ES2628021T3 - Preparaciones de glucano - Google Patents
Preparaciones de glucano Download PDFInfo
- Publication number
- ES2628021T3 ES2628021T3 ES07796157.1T ES07796157T ES2628021T3 ES 2628021 T3 ES2628021 T3 ES 2628021T3 ES 07796157 T ES07796157 T ES 07796157T ES 2628021 T3 ES2628021 T3 ES 2628021T3
- Authority
- ES
- Spain
- Prior art keywords
- glucan
- soluble
- acid
- composition
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000463 material Substances 0.000 claims description 14
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- 238000004587 chromatography analysis Methods 0.000 claims description 6
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- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
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- NQXWGWZJXJUMQB-UHFFFAOYSA-K iron trichloride hexahydrate Chemical compound O.O.O.O.O.O.[Cl-].Cl[Fe+]Cl NQXWGWZJXJUMQB-UHFFFAOYSA-K 0.000 description 1
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- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
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- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Polymers & Plastics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
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| PCT/US2007/014055 WO2007146416A2 (en) | 2006-06-15 | 2007-06-15 | Glucan preparations |
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| ES2628021T3 true ES2628021T3 (es) | 2017-08-01 |
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| ES07796157.1T Active ES2628021T3 (es) | 2006-06-15 | 2007-06-15 | Preparaciones de glucano |
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| JP (3) | JP2009540106A (enExample) |
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| BR (1) | BRPI0713734A2 (enExample) |
| CA (1) | CA2655414C (enExample) |
| ES (1) | ES2628021T3 (enExample) |
| IL (2) | IL195937A (enExample) |
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| RU (1) | RU2490279C2 (enExample) |
| WO (2) | WO2007146416A2 (enExample) |
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| NO20014256D0 (no) * | 2001-09-03 | 2001-09-03 | Bjoern Kristiansen | Fremstilling av immunstimulerende forbindelse |
| US7514085B2 (en) * | 2004-07-16 | 2009-04-07 | Medimush A/S | Immune modulating compounds from fungi |
| US9072776B2 (en) | 2005-06-15 | 2015-07-07 | Glycanova As | Anti-cancer combination treatment and kit-of-parts |
| EP1896601A1 (en) * | 2005-06-15 | 2008-03-12 | Medimush A/S | Bioactive agents produced by submerged cultivation of a basidiomycete cell |
| WO2007146416A2 (en) | 2006-06-15 | 2007-12-21 | Biopolymer Engineering, Inc. Dba Biothera, Inc. | Glucan preparations |
| US20080167268A1 (en) * | 2006-09-01 | 2008-07-10 | Jun Yan | Particulate beta-glucan compositions for regulating dendritic cells |
| WO2008027581A1 (en) * | 2006-09-01 | 2008-03-06 | University Of Louisville | Mcrp antagonists and their uses |
| CN101407559B (zh) * | 2008-11-25 | 2011-01-26 | 天津科技大学 | 一种快速制备酵母β-1,3-葡聚糖的方法 |
| FI20080665A0 (fi) * | 2008-12-18 | 2008-12-18 | Glykos Finland Oy | Luonnollisen tyyppiset sakkaridikoostumukset |
| JP5172930B2 (ja) * | 2009-10-20 | 2013-03-27 | 国立大学法人佐賀大学 | 高粘性培養液の粘性低下方法 |
| US9943607B2 (en) | 2011-05-09 | 2018-04-17 | Biothera, Inc. | Beta-glucan compounds, compositions, and methods |
| EP2714053B1 (en) | 2011-06-03 | 2020-12-09 | Hibercell, Inc. | Opsonized beta-glucan preparations and methods |
| HK1205466A1 (en) | 2012-02-22 | 2015-12-18 | Algal Scientific Corporation | Animal feed compositions and methods of using the same |
| CA2872010C (en) | 2012-04-30 | 2021-06-08 | Biothera, Inc. | Compositions and methods for .beta.-glucan immunotherapy |
| WO2015084732A1 (en) | 2013-12-05 | 2015-06-11 | Biothera, Inc. | β-GLUCAN ASSAY METHODS |
| LT6145B (lt) | 2014-04-14 | 2015-04-27 | Uab "Biocentras" | TERAPINĖ ß-GLIUKANŲ KOMPOZICIJA, MODULIUOJANTI ŽMOGAUS IMUNINĘ SISTEMĄ IR INICIJUOJANTI VĖŽINIŲ LĄSTELIŲ ARDYMĄ |
| EP3166616B1 (en) | 2014-07-10 | 2021-04-07 | Biothera, Inc. | Beta-glucan in combination with anti-cancer agents affecting the tumor microenvironment |
| ES2875338T3 (es) | 2014-11-06 | 2021-11-10 | Hibercell Inc | Métodos de beta-glucano y composiciones que afectan al microentorno tumoral |
