CA2655414C - Glucan preparations - Google Patents

Glucan preparations Download PDF

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Publication number
CA2655414C
CA2655414C CA2655414A CA2655414A CA2655414C CA 2655414 C CA2655414 C CA 2655414C CA 2655414 A CA2655414 A CA 2655414A CA 2655414 A CA2655414 A CA 2655414A CA 2655414 C CA2655414 C CA 2655414C
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CA
Canada
Prior art keywords
glucan
beta
soluble
underivatized
less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2655414A
Other languages
English (en)
French (fr)
Other versions
CA2655414A1 (en
Inventor
Andrew Magee
James Rolke
Ren-Der Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biothera Inc
Original Assignee
Biothera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biothera Inc filed Critical Biothera Inc
Publication of CA2655414A1 publication Critical patent/CA2655414A1/en
Application granted granted Critical
Publication of CA2655414C publication Critical patent/CA2655414C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
CA2655414A 2006-06-15 2007-06-15 Glucan preparations Active CA2655414C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81397106P 2006-06-15 2006-06-15
US60/813,971 2006-06-15
PCT/US2007/014055 WO2007146416A2 (en) 2006-06-15 2007-06-15 Glucan preparations

Publications (2)

Publication Number Publication Date
CA2655414A1 CA2655414A1 (en) 2007-12-21
CA2655414C true CA2655414C (en) 2019-04-23

Family

ID=38832560

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2655414A Active CA2655414C (en) 2006-06-15 2007-06-15 Glucan preparations

Country Status (11)

Country Link
US (3) US9610303B2 (enExample)
EP (1) EP2032180B1 (enExample)
JP (3) JP2009540106A (enExample)
CN (2) CN103833867B (enExample)
BR (1) BRPI0713734A2 (enExample)
CA (1) CA2655414C (enExample)
ES (1) ES2628021T3 (enExample)
IL (2) IL195937A (enExample)
MX (1) MX2008016039A (enExample)
RU (1) RU2490279C2 (enExample)
WO (2) WO2007146416A2 (enExample)

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EP1896601A1 (en) * 2005-06-15 2008-03-12 Medimush A/S Bioactive agents produced by submerged cultivation of a basidiomycete cell
WO2007146416A2 (en) 2006-06-15 2007-12-21 Biopolymer Engineering, Inc. Dba Biothera, Inc. Glucan preparations
US20080167268A1 (en) * 2006-09-01 2008-07-10 Jun Yan Particulate beta-glucan compositions for regulating dendritic cells
WO2008027581A1 (en) * 2006-09-01 2008-03-06 University Of Louisville Mcrp antagonists and their uses
CN101407559B (zh) * 2008-11-25 2011-01-26 天津科技大学 一种快速制备酵母β-1,3-葡聚糖的方法
FI20080665A0 (fi) * 2008-12-18 2008-12-18 Glykos Finland Oy Luonnollisen tyyppiset sakkaridikoostumukset
JP5172930B2 (ja) * 2009-10-20 2013-03-27 国立大学法人佐賀大学 高粘性培養液の粘性低下方法
US9943607B2 (en) 2011-05-09 2018-04-17 Biothera, Inc. Beta-glucan compounds, compositions, and methods
EP2714053B1 (en) 2011-06-03 2020-12-09 Hibercell, Inc. Opsonized beta-glucan preparations and methods
HK1205466A1 (en) 2012-02-22 2015-12-18 Algal Scientific Corporation Animal feed compositions and methods of using the same
CA2872010C (en) 2012-04-30 2021-06-08 Biothera, Inc. Compositions and methods for .beta.-glucan immunotherapy
WO2015084732A1 (en) 2013-12-05 2015-06-11 Biothera, Inc. β-GLUCAN ASSAY METHODS
LT6145B (lt) 2014-04-14 2015-04-27 Uab "Biocentras" TERAPINĖ ß-GLIUKANŲ KOMPOZICIJA, MODULIUOJANTI ŽMOGAUS IMUNINĘ SISTEMĄ IR INICIJUOJANTI VĖŽINIŲ LĄSTELIŲ ARDYMĄ
EP3166616B1 (en) 2014-07-10 2021-04-07 Biothera, Inc. Beta-glucan in combination with anti-cancer agents affecting the tumor microenvironment
ES2875338T3 (es) 2014-11-06 2021-11-10 Hibercell Inc Métodos de beta-glucano y composiciones que afectan al microentorno tumoral
MY181390A (en) 2014-11-19 2020-12-21 Tablemark Co Ltd Flavor improvement method for yeast cells and food quality imrproving agent
JP2016208909A (ja) * 2015-05-08 2016-12-15 株式会社カネカ 脂溶性生理活性物質の製造方法
JP6935877B2 (ja) * 2017-01-27 2021-09-15 日本製紙株式会社 免疫調整剤
US11815435B2 (en) 2017-02-24 2023-11-14 Hibercell, Inc. Beta glucan immunopharmacodynamics
MX2020009510A (es) 2018-03-13 2021-08-05 Hibercell Inc Inmunoterapia combinada de beta glucano y agonista cd40.
JP6530846B1 (ja) * 2018-10-09 2019-06-12 アサヒグループホールディングス株式会社 免疫賦活剤及び感染予防方法
US11140912B1 (en) 2020-12-22 2021-10-12 Agvault, Llc Process for manufacturing yeast strains having increased mannan oligosaccharides and improved amino acid profiles
WO2023107712A1 (en) 2021-12-10 2023-06-15 Hibercell, Inc. SOLUBLE β-GLUCANS FOR INDUCING TRAINED IMMUNITY
CN115028755B (zh) * 2022-07-01 2023-08-11 福建省农业科学院食用菌研究所 一种高分子量绣球菌β-葡聚糖的制备方法

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Also Published As

Publication number Publication date
US20170304352A1 (en) 2017-10-26
WO2007146440A2 (en) 2007-12-21
JP5851472B2 (ja) 2016-02-03
WO2007146416A3 (en) 2008-03-13
CN101553261A (zh) 2009-10-07
WO2007146440A3 (en) 2008-02-07
MX2008016039A (es) 2009-07-10
EP2032180A4 (en) 2013-05-22
WO2007146416B1 (en) 2008-04-24
JP2009540106A (ja) 2009-11-19
EP2032180A2 (en) 2009-03-11
JP2014025079A (ja) 2014-02-06
CN103833867B (zh) 2017-07-04
RU2490279C2 (ru) 2013-08-20
IL236842A (en) 2017-04-30
US10272101B2 (en) 2019-04-30
BRPI0713734A2 (pt) 2012-11-06
HK1138215A1 (en) 2010-08-20
JP6196280B2 (ja) 2017-09-13
WO2007146440B1 (en) 2008-03-20
WO2007146416A2 (en) 2007-12-21
IL195937A0 (en) 2009-09-01
CN101553261B (zh) 2014-01-29
US20080108114A1 (en) 2008-05-08
IL195937A (en) 2016-04-21
AU2007258191A1 (en) 2007-12-21
US20080103112A1 (en) 2008-05-01
CA2655414A1 (en) 2007-12-21
CN103833867A (zh) 2014-06-04
EP2032180B1 (en) 2017-03-15
RU2009101051A (ru) 2010-07-20
US9610303B2 (en) 2017-04-04
ES2628021T3 (es) 2017-08-01
JP2016053080A (ja) 2016-04-14

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