IL195937A - Soluble beta-glucan production processes and soluble beta-glucan preparations without immunocompromising properties - Google Patents
Soluble beta-glucan production processes and soluble beta-glucan preparations without immunocompromising propertiesInfo
- Publication number
- IL195937A IL195937A IL195937A IL19593708A IL195937A IL 195937 A IL195937 A IL 195937A IL 195937 A IL195937 A IL 195937A IL 19593708 A IL19593708 A IL 19593708A IL 195937 A IL195937 A IL 195937A
- Authority
- IL
- Israel
- Prior art keywords
- glucan
- soluble beta
- underivatized
- processes
- composition
- Prior art date
Links
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 title 2
- 229920002498 Beta-glucan Polymers 0.000 title 2
- 230000003308 immunostimulating effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81397106P | 2006-06-15 | 2006-06-15 | |
| PCT/US2007/014055 WO2007146416A2 (en) | 2006-06-15 | 2007-06-15 | Glucan preparations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL195937A0 IL195937A0 (en) | 2009-09-01 |
| IL195937A true IL195937A (en) | 2016-04-21 |
Family
ID=38832560
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL195937A IL195937A (en) | 2006-06-15 | 2008-12-15 | Soluble beta-glucan production processes and soluble beta-glucan preparations without immunocompromising properties |
| IL236842A IL236842A (en) | 2006-06-15 | 2015-01-22 | A process for making beta-glucans and their preparations |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL236842A IL236842A (en) | 2006-06-15 | 2015-01-22 | A process for making beta-glucans and their preparations |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US9610303B2 (enExample) |
| EP (1) | EP2032180B1 (enExample) |
| JP (3) | JP2009540106A (enExample) |
| CN (2) | CN103833867B (enExample) |
| BR (1) | BRPI0713734A2 (enExample) |
| CA (1) | CA2655414C (enExample) |
| ES (1) | ES2628021T3 (enExample) |
| IL (2) | IL195937A (enExample) |
| MX (1) | MX2008016039A (enExample) |
| RU (1) | RU2490279C2 (enExample) |
| WO (2) | WO2007146440A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO20014256D0 (no) | 2001-09-03 | 2001-09-03 | Bjoern Kristiansen | Fremstilling av immunstimulerende forbindelse |
| US7514085B2 (en) | 2004-07-16 | 2009-04-07 | Medimush A/S | Immune modulating compounds from fungi |
| EP1896600A2 (en) | 2005-06-15 | 2008-03-12 | Medimush A/S | Anti-cancer combination treatment and kit-of-part |
| WO2006133708A1 (en) * | 2005-06-15 | 2006-12-21 | Medimush A/S | Bioactive agents produced by submerged cultivation of a basidiomycete cell |
| JP2009540106A (ja) | 2006-06-15 | 2009-11-19 | バイオポリマー エンジニアリング インコーポレイテッド ディービーエイ バイオセラ インコーポレイテッド | グルカンの調製 |
| WO2008027580A2 (en) * | 2006-09-01 | 2008-03-06 | University Of Louisville | PARTICULATE β-GLUCAN COMPOSITIONS FOR REGULATING DENDRITIC CELLS |
| US20080063650A1 (en) * | 2006-09-01 | 2008-03-13 | Jun Yan | mCRP antagonists and their uses |
| CN101407559B (zh) * | 2008-11-25 | 2011-01-26 | 天津科技大学 | 一种快速制备酵母β-1,3-葡聚糖的方法 |
| FI20080665A0 (fi) * | 2008-12-18 | 2008-12-18 | Glykos Finland Oy | Luonnollisen tyyppiset sakkaridikoostumukset |
| JP5172930B2 (ja) * | 2009-10-20 | 2013-03-27 | 国立大学法人佐賀大学 | 高粘性培養液の粘性低下方法 |
| WO2012154818A1 (en) | 2011-05-09 | 2012-11-15 | Biothera, Inc. | B-glucan compounds, compositions, and methods |
