JP2009530613A5 - - Google Patents
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- Publication number
- JP2009530613A5 JP2009530613A5 JP2009500495A JP2009500495A JP2009530613A5 JP 2009530613 A5 JP2009530613 A5 JP 2009530613A5 JP 2009500495 A JP2009500495 A JP 2009500495A JP 2009500495 A JP2009500495 A JP 2009500495A JP 2009530613 A5 JP2009530613 A5 JP 2009530613A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- gelsolin
- level
- composition
- multiple sclerosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004878 Gelsolin Human genes 0.000 claims 20
- 108090001064 Gelsolin Proteins 0.000 claims 20
- 201000006417 multiple sclerosis Diseases 0.000 claims 13
- 210000001124 body fluid Anatomy 0.000 claims 5
- 239000010839 body fluid Substances 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 208000012902 Nervous system disease Diseases 0.000 claims 4
- 208000025966 Neurological disease Diseases 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78250906P | 2006-03-15 | 2006-03-15 | |
| PCT/US2007/006581 WO2007106577A2 (en) | 2006-03-15 | 2007-03-14 | Gelsolin in the treatment and diagnosis of neurological disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011271607A Division JP6203995B2 (ja) | 2006-03-15 | 2011-12-12 | 多発性硬化症を治療するため、および神経疾患を診断するための、ゲルゾリンの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009530613A JP2009530613A (ja) | 2009-08-27 |
| JP2009530613A5 true JP2009530613A5 (enExample) | 2010-05-06 |
Family
ID=38510104
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009500495A Pending JP2009530613A (ja) | 2006-03-15 | 2007-03-14 | 多発性硬化症を治療するため、および神経疾患を診断するための、ゲルゾリンの使用 |
| JP2011271607A Active JP6203995B2 (ja) | 2006-03-15 | 2011-12-12 | 多発性硬化症を治療するため、および神経疾患を診断するための、ゲルゾリンの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011271607A Active JP6203995B2 (ja) | 2006-03-15 | 2011-12-12 | 多発性硬化症を治療するため、および神経疾患を診断するための、ゲルゾリンの使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8440622B2 (enExample) |
| EP (1) | EP2002258B1 (enExample) |
| JP (2) | JP2009530613A (enExample) |
| CN (1) | CN101460843B (enExample) |
| CA (1) | CA2680333C (enExample) |
| DK (1) | DK2002258T3 (enExample) |
| ES (1) | ES2651619T3 (enExample) |
| HU (1) | HUE035980T2 (enExample) |
| PL (1) | PL2002258T3 (enExample) |
| PT (1) | PT2002258T (enExample) |
| WO (1) | WO2007106577A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9408891B2 (en) * | 2003-11-12 | 2016-08-09 | The Trustees Of The University Of Pennsylvania | Methods of using gelsolin to treat or prevent bacterial sepsis |
| ES2848385T3 (es) * | 2003-11-12 | 2021-08-09 | Univ Pennsylvania | Métodos de uso de gelsolina para tratar o prevenir septicemia bacteriana |
| CA2607686C (en) | 2004-05-12 | 2014-11-04 | Thomas P. Stossel | Use of gelsolin to treat infections |
| JP4348631B2 (ja) * | 2005-03-29 | 2009-10-21 | セイコーエプソン株式会社 | 半導体素子の製造方法 |
| AU2007227613A1 (en) | 2006-03-15 | 2007-09-27 | The Brigham And Women's Hospital, Inc. | Use of gelsolin to diagnose and treat inflammatory diseases |
| JP5778425B2 (ja) | 2008-01-25 | 2015-09-16 | ザ ジェネラル ホスピタル コーポレイション | 腎不全におけるゲルソリンの診断的および治療的使用 |
| WO2009124226A2 (en) * | 2008-04-03 | 2009-10-08 | The Trustees Of The University Of Pennsylvania | Gelsolin uses in neurological disorders |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| DE102010026500A1 (de) * | 2010-07-07 | 2012-01-12 | Arthrogen Gmbh | Verfahren zur Herstellung von autologen Proteinen |
