン類の製造方法 |
| US5811542A (en) * | 1989-09-08 | 1998-09-22 | Alpha-Beta Technology, Inc. | Method for producing soluble glucans |
| US5488040A (en) | 1989-09-08 | 1996-01-30 | Alpha-Beta Technology, Inc. | Use of neutral soluble glucan preparations to stimulate platelet production |
| US6143731A (en) | 1989-10-20 | 2000-11-07 | The Collaborative Group, Ltd. | Glucan dietary additives |
| US6020324A (en) | 1989-10-20 | 2000-02-01 | The Collaborative Group, Ltd. | Glucan dietary additives |
| US5223491A (en) * | 1989-11-09 | 1993-06-29 | Donzis Byron A | Method for revitalizing skin by applying topically water insoluble glucan |
| JP2547220Y2 (ja) | 1990-07-19 | 1997-09-10 | 株式会社ユニシアジェックス | アクチュエータ |
| US5519009A (en) | 1993-10-01 | 1996-05-21 | Donzis; Byron A. | Solubilized yeast glucan |
| US5622940A (en) * | 1994-07-14 | 1997-04-22 | Alpha-Beta Technology | Inhibition of infection-stimulated oral tissue destruction by β(1,3)-glucan |
| US5576015A (en) | 1995-03-02 | 1996-11-19 | Donzis; Byron A. | Substantially purified beta (1,3) finely ground yeast cell wall glucan composition with dermatological and nutritional uses |
| AUPN166195A0 (en) * | 1995-03-13 | 1995-04-06 | Norvet Research Pty Limited | Process for glucan extraction |
| US6214337B1 (en) | 1995-04-18 | 2001-04-10 | Biotec Asa | Animal feeds comprising yeast glucan |
| US6117850A (en) | 1995-08-28 | 2000-09-12 | The Collaborative Group, Ltd. | Mobilization of peripheral blood precursor cells by β(1,3)-glucan |
| US6110692A (en) | 1996-05-01 | 2000-08-29 | The Collaborative Group, Ltd. | Receptor for underivatized aqueous soluble β(1-3)-glucan |
| US6084092A (en) * | 1997-01-31 | 2000-07-04 | The Collaborative Group, Ltd. | β(1-3)-glucan diagnostic assays |
| US6090938A (en) * | 1996-05-01 | 2000-07-18 | Collaborative Group, Ltd. | Activation of signal transduction by underivatized, aqueous soluble . .beta(1-3)-Glucan |
| US6413715B2 (en) | 1997-01-31 | 2002-07-02 | The Collaborative Group | β(1-3)-glucan diagnostic assays |
| US6046323A (en) | 1997-07-29 | 2000-04-04 | The Collaborative Group, Ltd. | Conformations of PPG-glucan |
| AU6261999A (en) | 1998-09-25 | 2000-04-17 | Collaborative Group, Ltd., The | Very high molecular weight beta-glucans |
| US6369216B1 (en) * | 1998-09-25 | 2002-04-09 | Biopolymer Engineering Pharmaceutical, Inc. | Very high molecular weight β-glucans |
| JP2002528062A (ja) * | 1998-10-26 | 2002-09-03 | セバ エービー | オートムギからβ−グルカン組成物を分離する方法及びそれから得られた生成物 |
| US6143883A (en) * | 1998-12-31 | 2000-11-07 | Marlyn Nutraceuticals, Inc. | Water-soluble low molecular weight beta-glucans for modulating immunological responses in mammalian system |
| JP2001342257A (ja) * | 2000-06-01 | 2001-12-11 | Fuji Photo Film Co Ltd | セルロース系ポリマーの製造方法 |
| JP2002105101A (ja) * | 2000-10-03 | 2002-04-10 | Ajinomoto Co Inc | 水溶性高分子の製造法 |
| US7786094B2 (en) | 2001-10-09 | 2010-08-31 | Biopolymer Engineering, Inc. | Use of beta-glucans against biological warfare weapons and pathogens including anthrax |
| US20070042930A1 (en) | 2002-08-13 | 2007-02-22 | Ross Gordon D | Effect of beta-glucan on stem cell recruitment and tissue repair |
| EP1545208A4 (en) | 2002-08-13 | 2006-04-12 | Biopolymer Engineering Inc | METHODS OF USING BETA-GLUCAN AS RADIOPROTECTIVE AGENT |
| US20060165700A1 (en) | 2002-09-04 | 2006-07-27 | Ostroff Gary R | Cancer therapy using whole glucan particles and antibodies |
| CN1694715B (zh) | 2002-09-04 | 2010-12-01 | 路易斯维尔大学研究基金会 | β葡聚糖和抗体在制备治疗癌性的药物中的用途 |
| CA2501820C (en) * | 2002-10-08 | 2009-12-15 | Ricom Corporation | Chitosan-containing polysaccharide, method for preparing the same and use thereof |