| EP2714053B1 (en) | 2011-06-03 | 2020-12-09 | Hibercell, Inc. | Opsonized beta-glucan preparations and methods |
| IN2014DN07419A (enExample) | 2012-02-22 | 2015-04-24 | Algal Scient Corp | |
| AU2013257139B2 (en) | 2012-04-30 | 2018-02-22 | Biothera, Inc. | Beta-glucan immunotherapeutic methods |
| WO2015084732A1 (en) | 2013-12-05 | 2015-06-11 | Biothera, Inc. | β-GLUCAN ASSAY METHODS |
| LT6145B (lt) | 2014-04-14 | 2015-04-27 | Uab "Biocentras" | TERAPINĖ ß-GLIUKANŲ KOMPOZICIJA, MODULIUOJANTI ŽMOGAUS IMUNINĘ SISTEMĄ IR INICIJUOJANTI VĖŽINIŲ LĄSTELIŲ ARDYMĄ |
| EP3166616B1 (en) | 2014-07-10 | 2021-04-07 | Biothera, Inc. | Beta-glucan in combination with anti-cancer agents affecting the tumor microenvironment |
| JP6887378B2 (ja) | 2014-11-06 | 2021-06-16 | バイオセラ,インク. | 腫瘍内微小環境に影響を与えるベータ−グルカン方法と組成物 |
| TWI674070B (zh) | 2014-11-19 | 2019-10-11 | 日商泰寶美客股份有限公司 | 酵母細胞之風味改善方法及食品品質改良劑 |
| JP2016208909A (ja) * | 2015-05-08 | 2016-12-15 | 株式会社カネカ | 脂溶性生理活性物質の製造方法 |
| JP6935877B2 (ja) * | 2017-01-27 | 2021-09-15 | 日本製紙株式会社 | 免疫調整剤 |
| WO2018156888A1 (en) | 2017-02-24 | 2018-08-30 | Biothera Pharmaceuticals, Inc. | Beta glucan immunopharmacodynamics |
| MX2020009510A (es) | 2018-03-13 | 2021-08-05 | Hibercell Inc | Inmunoterapia combinada de beta glucano y agonista cd40. |
| JP6530846B1 (ja) * | 2018-10-09 | 2019-06-12 | アサヒグループホールディングス株式会社 | 免疫賦活剤及び感染予防方法 |
| US11140912B1 (en) | 2020-12-22 | 2021-10-12 | Agvault, Llc | Process for manufacturing yeast strains having increased mannan oligosaccharides and improved amino acid profiles |
| WO2023107712A1 (en) | 2021-12-10 | 2023-06-15 | Hibercell, Inc. | SOLUBLE β-GLUCANS FOR INDUCING TRAINED IMMUNITY |
| CN115028755B (zh) * | 2022-07-01 | 2023-08-11 | 福建省农业科学院食用菌研究所 | 一种高分子量绣球菌β-葡聚糖的制备方法 |
Family Cites Families (52)
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|---|---|---|---|---|
| US4810646A (en) | 1984-11-28 | 1989-03-07 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
| US5250436A (en) | 1984-11-28 | 1993-10-05 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
| US5028703A (en) | 1988-03-11 | 1991-07-02 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US5082936A (en) | 1984-11-28 | 1992-01-21 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US4962094A (en) | 1988-10-28 | 1990-10-09 | Alpha Beta Technology, Inc. | Glucan dietary additives |
| US5032401A (en) * | 1989-06-15 | 1991-07-16 | Alpha Beta Technology | Glucan drug delivery system and adjuvant |
| JPH05503952A (ja) | 1989-09-08 | 1993-06-24 | アルファ ベータ テクノロジー,インコーポレイティッド | 可溶性グルカン類の製造方法 |
| US5811542A (en) | 1989-09-08 | 1998-09-22 | Alpha-Beta Technology, Inc. | Method for producing soluble glucans |
| US5622939A (en) * | 1992-08-21 | 1997-04-22 | Alpha-Beta Technology, Inc. | Glucan preparation |
| CA2067159A1 (en) | 1989-09-08 | 1991-03-09 | Spiros Jamas | Method for immune system activation |
| US5488040A (en) | 1989-09-08 | 1996-01-30 | Alpha-Beta Technology, Inc. | Use of neutral soluble glucan preparations to stimulate platelet production |
| US6143731A (en) * | 1989-10-20 | 2000-11-07 | The Collaborative Group, Ltd. | Glucan dietary additives |
| US6020324A (en) * | 1989-10-20 | 2000-02-01 | The Collaborative Group, Ltd. | Glucan dietary additives |