| EP3279668B1 (en) * | 2010-12-16 | 2019-05-15 | National Institute of Advanced Industrial Science and Technology | Method for enrichment and separation of spinal fluid glycoprotein, method for searching for marker for central nervous system diseases which utilizes the aforementioned method, and marker for central nervous system diseases |
| KR101416954B1 (ko) | 2012-09-12 | 2014-07-16 | 한양대학교 산학협력단 | 조혈세포 분화 유도 방법 |
| WO2015137738A1 (ko) * | 2014-03-11 | 2015-09-17 | 한양대학교 산학협력단 | 혈액질환 진단 |
| FR3036188B1 (fr) * | 2015-05-12 | 2019-06-07 | Biomerieux | Prediction du risque de developper, pour des patients admis en service de reanimation, une infection disseminee |
| JP6947449B2 (ja) * | 2016-06-29 | 2021-10-13 | 学校法人自治医科大学 | バイオマーカー、診断用組成物、及び診断用キット |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| HRP20250396T1 (hr) | 2016-08-31 | 2025-05-23 | Mapi Pharma Ltd. | Depo sustavi koji sadrže glatiramer acetat |
| AU2018242998B2 (en) | 2017-03-26 | 2023-11-02 | Mapi Pharma Ltd. | Glatiramer depot systems for treating progressive forms of multiple sclerosis |
| WO2019173258A1 (en) * | 2018-03-05 | 2019-09-12 | Academia Sinica | Methods and kits for diagnosing and/or treating peripheral neuropathy |
| WO2020263484A1 (en) * | 2019-06-28 | 2020-12-30 | Mayo Foundation For Medical Education And Research | Methods and materials for treating neuromyelitis optica spectrum diseases |
| EP4204818A1 (en) * | 2020-09-23 | 2023-07-05 | Bioaegis Therapeutics Inc. | Compositions and methods for identifying and treating microparticle-associated diseases and conditions |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US627353A (en) * | 1899-06-20 | Cis robinson | ||
| US5071773A (en) | 1986-10-24 | 1991-12-10 | The Salk Institute For Biological Studies | Hormone receptor-related bioassays |
| CA2016227A1 (en) | 1989-05-18 | 1990-11-18 | Xandra O. Breakefield | Genetic diagnosis of torsion dystonia |
| US5464817A (en) | 1990-04-11 | 1995-11-07 | Brigham And Women's Hospital | Method for reducing the viscosity of pathological mucoid airway contents in the respiratory tract comprising administering actin-binding compounds with or without DNASE I |
| ATE171625T1 (de) | 1990-04-11 | 1998-10-15 | Brigham & Womens Hospital | Therapeutische verwendung von actin-bindenden verbindungen |
| JPH05501503A (ja) | 1990-05-04 | 1993-03-25 | バイオジェン,インコーポレイテッド | 多量体ゲルゾリン融合構築物 |
| US5571511A (en) | 1990-10-22 | 1996-11-05 | The U.S. Government | Broadly reactive opsonic antibodies that react with common staphylococcal antigens |
| JP3507486B2 (ja) | 1991-03-15 | 2004-03-15 | アムジエン・インコーポレーテツド | 顆粒球コロニー刺激因子の肺内投与 |
| US5360350A (en) | 1991-08-23 | 1994-11-01 | The Whitaker Corporation | Sealant compositions and sealed electrical connectors |
| US5691160A (en) | 1992-08-14 | 1997-11-25 | Biogen, Inc. | Effects of actin filaments of fibrin clot structure and lysis |
| US5593964A (en) | 1993-10-07 | 1997-01-14 | The George Washington University Medical Center | Method of treating septic shock by preventing actin polymerization |
| JP3914272B2 (ja) | 1993-12-28 | 2007-05-16 | 中外製薬株式会社 | アドゼベリンをコードする遺伝子 |
| US5451569A (en) | 1994-04-19 | 1995-09-19 | Hong Kong University Of Science And Technology R & D Corporation Limited | Pulmonary drug delivery system |
| US5846743A (en) | 1995-02-22 | 1998-12-08 | Brigham And Women's Hospital, Inc. | Polyphoshoinositide binding peptides for intracellular drug delivery |
| US5804427A (en) | 1995-05-19 | 1998-09-08 | University Of Massachusetts | Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases |
| US5925529A (en) | 1995-06-07 | 1999-07-20 | The Regents Of The University Of California | Method for discovery of peptide agonists |