| EP1721990B1 (en) * | 2004-02-13 | 2009-03-18 | Alpron Co., Ltd | Process for producing yeast-derived glucan |
| WO2006085895A2 (en) | 2004-05-10 | 2006-08-17 | Biopolymer Engineering, Inc. | Whole glucan particles in combination with antibiotics, vaccines and viral monoclonal antibodies |
| GB0411880D0 (en) | 2004-05-27 | 2004-06-30 | Imagination Tech Ltd | Method and apparatus for efficient evaluation of "table-based" mathematical functions |
| FI20040804A7 (fi) * | 2004-06-11 | 2005-12-12 | Cerefract Oy | Menetelmä viljan ainesosan erottamiseksi |
| US20050020490A1 (en) * | 2004-10-18 | 2005-01-27 | Progressive Bioactives Incorporated | A Method of Producing an Economical and Ecologically Sound Natural Immunobiotic Extract for Use as a Health Management Instrument and a Replacement for Growth Promotion Antibiotics in Livestock and Companion Animals. |
| EP1917019A2 (en) | 2005-05-03 | 2008-05-07 | Biopolymer Engineering, Inc. | Combination of a beta-glucan and an egf receptor antagonist for the treatment of cancer and infection |
| KR20080106160A (ko) | 2005-11-01 | 2008-12-04 | 씨피 켈코 유에스, 인코포레이티드 | 변성 카르복시메틸셀룰로오스 물질로 제조된 필름 및 캡슐및 그의 제조방법 |
| WO2007146417A2 (en) | 2006-06-15 | 2007-12-21 | Biopolymer Engineering, Inc. Dba Biothera, Inc. | Glucan compositions and methods of enhancing cr3 dependent neutrophil-mediated cytotoxicity |
| WO2007146416A2 (en) | 2006-06-15 | 2007-12-21 | Biopolymer Engineering, Inc. Dba Biothera, Inc. | Glucan preparations |
| US20080167268A1 (en) | 2006-09-01 | 2008-07-10 | Jun Yan | Particulate beta-glucan compositions for regulating dendritic cells |
| WO2008027581A1 (en) | 2006-09-01 | 2008-03-06 | University Of Louisville | Mcrp antagonists and their uses |
| EP2146744A4 (en) | 2007-04-24 | 2012-07-25 | Univ Louisville Res Found | THERAPEUTIC BETA-GLUCAN COMPOSITIONS |
| UA101617C2 (ru) | 2007-05-08 | 2013-04-25 | Байополимер Инджиниринг, Инк. Дба Байотера, Инк. | Способ получения растворимого бета-глюкана |
| EP2200736B1 (de) | 2007-10-08 | 2016-11-30 | Basf Se | Verfahren zur herstellung von formkörpern mit katalytischen eigenschaften als reaktoreinbauten |
-
2007
- 2007-06-15 WO PCT/US2007/014055 patent/WO2007146416A2/en not_active Ceased
- 2007-06-15 CN CN201310718360.0A patent/CN103833867B/zh not_active Expired - Fee Related
- 2007-06-15 EP EP07796157.1A patent/EP2032180B1/en active Active
- 2007-06-15 CN CN200780029944.XA patent/CN101553261B/zh not_active Expired - Fee Related
- 2007-06-15 MX MX2008016039A patent/MX2008016039A/es active IP Right Grant
- 2007-06-15 JP JP2009515512A patent/JP2009540106A/ja active Pending
- 2007-06-15 CA CA2655414A patent/CA2655414C/en active Active
- 2007-06-15 ES ES07796157.1T patent/ES2628021T3/es active Active
- 2007-06-15 US US11/818,741 patent/US9610303B2/en active Active
- 2007-06-15 WO PCT/US2007/014191 patent/WO2007146440A2/en not_active Ceased
- 2007-06-15 RU RU2009101051/10A patent/RU2490279C2/ru active
- 2007-06-15 US US11/818,804 patent/US20080108114A1/en not_active Abandoned
- 2007-06-15 BR BRPI0713734-6A patent/BRPI0713734A2/pt not_active Application Discontinuation
-
2008
- 2008-12-15 IL IL195937A patent/IL195937A/en active IP Right Grant
-
2013
- 2013-11-01 JP JP2013228688A patent/JP5851472B2/ja not_active Expired - Fee Related
-
2015
- 2015-01-22 IL IL236842A patent/IL236842A/en active IP Right Grant
- 2015-12-02 JP JP2015235912A patent/JP6196280B2/ja not_active Expired - Fee Related
-
2017
- 2017-02-21 US US15/437,778 patent/US10272101B2/en active Active
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