| US5223491A (en) * | 1989-11-09 | 1993-06-29 | Donzis Byron A | Method for revitalizing skin by applying topically water insoluble glucan |
| JP2547220Y2 (ja) | 1990-07-19 | 1997-09-10 | 株式会社ユニシアジェックス | アクチュエータ |
| US5519009A (en) * | 1993-10-01 | 1996-05-21 | Donzis; Byron A. | Solubilized yeast glucan |
| US5622940A (en) * | 1994-07-14 | 1997-04-22 | Alpha-Beta Technology | Inhibition of infection-stimulated oral tissue destruction by β(1,3)-glucan |
| US5576015A (en) | 1995-03-02 | 1996-11-19 | Donzis; Byron A. | Substantially purified beta (1,3) finely ground yeast cell wall glucan composition with dermatological and nutritional uses |
| AUPN166195A0 (en) * | 1995-03-13 | 1995-04-06 | Norvet Research Pty Limited | Process for glucan extraction |
| US6214337B1 (en) | 1995-04-18 | 2001-04-10 | Biotec Asa | Animal feeds comprising yeast glucan |
| US6117850A (en) | 1995-08-28 | 2000-09-12 | The Collaborative Group, Ltd. | Mobilization of peripheral blood precursor cells by β(1,3)-glucan |
| US6110692A (en) | 1996-05-01 | 2000-08-29 | The Collaborative Group, Ltd. | Receptor for underivatized aqueous soluble β(1-3)-glucan |
| US6090938A (en) | 1996-05-01 | 2000-07-18 | Collaborative Group, Ltd. | Activation of signal transduction by underivatized, aqueous soluble . .beta(1-3)-Glucan |
| US6084092A (en) | 1997-01-31 | 2000-07-04 | The Collaborative Group, Ltd. | β(1-3)-glucan diagnostic assays |
| US6413715B2 (en) | 1997-01-31 | 2002-07-02 | The Collaborative Group | β(1-3)-glucan diagnostic assays |
| US6046323A (en) * | 1997-07-29 | 2000-04-04 | The Collaborative Group, Ltd. | Conformations of PPG-glucan |
| AU6261999A (en) | 1998-09-25 | 2000-04-17 | Collaborative Group, Ltd., The | Very high molecular weight beta-glucans |
| US6369216B1 (en) | 1998-09-25 | 2002-04-09 | Biopolymer Engineering Pharmaceutical, Inc. | Very high molecular weight β-glucans |
| AU760172B2 (en) * | 1998-10-26 | 2003-05-08 | Oatly Ab | Method for the isolation of a beta-glucan composition from oats and products made therefrom |
| US6143883A (en) | 1998-12-31 | 2000-11-07 | Marlyn Nutraceuticals, Inc. | Water-soluble low molecular weight beta-glucans for modulating immunological responses in mammalian system |
| JP2001342257A (ja) * | 2000-06-01 | 2001-12-11 | Fuji Photo Film Co Ltd | セルロース系ポリマーの製造方法 |
| JP2002105101A (ja) | 2000-10-03 | 2002-04-10 | Ajinomoto Co Inc | 水溶性高分子の製造法 |
| US7786094B2 (en) | 2001-10-09 | 2010-08-31 | Biopolymer Engineering, Inc. | Use of beta-glucans against biological warfare weapons and pathogens including anthrax |
| US20070042930A1 (en) | 2002-08-13 | 2007-02-22 | Ross Gordon D | Effect of beta-glucan on stem cell recruitment and tissue repair |
| WO2004014320A2 (en) * | 2002-08-13 | 2004-02-19 | Biopolymer Engineering, Inc. | Methods of using beta glucan as a radioprotective agent |
| US20060165700A1 (en) | 2002-09-04 | 2006-07-27 | Ostroff Gary R | Cancer therapy using whole glucan particles and antibodies |
| AU2003295326A1 (en) | 2002-09-04 | 2004-04-23 | Cancer therapy using beta glucan and antibodies | |
| KR100674672B1 (ko) | 2002-10-08 | 2007-01-29 | 가부시끼가이샤 리코무 | 키토산 함유 다당, 그 제조방법 및 용도 |
| ATE426037T1 (de) * | 2004-02-13 | 2009-04-15 | Alpron Co Ltd | Verfahren zur herstellung von aus hefe stammendem glucan |
