JP2009534420A - Ｉｌ−８受容体アンタゴニスト - Google Patents
Ｉｌ−８受容体アンタゴニスト Download PDFInfo
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- JP2009534420A JP2009534420A JP2009506793A JP2009506793A JP2009534420A JP 2009534420 A JP2009534420 A JP 2009534420A JP 2009506793 A JP2009506793 A JP 2009506793A JP 2009506793 A JP2009506793 A JP 2009506793A JP 2009534420 A JP2009534420 A JP 2009534420A
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- Prior art keywords
- chloro
- urea
- hydroxyphenyl
- phenyl
- oct
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Classifications
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
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- Organic Chemistry (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79383606P | 2006-04-21 | 2006-04-21 | |
| PCT/US2007/067088 WO2007124423A2 (en) | 2006-04-21 | 2007-04-20 | Il-8 receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009534420A true JP2009534420A (ja) | 2009-09-24 |
| JP2009534420A5 JP2009534420A5 (enExample) | 2010-06-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009506793A Pending JP2009534420A (ja) | 2006-04-21 | 2007-04-20 | Ｉｌ−８受容体アンタゴニスト |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8097626B2 (enExample) |
| EP (1) | EP2010180A4 (enExample) |
| JP (1) | JP2009534420A (enExample) |
| CN (1) | CN101495113A (enExample) |
| AU (1) | AU2007240364A1 (enExample) |
| BR (1) | BRPI0710559A2 (enExample) |
| CA (1) | CA2650007A1 (enExample) |
| IL (1) | IL194700A0 (enExample) |
| MX (1) | MX2008013599A (enExample) |
| RU (1) | RU2008145871A (enExample) |
| WO (1) | WO2007124423A2 (enExample) |
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| JP2013521284A (ja) * | 2010-03-01 | 2013-06-10 | ノヴァドラッグ，エルエルシー | ウィルス性疾患の治療のための組成物及び方法 |
| JP2013545790A (ja) * | 2010-12-17 | 2013-12-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医薬としての二環系置換スルホンアミド官能化フェノール |
| JP2013545789A (ja) * | 2010-12-17 | 2013-12-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医薬としての二環系置換アミド官能化フェノール |
| JP2021510164A (ja) * | 2018-01-11 | 2021-04-15 | メッドシャイン ディスカバリー インコーポレイテッド | Ｃｘｃｒ２アンタゴニスト |
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| EP2009992B1 (en) | 2006-04-21 | 2012-06-27 | GlaxoSmithKline LLC | Il-8 receptor antagonists |
| MX2008013599A (es) | 2006-04-21 | 2008-10-31 | Smithkline Beechman Corp | Antagonistas del receptor il-8. |
| TW201035102A (en) * | 2009-03-04 | 2010-10-01 | Gruenethal Gmbh | Sulfonylated tetrahydroazolopyrazines and their use as medicinal products |
| JO3156B1 (ar) | 2009-07-09 | 2017-09-20 | Novartis Ag | ايميدازولات مدمجة والتركيبات التي تشملها لعلاج الأمراض الطفيلية على مثال الملاريا |
| US9241930B2 (en) | 2011-08-24 | 2016-01-26 | Novadrug, Llc | Compositions and methods for treating viral diseases |
| KR20150002713A (ko) | 2012-03-28 | 2015-01-07 | 뉴로포레 테라피스, 인코포레이티드 | 단백질 응집 저해제로서의 페닐-우레아 및 페닐-카바메이트 유도체 |
| US10167293B2 (en) * | 2016-05-26 | 2019-01-01 | Bayer Pharma Aktiengesellschaft | [8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanones |
| EA036824B1 (ru) * | 2016-07-11 | 2020-12-24 | Байер Фарма Акциенгезельшафт | [8-(фенилсульфонил)-3,8-диазабицикло[3.2.1]окт-3-ил](1н-1,2,3-триазол-4-ил)метаноны |
| AU2018235937A1 (en) * | 2017-03-15 | 2019-09-19 | Lunella Biotech, Inc. | Mitoriboscins: mitochondrial-based therapeutics targeting cancer cells, bacteria, and pathogenic yeast |
| EP3615030A1 (en) | 2017-04-24 | 2020-03-04 | Novartis AG | Therapeutic regimen of 2-amino-l-(2-(4-fluorophenyl)-3-(4-fluorophenylamino)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8h)-yl)ethanone and combinations thereof |
| WO2021004531A1 (zh) * | 2019-07-11 | 2021-01-14 | 南京明德新药研发有限公司 | 一种cxcr2拮抗剂的晶型及其应用 |
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- 2007-04-20 AU AU2007240364A patent/AU2007240364A1/en not_active Abandoned
- 2007-04-20 CN CNA2007800232115A patent/CN101495113A/zh active Pending
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- 2007-04-20 WO PCT/US2007/067088 patent/WO2007124423A2/en not_active Ceased
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- 2007-04-20 BR BRPI0710559-2A patent/BRPI0710559A2/pt not_active IP Right Cessation
- 2007-04-20 RU RU2008145871/04A patent/RU2008145871A/ru not_active Application Discontinuation
- 2007-04-20 JP JP2009506793A patent/JP2009534420A/ja active Pending
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| JP2009534421A (ja) * | 2006-04-21 | 2009-09-24 | スミスクライン・ビーチャム・コーポレイション | Ｉｌ−８受容体アンタゴニスト |
Cited By (5)
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| JP2021510164A (ja) * | 2018-01-11 | 2021-04-15 | メッドシャイン ディスカバリー インコーポレイテッド | Ｃｘｃｒ２アンタゴニスト |
| JP7223764B2 (ja) | 2018-01-11 | 2023-02-16 | シェンチェン オプティマム バイオロジカル テクノロジー カンパニー，リミティド | Ｃｘｃｒ２アンタゴニスト |
Also Published As
| Publication number | Publication date |
|---|---|
| US8097626B2 (en) | 2012-01-17 |
| IL194700A0 (en) | 2009-08-03 |
| AU2007240364A1 (en) | 2007-11-01 |
| BRPI0710559A2 (pt) | 2011-08-16 |
| EP2010180A4 (en) | 2010-10-13 |
| WO2007124423A2 (en) | 2007-11-01 |
| CN101495113A (zh) | 2009-07-29 |
| RU2008145871A (ru) | 2010-05-27 |
| US20090298810A1 (en) | 2009-12-03 |
| MX2008013599A (es) | 2008-10-31 |
| WO2007124423A3 (en) | 2009-04-09 |
| CA2650007A1 (en) | 2007-11-01 |
| EP2010180A2 (en) | 2009-01-07 |
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