| MY181390A (en) | 2014-11-19 | 2020-12-21 | Tablemark Co Ltd | Flavor improvement method for yeast cells and food quality imrproving agent |
| JP2016208909A (ja) * | 2015-05-08 | 2016-12-15 | 株式会社カネカ | 脂溶性生理活性物質の製造方法 |
| JP6935877B2 (ja) * | 2017-01-27 | 2021-09-15 | 日本製紙株式会社 | 免疫調整剤 |
| US11815435B2 (en) | 2017-02-24 | 2023-11-14 | Hibercell, Inc. | Beta glucan immunopharmacodynamics |
| MX2020009510A (es) | 2018-03-13 | 2021-08-05 | Hibercell Inc | Inmunoterapia combinada de beta glucano y agonista cd40. |
| JP6530846B1 (ja) * | 2018-10-09 | 2019-06-12 | アサヒグループホールディングス株式会社 | 免疫賦活剤及び感染予防方法 |
| US11140912B1 (en) | 2020-12-22 | 2021-10-12 | Agvault, Llc | Process for manufacturing yeast strains having increased mannan oligosaccharides and improved amino acid profiles |
| WO2023107712A1 (en) | 2021-12-10 | 2023-06-15 | Hibercell, Inc. | SOLUBLE β-GLUCANS FOR INDUCING TRAINED IMMUNITY |
| CN115028755B (zh) * | 2022-07-01 | 2023-08-11 | 福建省农业科学院食用菌研究所 | 一种高分子量绣球菌β-葡聚糖的制备方法 |
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| US5082936A (en) | 1984-11-28 | 1992-01-21 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US4810646A (en) | 1984-11-28 | 1989-03-07 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
| US5028703A (en) | 1988-03-11 | 1991-07-02 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US5250436A (en) | 1984-11-28 | 1993-10-05 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
| US4962094A (en) | 1988-10-28 | 1990-10-09 | Alpha Beta Technology, Inc. | Glucan dietary additives |
| US5032401A (en) | 1989-06-15 | 1991-07-16 | Alpha Beta Technology | Glucan drug delivery system and adjuvant |
| JPH05502018A (ja) | 1989-09-08 | 1993-04-15 | アルファ ベータ テクノロジー，インコーポレイティッド | 免疫系活性化方法 |
| US5622939A (en) | 1992-08-21 | 1997-04-22 | Alpha-Beta Technology, Inc. | Glucan preparation |
| JPH05503952A (ja) | 1989-09-08 | 1993-06-24 | アルファ ベータ テクノロジー，インコーポレイティッド | 可溶性グルカン類の製造方法 |
| US5811542A (en) * | 1989-09-08 | 1998-09-22 | Alpha-Beta Technology, Inc. | Method for producing soluble glucans |
| US5488040A (en) | 1989-09-08 | 1996-01-30 | Alpha-Beta Technology, Inc. | Use of neutral soluble glucan preparations to stimulate platelet production |
| US6143731A (en) | 1989-10-20 | 2000-11-07 | The Collaborative Group, Ltd. | Glucan dietary additives |
| US6020324A (en) | 1989-10-20 | 2000-02-01 | The Collaborative Group, Ltd. | Glucan dietary additives |
| US5223491A (en) * | 1989-11-09 | 1993-06-29 | Donzis Byron A | Method for revitalizing skin by applying topically water insoluble glucan |
| JP2547220Y2 (ja) | 1990-07-19 | 1997-09-10 | 株式会社ユニシアジェックス | アクチュエータ |
| US5519009A (en) | 1993-10-01 | 1996-05-21 | Donzis; Byron A. | Solubilized yeast glucan |
| US5622940A (en) * | 1994-07-14 | 1997-04-22 | Alpha-Beta Technology | Inhibition of infection-stimulated oral tissue destruction by β(1,3)-glucan |
| US5576015A (en) | 1995-03-02 | 1996-11-19 | Donzis; Byron A. | Substantially purified beta (1,3) finely ground yeast cell wall glucan composition with dermatological and nutritional uses |
| AUPN166195A0 (en) * | 1995-03-13 | 1995-04-06 | Norvet Research Pty Limited | Process for glucan extraction |
| US6214337B1 (en) | 1995-04-18 | 2001-04-10 | Biotec Asa | Animal feeds comprising yeast glucan |
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| US6110692A (en) | 1996-05-01 | 2000-08-29 | The Collaborative Group, Ltd. | Receptor for underivatized aqueous soluble β(1-3)-glucan |
| US6084092A (en) * | 1997-01-31 | 2000-07-04 | The Collaborative Group, Ltd. | β(1-3)-glucan diagnostic assays |
| US6090938A (en) * | 1996-05-01 | 2000-07-18 | Collaborative Group, Ltd. | Activation of signal transduction by underivatized, aqueous soluble . .beta(1-3)-Glucan |
| US6413715B2 (en) | 1997-01-31 | 2002-07-02 | The Collaborative Group | β(1-3)-glucan diagnostic assays |
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2007
- 2007-06-15 WO PCT/US2007/014055 patent/WO2007146416A2/en not_active Ceased
- 2007-06-15 CN CN201310718360.0A patent/CN103833867B/zh not_active Expired - Fee Related
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- 2007-06-15 RU RU2009101051/10A patent/RU2490279C2/ru active
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