| US5569588A (en) | 1995-08-09 | 1996-10-29 | The Regents Of The University Of California | Methods for drug screening |
| US5750353A (en) | 1995-12-11 | 1998-05-12 | New England Medical Center Hospitals, Inc. | Assay for non-peptide agonists to peptide hormone receptors |
| JP2001505219A (ja) | 1996-12-04 | 2001-04-17 | ザ・ビクトリア・ユニバーシティ・オブ・マンチェスター | 創傷の治癒および線維症の治療 |
| EP1003501B9 (en) | 1997-04-02 | 2005-06-08 | The Brigham And Women's Hospital, Inc. | Use of an agent for lowering the risk of cardiovascular disease |
| AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| US6409599B1 (en) | 1999-07-19 | 2002-06-25 | Ham On Rye Technologies, Inc. | Interactive virtual reality performance theater entertainment system |
| JP2004532386A (ja) | 2001-01-26 | 2004-10-21 | オックスフォード グリコサイエンシズ(ユーケー)リミテッド | 多発性硬化症を診断および治療するためのタンパク質、遺伝子、およびこれらの使用 |
| EP1249244A1 (en) | 2001-04-13 | 2002-10-16 | Universiteit Gent | Therapeutic compositions for the treatment of a disease modulated by the G-actin / F-actin equilibrium, especially a respiratory tract disease |
| EP2266595A3 (en) | 2002-02-06 | 2011-07-06 | Regenerx Biopharmaceuticals, Inc. | Treatment of infections and other disorders |
| WO2003088811A2 (en) | 2002-04-16 | 2003-10-30 | The Brigham And Women's Hospital, Inc. | Gelsolin as a prognostic marker of artherosclerotic diseases |
| AU2003253014A1 (en) | 2002-06-21 | 2004-01-06 | Innogenetics N.V. | Method for the diagnosis and differential diagnosis of neurological diseases |
| AU2003289716A1 (en) | 2002-09-12 | 2004-04-30 | Incyte Corporation | Molecules for diagnostics and therapeutics |
| EP1627076A4 (en) | 2003-03-14 | 2008-07-02 | Ppd Biomarker Discovery Scienc | BIOLOGICAL MARKERS FOR THE DIAGNOSIS OF RHEUMATOID ARTHRITIS |
| ES2848385T3 (es) | 2003-11-12 | 2021-08-09 | Univ Pennsylvania | Métodos de uso de gelsolina para tratar o prevenir septicemia bacteriana |
| US9408891B2 (en) | 2003-11-12 | 2016-08-09 | The Trustees Of The University Of Pennsylvania | Methods of using gelsolin to treat or prevent bacterial sepsis |
| CA2607686C (en) | 2004-05-12 | 2014-11-04 | Thomas P. Stossel | Use of gelsolin to treat infections |
| EP1753455A2 (en) * | 2004-06-04 | 2007-02-21 | Genentech, Inc. | Method for treating multiple sclerosis |
| WO2007041245A2 (en) * | 2005-09-29 | 2007-04-12 | Biogen Idec Ma Inc. | Biomarkers for multiple sclerosis and methods of use thereof |
| AU2007227613A1 (en) | 2006-03-15 | 2007-09-27 | The Brigham And Women's Hospital, Inc. | Use of gelsolin to diagnose and treat inflammatory diseases |
| JP5778425B2 (ja) | 2008-01-25 | 2015-09-16 | ザ ジェネラル ホスピタル コーポレイション | 腎不全におけるゲルソリンの診断的および治療的使用 |
-
2007
- 2007-03-14 EP EP07753226.5A patent/EP2002258B1/en active Active
- 2007-03-14 CN CN200780017675.5A patent/CN101460843B/zh active Active
- 2007-03-14 US US12/225,132 patent/US8440622B2/en active Active
- 2007-03-14 PT PT77532265T patent/PT2002258T/pt unknown
- 2007-03-14 CA CA2680333A patent/CA2680333C/en active Active
- 2007-03-14 DK DK07753226.5T patent/DK2002258T3/en active
- 2007-03-14 PL PL07753226T patent/PL2002258T3/pl unknown
- 2007-03-14 JP JP2009500495A patent/JP2009530613A/ja active Pending
- 2007-03-14 HU HUE07753226A patent/HUE035980T2/hu unknown
- 2007-03-14 ES ES07753226.5T patent/ES2651619T3/es active Active
- 2007-03-14 WO PCT/US2007/006581 patent/WO2007106577A2/en not_active Ceased
-
2011
- 2011-12-12 JP JP2011271607A patent/JP6203995B2/ja active Active
-
2013
- 2013-04-12 US US13/861,578 patent/US20130230455A1/en not_active Abandoned
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