| CN1964722A (zh) | 2004-05-10 | 2007-05-16 | 生物聚合物工程有限公司 | 与抗生素、疫苗和病毒单克隆抗体组合的全葡聚糖颗粒 |
| GB0411880D0 (en) | 2004-05-27 | 2004-06-30 | Imagination Tech Ltd | Method and apparatus for efficient evaluation of "table-based" mathematical functions |
| FI20040804L (fi) | 2004-06-11 | 2005-12-12 | Glubikan Ab Oy | Menetelmä viljan ainesosan erottamiseksi |
| US20050020490A1 (en) * | 2004-10-18 | 2005-01-27 | Progressive Bioactives Incorporated | A Method of Producing an Economical and Ecologically Sound Natural Immunobiotic Extract for Use as a Health Management Instrument and a Replacement for Growth Promotion Antibiotics in Livestock and Companion Animals. |
| EP1917019A2 (en) | 2005-05-03 | 2008-05-07 | Biopolymer Engineering, Inc. | Combination of a beta-glucan and an egf receptor antagonist for the treatment of cancer and infection |
| AP2878A (en) | 2005-11-01 | 2014-03-31 | Cp Kelco Us Inc | High viscocity diutan gums and methods of producing |
| JP2009540106A (ja) | 2006-06-15 | 2009-11-19 | バイオポリマー エンジニアリング インコーポレイテッド ディービーエイ バイオセラ インコーポレイテッド | グルカンの調製 |
| US20090047288A1 (en) | 2006-06-15 | 2009-02-19 | Jun Yan | Glucan compositions and methods of enhancing CR3 dependent neutrophil-mediated cytotoxicity |
| WO2008027580A2 (en) | 2006-09-01 | 2008-03-06 | University Of Louisville | PARTICULATE β-GLUCAN COMPOSITIONS FOR REGULATING DENDRITIC CELLS |
| US20080063650A1 (en) | 2006-09-01 | 2008-03-13 | Jun Yan | mCRP antagonists and their uses |
| US20090074761A1 (en) | 2007-04-24 | 2009-03-19 | Jun Yan | Therapeutic beta-glucan combinations |
| UA101617C2 (ru) | 2007-05-08 | 2013-04-25 | Байополимер Инджиниринг, Инк. Дба Байотера, Инк. | Способ получения растворимого бета-глюкана |
| EP2200736B1 (de) | 2007-10-08 | 2016-11-30 | Basf Se | Verfahren zur herstellung von formkörpern mit katalytischen eigenschaften als reaktoreinbauten |
-
2007
- 2007-06-15 JP JP2009515512A patent/JP2009540106A/ja active Pending
- 2007-06-15 CA CA2655414A patent/CA2655414C/en active Active
- 2007-06-15 EP EP07796157.1A patent/EP2032180B1/en active Active
- 2007-06-15 BR BRPI0713734-6A patent/BRPI0713734A2/pt not_active Application Discontinuation
- 2007-06-15 MX MX2008016039A patent/MX2008016039A/es active IP Right Grant
- 2007-06-15 WO PCT/US2007/014191 patent/WO2007146440A2/en not_active Ceased
- 2007-06-15 WO PCT/US2007/014055 patent/WO2007146416A2/en not_active Ceased
- 2007-06-15 US US11/818,741 patent/US9610303B2/en active Active
- 2007-06-15 US US11/818,804 patent/US20080108114A1/en not_active Abandoned
- 2007-06-15 CN CN201310718360.0A patent/CN103833867B/zh not_active Expired - Fee Related
- 2007-06-15 ES ES07796157.1T patent/ES2628021T3/es active Active
- 2007-06-15 RU RU2009101051/10A patent/RU2490279C2/ru active
- 2007-06-15 CN CN200780029944.XA patent/CN101553261B/zh not_active Expired - Fee Related
-
2008
- 2008-12-15 IL IL195937A patent/IL195937A/en active IP Right Grant
-
2013
- 2013-11-01 JP JP2013228688A patent/JP5851472B2/ja not_active Expired - Fee Related
-
2015
- 2015-01-22 IL IL236842A patent/IL236842A/en active IP Right Grant
- 2015-12-02 JP JP2015235912A patent/JP6196280B2/ja not_active Expired - Fee Related
-
2017
- 2017-02-21 US US15/437,778 patent/US10272101B2/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed |